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sublobar lobectomy

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https://www.readbyqxmd.com/read/28523166/a-novel-hybrid-technique-for-localization-of-subcentimeter-lung-nodules
#1
Xuguang Pang, Liang Xue, Jiemin Chen, Jianyong Ding
BACKGROUND: It is technically challenging to locate non-visible, non-palpable subcentimeter ground-glass nodules (GGNs) of lung during video-assisted thoracic surgery (VATS). Computed tomography (CT)-guided marking of small pulmonary nodules using microcoils has been reported to be a practical method of preoperative localization, whereas dislodgement of microcoils remains to be a bothersome complication. The objective of this study was to assess the viability and effectiveness of a newly developed hybrid technique, which combines induced controllable pneumothorax and CT-guided microcoil marking procedure to reduce the risk of microcoil dislodgement...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28483268/outcomes-after-lobar-versus-sublobar-resection-for-clinical-stage-i-non-small-cell-lung-cancer-in-patients-with-interstitial-lung-disease
#2
Yasuhiro Tsutani, Takeshi Mimura, Yuichiro Kai, Masaoki Ito, Keizo Misumi, Yoshihiro Miyata, Morihito Okada
OBJECTIVE: Since the prognosis after standard lobectomy for non-small cell lung cancer (NSCLC) in patients with interstitial lung disease (ILD) is poor, we investigated the possibility of sublobar resection for the improvement of the surgical results in such patients. METHODS: Of 796 consecutive patients with clinical stage I NSCLC who underwent pulmonary resection, 107 were diagnosed with ILD using high-resolution computed tomography (HRCT). Overall survivals (OS) were compared between patients with non-ILD and those with ILD or between patients with ILD who underwent lobectomy and those who underwent sublobar resection...
April 4, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28476421/treatment-of-stage-i-non-small-cell-lung-cancer-what-s-trending
#3
Timothy L McMurry, Puja M Shah, Pamela Samson, Clifford G Robinson, Benjamin D Kozower
OBJECTIVES: Stage I non-small cell lung cancer traditionally is treated with lobectomy. Sublobar resection and stereotactic body radiation therapy provide alternative treatments for higher-risk groups. The purpose of this study was to determine the national treatment trends for stage I lung cancer. METHODS: The National Cancer Database was queried for patients with clinical stage I non-small cell lung cancer between 1998 and 2012. Patients were compared across treatment groups, and trends in treatment and disease were evaluated over the 15-year time period...
April 5, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28461054/a-national-analysis-of-wedge-resection-versus-stereotactic-body-radiation-therapy-for-stage-ia-non-small-cell-lung-cancer
#4
Babatunde A Yerokun, Chi-Fu Jeffrey Yang, Brian C Gulack, Xuechan Li, Michael S Mulvihill, Lin Gu, Xiaofei Wang, David H Harpole, Thomas A D'Amico, Mark F Berry, Matthew G Hartwig
OBJECTIVE: Lobectomy is considered optimal therapy for early-stage non-small cell lung cancer, but sublobar wedge resection and stereotactic body radiation therapy are alternative treatments. This study compared outcomes between wedge resection and stereotactic body radiotherapy. METHODS: Overall survival of patients with cT1N0 and tumors ≤2 cm who underwent stereotactic body radiotherapy or wedge resection in the National Cancer Data Base from 2008 to 2011 was assessed via a Kaplan-Meier and propensity score-matched analysis...
April 4, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28449533/can-mathematics-replace-anatomy-to-establish-recommendations-in-lung-cancer-surgery
#5
EDITORIAL
Marc Riquet, Ciprian Pricopi, Antoine Legras, Alex Arame, Alain Badia, Françoise Le Pimpec Barthes
The greater the number of lymph node (LN) sampled (NLNsS) during lung cancer surgery, the lower the risk of underestimating the pN-status and the better the outcome of the pN0-patients due to stage-migration. Thus, regarding LN sampling "to be or not to be", number is the question. Recent studies advocate removing 10 LNs. The most suitable NLNsS is unfortunately impossible to establish by mathematics. A too high NLNsS variability exists, based on anatomy, surgery and pathology. The methodology may vary according to Inter-institutional differences in the surgical approach regarding LN inspection and number sampling...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28447170/surgery-or-stereotactic-body-radiotherapy-for-elderly-stage-i-lung-cancer-a-propensity-score-matching-analysis
#6
Takuro Miyazaki, Takuya Yamazaki, Daisuke Nakamura, Shuntaro Sato, Naoya Yamasaki, Tomoshi Tsuchiya, Keitaro Matsumoto, Ryotaro Kamohara, Go Hatachi, Takeshi Nagayasu
PURPOSE: The aim of this study was to compare the outcomes of surgery and stereotactic body radiotherapy (SBRT) for elderly clinical stage I non-small cell lung cancer (NSCLC) patients. METHODS: Patients ≥80 years of age with clinical stage I NSCLC between August 2008 and December 2014 were treated either surgery or SBRT. Propensity score matching was performed to reduce bias in various clinicopathological factors. RESULTS: Surgery was performed in 57 cases and SBRT in 41 cases...
April 26, 2017: Surgery Today
https://www.readbyqxmd.com/read/28446986/sublobar-resection-for-stage-ia-non-small-cell-lung-cancer
#7
REVIEW
Kathleen S Berfield, Douglas E Wood
Advancements in the diagnosis, staging and management of lung cancer have all led to improvements in outcomes associated with sublobar resection. Lobectomy, for early stage lung cancers has been the treatment of choice for many years. However, there is mounting evidence that sublobar resection when applied to the appropriate patient population can provide not only excellent oncologic results but also equivalent survival to lobectomy. Therefore, it is time that we reevaluate the management of peripheral stage IA lung cancers...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28446985/whack-a-mole-strategy-for-multifocal-ground-glass-opacities-of-the-lung
#8
REVIEW
Kenji Suzuki
Ground glass opacity (GGO) is a good prognostic indicator for lung cancer and is useful for physicians to predict prognosis. Due to recent advances in computed tomography (CT), the chance to encounter GGO is rapidly increasing in clinical practice. Based on the studies on radiological pathological correlation, GGO represents pathological lepidic growth and consolidation on CT represents pathologically invasive components. Thus, consolidation tumor ratio 0.5 or less means pathological less invasiveness for lung cancer...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28419333/surgical-resection-for-clinical-stage-i-radiological-pure-solid-lung-cancer-that-met-the-current-high-risk-criteria
#9
Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Shiaki Oh, Kenji Suzuki
Objective: We assessed whether surgical resection is acceptable for radiological invasive non-small cell lung cancer (NSCLC) that met the current high-risk criteria. Methods: We reviewed 500 clinical-Stage I NSCLCs with a radiological pure-solid appearance. High-risk criterion was defined as follows: (1) preoperative FEV1% ≤ 50% or DLco% ≤ 50%, (2) age > 75y with 50% < FEV1% < 60% or 50% < DLco% < 60%, and (3) three or more severe general comorbidities...
April 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28407246/trimodality-therapy-for-pancoast-tumors-t4-is-not-a-contraindication-to-radical-surgery
#10
Ryuichi Waseda, Thomas Klikovits, Mir Alireza Hoda, Konrad Hoetzenecker, Pietro Bertoglio, Karin Dieckmann, Sabine Zöchbauer-Müller, Robert Pirker, Helmut Prosch, Balazs Döme, Walter Klepetko
OBJECTIVE: This study aims to evaluate the impact of T stage and extended surgery on the outcome of patients with Pancoast tumors after induction chemoradiation therapy. METHODS: Forty-six consecutive patients who underwent chemoradiation therapy (platin-based, 45-66 Gy) followed by surgery between 1998 and 2013 were retrospectively reviewed and analyzed. RESULTS: In 28 (61%) patients with T4 tumors, extended procedures (more than rib resection) were performed...
April 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28402455/stage-i-non-small-cell-lung-cancer-long-term-results-of-lobectomy-versus-sublobar-resection-from-the-polish-national-lung-cancer-registry%C3%A2
#11
Robert Dziedzic, Wojciech Zurek, Tomasz Marjanski, Piotr Rudzinski, Tadeusz M Orlowski, Wioletta Sawicka, Michal Marczyk, Joanna Polanska, Witold Rzyman
OBJECTIVES: Anatomical lobar resection and mediastinal lymphadenectomy remain the standard for the treatment of early stage non-small-cell lung cancer (NSCLC) and are preferred over procedures such as segmentectomy or wedge resection. However, there is an ongoing debate concerning the influence of the extent of the resection on overall survival. The aim of this article was to assess the overall survival for different types of resection for Stage I NSCLC. METHODS: We performed a retrospective analysis of the results of the surgical treatment of Stage I NSCLC...
April 11, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28366461/sublobar-resection-for-pulmonary-aspergilloma-a-safe-alternative-to%C3%A2-lobectomy
#12
Ping Yuan, Jin-Lin Cao, Sha Huang, Chong Zhang, Fei-Chao Bao, Ye-Ji Hu, Wang Lv, Jian Hu
BACKGROUND: This study was performed to evaluate the effectiveness of sublobar resection for the treatment of pulmonary aspergilloma compared with lobectomy. METHODS: Patients with pulmonary aspergilloma who underwent lobectomy or sublobar resection in our department between March 2007 and December 2015 were retrospectively reviewed. Data were collected for patient demographic characteristics, medical history, preoperative investigations, perioperative findings, postoperative conditions, and recurrence status...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28331339/chronological-changes-in-lung-cancer-surgery-in-a-single-japanese-institution
#13
Haruhiko Nakamura, Hiroki Sakai, Hiroyuki Kimura, Tomoyuki Miyazawa, Hideki Marushima, Hisashi Saji
BACKGROUND: The aim of this study was to evaluate the chronological changes in epidemiological factors and surgical outcomes in patients with lung cancer who underwent surgery in a single Japanese institution. PATIENTS AND METHODS: A clinicopathological database of patients with lung cancer who underwent surgery with curative intent from January 1974 to December 2014 was reviewed. The chronological changes in various factors, including patient's age, sex, histological type, tumor size, pathological stage (p-stage), surgical method, operative time, intraoperative blood loss, 30-day mortality, and postoperative overall survival (OS), were evaluated...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28301349/influence-of-extent-of-lymph-node-evaluation-on-survival-for-pathologically-lymph-node-negative-non-small-cell-lung-cancer
#14
Daniel J Becker, Benjamin P Levy, Heather T Gold, Scott E Sherman, Danil V Makarov, David Schreiber, Juan P Wisnivesky, Harvey I Pass
OBJECTIVES: Despite previous retrospective reports that the number of lymph nodes resected at curative intent surgery for lung cancer correlates with overall survival (OS), no consensus exists regarding the minimal nor optimal number of lymph nodes to resect at curative lung cancer surgery. METHODS: We studied subjects in the Surveillance Epidemiology and End Results Database (SEER) diagnosed with non-small cell lung cancer between 2000 and 2011 who underwent either lobectomy or pneumonectomy and had pathologic negative nodal evaluation...
March 15, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28274562/biopsy-first-lessons-learned-from-cancer-and-leukemia-group-b-calgb-140503
#15
Leslie J Kohman, Lin Gu, Nasser Altorki, Ernest Scalzetti, Linda J Veit, Jason M Wallen, Xiaofei Wang
OBJECTIVE: Cancer and Leukemia Group B 140503 is an ongoing, multicenter randomized trial assessing whether sublobar resection is equivalent to lobectomy for the treatment of stage I A non-small cell lung cancer (NSCLC) ≤2 cm in diameter. The objective of this report is to determine the reasons precluding intraoperative randomization. METHODS: From June 15, 2007, to March 22, 2013, 637 patients were preregistered to the trial. Three hundred eighty-nine were randomized successfully (61%), and 248 patients were not randomized (39%)...
February 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28267977/indications-for-adjuvant-mediastinal-radiotherapy-in-surgically-resected-small-cell-lung-cancer
#16
Elliot Wakeam, Meredith Giuliani, Natasha B Leighl, Samuel R G Finlayson, Thomas K Varghese, Gail E Darling
BACKGROUND: Adjuvant mediastinal radiotherapy (AMR) is used after surgical resection for patients with small cell lung cancer (SCLC), but data guiding its use are scant. We sought to examine whether AMR was associated with an improvement in survival for resected SCLC patients and to define subpopulations who should be selected for AMR. METHODS: Patients undergoing lobectomy, pneumonectomy, and sublobar resection for SCLC were identified in the National Cancer Database (2004 to 2013)...
March 3, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28251378/role-of-segmentectomy-in-treatment-of-early-stage-non-small-cell-lung-cancer
#17
Mark Hennon, Rodney J Landreneau
PURPOSE AND DESIGN: Standard treatment for early-stage non-small cell lung cancer has traditionally involved lobectomy. Historical data that demonstrates suboptimal results for sublobar resection compared to lobectomy have been challenged in recent years with retrospective data for patients with T1a disease. For patients who are not candidates for lobectomy, options for sublobar resection include wedge resection or anatomic segmentectomy. Segmentectomy has long been held to be a better cancer operation than wedge resection, and its role in treating early-stage lung cancer remains controversial in patients who are candidates for lobectomy...
March 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28204910/outcomes-of-curative-intent-surgery-and-adjuvant-treatment-for-pulmonary-large-cell-neuroendocrine-carcinoma
#18
Kun Woo Kim, Hong Kwan Kim, Jhingook Kim, Young Mog Shim, Myung-Ju Ahn, Yoon-La Choi
BACKGROUND: Pulmonary large cell neuroendocrine carcinoma (LCNEC) is pathologically classified as non-small-cell lung cancer (NSCLC), but its clinical behavior is more aggressive than other types of NSCLC. Accordingly, the optimal treatment strategy for LCNEC, including the indication of adjuvant treatment, remains controversial. METHODS: A retrospective review of 139 patients who underwent curative-intent surgery for LCNEC was performed to investigate clinicopathologic features and survival outcomes and to evaluate whether adjuvant treatment affected survival outcomes...
February 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28186277/radiotherapy-lobectomy-or-sublobar-resection-a-meta-analysis-of-the-choices-for-treating-stage-i-non-small-cell-lung-cancer
#19
Han-Yu Deng, Yun-Cang Wang, Peng-Zhi Ni, Gang Li, Xiao-Yan Yang, Yi-Dan Lin, Lun-Xu Liu
No abstract text is available yet for this article.
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28103973/-propensity-score-matching-analysis-of-vats-lobectomy-and-sublobar-resection-for-stage-i-lung-adenocarcinoma
#20
Yang Liu, Shengyi Zhong, Qihua He, Jianrong Zhang, Xuewei Chen, Minzhang Guo, Jianxing He
BACKGROUND: National Comprehensive Cancer Network (NCCN) guidelines recommend video-assisted thoracoscopic surgery (VATS) anatomical lobectomy as the first choice for the treatment of resectable lung cancer. However, sublobar resection offers significantly better functional preservation compared with lobectomy for stage I lung cancer. At present, the inferiority of sublobar resection to lobectomy is still uncertain. Herein, we compared the prognoses of these two types of surgical treatment for stage I lung adenocarcinoma...
January 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
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