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Alessandra P Sabarense, Gabriella O Lima, Lívia M L Silva, Marcos Borato Viana
OBJECTIVE: To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast the initial years with the final years. METHODS: Deaths were identified by active surveillance of children absent to scheduled appointments in Blood Bank Clinical Centers (Hemominas). Clinical and epidemiological data came from death certificates, neonatal screening database, medical records, and family interviews. RESULTS: Between 1998 and 2012, 3,617,919 children were screened and 2,591 had sickle cell disease (1:1,400)...
May 2015: Jornal de Pediatria
Liang-pu Xu, Hai-long Huang, Yan Wang, Lin Zheng, Lin-shuo Wang, Jin-bang Xu, Xin-xin Huang, Yuan Lin
OBJECTIVE: To investigate the gene prevalence and spectrum of alpha- and beta-thalassemia in Fujian province. METHODS: A total of 11 234 of neonatal cord blood samples were collected for a prevalence study of alpha- and beta-thalassemia. All subjects included in this study were registered in 9 cities of Fujian province. A complete blood count and high performance liquid chromatography (HPLC) were performed in all samples, with microcytosis (MCV≤ 79 f1 and MCH≤ 27 pg) or HPLC positive cases further studied by DNA analysis...
August 2013: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
Fabrizio Romano, Roberta Gelmini, Roberto Caprotti, Alessia Andreotti, Marcello Guaglio, Chiara Franzoni, Franco Uggeri, Massimo Saviano
BACKGROUND: Laparoscopic splenectomy (LS) is considered the gold standard for the treatment of hematologic disease of the spleen. Intraoperative bleeding is the main complication and main cause of conversion during LS. In this paper, we present our experience with 112 LS procedures, comparing two different techniques and instruments for spleen dissection and hilar vascular control. METHODS: We have performed a total of 112 LS procedures in 9 years in two affiliated university hospitals...
December 2007: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Fabrizio Romano, Roberto Caprotti, Claudio Franciosi, Sergio De Fina, Giovanni Colombo, Paola Sartori, Franco Uggeri
BACKGROUND: Laparoscopic splenectomy (LS) is becoming the gold standard for the treatment of hematological disease in children. Intraoperative bleeding is the main complication and main cause of conversion during LS. We present the use of the LigaSure Vessel Sealing System for achieving a safe vascular control, compared with previous techniques. METHODS: LigaSure is an energy-based device which works by applying a precise amount of bipolar energy and pressure to the tissue, thus achieving a permanent seal...
December 2003: Pediatric Surgery International
No abstract text is available yet for this article.
September 15, 1957: Experientia
M Caltabiano, P Verzì, R Leonardi
40 patients with talassemia major treated with blood transfusions were studied by the Authors. The aim of this study was to evaluate tmj signs and symptoms, according to Helkimo questionnaire. From the data collected in this investigation it comes out that clinical signs are more frequent in older subjects, in fact 27% of young patients aged from 9 to 13 years showed at least one clinical sign of dysfunction; on the other hand in the younger patients (aged from 6 to 9 years) dysfunctions were found only in 16% of subjects...
October 1990: Rivista Italiana di Odontoiatria Infantile
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