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https://www.readbyqxmd.com/read/28227984/preliminary-study-on-the-automated-skull-fracture-detection-in-ct-images-using-black-hat-transform
#1
Ayumi Yamada, Atsushi Teramoto, Tomoko Otsuka, Kohei Kudo, Hirofumi Anno, Hiroshi Fujita, Ayumi Yamada, Atsushi Teramoto, Tomoko Otsuka, Kohei Kudo, Hirofumi Anno, Hiroshi Fujita, Tomoko Otsuka, Hiroshi Fujita, Ayumi Yamada, Kohei Kudo, Hirofumi Anno, Atsushi Teramoto
Linear skull fracture, following head trauma, may reach major blood vessels, such as the middle meningeal artery or sinus venosus, and may cause epidural hematoma. However, hematoma is likely to be missed in the initial interpretation because it spreads only gradually. In addition, the fracture lines that run along the scan slice plane are often missed during initial interpretation. In this study, we develop a novel method for automated detection of the linear skull fracture using head computed tomography (CT) images and conduct a basic evaluation using digital phantom and head phantom that enclose genuine human bones...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227983/3d-small-structure-detection-in-medical-image-using-texture-analysis
#2
Fei Gao, Min Zhang, Teresa Wu, Kevin M Bennett, Fei Gao, Min Zhang, Teresa Wu, Kevin M Bennett, Min Zhang, Teresa Wu, Fei Gao, Kevin M Bennett
Small structure segmentation from medical images is a challenging problem yet has important applications. Examples are labeling cell, lesion and glomeruli for disease diagnosis, just to name a few. Though extensive research has proposed various detectors for this type of problem, most are 2D detectors. Recently, we have developed a Hessian based 3D detector to segment small structures from medical images (e.g., MRI). In our detector, two 3D geometrical features: regional blobness and flatness, in conjunction with the intensity features are fully utilized to serve the segmentation purpose...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227959/localizing-seizure-onset-zone-by-convolutional-transfer-entropy-from-ieeg
#3
Kang Lin, Yueming Wang, Kedi Xu, Junming Zhu, Jianmin Zhang, Xiaoxiang Zheng, Kang Lin, Yueming Wang, Kedi Xu, Junming Zhu, Jianmin Zhang, Xiaoxiang Zheng, Xiaoxiang Zheng, Junming Zhu, Yueming Wang, Kedi Xu, Kang Lin, Jianmin Zhang
Automatic localization of the seizure onset zone (SOZ) is able to output an objective result and help clinical doctors greatly in epilepsy therapy. Transfer entropy is one of the most frequently used measures based on information theory to localize the SOZ. However, if only using transfer entropy to localize the SOZ, different results can be obtained during different periods, thus humans still need to identify which one is most reasonable. This paper proposes a new method to output only a few (e.g. 1 or 2) results along a long time slot...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227937/effects-of-tuning-conditions-on-near-field-of-mri-transmit-birdcage-coil-at-64-mhz
#4
Mikhail Kozlov, Elena Lucano, Leonardo M Angelone, Mikhail Kozlov, Elena Lucano, Leonardo M Angelone, Elena Lucano, Leonardo M Angelone, Mikhail Kozlov
This study investigates how the tuning conditions of a 64 MHz / 1.5 T radio frequency (RF) birdcage coil modeled with an RF circuit and 3D electromagnetic co-simulation affect the electric and magnetic near-field distribution. Four models were implemented with different tuning conditions and difference between numerical results and measurements was evaluated. The results show that the simulated near-field depends significantly on coil tuning conditions, especially in volumes close to the ASTM phantom walls...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227925/principal-component-analysis-can-decrease-neural-networks-performance-for-incipient-falls-detection-a-preliminary-study-with-hands-and-feet-accelerations
#5
Fiorenzo Artoni, Dario Martelli, Vito Monaco, Silvestre Micera, Fiorenzo Artoni, Dario Martelli, Vito Monaco, Silvestre Micera
Fall-related accidents constitute a major problem for elderly people and a burden to the health-care national system. It is therefore important to design devices (e.g., accelerometers) and machine learning algorithms able to recognize incipient falls as quickly and reliably as possible. Blind source separation (BSS) methods are often used as a preprocessing step before classification, however the effects of BSS on classification performance are not well understood. The aim of this work is to preliminarily characterize the effect that two methods, namely Principal and Independent Component Analysis (PCA and ICA) and their combined use have on the performance of a neural network in detecting incipient falls...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227912/a-hybrid-discrete-continuous-model-of-in-vitro-spheroid-tumor-growth-and-drug-response
#6
Giorgos Tzedakis, Evangelos Liapis, Eleftheria Tzamali, Giannis Zacharakis, Vangelis Sakkalis, Giorgos Tzedakis, Evangelos Liapis, Eleftheria Tzamali, Giannis Zacharakis, Vangelis Sakkalis, Giannis Zacharakis, Vangelis Sakkalis, Evangelos Liapis, Giorgos Tzedakis, Eleftheria Tzamali
Anti-cancer therapy efficacy in solid tumors mainly depends on drug transportation through the vasculature system and the extracellular matrix, on diffusion gradients and clonal heterogeneity within the tumor mass, as well as on the responses of the individual tumor cells to drugs and their interactions with each other and their local microenvironment. In this work, we develop a mathematical predictive model for tumor growth and drug response based on 3D spheroids experiments that possess several in vivo features of tumors and are considered better for drug screening...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227888/simulating-the-activation-contraction-and-movement-of-skeletal-muscles-using-the-bidomain-model
#7
A Lopez Rincon, C Cantu, R Soto, S Shimoda, A Lopez Rincon, C Cantu, R Soto, S Shimoda, A Lopez Rincon, R Soto, C Cantu, S Shimoda
A simulation of the muscle activation, contraction and movement is here presented. This system was developed based on the Bidomain mathematical model of the electrical propagation in muscles. This study shows an electrical stimuli input to a muscle and how this behave. The comparison between healthy subject and patient with muscle activation impairment is depicted, depending on whether the signal reaches a threshold. A 3D model of a bicep muscle and a forearm bone connected was constructed using OpenGL. This platform could be used for development of controllers for biomechatronic systems in future works...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227885/orthodontic-force-simulation-of-tooth-pdl-bone-complex-under-archwire-loading
#8
Xinwen Zhou, Zeyang Xia, Yangzhou Gan, Dongxia Zhang, Jing Xiong, Peng Fang, Guanglin Li, Qunfei Zhao, Xinwen Zhou, Zeyang Xia, Yangzhou Gan, Dongxia Zhang, Jing Xiong, Peng Fang, Guanglin Li, Qunfei Zhao, Zeyang Xia, Peng Fang, Xinwen Zhou, Dongxia Zhang, Yangzhou Gan, Guanglin Li, Jing Xiong, Qunfei Zhao
Orthodontic force simulation is very important for the guidance of clinical orthodontic treatment. Previous works were mainly conducted by directly loading the force on a single or a few teeth. However, in clinic, the orthodontic force is provided by loading orthodontic appliances, and there currently is no appropriate way to measure the force on the teeth provided by the loaded appliances. This study presents a method to simulate the orthodontic force of a whole Tooth-Periodontal Ligament-Bone Complex (TPBC) by directly loading the archwire to the dentition applying the finite element method...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227868/middle-and-inner-ear-modelling-from-microct-images-to-3d-reconstruction-and-coupling-of-models
#9
N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, A I Sakellarios, V Isailovic, D I Fotiadis, A Bibas, F Bohnke, G Ni, N Filipovic, G Rigas, N S Tachos
We present finite element (FE) modeling approaches of ear mechanics including 3-dimensional (3D) reconstruction of the human middle and inner ear. Specifically, we demonstrate a semi-automatic methodology for the 3D reconstruction of the inner ear structures, a FE harmonic response model of the middle ear to predict the stapes footplate frequency response, a 2D FE slice model of the cochlea for the coupled response at the micromechanical level for either acoustic or electrical excitation and a coupled FE middle ear model with a simplified cochlea box model to simulate the basilar membrane velocity in response to acoustic excitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227866/modelling-nutrient-transfer-based-on-3d-imaging-of-the-human-placental-microstructure
#10
S Perazzolo, R M Lewis, B G Sengers, S Perazzolo, R M Lewis, B G Sengers, B G Sengers, R M Lewis, S Perazzolo
Impaired transfer of nutrients from mother to fetus can affect pregnancy outcomes. The placenta has a complex microstructure, including the maternal intervillous space and fetal capillaries. Previous computational models of placental transfer either assumed a simplified idealized local geometry or were based on 2D imaging. In this study, we present a novel 3D computational model to assess the placental transfer of nutrients at the microscale in interaction with the maternal flow environment. A stack of confocal microscopy images of the placental terminal villi was collected and reconstructed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227864/automatic-segmentation-of-multimodal-brain-tumor-images-based-on-classification-of-super-voxels
#11
M Kadkhodaei, S Samavi, N Karimi, H Mohaghegh, S M R Soroushmehr, K Ward, A All, K Najarian, M Kadkhodaei, S Samavi, N Karimi, H Mohaghegh, S M R Soroushmehr, K Ward, A All, K Najarian, K Ward, S M R Soroushmehr, A All, S Samavi, M Kadkhodaei, H Mohaghegh, K Najarian, N Karimi
Despite the rapid growth in brain tumor segmentation approaches, there are still many challenges in this field. Automatic segmentation of brain images has a critical role in decreasing the burden of manual labeling and increasing robustness of brain tumor diagnosis. We consider segmentation of glioma tumors, which have a wide variation in size, shape and appearance properties. In this paper images are enhanced and normalized to same scale in a preprocessing step. The enhanced images are then segmented based on their intensities using 3D super-voxels...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227855/simultaneous-reconstruction-and-segmentation-with-the-mumford-shah-functional-for-electron-tomography
#12
Li Shen, Eric Todd Quinto, Shiqiang Wang, Ming Jiang, Li Shen, Eric Todd Quinto, Shiqiang Wang, Ming Jiang, Ming Jiang, Eric Todd Quinto, Shiqiang Wang, Li Shen
Electron micrography (EM) is an important method for determining the three-dimensional (3D) structure of macromolecular complexes and biological specimens. But there are several limitations such as poor signal-to-noise, limitation on range of tilt angles and sub-region subject to electron exposure, unintentional movements of the specimen, with EM systems that make the reconstruction procedure a severely ill-posed problem. A different choice of reconstruction method may lead to different results and create different additional artifacts in reconstructed images...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227854/3d-reconstruction-of-cochlea-using-optical-coherence-tomography
#13
Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Yuki Uranishi, Hiroshi Tamura, Tatsunori Sakamoto, Yosuke Tona, Tomohiro Kuroda, Kazuya Okamoto, Tuukka Karvonen
Recently, in vivo visualization of the cochlea and the smaller structures inside of it has been achieved by optical coherence tomography (OCT). This makes it possible to use OCT imaging for diagnosis of diseases such as Meniere's disease through measuring the degree of endolymphatic hydrops. To this end, we present a novel method for 3D segmentation of these cochlear OCT images that is based on superpixels and diffusion maps. The method takes as input grayscale volumetric OCT images and outputs a binary image with the segmented cochlea...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227853/fast-submicrometer-scale-imaging-of-whole-zebrafish-using-the-knife-edge-scanning-microscope
#14
Daniel E Miller, Raj S Shah, Wencong Zhang, Jaewook Yoo, Jaerock Kwon, David Mayerich, John Keyser, Louise C Abbott, Yoonsuck Choe, Daniel E Miller, Raj S Shah, Wencong Zhang, Jaewook Yoo, Jaerock Kwon, David Mayerich, John Keyser, Louise C Abbott, Yoonsuck Choe, Jaewook Yoo, Louise C Abbott, Wencong Zhang, John Keyser, Raj S Shah, Daniel E Miller, Jaerock Kwon, David Mayerich, Yoonsuck Choe
Advances in high-resolution 3D microscopy have enabled the investigation of subcellular microstructures in biological specimen. For a full understanding of the organism's structure and function, it is mandatory to obtain data from the whole animal, not just parts of it. In this paper, we present our work with the Knife-Edge Scanning Microscope (KESM) for imaging a Nissl-stained whole zebrafish larva. KESM combines a diamond microtome and line-scan imaging for simultaneous sectioning and imaging in 3D. We show that using the KESM, a zebrafish, less than 3 mm long and diameter less than 500 μm, can be imaged within 1 hour at a resolution of 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227836/exerciser-for-rehabilitation-of-the-arm-era-development-and-unique-features-of-a-3d-end-effector-robot
#15
Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Philippe-Olivier Provost, Dominic Letourneau, Maxime Dupuis, Marie-Helene Milot, Francois Michaud, Mathieu Hamel, Julien Bernier-Ouellet, Simon Briere
Stroke is one of the leading causes of disability worldwide. Consequently, many stroke survivors exhibit difficulties undergoing voluntary movement in their affected upper limb, compromising their functional performance and level of independence. To minimize the negative impact of stroke disabilities, exercises are recognized as a key element in post-stroke rehabilitation. In order to provide the practice of exercises in a uniform and controlled manner as well as increasing the efficiency of therapists' interventions, robotic training has been found, and continues to prove itself, as an innovative intervention for post-stroke rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227794/a-numerical-and-experimental-study-of-acoustic-micromixing-in-3d-microchannels-for-lab-on-a-chip-devices
#16
Susana O Catarino, Vania C Pinto, Paulo J Sousa, Rui Lima, Joao M Miranda, Graca Minas, Susana O Catarino, Vania C Pinto, Paulo J Sousa, Rui Lima, Joao M Miranda, Graca Minas, Joao M Miranda, Paulo J Sousa, Susana O Catarino, Rui Lima, Vania C Pinto, Graca Minas
This paper reports a numerical and experimental study of acoustic streaming and micromixing in polydimethylsiloxane microchannels. The mixing between two fluids flowing in microchannels was evaluated through the following conditions: (1) using a 28 μm thick β-poly(vinylidene fluoride) (β-PVDF) as a piezoelectric transducer actuated with a 24 Vpp and 40 MHz sinusoidal voltage; (2) using different flow rates. The results suggest that the mixing length increases as the flow rate increases and that the acoustic streaming phenomenon leads to a reduction on the mixing length...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227792/an-innovative-therapy-for-peri-implantitis-based-on-radio-frequency-electric-current-numerical-simulation-results-and-clinical-evidence
#17
G Cosoli, L Scalise, G Tricarico, E P Tomasini, G Cerri, G Cosoli, L Scalise, G Tricarico, E P Tomasini, G Cerri, G Cosoli, E P Tomasini, G Cerri, G Tricarico, L Scalise
Peri-implantitis is a severe inflammatory pathology that affects soit and hard tissues surrounding dental implants. Nowadays, only prevention is effective to contrast peri-implantitis, but, in recent years, there is the clinical evidence of the efficiency of a therapy based on the application of radio frequency electric current, reporting that 81% of the cases (66 implants, 46 patients) were successfully treated. The aim of this paper is to present the therapy mechanism, exploring the distribution of the electric currents in normal and pathologic tissues...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227775/3d-anatomical-reconstruction-of-human-cardiac-conduction-system-and-simulation-of-bundle-branch-block-after-tavi-procedure
#18
Andrew J Atkinson, Sanjay R Kharche, Michael G Bateman, Paul A Iaizzo, Halina Dobrzynski, Andrew J Atkinson, Sanjay R Kharche, Michael G Bateman, Paul A Iaizzo, Halina Dobrzynski, Andrew J Atkinson, Paul A Iaizzo, Halina Dobrzynski, Sanjay R Kharche, Michael G Bateman
The cardiac conduction system (CCS) is responsible for the initiation and propagation of action potentials through the heart ensuring efficient pumping of blood. Understanding the anatomy of the CCS and its relationship with other major cardiac components is important to help understand arrhythmias and how certain procedures may increase the incidence of arrhythmias developing. We sectioned a whole human heart and performed Masson's trichrome histology in order to identify the components of the CCS. The histology images were used to construct a 3D anatomical model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227773/whole-heart-modeling-spatiotemporal-dynamics-of-electrical-wave-conduction-and-propagation
#19
Hui Yang, Yun Chen, Fabio M Leonelli, Hui Yang, Yun Chen, Fabio M Leonelli, Hui Yang, Fabio M Leonelli, Yun Chen
Cardiac electrical activities are varying in both space and time. Human heart consists of a fractal network of muscle cells, Purkinje fibers, arteries and veins. Whole-heart modeling of electrical wave conduction and propagation involves a greater level of complexity. Our previous work developed a computer model of the anatomically realistic heart and simulated the electrical conduction with the use of cellular automata. However, simplistic assumptions and rules limit its ability to provide an accurate approximation of real-world dynamics on the complex heart surface, due to sensitive dependence of nonlinear dynamical systems on initial conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227716/heart-activity-monitoring-using-3d-hologram-based-on-smartphone
#20
Tharoeun Thap, Heewon Chung, Jinseok Lee, Tharoeun Thap, Heewon Chung, Jinseok Lee, Tharoeun Thap, Jinseok Lee, Heewon Chung
In this paper, we used smartphone to obtained pulsatile signal from a fingertip by illuminating the skin tissue using flashlight and with an on-board camera to record the change of the light intensity reflected from the tissue. The pulsatile signal is produced by analyzing average green component values of the frames taken by the camera and the heart rate is estimated in real time by detecting the pulse peaks. Based on each instant obtained heartbeat, we design a heart animation that beats according to each interval of the heartbeat...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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