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Duplex Kidney

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https://www.readbyqxmd.com/read/29324920/technetium-99m-dimercaptosuccinic-acid-renal-scintigraphy-can-guide-clinical-management-in-congenital-hydronephrosis
#1
Biljana Bazić-Đorović, Marija Radulović, Marija Šišić, Ljiljana Jauković, Sanja Dugonjić, Dragan Pucar, Zoran Janković, Slobodanka Beatović, Milica Janković, Zoran Krstić, Boris Ajdinović
OBJECTIVE: The purpose of this study was to evaluate damage of the kidney with technetium-99m-dimercaptosuccinic acid (99mTc-DMSA) scintigraphy in children with congenital hydronephrosis (CH) and the influence of other postnatal associated diagnoses on abnormal 99mTc-DMSA findings. SUBJECTS AND METHODS: 99mTc-DMSA scintigraphy in 54 children (17 girls and 37 boys), aged from 2 months to 5 years (median 11 months) with 66 congenital hydronephrotic renal units (RU) (42 unilateral hydronephrosis-29 boys and 13 girls; 12 bilateral hydronephrosis-8 boys and 4 girls) was performed...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29290905/duplex-collecting-system-in-a-pelvic-kidney-an-unusual-combination
#2
Francesca Giorlando, Chiara Recaldini, Anna Leonardi, Edoardo Macchi, Carlo Fugazzola
Pelvic kidney is a relatively common renal malformation as well as duplex kidney; however, the unilateral coexistence of these abnormalities is not frequently found. We present a case of a young woman with a history of hypertension in whom a pelvic and dysmorphic left kidney was discovered during ultrasound examination performed for the study of the renal arteries. Magnetic resonance imaging and computed tomography imaging revealed a duplex pelvic kidney. This combination is very rare; we have not found a similar case reported in the literature...
December 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29224026/heminephrectomy-in-adults-a-systematic-review-with-cumulative-analysis
#3
Keiran Clement, Jane Hendry, Francis X Keeley, Omar M Aboumarzouk
INTRODUCTION: Duplex collecting system of the kidney is a relatively common abnormality, with the majority of symptomatic cases discovered in childhood. Treatment is commonly a heminephrectomy of the affected moiety. We aimed to conduct a systematic review of the literature to provide the best available evidence for heminephrectomy for duplex kidneys in the adult population. MATERIALS AND METHODS: A literature search was conducted in September 2017 with no limitations being placed on language, region, date or publication type...
December 8, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29203188/congenital-segmental-megaureter-in-an-ectopic-kidney
#4
A Khanna, R S Mavuduru, G S Bora, S K Devana, A K Mandal
We describe the imaging findings of a 19 year female who presented with recurrent urinary tract infections and pain abdomen which was diagnosed to be due to a left sided focal segmental megaureter with a calculus. The highlights of the case are functioning moiety with no other associated anomalies like VUR, Duplex system etc.
December 1, 2017: Urology
https://www.readbyqxmd.com/read/29201520/transurethral-incision-of-ureteroceles-in-paediatric-age-group
#5
Hemanshi Shah, Charu Tiwari, Neha Sisodiya Shenoy, Pankaj Dwivedi, Suraj Gandhi
Objective: Ureteroceles are a great clinical challenge because of variations in anatomy and clinical presentations. We present our experience with primary transurethral incision of ureteroceles in children. Material and methods: Data of thirteen children managed for ureterocele from 2009 to 2016 was retrospectively analyzed with respect to age, sex, clinical presentation and symptomatology, type and localization of ureterocele, investigations, surgical management and follow-up...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29186176/analysis-of-dna-topology-of-ebv-minichromosomes-in-hek-293-cells
#6
Alicia Castán, Vanessa Fernández-Calleja, Pablo Hernández, Dora B Krimer, Jorge B Schvartzman, María-José Fernández-Nestosa
Simian Virus 40 (SV40) and Epstein-Barr Virus (EBV) are frequently used as model systems to study DNA replication. Their genomes are both circular duplex DNAs organized in a single replicon where replication initiates at a precise site upon binding of a specific protein: the large tumor (T) antigen for SV40 and the Epstein-Barr Nuclear Antigen 1 (EBNA-1) for EBV. Despite the abundant information available on the genetics and biochemistry of the replication process in these systems, little is known about the changes in DNA topology that take place as molecules are transfected into eukaryotic cells, assembled into chromatin and bind initiator proteins to start replication...
2017: PloS One
https://www.readbyqxmd.com/read/29135146/-laparoscopic-heminephrureterectomy-for-duplex-kidney-in-children
#7
I M Kagantsov, V V Sizonov, V I Dubrov, S G Bon-Darenko, N R Akramov, O S Shmyrov, G I Kuzovleva, N V Markov, D E Sablin, R V Surov, A V Pirogov, A A Logval
INTRODUCTION: Duplication of the upper urinary tract is one of the most common congenital urological anomalies. In patients with critically decreased or lost function of one of the renal segments, heminephrureterectomy is usually the treatment of choice. Until recently, this was an open surgery; in cases of complete removal of the ureter, an additional incision in the iliac region was required. Currently, heminephrureterectomy is increasingly performed laparoscopically. We report the experience in laparoscopic heminephrureterectomy (LHNUE) in 10 clinics in Russia and Belarus...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29037562/dandy-walker-syndrome-with-duplex-kidney-abnormalities-in-trisomy-18-a-rare-case-report
#8
Tun-Jun Wang, Yi-Ying Li, Wan-Ju Wu, Chi-Kang Lin, Chun-Kai Wang, Chen-Yu Wang, Kwei-Shuai Hwang, Her-Young Su
OBJECTIVE: Trisomy 18 is one of the major numerical chromosomal disorders. The incidence of trisomy 18 is approximately one in 6000 live births. Dandy-Walker malformation (DWM) is the most common congenital malformation of the cerebellum, with an incidence of about one in 5000 live births. The incidence of trisomy 18 associated with DWM is rare and long-term survival rate is very low. CASE REPORT: A case involving a 39-year-old pregnant female with a case of trisomy 18 associated with DWM...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29027269/partial-nephrectomy-for-small-children-robot-assisted-versus-open-surgery
#9
Quentin Ballouhey, Aurélien Binet, Pauline Clermidi, Karim Braik, Thierry Villemagne, Jérôme Cros, Hubert Lardy, Laurent Fourcade
OBJECTIVES: To compare the outcomes of robot-assisted heminephrectomy for duplex kidney in children with those of open heminephrectomy. METHODS: The present retrospective multicentric analysis reviewed the records of robot-assisted versus open heminephrectomy carried out for duplex kidney in children from 2007 to 2014. Demographic data, weight, surgical time, hospital stay, complications and outcome were recorded. Follow up was based on a clinical review, renal sonography and dimercaptosuccinic acid renal scintigraphy...
October 13, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28958477/duplex-scan-and-histologic-assessment-of-acute-renal-injury-in-a-kidney-kidney-crosstalk-swine-experimental-model
#10
Anna Paula W Baptista Sincos, Angela Mazzeo, Igor Rafael Sincos, Felipe Coelho Neto, Nelson Wolosker, Ricardo Aun, Katia R M Leite, Vitoria Penido de Paula, Oskar G Kaufmann
OBJECTIVE: The objective of this study was to identify the effect of two left renal vasculature occlusion strategies on the duplex ultrasound-assessed rheology and histology of the contralateral kidney. METHODS: Pigs were randomly assigned to one of two groups: left renal artery-only clamping (A group, n = 8) or left renal artery and vein clamping (AV group, n = 9). Bilateral renal parenchymal biopsy specimens were taken every 10 minutes for 90 minutes. Duplex ultrasound resistive index (RI) and pulsatility index (PI) were measured...
September 25, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28943272/clinical-outcomes-of-the-upper-urinary-tract-after-ureteral-clipping-for-the-treatment-of-low-or-non-functioning-renal-moieties
#11
Roberto Iglesias Lopes, Nicolas Fernandez, Martin A Koyle, Joana Dos Santos, Jaime Perez, Rodrigo Romao, Armando J Lorenzo
PURPOSE: A growing body of evidence suggest it is safe to ligate the ureter of poorly functioning renal moieties during renal transplantation. Herein, we present clinical outcomes and data on hydronephrosis progression in pediatric cases associated with ectopic ureters and obstructive ureteroceles. MATERIAL AND METHODS: Prospective data collection on 35 consecutive patients (23 female, 12 male) who underwent ureteral clipping between 02/2011 and 08/2016. Patients were divided in four groups [I: duplex system (DS) with ectopic ureter (45...
September 21, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28918072/development-of-a-duplex-semi-nested-pcr-assay-for-detection-of-classical-goose-parvovirus-and-novel-goose-parvovirus-related-virus-in-sick-or-dead-ducks-with-short-beak-and-dwarfism-syndrome
#12
Pengfei Li, Ruihua Zhang, Junhao Chen, Dapeng Sun, Jingjing Lan, Shaoli Lin, Shasha Song, Zhijing Xie, Shijin Jiang
Duck short beak and dwarfism syndrome (SBDS) is an emerging infectious disease caused by a novel goose parvovirus-related virus (NGPV) in China. Until now, it remains uncertain whether the Cherry Valley ducks and mule ducks with SBDS are co-infected with classical goose parvovirus (GPV) and NGPV. In this study, a duplex semi-nested PCR assay with high specificity and sensitivity was developed for detection of the two viruses. Using the duplex PCR assay, NGPV was tested positive in all the 15 duck flocks with SBDS, whereas classical GPV was not detected in all the 133 sick and dead ducks collected from East China...
November 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28887264/toe-pressures-are-superior-to-duplex-parameters-in-predicting-wound-healing-following-toe-and-foot-amputations
#13
Patrick A Stone, Alexis Glomski, Stephanie N Thompson, Elliott Adams
BACKGROUND: No criteria, including preamputation vascular diagnostic thresholds, have been established to reliably predict healing versus nonhealing following minor lower extremity amputations. Thus, the goal of our study was to identify clinical factors, including noninvasive vascular laboratory measures, associated with wound healing following toe, forefoot, and midfoot amputations. METHODS: We retrospectively examined records of patients receiving elective toe, forefoot, or midfoot amputation at our institution over a 5-year span (2010-2015)...
January 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28833353/assessment-of-an-extended-interval-fondaparinux-dosing-regimen-for-venous-thromboembolism-prophylaxis-in-critically-ill-patients-with-severe-renal-dysfunction-using-antifactor-xa-levels
#14
Krista A Wahby, Lauren K Riley, Steven D Tennenberg
OBJECTIVE: Pharmacologic options for venous thromboembolism (VTE) prophylaxis are often limited in critically ill patients due to thrombocytopenia and multisystem organ dysfunction. Fondaparinux offers potential advantages in the critically ill; however, it is currently contraindicated in severe renal dysfunction (SRD). We evaluated anti-factor Xa levels in critically ill patients with SRD who were receiving an extended interval dosing regimen of fondaparinux for VTE prophylaxis. METHODS: A prospective, single-arm, interventional study was conducted at two academic hospitals of the Detroit Medical Center...
October 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28830149/mutagenicity-of-ochratoxin-a-role-for-a-carbon-linked-c8-deoxyguanosine-adduct
#15
REVIEW
Richard A Manderville, Stacey D Wetmore
Ochratoxin A (OTA) is a fungal toxin that is considered to be a potent kidney carcinogen in rodent models. The toxin produces double strand breaks and has a propensity for deletions, single-base substitutions, and insertions. The toxin reacts covalently with DNA to afford a C8-2'-deoxyguanosine carbon-linked adduct (OT-dG) as the major lesion in animal tissues. Incorporation of model C-linked C8-aryl-dG adducts into the G3 site of the NarI sequence demonstrates a tendency to induce base substitutions and deletion mutations in primer extension assays using model polymerases...
August 23, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28761593/case-series-transplantation-of-kidneys-from-donors-with-renal-artery-aneurysm
#16
Mahmoud Alameddine, Zhobin Moghadamyeghaneh, Giselle Guerra, Mahmoud Morsi, Mohammed Osman, V J Chia, George W Burke, Linda Chen, Rodrigo Vianna, Ian Zheng, Javier González, Gaetano Ciancio
INTRODUCTION: With the present disparity between organ availability and recipient demands, we reported our experience in transplanting kidneys with renal artery aneurysm after back-table reconstruction. METHODS: Four patients were identified. The repair consisted of excision of the aneurysm with ostial closure, and for one of the cases, an ovarian vein patch was used. We reviewed the safety and outcomes of this procedure. All donors were asymptomatic before surgery and were diagnosed incidentally during living donor evaluation...
July 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28749272/ketamine-medetomidine-and-ketamine-medetomidine-midazolam-anesthesia-in-captive-cheetahs-acinonyx-jubatus-comparison-of-blood-pressure-and-kidney-blood-flow
#17
Julia Stagegaard, Arne Hørlyck, Helle B Hydeskov, Mads F Bertelsen
Six clinically healthy captive cheetahs ( Acinonyx jubatus ) were anesthetized twice using two different drug combinations to investigate if blood pressure and kidney blood flow are affected by medetomidine dosage. Protocol KM (2.0 mg/kg ketamine and 0.05 mg/kg medetomidine) was compared with protocol KMM (2.0 mg/kg ketamine, 0.02 mg/kg medetomidine, and 0.1 mg/kg midazolam). Heart rate (HR), respiratory rate (RR), body temperature, end-tidal carbon dioxide pressure (ETCO2), and anesthetic depth were monitored every 10 min...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28724605/heterozygous-loss-of-function-mutation-in-odd-skipped-related-1-osr1-is-associated-with-vesico-ureteric-reflux-duplex-systems-and-hydronephrosis
#18
Marie-Lyne Fillion, Jasmine El Andalousi, Fatima Tokhmafshan, Vasikar Murugapoopathy, Christine L Watt, Inga J Murawski, John-Paul Capolicchio, Mohamed El-Sherbiny, Roman Jednak, Indra Rani Gupta
Osr1 is a transcriptional repressor that plays critical roles in maintaining the mesenchymal stem cell population within the developing kidney. Here, we report that newborn pups with a heterozygous null mutation in Osr1 exhibit a 21% incidence of vesico-ureteric reflux and have hydronephrosis and urinary tract duplications. Newborn pups have a short intravesical ureter resulting in a less competent uretero-vesical junction which arises from a delay in urinary tract development. We describe a new domain of Osr1 expression in the ureteral mesenchyme and within the developing bladder in the mouse...
July 19, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28699016/position-related-renal-perfusion-disturbances-as-a-possible-underestimated-mechanism-in-patients-with-resistant-hypertension-a-case-vignette
#19
Jan Schiefer, Holger Amthauer, Philipp Genseke, Peter R Mertens, Christos Chatzikyrkou
PURPOSE: In patients with resistant hypertension and large blood pressure fluctuations, the role of orthostatic hypertension, associated with position-dependent renal perfusion disturbances, has not been investigated in detail yet. METHODS: In this regard, four patients from our outpatient clinic were investigated by the use of 24-h ambulatory blood pressure monitoring (ABPM), active standing test, renal duplex sonography and Tc99m-mercaptoacetyltriglycine [MAG3] renal scintigraphy in supine and upright position...
October 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28689200/optimal-medical-management-reduces-risk-of-disease-progression-and-ischemic-events-in-asymptomatic-carotid-stenosis-patients-a-long-term-follow-up-study
#20
Zubair Shah, Reza Masoomi, Rashmi Thapa, Mashhood Wani, John Chen, Buddhadeb Dawn, Marilyn Rymer, Kamal Gupta
BACKGROUND AND PURPOSE: To assess the effect of optimal medical management including atherosclerotic risk factor control on ischemic stroke (IS), transient ischemic attack (TIA), carotid revascularization (CRV), and progression of severity of carotid stenosis (PSCS) in patients with asymptomatic carotid artery stenosis (ACAS). METHODS: We conducted a retrospective analysis of patients with ACAS (who had at least 3 serial carotid duplex ultrasounds) for incidence of IS, TIA, and PSCS...
2017: Cerebrovascular Diseases
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