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https://www.readbyqxmd.com/read/29778038/hierarchically-three-dimensional-3d-nanotubular-sea-urchin-shaped-iron-oxide-and-its-application-in-heavy-metal-removal-and-solar-induced-photocatalytic-degradation
#1
Soon Chang Lee, Yesul Jeong, Youn Jung Kim, Hyeran Kim, Hyun Uk Lee, Young-Chul Lee, Sang Moon Lee, Hae Jin Kim, Ha-Rim An, Myoung Gyu Ha, Go-Woon Lee, Young-Seak Lee, Gaehang Lee
In this study, hierarchically three-dimensional (3D) nanotubular sea urchin-shaped iron oxide nanostructures (3D-Fe2 O3 ) were synthesized by a facile and rapid ultrasound irradiation method. Additives, templates, inert gas atmosphere, pH regulation, and other complicated procedures were not required. Dense 3D-Fe2 O3 with a relatively large Brunauer-Emmett-Teller (BET) surface area of 129.4 m2 /g was synthesized within 23 min, and the BET surface area was further improved to 282.7 m2 /g by a post heat-treatment process...
April 23, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29778016/multiscale-reconstruction-of-a-synthetic-biomimetic-micro-niche-for-enhancing-and-monitoring-the-differentiation-of-stem-cells
#2
Rui Li, Jinming Li, Jianbin Xu, Dexter Siu Hong Wong, Xiaoyu Chen, Weihao Yuan, Liming Bian
Stem cells reside in a three-dimensional (3D) niche microenvironment, which provides specific cues, including cell-matrix interactions and soluble factors, that are essential to the differentiation of stem cells in vivo. Herein we demonstrate a general approach to the synthetic reconstruction of 3D biomimetic niche environment of stem cells by the multiscale combination of macroscopic porous hydrogels and a nanoscale upconversion nanoparticles (UCNP)-based nanocomplex. The porous biopolymeric hydrogels emulate the spongy bone microstructure and provide 3D environment conducive to the differentiation of seeded stem cells...
May 4, 2018: Biomaterials
https://www.readbyqxmd.com/read/29777982/documentation-and-analysis-of-traumatic-injuries-in-clinical-forensic-medicine-involving-structured-light-three-dimensional-surface-scanning-versus-photography
#3
Awatif Shamata, Tim Thompson
Non-contact three-dimensional (3D) surface scanning has been applied in forensic medicine and has been shown to mitigate shortcoming of traditional documentation methods. The aim of this paper is to assess the efficiency of structured light 3D surface scanning in recording traumatic injuries of live cases in clinical forensic medicine. The work was conducted in Medico-Legal Centre in Benghazi, Libya. A structured light 3D surface scanner and ordinary digital camera with close-up lens were used to record the injuries and to have 3D and two-dimensional (2D) documents of the same traumas...
May 10, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29777971/symmetric-supercapacitor-sulphurized-graphene-and-ionic-liquid
#4
Jasmin S Shaikh, Navajsharif S Shaikh, Rohini Kharade, Sonali A Beknalkar, Jyoti V Patil, Mahesh P Suryawanshi, Pongsakorn Kanjanaboos, Chang Kook Hong, Jin Hyeok Kim, Pramod S Patil
Symmetric supercapacitor is advanced over simple supercapacitor device due to their stability over a large potential window and high energy density. Graphene is a desired candidate for supercapacitor application since it has a high surface area, good electronic conductivity and high electro chemical stability. There is a pragmatic use of ionic liquid electrolyte for supercapacitor due to its stability over a large potential window, good ionic conductivity and eco-friendly nature. For high performance supercapacitor, the interaction between ionic liquid electrolyte and graphene are crucial for better charge transportation...
May 11, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29777961/non-viral-delivery-of-an-optogenetic-tool-into-cells-with-self-healing-hydrogel
#5
Fu-Yu Hsieh, Hao-Wei Han, Xiao-Ru Chen, Chii-Shen Yang, Yen Wei, Shan-Hui Hsu
Optogenetics offers unique, temporally precise control of neural activity in genetically targeted specific neurons that express light-sensitive opsin molecules. Three-dimensional (3D) delivery of optogenetics can be realized by co-injection of bacteriorhodopsin (HEBR) plasmid with a chitosan-based self-healing hydrogel with strong shear-thinning properties. The HEBR protein shows photoelectrical properties and can be used as an optical switch for cell activation. We optimize the shear force generated during the process of injection (∼100 Pa), which is transient because of the self-healing nature of the hydrogel...
May 9, 2018: Biomaterials
https://www.readbyqxmd.com/read/29777941/characterization-of-the-binding-of-a-novel-antitumor-drug-ibrutinib-with-human-serum-albumin-insights-from-spectroscopic-calorimetric-and-docking-studies
#6
Bin Tang, Peixiao Tang, Jiawei He, Hongqin Yang, Hui Li
Ibrutinib (IBR) is a novel Bruton's tyrosine kinase inhibitor and shows good efficacy for several B-cell malignancies. In the current study, the molecular mechanism of the interaction between IBR and the transport protein human serum albumin (HSA) was ascertained by spectroscopic, calorimetric, and docking studies. Detailed investigations on affinity parameter, binding model, conformational change, and site selectivity were implemented by receptor-based and ligand-based analysis. An unusual fluorescence co-quenching (mutual quenching) was observed in the binding of IBR to HSA, followed by a static mechanism...
May 16, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29777889/endovascular-management-of-a-ruptured-basilar-perforator-artery-aneurysm-associated-with-a-pontine-arteriovenous-malformation-a-case-report-and-review-of-the-literature
#7
Joseph Lockwood, Tyler Scullen, Mansour Mathkour, Ascher Kaufmann, Ricky Medel, Aaron S Dumont, Peter S Amenta
BACKGROUND: Arteriovenous malformation (AVM)-associated aneurysms are common, being reported in 15% of cases. In regards to ruptured posterior fossa AVMs, associated aneurysms are present in 48% of cases and are the etiology of the bleed in 37%. We present a 75 year-old female who presented with a subarachnoid hemorrhage (SAH) secondary to a ruptured aneurysm arising from a flow-related basilar perforator artery feeder of an anterior pontine AVM. We report the successful treatment of the aneurysm with coil embolization...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29777859/three-dimensional-model-of-the-female-perineum-and-pelvic-floor-muscles
#8
Géraldine Giraudet, Laurent Patrouix, Christian Fontaine, Xavier Demondion, Michel Cosson, Chrystèle Rubod
OBJECTIVE: The anatomy of the perineum and the pelvic diaphragm of woman is complex. A numerical complete three-dimensional (3D) model of every muscle of the woman pelvis doesn't exist. The pathophysiology of genital prolapse is still debated. Knowledge of anatomy is essential to better understand its mechanisms. The aim of this research was to build a complete three-dimensional model of the female perineum and pelvic floor muscles. STUDY DESIGN: To model the pelvic muscles we reconstructed them in three dimensions from tracing a magnetic resonance imaging (MRI) of a female pelvis from a cadaver...
May 16, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29777757/stem-cell-based-retina-models
#9
Kevin Achberger, Jasmin C Haderspeck, Alexander Kleger, Stefan Liebau
From the early days of cell biological research, the eye-especially the retina-has evoked broad interest among scientists. The retina has since been thoroughly investigated and numerous models have been exploited to shed light on its development, morphology, and function. Apart from various animal models and human clinical and anatomical research, stem cell-based models of animal and human cells of origin have entered the field, especially during the last decade. Despite the observation that the retina of different species comprises endogenous stem cells, most stem cell-related research in the human retina is now based on pluripotent stem cell models...
May 16, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29777354/randomized-study-of-the-influence-of-two-dimensional-versus-three-dimensional-imaging-using-a-novel-3d-head-mounted-display-hms-3000mt-on-performance-of-laparoscopic-inguinal-hernia-repair
#10
M Patrzyk, M Klee, T Stefaniak, C D Heidecke, K Beyer
BACKGROUND: 3D laparoscopy has proven to be superior to the 2D approach in experimental settings. The aim of the present study was to investigate the influence of 3D laparoscopy using a novel head-mounted display on the performance of defined steps within a laparoscopic inguinal hernia repair. This effect was investigated both in laparoscopically advanced surgeons and in beginners. METHODS: Patients suffering from symptomatic inguinal hernia were randomly assigned to laparoscopic hernia repair using either a head-mounted 3D display or a conventional 2D laparoscopic approach...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777252/noninvasively-evaluating-the-grading-and-idh1-mutation-status-of-diffuse-gliomas-by-three-dimensional-pseudo-continuous-arterial-spin-labeling-and-diffusion-weighted-imaging
#11
Tingting Liu, Guang Cheng, Xiaowei Kang, Yibin Xi, Yuanqiang Zhu, Kai Wang, Chao Sun, Jing Ye, Ping Li, Hong Yin
PURPOSE: To noninvasively evaluate the value of three-dimensional pseudo-continuous arterial spin labeling (3D pCASL) and diffusion-weighted imaging (DWI) in diffuse gliomas grading as well as isocitrate dehydrogenase (IDH) 1 mutation status. METHODS: Fifty-six patients with pathologically confirmed diffuse gliomas with preoperative 3D pCASL and DWI were enrolled in this study. The Student's t test and Mann-Whitney U test were used to evaluate differences in parameters of DWI and 3D pCASL between low and high grade as well as between mutant and wild-type IDH1 diffuse gliomas; receiver operator characteristic (ROC) analysis was used to assess the diagnostic performance...
May 18, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29777174/how-does-blood-regulate-cerebral-temperatures-during-hypothermia
#12
Stephen Blowers, Ian Marshall, Michael Thrippleton, Peter Andrews, Bridget Harris, Iain Bethune, Prashant Valluri
Macro-modeling of cerebral blood flow can help determine the impact of thermal intervention during instances of head trauma to mitigate tissue damage. This work presents a bioheat model using a 3D fluid-porous domain coupled with intersecting 1D arterial and venous vessel trees. This combined vascular porous (VaPor) model resolves both cerebral blood flow and energy equations, including heat generated by metabolism, using vasculature extracted from MRI data and is extended using a tree generation algorithm...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29777156/high-quality-3d-photonics-using-nano-imprint-lithography-of-fast-sol-gel-materials
#13
Ofer Bar-On, Philipp Brenner, Tobias Siegle, Raz Gvishi, Heinz Kalt, Uli Lemmer, Jacob Scheuer
A method for the realization of low-loss integrated optical components is proposed and demonstrated. This approach is simple, fast, inexpensive, scalable for mass production, and compatible with both 2D and 3D geometries. The process is based on a novel dual-step soft nano imprint lithography process for producing devices with smooth surfaces, combined with fast sol-gel technology providing highly transparent materials. As a concrete example, this approach is demonstrated on a micro ring resonator made by direct laser writing (DLW) to achieve a quality factor improvement from one hundred thousand to more than 3 million...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29777123/synthesis-fungicidal-activity-structure-activity-relationships-sars-and-density-functional-theory-dft-studies-of-novel-strobilurin-analogues-containing-arylpyrazole-rings
#14
Yuanyuan Liu, Kunzhi Lv, Yi Li, Qiuli Nan, Jinyuan Xu
A series of novel strobilurin analogues (1a-1f, 2a-2e, 3a-3e) containing arylpyrazole rings were synthesized and characterized by NMR spectroscopy. The structures of 1f, 2b and 3b were also determined by single crystal X-ray diffraction analysis. These analogues were collected together with other twenty-eight similar compounds 4a-4f, 5a-5h, 6a-6h and 7a-7f from our previous studies, for in vitro bioassays and thorough structure-activity relationships (SARs) studies. Most compounds exhibited excellent-to-good fungicidal activity against Rhizoctonia solani, especially 5c, 7a, 6c, and 3b with 98...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776831/3d-brachytherapy-for-cervical-cancer-new-optimization-ways
#15
I Fumagalli, C Haie-Méder, C Chargari
Brachytherapy has known major improvements in recent decades. It represents an essential component of local treatment of cervix cancers. One major breakthrough was the advent of 3D imaging for image-guided brachytherapy. Doses could be prescribed to volumes. This allows better delineation and coverage of target volumes, as well as organs at risk (bladder, rectum, sigmoid) protection. Local recurrences have been consequently reduced and survival has been improved. In addition, improvement and development of new applicators have facilitated the delivery of interstitial treatments...
May 15, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29776675/risk-factors-for-near-miss-events-and-safety-incidents-in-pediatric-radiation-therapy
#16
Nimrah Baig, Jiangxia Wang, Shereef Elnahal, Todd McNutt, Jean Wright, Theodore DeWeese, Stephanie Terezakis
BACKGROUND AND PURPOSE: Factors contributing to safety- or quality-related incidents (e.g. variances) in children are unknown. We identified clinical and RT treatment variables associated with risk for variances in a pediatric cohort. MATERIALS AND METHODS: Using our institution's incident learning system, 81 patients age ≤21 years old who experienced variances were compared to 191 pediatric patients without variances. Clinical and RT treatment variables were evaluated as potential predictors for variances using univariate and multivariate analyses...
May 15, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29776544/two-photon-fluorescent-probe-for-detection-of-nitroreductase-and-hypoxia-specific-microenvironment-of-cancer-stem-cell
#17
Yajing Liu, Wei Liu, Hongjuan Li, Weixiao Yan, Xinjian Yang, Dandan Liu, Shuxiang Wang, Jinchao Zhang
Hypoxia plays a crucial role in cancer progression, and it has great significance for monitoring hypoxic level in biosystems. Cancer stem cells (CSCs) represent a small population of tumour cells that regard as the key to seed tumours. The survival of CSCs depend on the tumour microenvironment, which is distinct region has the hypoxic property. Therefore, the detection of the hypoxic CSC niche plays a pivotal role in the destructing the 'soil' of CSCs, and eliminating CSCs population. Numerous one-photon excited fluorescent probes have been developed to indicate the hypoxic status in tumours through the detection of nitroreductase (NTR) level...
September 18, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29776397/the-conserved-p-arg108-residue-in-s1pr2-dfnb68-is-fundamental-for-proper-hearing-evidence-from-a-consanguineous-iranian-family
#18
Michaela A H Hofrichter, Majid Mojarad, Julia Doll, Clemens Grimm, Atiye Eslahi, Neda Sadat Hosseini, Mohsen Rajati, Tobias Müller, Marcus Dittrich, Reza Maroofian, Thomas Haaf, Barbara Vona
BACKGROUND: Genetic heterogeneity and consanguineous marriages make recessive inherited hearing loss in Iran the second most common genetic disorder. Only two reported pathogenic variants (c.323G>C, p.Arg108Pro and c.419A>G, p.Tyr140Cys) in the S1PR2 gene have previously been linked to autosomal recessive hearing loss (DFNB68) in two Pakistani families. We describe a segregating novel homozygous c.323G>A, p.Arg108Gln pathogenic variant in S1PR2 that was identified in four affected individuals from a consanguineous five generation Iranian family...
May 18, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29776156/realizations-of-highly-heterogeneous-collagen-networks-via-stochastic-reconstruction-for-micromechanical-analysis-of-tumor-cell-invasion
#19
Hanqing Nan, Long Liang, Guo Chen, Liyu Liu, Ruchuan Liu, Yang Jiao
Three-dimensional (3D) collective cell migration in a collagen-based extracellular matrix (ECM) is among one of the most significant topics in developmental biology, cancer progression, tissue regeneration, and immune response. Recent studies have suggested that collagen-fiber mediated force transmission in cellularized ECM plays an important role in stress homeostasis and regulation of collective cellular behaviors. Motivated by the recent in vitro observation that oriented collagen can significantly enhance the penetration of migrating breast cancer cells into dense Matrigel which mimics the intravasation process in vivo [Han et al...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776070/analysis-and-optimization-of-population-annealing
#20
Christopher Amey, Jonathan Machta
Population annealing is an easily parallelizable sequential Monte Carlo algorithm that is well suited for simulating the equilibrium properties of systems with rough free-energy landscapes. In this work we seek to understand and improve the performance of population annealing. We derive several useful relations between quantities that describe the performance of population annealing and use these relations to suggest methods to optimize the algorithm. These optimization methods were tested by performing large-scale simulations of the three-dimensional (3D) Edwards-Anderson (Ising) spin glass and measuring several observables...
March 2018: Physical Review. E
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