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https://www.readbyqxmd.com/read/27933343/-conservative-treatment-of-congenital-patellar-dislocation
#1
D Zajonz, E Schumann, M Wojan, M Moche, C-E Heyde
This article presents the rare case of a boy who was born in our hospital with valgus deformity and external rotation of the right lower leg because of congenital patellar dislocation. In the case presented a stable repositioning of the patella could be achieved by redressment with a plaster cast and leg brace. During a 4-year follow-up there were no tendencies towards dislocation during the clinical examination and no dislocation events were documented. In selected cases an attempt at conservative repositioning and retention treatment appears to be worthwhile before surgical treatment is indicated...
December 8, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27933263/manifold-regularization-for-sparse-unmixing-of-hyperspectral-images
#2
Junmin Liu, Chunxia Zhang, Jiangshe Zhang, Huirong Li, Yuelin Gao
BACKGROUND: Recently, sparse unmixing has been successfully applied to spectral mixture analysis of remotely sensed hyperspectral images. Based on the assumption that the observed image signatures can be expressed in the form of linear combinations of a number of pure spectral signatures known in advance, unmixing of each mixed pixel in the scene is to find an optimal subset of signatures in a very large spectral library, which is cast into the framework of sparse regression. However, traditional sparse regression models, such as collaborative sparse regression, ignore the intrinsic geometric structure in the hyperspectral data...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27932679/tendon-collagen-synthesis-declines-with-immobilization-in-elderly-humans-no-effect-of-anti-inflammatory-medication
#3
Kasper Dideriksen, Anders Ploug Boesen, Søren Reitelseder, Christian Couppe, Rene Brüggebusch Svensson, Peter Schjerling, S Peter Magnusson, Lars Holm, Michael Kjaer
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAID) are used as pain killers during periods of unloading caused by traumatic occurrences or diseases. However, it is unknown how the tendon protein turnover and mechanical properties responds to unloading and subsequent loading in elderly humans, and especially whether NSAIDs affect tendon adaptation during such periods. Thus, we studied the influence of NSAID upon the human patellar tendon protein synthesis and mechanical properties during immobilization and subsequent rehabilitating resistance training...
December 8, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27932510/embolization-of-intracranial-dural-arteriovenous-fistulas-using-phil-liquid-embolic-agent-in-26-patients-a-multicenter-study
#4
S Lamin, H S Chew, S Chavda, A Thomas, M Piano, L Quilici, G Pero, M Holtmannspolter, M E Cronqvist, A Casasco, L Guimaraens, L Paul, A Gil Garcia, A Aleu, R Chapot
BACKGROUND AND PURPOSE: The introduction of liquid embolic agents has revolutionized endovascular approach to cranial vascular malformations. The aim of the study was to retrospectively assess the efficacy and safety of Precipitating Hydrophobic Injectable Liquid (PHIL), a new nonadhesive liquid embolic agent, in the treatment of patients with cranial dural arteriovenous fistulas. The primary end point was the rate of complete occlusion of dural arteriovenous fistulas. Secondary end points included the incidence of adverse events and clinical status at 3-month follow-up...
December 8, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27932013/socio-economic-inequalities-in-health-and-health-service-use-among-older-adults-in-india-results-from-the-who-study-on-global-ageing-and-adult-health-survey
#5
E M Brinda, J Attermann, U G Gerdtham, U Enemark
OBJECTIVE: The objectives of this study were to measure socio-economic inequalities in self-reported health (SRH) and healthcare visits and to identify factors contributing to health inequalities among older people aged 50-plus years. STUDY DESIGN: This study is based on a population-based, cross-sectional survey. METHODS: We accessed data of 7150 older adults from the World Health Organization's Study on Global AGEing and adult health Indian survey...
December 2016: Public Health
https://www.readbyqxmd.com/read/27930810/alamandine-abrogates-neutrophil-degranulation-in-atherosclerotic-mice
#6
Analina R Da Silva, Sébastien Lenglet, Federico Carbone, Fabienne Burger, Aline Roth, Luca Liberale, Aldo Bonaventura, Franco Dallegri, Nikolaos Stergiopulos, Robson A S Santos, François Mach, Rodrigo A Fraga-Silva, Fabrizio Montecucco
Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In this study, we investigated whether treatment with the recently discovered agonist of the Mas-related G-coupled receptor type D (MrgD) alamandine would impact on neutrophil degranulation in vivo and in vitro MATERIALS AND METHODS: Fifteen-week old ApoE-/- mice were fed with a Western-type diet for an additional 11 weeks...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27930663/livephantom-retrieving-virtual-world-light-data-to-real-environments
#7
Hoshang Kolivand, Mark Billinghurst, Mohd Shahrizal Sunar
To achieve realistic Augmented Reality (AR), shadows play an important role in creating a 3D impression of a scene. Casting virtual shadows on real and virtual objects is one of the topics of research being conducted in this area. In this paper, we propose a new method for creating complex AR indoor scenes using real time depth detection to exert virtual shadows on virtual and real environments. A Kinect camera was used to produce a depth map for the physical scene mixing into a single real-time transparent tacit surface...
2016: PloS One
https://www.readbyqxmd.com/read/27929104/microneedles-with-controlled-bubble-sizes-and-drug-distributions-for-efficient-transdermal-drug-delivery
#8
Qi Lei Wang, Dan Dan Zhu, Xu Bo Liu, Bo Zhi Chen, Xin Dong Guo
Drug loaded dissolving microneedles (DMNs) fabricated with water soluble polymers have received increasing attentions as a safe and efficient transdermal drug delivery system. Usually, to reach a high drug delivery efficiency, an ideal drug distribution is gathering more drugs in the tip or the top part of DMNs. In this work, we introduce an easy and new method to introduce a bubble with controlled size into the body of DMNs. The introduction of bubbles can prevent the drug diffusion into the whole body of the MNs...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27928108/bonding-durability-between-acrylic-resin-adhesives-and-titanium-with-surface-preparations
#9
Hiroaki Yanagida, Yoshito Minesaki, Kousuke Matsumura, Naomi Tanoue, Koichi Muraguchi, Hiroyuki Minami
The purpose of the present study was to evaluate the efficacy of pretreatment on the bonding durability between titanium casting and two acrylic adhesives. Cast titanium disk specimens treated with four polymer-metal bonding systems as follow: 1) air-abraded with 50-70 μm alumina, 2) 1)+Alloy Primer, 3) 1)+M.L. Primer and 4) tribochemical silica/silane coating system (Rocatec System). The specimens were bonded with M bond or Super-bond C&B adhesive. The shear bond strengths were determined before and after thermocycling (20,000 cycles)...
December 6, 2016: Dental Materials Journal
https://www.readbyqxmd.com/read/27928031/multi-casting-approach-for-vascular-networks-in-cellularized-hydrogels
#10
Alexander W Justin, Roger A Brooks, Athina E Markaki
Vascularization is essential for living tissue and remains a major challenge in the field of tissue engineering. A lack of a perfusable channel network within a large and densely populated tissue engineered construct leads to necrotic core formation, preventing fabrication of functional tissues and organs. We report a new method for producing a hierarchical, three-dimensional (3D) and perfusable vasculature in a large, cellularized fibrin hydrogel. Bifurcating channels, varying in size from 1 mm to 200-250 µm, are formed using a novel process in which we convert a 3D printed thermoplastic material into a gelatin network template, by way of an intermediate alginate hydrogel...
December 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27927704/nogo-a-regulates-vascular-network-architecture-in-the-postnatal-brain
#11
Thomas Wälchli, Alexandra Ulmann-Schuler, Christoph Hintermüller, Eric Meyer, Marco Stampanoni, Peter Carmeliet, Maximilian Y Emmert, Oliver Bozinov, Luca Regli, Martin E Schwab, Johannes Vogel, Simon P Hoerstrup
Recently, we discovered a new role for the well-known axonal growth inhibitory molecule Nogo-A as a negative regulator of angiogenesis in the developing central nervous system. However, how Nogo-A affected the three-dimensional (3D) central nervous system (CNS) vascular network architecture remained unknown. Here, using vascular corrosion casting, hierarchical, synchrotron radiation μCT-based network imaging and computer-aided network analysis, we found that genetic ablation of Nogo-A significantly increased the three-dimensional vascular volume fraction in the postnatal day 10 (P10) mouse brain...
November 10, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27927286/effect-of-casting-atmosphere-on-the-marginal-deficiency-and-misfit-of-ni-cr-alloys-with-and-without-beryllium
#12
Leandro J da Silva, Monica B Leal, Mariana L C Valente, Denise T de Castro, Valéria O Pagnano, Andréa C Dos Reis, Osvaldo L Bezzon
STATEMENT OF PROBLEM: The marginal adaptation of prosthetic crowns is still a significant clinical problem. PURPOSE: The purpose of this in vitro study was to evaluate the marginal deficiency and misfit of Ni-Cr alloys with and without beryllium under different casting conditions. MATERIAL AND METHODS: Four casting conditions were selected: flame-torch, induction/argon, induction/vacuum, and induction/air; and 2 alloys were used, Ni-Cr-Be and Ni-Cr...
December 4, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27927283/bond-strengths-of-porcelain-to-cobalt-chromium-alloys-made-by-casting-milling-and-selective-laser-melting
#13
Jieyin Li, Chaojie Chen, Juankun Liao, Lang Liu, Xiuhua Ye, Shiyao Lin, Jiantao Ye
STATEMENT OF PROBLEM: Cobalt-chromium (Co-Cr) alloys have been widely used for metal ceramic fixed prostheses and can be fabricated using conventionally cast or new computer-aided technology. However, the effect of different manufacturing methods on the metal-ceramic bond strength needs further evaluation. PURPOSE: The purpose of this in vitro study was to evaluate the metal-ceramic bond strength of a Co-Cr alloy made by casting, milling, and selective laser melting (SLM)...
December 4, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27925440/enhancing-bioactive-properties-of-silk-fibroin-with-diatom-particles-for-bone-tissue-engineering-applications
#14
Thi Duy Hanh Le, Volha Liaudanskaya, Walter Bonani, Claudio Migliaresi, Antonella Motta
Many studies have highlighted the role of silicon in human bone formation and maintenance. Silicon, in fact, is considered to nucleate the precipitation of hydroxyapatite and to reduce the bone resorption. For this reason, we have combined silk fibroin with silicon releasing diatom particles, as potential material for bone tissue engineering applications. Sponges of fibroin loaded with different amounts and sizes of diatom particles were prepared by solvent casting-particulate leaching method, and their morphology, porosity and mechanical properties were evaluated...
December 7, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27924741/health-and-health-related-indicators-in-slum-rural-and-urban-communities-a-comparative-analysis
#15
Blessing U Mberu, Tilahun Nigatu Haregu, Catherine Kyobutungi, Alex C Ezeh
BACKGROUND: It is generally assumed that urban slum residents have worse health status when compared with other urban populations, but better health status than their rural counterparts. This belief/assumption is often because of their physical proximity and assumed better access to health care services in urban areas. However, a few recent studies have cast doubt on this belief. Whether slum dwellers are better off, similar to, or worse off as compared with rural and other urban populations remain poorly understood as indicators for slum dwellers are generally hidden in urban averages...
2016: Global Health Action
https://www.readbyqxmd.com/read/27924614/gdf11-treatment-attenuates-the-recovery-of-skeletal-muscle-function-after-injury-in-older-rats
#16
Yu Zhou, Neel Sharma, David Dukes, Maria B Myzithras, Priyanka Gupta, Ashraf Khalil, Julius Kahn, Jennifer S Ahlberg, David B Hayes, Michael Franti, Tracy Criswell
Loss of skeletal muscle mass and function results in loss of mobility for elderly patients. Novel therapies that can protect and/or restore muscle function during aging would have profound effects on the quality of life for this population. Growth differentiation factor 11 (GDF11) has been proposed as a "youthful" circulating factor that can restore cardiac, neural, and skeletal muscle functions in aging animals. However, conflicting data has been recently published that casts doubt on these assertions. We used a complex rat model of skeletal muscle injury that physiologically mimics injuries seen in patients; to investigate the ability of GDF11 and to enhance skeletal muscle regeneration after injury in older rats...
December 6, 2016: AAPS Journal
https://www.readbyqxmd.com/read/27923219/nonoperative-versus-operative-treatment-of-displaced-ankle-fractures-in-diabetics
#17
Andrew J Lovy, James Dowdell, Aakash Keswani, Steven Koehler, Jaehon Kim, Steven Weinfeld, David Joseph
BACKGROUND: Diabetes is a risk factor for complications related to displaced ankle fractures. Limited literature exists comparing complication rates in nonoperative versus operative treatment of displaced ankle fractures in diabetics. No study has highlighted the natural history of nonoperative treatment of displaced ankle fractures in diabetics. METHODS: We retrospectively reviewed all adult ankle fractures from September 2011 through December 2014. Inclusion was limited to ambulatory adults (>18 years) with closed, displaced (widened mortise) ankle fractures with diabetes mellitus...
November 14, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27922127/variability-of-space-use-patterns-in-a-free-living-eusocial-rodent-ansell-s-mole-rat-indicates-age-based-rather-than-caste-polyethism
#18
Jan Šklíba, Matěj Lövy, Hynek Burda, Radim Šumbera
Eusocial species of African mole-rats live in groups cooperating on multiple tasks and employing division of labour. In captivity, individuals of the same group differ in cooperative contribution as well as in preference for a particular task. Both can be viewed as polyethism. However, little information is available from free-ranging mole-rats, which live in large burrow systems. We made an attempt to detect polyethism in the free-living Ansell's mole-rat (Fukomys anselli) as differences in individuals' space-use patterns...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27921018/comparison-of-the-protective-effects-of-erythropoietin-and-melatonin-on-renal-ischemia-reperfusion-injury
#19
Shokofeh Banaei, Nasser Ahmadiasl, Alireza Alihemmati
BACKGROUND: Renal ischemia-reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be the principal components involved in the pathophysiological tissue alterations observed during renal IR. OBJECTIVES: In this study, we compared the effects of melatonin (MEL) and erythropoietin (EPO), both known antioxidant and anti-inflammatory agents, on IR-induced renal injury in rats. MATERIALS AND METHODS: Wistar albino rats were unilaterally nephrectomized and then subjected to 45 minutes of renal pedicle occlusion followed by 24 hours of reperfusion...
July 2016: Trauma Monthly
https://www.readbyqxmd.com/read/27918290/nacre-mimetic-bulk-lamellar-composites-reinforced-with-high-aspect-ratio-glass-flakes
#20
Selen N Gurbuz Guner, Arcan F Dericioglu
Nacre-mimetic epoxy matrix composites reinforced with readily available micron-sized high aspect ratio C-glass flakes were fabricated by a relatively simple, single-step, scalable, time, cost and man-power effective processing strategy: hot-press assisted slip casting (HASC). HASC enables the fabrication of preferentially oriented two-dimensional inorganic reinforcement-polymer matrix bulk lamellar composites with a micro-scale structure resembling the brick-and-mortar architecture of nacre. By applying the micro-scale design guideline found in nacre and optimizing the relative volume fractions of the reinforcement and the matrix as well as by anchoring the brick-and-mortar architecture, and tailoring the interface between reinforcements and the matrix via silane coupling agents, strong, stiff and tough bio-inspired nacre-mimetic bulk composites were fabricated...
December 5, 2016: Bioinspiration & Biomimetics
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