Valentina Faihs, Viktoria Schmalhofer, Claudia Kugler, Rebekka K Bent, Katharina A Scherf, Barbara Lexhaller, Charlotte G Mortz, Carsten Bindslev-Jensen, Tilo Biedermann, Per S Skov, Bernadette Eberlein, Knut Brockow
Wheat allergy dependent on augmentation factors (WALDA) is the most common gluten allergy in adults. IgE-mediated sensitizations are directed towards ω5-gliadin but also to other wheat allergens. The value of the different in vitro cellular tests, namely the basophil activation test (BAT) and the active (aBHRA) and passive basophil histamine-release assays (pBHRA), in the detection of sensitization profiles beyond ω5-gliadin has not been compared. Therefore, 13 patients with challenge-confirmed, ω5-gliadin-positive WALDA and 11 healthy controls were enrolled...
March 22, 2024: International Journal of Molecular Sciences