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Pregnancy and migrain

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https://www.readbyqxmd.com/read/27902848/topiramate-in-migraine-prevention-a-2016-perspective
#1
Stephen D Silberstein
BACKGROUND: In evidence-based guidelines published in 2000, topiramate was a third-tier migraine preventive with no scientific evidence of efficacy; recommendation for its use reflected consensus opinion and clinical experience. Its neurostabilizing activity, coupled with its favorable weight profile, made topiramate an attractive alternative to other migraine preventives that caused weight gain. When guidelines for migraine prevention in episodic migraine were published in 2012, topiramate was included as a first-line option based on double-blind, randomized controlled trials involving nearly 3000 patients...
November 30, 2016: Headache
https://www.readbyqxmd.com/read/27870430/sex-related-influences-in-migraine
#2
REVIEW
Jelena M Pavlovic, Didem Akcali, Hayrunnisa Bolay, Carolyn Bernstein, Nasim Maleki
Migraine is a common neurological disorder with significantly higher incidence and prevalence in women than men. The presentation of the disease in women is modulated by changes in sex hormones from adolescence to pregnancy and menopause. Yet, the effect of sex influences has often been neglected in both basic and clinical and in clinical management of the disease. In this review, evidence from epidemiological, clinical, animal, and neuroimaging studies on the significance of the sex-related influences in migraine is presented, and the unmet needs in each area are discussed...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27818772/effectiveness-and-safety-of-an-extended-release-tablet-of-sodium-valproate-for-the-prophylactic-treatment-of-migraine-postmarketing-surveillance-in-japan
#3
Takao Takeshima, Norihiro Suzuki, Yasuhiko Matsumori, Naoki Shimmoto, Yuji Kurihara, Ryoji Gunji, Fumihiko Sakai
BACKGROUND: Sodium valproate is a standard drug for first-line prophylactic treatment of migraine. However, little information is available of its use in Japanese patients. AIM: To evaluate the effectiveness and safety of an extended-release tablet of sodium valproate in the prophylactic treatment for Japanese patients with migraine by postmarketing surveillance. METHODS: This was a prospective, multicenter and non-interventional observation study in routine clinical practice...
July 2016: Neurology and Clinical Neuroscience
https://www.readbyqxmd.com/read/27807736/-analgesic-drugs-during-pregnancy
#4
S Hultzsch, C Schaefer
Some important limitations must be taken into consideration for analgesic therapy during pregnancy. Paracetamol is the agent of choice for mild to moderate pain in any stage of pregnancy. Ibuprofen is the non-steroidal anti-inflammatory drug (NSAID) of choice; however, these substances are contraindicated after 28 weeks of gestation due to the increasing risk of premature closure of the ductus arteriosus and impairment of fetal kidney function. Even opioids can be used for severe pain but peripartum administration can lead to neonatal respiratory depression and adaptation disorders and long-term therapy up to the end of pregnancy can lead to neonatal withdrawal symptoms...
November 2, 2016: Der Schmerz
https://www.readbyqxmd.com/read/27789184/a-limited-survey-based-uncontrolled-follow-up-study-of-children-born-after-ooplasmic-transplantation-in-a-single-centre
#5
Serena H Chen, Claudia Pascale, Maria Jackson, Mary Ann Szvetecz, Jacques Cohen
Experimental ooplasmic transplantation from donor to recipient oocyte took place between 1996 and 2001 at Saint Barnabas Medical Center, USA. Indication for 33 patients was repeated implantation failure. Thirteen couples had 17 babies. One patient delivered twins from mixed ooplasmic and donor egg embryos. A limited survey-based follow-up study on the children is reported: 12 out of 13 parents completed a questionnaire on pregnancy, birth, health, academic performance and disclosure. Parents of a quadruplet did not participate...
October 24, 2016: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/27698740/neurological-teratogenic-effects-of-antiepileptic-drugs-during-pregnancy
#6
Qingmei Nie, Baohua Su, Jianping Wei
Epilepsy is one of the few neurologic disorders that requires a constant treatment during pregnancy. Epilepsy affects 0.3-0.8% of pregnant women. Prescription of antiepileptic drugs (AEDs) to pregnant women with epilepsy requires monitoring and maintaining a balance between limiting seizures and decreasing fetal exposure to the potential teratogenic effects. AEDs are also commonly used for psychiatric disorders, pain disorders, and migraines. The types of malformations that can result in fetuses exposed to AEDs include minor anomalies, major congenital malformations, intrauterine growth retardation, cognitive dysfunction, low IQ, microcephaly, and infant mortality...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27625061/longitudinal-changes-in-neurodevelopmental-outcomes-between-18-and-36%C3%A2-months-in-children-with-prenatal-triptan-exposure-findings-from-the-norwegian-mother-and-child-cohort-study
#7
Mollie E Wood, Jean A Frazier, Hedvig M E Nordeng, Kate L Lapane
OBJECTIVE: This study sought to determine whether changes in neurodevelopmental outcomes between 18 and 36 months of age were associated with prenatal exposure to triptan medications, a class of 5-HT receptor agonists used in the treatment of migraine. METHOD: Using data from the Norwegian Mother and Child Cohort Study, a prospective birth cohort that includes nearly 40% of all pregnancies in Norway from 1999 to 2008, we identified 50 469 mother-child dyads who met inclusion criteria and were present for at least one follow-up assessment at 18 or 36 months postpartum...
September 13, 2016: BMJ Open
https://www.readbyqxmd.com/read/27624901/use-of-antimigraine-medications-and-information-needs-during-pregnancy-and-breastfeeding-a-cross-sectional-study-among-401-norwegian-women
#8
Siri Amundsen, Torunn G Øvrebø, Netta Marie S Amble, Anne Christine Poole, Hedvig Nordeng
PURPOSE: Migraine is highly prevalent among women of fertile age. The main objectives of this study were to describe the prevalence and patterns of use of antimigraine medications during pregnancy and breastfeeding and to identify maternal and migraine-related factors associated with medication use during pregnancy. METHODS: The study is a cross-sectional internet-based survey among pregnant women and new mothers with migraine conducted in Norway from October 1, 2013 to February 1, 2014...
December 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27574186/dtb-select-9-september-2016
#9
(no author information available yet)
Assessing the risk: high vs. low antibiotic prescribing rates for RTIs ● RCOG guidance on nausea and vomiting in pregnancy ● Medical devices-USA vs. EU ● More on opioids for RLS ● Acupuncture for migraine prevention ● NICE guidance on oral health in care homes ● Liraglutide and cardiovascular outcomes in type 2 diabetes ● How useful is the study you are reading or writing?
September 2016: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/27562782/imaging-of-headache-in-pregnancy
#10
REVIEW
Maryna Skliut, Dara G Jamieson
Pregnant women are most likely to have primary headaches, such as migraine and tension-type headaches, which can be diagnosed and treated without brain imaging. Primary headaches may even start de novo during pregnancy, especially in the first few months. However, when the headache occurs late in pregnancy or in the peripartum period, secondary causes of headaches need to be considered and evaluated by brain and/or vascular imaging, generally using magnetic resonance techniques. There is considerable overlap between the cerebrovascular complications of pregnancy, including preeclampsia/eclampsia, posterior reversible encephalopathy syndrome (PRES), reversible cerebral vasoconstriction syndrome (RCVS), and both hemorrhagic and ischemic strokes; although, their imaging may be distinctive...
October 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27548360/ten-challenges-in-contraception
#11
Audrey Binette, Kerry Howatt, Ashley Waddington, Robert L Reid
Despite the introduction of promising products into the contraceptive market, the rate of unintended pregnancies remains high. Women with underlying medical conditions should have access to safe and effective contraceptive methods for various reasons, including the potential deleterious effect of the disease on the pregnancy or the effect of the pregnancy on the disease process. Healthcare providers are often confronted with cases in which contraception counseling is problematic due to controversial evidence and persistent myths...
August 22, 2016: Journal of Women's Health
https://www.readbyqxmd.com/read/27411842/a-nationwide-evaluation-of-spontaneous-coronary-artery-dissection-in-pregnancy-and-the-puerperium
#12
Majed S Faden, Natalie Bottega, Alice Benjamin, Richard N Brown
OBJECTIVE: Spontaneous coronary artery dissection (SCAD) is a rare and potentially lethal cause of myocardial infarction (MI). The purpose of our study was to estimate the prevalence and maternal outcomes of pregnancies complicated by SCAD. MATERIALS AND METHODS: A population-based cohort study on all births identified in the Healthcare Cost and Utilization Project from 2008 to 2012. Disease prevalence was calculated and logistic regression was used to estimate the adjusted odds ratio (aOR) for risk factors and different maternal complications...
July 13, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27364828/dtb-select-7-july-2016
#13
(no author information available yet)
MHRA: avoid live vaccines in immunosuppressed patients ● Topical NSAIDs for musculoskeletal pain in adults ● Adherence to pregnancy prevention measures during isotretinoin treatment ● Impact of the NHS Health Check programme ● Ibuprofen: first choice for migraine in young people? ● Neuropsychiatric safety of ▼ varenicline and bupropion ● Effects of anticholinergic medication in cognitively normal older adults ● New NICE guidance for controlled drugs.
July 2016: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/27154242/ongoing-pharmacological-management-of-chronic-pain-in-pregnancy
#14
REVIEW
Bengt Källén, Margareta Reis
The article discusses possible effects of the use of analgesics during pregnancy. It summarizes the pertinent literature and reports some previously unpublished data from the Swedish Medical Birth Register. Most likely the use of analgesics does not cause spontaneous abortion. Only small malformation risk increases are seen after the use of opioids and perhaps non-steroid anti-inflammatory drug (NSAID) use. If possible, the latter should be avoided during the first trimester. If exposure has occurred there is no reason to consider an interruption of the pregnancy...
June 2016: Drugs
https://www.readbyqxmd.com/read/27059507/combined-hormonal-contraception-use-in-reproductive-age-women-with-contraindications-to-estrogen-use
#15
Julianne R Lauring, Erik B Lehman, Timothy A Deimling, Richard S Legro, Cynthia H Chuang
BACKGROUND: The Centers for Disease Control and Prevention's US Medical Eligibility Criteria for Contraceptive Use recommends that combined hormonal contraceptives (ie, birth control pills, contraceptive patch, vaginal ring) should be avoided in women with specific medical conditions because of the increased risk of cardiovascular events associated with estrogen use. Whether women with category 3 (theoretical or proven risk usually outweigh the advantages) or category 4 (unacceptable health risk) contraindications are appropriately avoiding estrogen-containing combined hormonal contraceptives is unknown...
September 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27054719/screening-for-unruptured-intracranial-aneurysms-in-autosomal-dominant-polycystic-kidney-disease-a-survey-of-420-nephrologists
#16
Adrien Flahault, Denis Trystram, Marie Fouchard, Bertrand Knebelmann, François Nataf, Dominique Joly
BACKGROUND: Despite a high prevalence of intracranial aneurysm (ICA) in autosomal dominant polycystic kidney disease (ADPKD), rupture events are rare. The current recommendations for ICA screening are based on expert opinions and studies with low levels of evidence. OBJECTIVES: The aim of our study was to describe the attitudes of practicing nephrologists in Europe towards screening for ICA using magnetic resonance angiography (MRA). METHODS: We conducted a web-based survey among 1315 European French-speaking nephrologists and nephrology residents...
2016: PloS One
https://www.readbyqxmd.com/read/27050859/recommendations-for-the-treatment-of-migraine-attacks-a-brazilian-consensus
#17
Carlos Alberto Bordini, Célia Roesler, Deusvenir de Souza Carvalho, Djacir Dantas P Macedo, Élcio Piovesan, Eliana Meire Melhado, Fabiola Dach, Fernando Kowacs, Hilton Mariano da Silva Júnior, Jano Alves de Souza, Jayme Antunes Maciel, João José de Freitas de Carvalho, José Geraldo Speciali, Liselotte Menke Barea, Luiz Paulo Queiroz, Marcelo Cedrinho Ciciarelli, Marcelo Moraes Valença, Márcia Maria Ferreira Lima, Maurice Borges Vincent
In this article, a group of experts in headache management of the Brazilian Headache Society developed through a consensus strategic measurements to treat a migraine attack in both the child and the adult. Particular emphasis was laid on the treatment of migraine in women, including at pregnancy, lactation and perimenstrual period.
March 2016: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/27017029/migraine-and-hormones
#18
REVIEW
Ann Pakalnis
This article discusses the role that hormones play in adolescent girls and young women with headaches, which are very common in adolescent girls, in particular, migraine. In many cases, migraine onset may occur shortly around the time of menarche, prevalence of recurrent migraine in this population approaches 15%, and typically the symptoms continue through adulthood. Hormonal changes associated with puberty and the menstrual cycle may significantly influence migraine in young women. This article reviews the following topics: management of menstrually related headaches, changes in ovarian hormones and their relationship to migraine, and oral contraceptives and pregnancy effects on migraine...
February 2016: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/27016264/association-of-migraine-headaches-with-suicidal-ideation-among-pregnant-women-in-lima-peru
#19
Lauren E Friedman, Bizu Gelaye, Marta B Rondon, Sixto E Sanchez, B Lee Peterlin, Michelle A Williams
BACKGROUND: Suicide is a leading cause of maternal death globally, and suicide prevalence rates have been shown to be increased in those with migraine. No previous study has examined the association between migraine and suicidal ideation during pregnancy. OBJECTIVE: To examine the association between migraine and suicidal ideation among a cohort of pregnant women. METHODS: A cross-sectional study was conducted among 3372 pregnant women attending prenatal care clinics in Lima, Peru...
April 2016: Headache
https://www.readbyqxmd.com/read/27012659/reversible-cerebral-vasoconstriction-syndrome-associated-with-interferon-beta-1a-use-for-multiple-sclerosis
#20
Tamara Strohm, Burhan Chaudhry, Mary A Willis, Steven Shook
BACKGROUND: Reversible cerebral vasoconstriction syndrome (RCVS) has been associated with multiple medications, cocaine, pregnancy, migraine, and other conditions. OBJECTIVES: RCVS associated with interferon beta use has never before been described. METHODS: We describe the case of a 20-year-old female who developed acute onset severe headache and was found to have subarachnoid hemorrhage 2 months after initiating Rebif (Interferon beta-1a) for multiple sclerosis (MS)...
March 24, 2016: Multiple Sclerosis: Clinical and Laboratory Research
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