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https://www.readbyqxmd.com/read/28815601/antimicrobial-synergism-and-cytotoxic-properties-of-citrus-limon-l-piper-nigrum-l-and-melaleuca-alternifolia-maiden-and-betche-cheel-essential-oils
#1
Miloš M Nikolić, Katarina K Jovanović, Tatjana Lj Marković, Dejan Lj Marković, Nevenka N Gligorijević, Siniša S Radulović, Marina Kostić, Jasmina M Glamočlija, Marina D Soković
OBJECTIVES: The chemical composition, antimicrobial and synergistic effect, and cytotoxic activity of Citrus limon (lemon), Piper nigrum (green pepper) and Melaleuca alternifoila (tea tree) essential oils (EOs) were investigated. METHODS: Chemical analyses of essential oils were tested by GC-FID and GC-MS spectroscopy. The antimicrobial activity assay was conducted using microdilution method against several oral bacteria and Candida spp. originating from the humans with oral disorders...
August 17, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28813782/urea-cycle-pathway-targeted-therapeutic-action-of-naringin-against-ammonium-chloride-induced-hyperammonemic-rats
#2
Arumugam Ramakrishnan, Natesan Vijayakumar
Ammonia is a well-known neurotoxin that causes liver disease and urea cycle disorder. Excessive ammonia content in the blood leads to hyperammonemic condition and affects both excitatory and inhibitory neurotransmission including brain edema and coma. Naringin, a plant bioflavonoid present in various citrus fruits and mainly extracted from the grape fruit. This study was designed to assess the protective effect of naringin on ammonium chloride (NH4Cl) induced hyperammonemic rats. Experimental hyperammonemia was induced by intraperitoneal injections (i...
August 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28810519/the-beneficial-role-of-naringin-a-citrus-bioflavonoid-against-oxidative-stress-induced-neurobehavioral-disorders-and-cognitive-dysfunction-in-rodents-a-systematic-review-and-meta-analysis
#3
REVIEW
Gollapalle Lakshminarayanashastry Viswanatha, H Shylaja, Yogananda Moolemath
OBJECTIVES: Naringin is a bioflavonoid, very abundantly found in citrus species. In literature, naringin has been scientifically well documented for its beneficial effects in various neurological disorders. In this systematic review and meta-analysis, we have made an attempt to correlate the protective role of naringin against oxidative stress-induced neurological disorders in rodents. METHODS: The systematic search was performed using electronic databases; the search was mainly focused on the role of naringin in oxidative stress-induced neuropathological conditions in rodents...
August 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28806973/protective-effects-of-orange-citrus-sinensis-l-peel-aqueous-extract-and-hesperidin-on-oxidative-stress-and-peptic-ulcer-induced-by-alcohol-in-rat
#4
Slimen Selmi, Kais Rtibi, Dhekra Grami, Hichem Sebai, Lamjed Marzouki
BACKGROUND: Massive alcohol drinking can lead to gastric ulcer. In the present study we investigated the gastroprotective effect of Citrus sinensis peel aqueous extract (CSPE) and Hesperidin (H) in ethanol (EtOH) induced oxidative stress and peptic ulcer in rats. METHODS: Seventy adult male Wistar rats were divided into seven groups of 10 each: control, EtOH (4 g/kg b.w.), EtOH + various doses of CSPE (100, 200 and 400 mg/kg, b.w.), EtOH + Hesperidin (50 mg/kg, p...
August 14, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28805916/the-reduction-of-starch-in-finishing-diets-supplemented-with-oil-does-not-prevent-the-accumulation-of-trans-10-18-1-in-lamb-meat
#5
M Costa, S P Alves, A Francisco, J Almeida, C M Alfaia, S V Martins, J A M Prates, J Santos-Silva, O Doran, R J B Bessa
The experiment was conducted to test the hypothesis that the replacement of cereal with low-starch feed ingredients in lambs' finishing diets supplemented with oils could prevent the accumulation of -10-18:1 in meat. Forty lambs were fed 1 of 4 diets supplemented with soybean oil (5.9%) and fish oil (1%) for 6 wk before slaughter. The control (CON) diet contained 43% barley, and in the other diets, barley was completely replaced by dehydrated citrus pulp (DCP), dehydrated sugar beet pulp (DBP), or soybean hulls (SH)...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805834/profiles-of-free-and-bound-phenolics-extracted-from-citrus-fruits-and-their-roles-in-biological-systems-content-and-antioxidant-anti-diabetic-and-anti-hypertensive-properties
#6
Muhammad H Alu'datt, Taha Rababah, Mohammad N Alhamad, Majdi A Al-Mahasneh, Khalil Ereifej, Ghazi Al-Karaki, Mohammed Al-Duais, Juan E Andrade, Carole C Tranchant, Stan Kubow, Kawther A Ghozlan
This study of selected plants of the Rutaceae family was carried out to investigate their phenolic content, antioxidant activity, and the in vitro inhibitory potential of extracted phenolics towards enzymes relevant for hyperglycemia and hypertension. The phenolic content, antioxidant activity and phenolic extract-mediated inhibitory activities for α-glucosidase and α-amylase were evaluated by spectrophotometry. The content of individual phenolics and the angiotensin I-converting enzyme (ACE) inhibitory activity of the phenolic extracts were evaluated by LC/MS-MS and RP-HPLC methods, respectively...
August 14, 2017: Food & Function
https://www.readbyqxmd.com/read/28802186/a-l-type-lectin-gene-is-involved-in-the-response-to-hormonal-treatment-and-water-deficit-in-volkamer-lemon
#7
Dayse Drielly Sousa Santana Vieira, Giovanni Emiliani, Paola Bartolini, Alessandra Podda, Mauro Centritto, François Luro, Renata Del Carratore, Raphaël Morillon, Abelmon Gesteira, Biancaelena Maserti
Combination of biotic and abiotic stress is a major challenge for crop and fruit production. Thus, identification of genes involved in cross-response to abiotic and biotic stress is of great importance for breeding superior genotypes. Lectins are glycan-binding proteins with a functions in the developmental processes as well as in the response to biotic and abiotic stress. In this work, a lectin like gene, namely ClLectin1, was characterized in Volkamer lemon and its expression was studied in plants exposed to either water stress, hormonal elicitors (JA, SA, ABA) or wounding to understand whether this gene may have a function in the response to multiple stress combination...
August 1, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28802068/dietary-citrate-and-plasma-ionized-calcium-implications-for-platelet-donors
#8
Stefanie Haynes, Elda Hickson, Jeanne Linden, Patricia St Pierre, Paula Ducharme, Paula Sulmasy, Linda Welch, Yong Zhao, Mindy Greene, Michelle Vauthrin, Robert Weinstein
BACKGROUND: Platelet donors receive 40 mmol or more of IV citrate anion during donation. When plasma ionized calcium ([Ca(2+) ]) falls by ∼20%, half of the donors report symptoms of hypocalcemic toxicity. Citrus juices contain clinically relevant amounts of citrate anion. We asked whether citrus juice can lower [Ca(2+) ] thus potentially contributing to hypocalcemic toxicity. METHOD: Six volunteers were given 20.4 mmol of citrate anion as grapefruit juice or orange juice...
August 12, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28797279/huanglongbing-impairs-the-rhizosphere-to-rhizoplane-enrichment-process-of-the-citrus-root-associated-microbiome
#9
Yunzeng Zhang, Jin Xu, Nadia Riera, Tao Jin, Jinyun Li, Nian Wang
BACKGROUND: Roots are the primary site for plant-microbe interactions. Among the three root-associated layers (i.e., rhizosphere, rhizoplane, and endorhiza), the rhizoplane is a key component serving a critical gating role that controls microbial entry into plant roots. The microbial communities colonizing the three layers are believed to be gradually enriched from the bulk soil inoculum. However, it is unknown how this enrichment process, particularly the rhizosphere to rhizoplane step, is affected by biotic stresses, such as disease...
August 10, 2017: Microbiome
https://www.readbyqxmd.com/read/28782634/a-new-allergen-family-involved-in-pollen-food-associated-syndrome-snakin-gibberellin-regulated-proteins
#10
Hélène Sénéchal, Jiří Šantrůček, Magdalena Melčová, Petr Svoboda, Jarmila Zídková, Denis Charpin, Laurence Guilloux, Youcef Shahali, Marie-Ange Selva, Rémy Couderc, Tomoyasu Aizawa, Pascal Poncet
At least two pollen food associated syndromes were described with cypress pollen allergy involving peach and citrus. Snakin/gibberellin regulated proteins are described herein to be the cross-reactive allergens between Cupressus sempervirens pollen and fruit/vegetables.
August 3, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28781084/crystal-structure-and-regulation-of-the-citrus-pol-iii-repressor-maf1-by-auxin-and-phosphorylation
#11
Adriana Santos Soprano, Priscila Oliveira de Giuseppe, Hugo Massayoshi Shimo, Tatiani Brenelli Lima, Fernanda Aparecida Heleno Batista, Germanna Lima Righetto, José Geraldo de Carvalho Pereira, Daniela Campos Granato, Andrey Fabricio Ziem Nascimento, Fabio Cesar Gozzo, Paulo Sérgio Lopes de Oliveira, Ana Carolina Migliorini Figueira, Juliana Helena Costa Smetana, Adriana Franco Paes Leme, Mario Tyago Murakami, Celso Eduardo Benedetti
MAF1 is the main RNA polymerase (Pol) III repressor that controls cell growth in eukaryotes. The Citrus ortholog, CsMAF1, was shown to restrict cell growth in citrus canker disease but its role in plant development and disease is still unclear. We solved the crystal structure of the globular core of CsMAF1, which reveals additional structural elements compared with the previously available structure of hMAF1, and explored the dynamics of its flexible regions not present in the structure. CsMAF1 accumulated in the nucleolus upon leaf excision, and this translocation was inhibited by auxin and by mutation of the PKA phosphorylation site, S45, to aspartate...
July 24, 2017: Structure
https://www.readbyqxmd.com/read/28777044/ectopic-expression-of-xylella-fastidiosa-rpff-conferring-production-of-diffusible-signal-factor-in-transgenic-tobacco-and-citrus-alters-pathogen-behavior-and-reduces-disease-severity
#12
Raquel Caserta, Reinaldo Rodrigues Souza-Neto, Marco Aurelio Takita, Steven Lindow, Alessandra De Souza
The pathogenicity of Xylella fastidiosa is associated with its ability to colonize the xylem of host plants. Expression of genes contributing to xylem colonization are suppressed, while those necessary for insect vector acquisition are increased, with increasing concentrations of diffusible signal factor (DSF) whose production is dependent on RpfF. We previously demonstrated that transgenic citrus plants ectopically expressing rpfF from a citrus strain of X. fastidiosa subsp. pauca exhibited less susceptibility to Xanthomonas citri subsp...
August 4, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/28774297/citrus-lemon-essential-oil-chemical-composition-antioxidant-and-antimicrobial-activities-with-its-preservative-effect-against-listeria-monocytogenes-inoculated-in-minced-beef-meat
#13
Anis Ben Hsouna, Nihed Ben Halima, Slim Smaoui, Naceur Hamdi
BACKGROUND: Lemon (Citrus limon) is a flowing plant belonging to the Rutaceae family. Citrus plants constitute one of the main valuable sources of essential oil used in foods and medicinal purposes. METHODS: In this study, we assessed chemical composition, antioxidant and antimicrobial activities of C. limon essential oil (ClEO) with its preservative effect against Listeria monocytogenes inoculated in minced beef meat. Gas chromatography/mass spectrometry (GC-MS) was used to identify the major components of the obtained ClEO...
August 3, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28769912/xanthomonas-citri-minc-oscillates-from-pole-to-pole-to-ensure-proper-cell-division-and-shape
#14
André S G Lorenzoni, Giordanni C Dantas, Tessa Bergsma, Henrique Ferreira, Dirk-Jan Scheffers
Xanthomonas citri (Xac) is the causal agent of citrus canker, a disease that affects citrus crops and causes economic impact worldwide. To further characterize cell division in this plant pathogen, we investigated the role of the protein MinC in cell division, chromosome segregation, and peptidoglycan incorporation by deleting the gene minC using allele exchange. Xac with minC deleted exhibited the classic Δmin phenotype observed in other bacteria deleted for min components: minicells and short filamentation...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28764092/starch-digestibility-and-predicted-glycemic-index-in-the-bread-fortified-with-pomelo-citrus-maxima-fruit-segments
#15
S K Reshmi, M L Sudha, M N Shashirekha
The aim of this study was to evaluate the starch digestibility and predicted glycemic index in breads incorporated with pomelo fruit (Citrus maxima) segments. Volume of the white and brown breads supplemented with pomelo fresh segments increased, while the crumb firmness decreased. Bread with 20% fresh and 5% dry pomelo segments were sensorily acceptable. Bioactive components such as phenolics, flavonoids, naringin and carotenoids were retained to a greater extent in bread containing dry pomelo segments. The pomelo incorporated bread had higher levels of resistant starch fractions (3...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28764055/anthocyanin-biosynthesis-and-accumulation-in-blood-oranges-during-postharvest-storage-at-different-low-temperatures
#16
Lourdes Carmona, Berta Alquézar, Viviani V Marques, Leandro Peña
Blood oranges require low temperature for anthocyanin production. We have investigated the activation of anthocyanin biosynthesis and accumulation in the pulp of Moro blood and Pera blond oranges (Citrus sinensis L. Osbeck) stored at either 4 or 9°C after harvesting. Both temperatures stimulated anthocyanin accumulation in blood but not in blond oranges. Nonetheless, blood orange fruits stored at 9°C reached a darker purple coloration, higher anthocyanin contents and enhanced upregulation of genes from the flavonoid pathway in the pulp and juice than those kept at 4°C...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28763749/protective-effects-of-ethanolic-peel-and-pulp-extracts-of-citrus-macroptera-fruit-against-isoproterenol-induced-myocardial-infarction-in-rats
#17
Sudip Paul, Sagarika Das, E M Tanvir, Md Sakib Hossen, Moumoni Saha, Rizwana Afroz, Md Aminul Islam, Md Sabir Hossain, Siew Hua Gan, Md Ibrahim Khalil
Increases in the incidence of cardiovascular disease (CVD) have aroused strong interest in identifying antioxidants from natural sources for use in preventive medicine. Citrus macroptera (C. macroptera), commonly known as "Satkara", is an important herbal and medicinal plant reputed for its antioxidant, nutritious and therapeutic uses. The aim of the present study was to investigate the cardio-protective effects of ethanol extracts of C. macroptera peel and pulp against isoproterenol (ISO)-induced myocardial infarction (MI) in rats...
July 29, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28761874/underwater-shockwave-pretreatment-process-to-improve-the-scent-of-extracted-citrus-junos-tanaka-yuzu-juice
#18
Eisuke Kuraya, Akiko Touyama, Shina Nakada, Osamu Higa, Shigeru Itoh
Citrus junos Tanaka (yuzu) has a strong characteristic aroma and thus its juice is used in various Japanese foods. Herein, we evaluate the volatile compounds in yuzu juice to investigate whether underwater shockwave pretreatment affects its scent. A shockwave pretreatment at increased discharge and energy of 3.5 kV and 4.9 kJ, respectively, increased the content of aroma-active compounds. Moreover, the underwater shockwave pretreatment afforded an approximate tenfold increase in the scent intensity of yuzu juice cultivated in Rikuzentakata...
2017: International journal of food science
https://www.readbyqxmd.com/read/28760553/genome-wide-identification-of-sweet-orange-citrus-sinensis-metal-tolerance-proteins-and-analysis-of-their-expression-patterns-under-zinc-manganese-copper-and-cadmium-toxicity
#19
Xing-Zheng Fu, Ya-Hua Tong, Xue Zhou, Li-Li Ling, Chang-Pin Chun, Li Cao, Ming Zeng, Liang-Zhi Peng
Plant metal tolerance proteins (MTPs) play important roles in heavy metal homeostasis; however, related information in citrus plants is limited. Citrus genome sequencing and assembly have enabled us to perform a systematic analysis of the MTP gene family. We identified 12 MTP genes in sweet orange, which we have named as CitMTP1 and CitMTP3 to CitMTP12 based on their sequence similarity to Arabidopsis thaliana MTPs. The CitMTPs were predicted to encode proteins of 864 to 2556 amino acids in length that included 4 to 6 putative transmembrane domains (TMDs)...
July 28, 2017: Gene
https://www.readbyqxmd.com/read/28758988/beneficial-effects-of-galectin-3-blockade-in-vascular-and-aortic-valve-alterations-in-an-experimental-pressure-overload-model
#20
Jaime Ibarrola, Ernesto Martínez-Martínez, J Rafael Sádaba, Vanessa Arrieta, Amaia García-Peña, Virginia Álvarez, Amaya Fernández-Celis, Alicia Gainza, Patrick Rossignol, Victoria Cachofeiro Ramos, Natalia López-Andrés
Galectin-3 (Gal-3) is involved in cardiovascular fibrosis and aortic valve (AV) calcification. We hypothesized that Gal-3 pharmacological inhibition with modified citrus pectin (MCP) could reduce aortic and AV remodeling in normotensive rats with pressure overload (PO). Six weeks after aortic constriction, vascular Gal-3 expression was up-regulated in male Wistar rats. Gal-3 overexpression was accompanied by an increase in the aortic media layer thickness, enhanced total collagen, and augmented expression of fibrotic mediators...
July 31, 2017: International Journal of Molecular Sciences
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