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sublobar lobectomy

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https://www.readbyqxmd.com/read/28204910/outcomes-of-curative-intent-surgery-and-adjuvant-treatment-for-pulmonary-large-cell-neuroendocrine-carcinoma
#1
Kun Woo Kim, Hong Kwan Kim, Jhingook Kim, Young Mog Shim, Myung-Ju Ahn, Yoon-La Choi
BACKGROUND: Pulmonary large cell neuroendocrine carcinoma (LCNEC) is pathologically classified as non-small-cell lung cancer (NSCLC), but its clinical behavior is more aggressive than other types of NSCLC. Accordingly, the optimal treatment strategy for LCNEC, including the indication of adjuvant treatment, remains controversial. METHODS: A retrospective review of 139 patients who underwent curative-intent surgery for LCNEC was performed to investigate clinicopathologic features and survival outcomes and to evaluate whether adjuvant treatment affected survival outcomes...
February 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28186277/radiotherapy-lobectomy-or-sublobar-resection-a-meta-analysis-of-the-choices-for-treating-stage-i-non-small-cell-lung-cancer
#2
Han-Yu Deng, Yun-Cang Wang, Peng-Zhi Ni, Gang Li, Xiao-Yan Yang, Yi-Dan Lin, Lun-Xu Liu
No abstract text is available yet for this article.
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28103973/-propensity-score-matching-analysis-of-vats-lobectomy-and-sublobar-resection-for-stage-i-lung-adenocarcinoma
#3
Yang Liu, Shengyi Zhong, Qihua He, Jianrong Zhang, Xuewei Chen, Minzhang Guo, Jianxing He
BACKGROUND: National Comprehensive Cancer Network (NCCN) guidelines recommend video-assisted thoracoscopic surgery (VATS) anatomical lobectomy as the first choice for the treatment of resectable lung cancer. However, sublobar resection offers significantly better functional preservation compared with lobectomy for stage I lung cancer. At present, the inferiority of sublobar resection to lobectomy is still uncertain. Herein, we compared the prognoses of these two types of surgical treatment for stage I lung adenocarcinoma...
January 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28089646/a-risk-score-to-predict-the-incidence-of-prolonged-air-leak-after-video-assisted-thoracoscopic-lobectomy-an-analysis-from-the-european-society-of-thoracic-surgeons-database
#4
Cecilia Pompili, Pierre Emmanuel Falcoz, Michele Salati, Zalan Szanto, Alessandro Brunelli
OBJECTIVE: The study objective was to develop an aggregate risk score for predicting the occurrence of prolonged air leak after video-assisted thoracoscopic lobectomy from patients registered in the European Society of Thoracic Surgeons database. METHODS: A total of 5069 patients who underwent video-assisted thoracoscopic lobectomy (July 2007 to August 2015) were analyzed. Exclusion criteria included sublobar resections or pneumonectomies, lung resection associated with chest wall or diaphragm resections, sleeve resections, and need for postoperative assisted mechanical ventilation...
December 22, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28066606/lobectomy-and-limited-resection-in-small-sized-peripheral-non-small-cell-lung-cancer
#5
Terumoto Koike, Teruaki Koike, Seijiro Sato, Takehisa Hashimoto, Tadashi Aoki, Katsuo Yoshiya, Yasushi Yamato, Takehiro Watanabe, Kohei Akazawa, Shin-Ichi Toyabe, Masanori Tsuchida
BACKGROUND: Although lobectomy is the standard surgical procedure for non-small cell lung cancer (NSCLC), recent studies show favorable outcomes after limited resection in patients with small-sized peripheral tumors. We conducted a randomized controlled trial of such patients to estimate postoperative outcomes and pulmonary function following these surgical techniques. METHODS: Between 2005 and 2008, eligible patients with tumors of 2 cm or less were randomly assigned 1:1 to undergo lobectomy or limited resection; 32 and 33 NSCLC patients in each group, respectively, were analyzed...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28049169/management-of-stage-i-and-ii-nonsmall-cell-lung-cancer
#6
Fiona McDonald, Michèle De Waele, Lizza E L Hendriks, Corinne Faivre-Finn, Anne-Marie C Dingemans, Paul E Van Schil
The incidence of stage I and II nonsmall cell lung cancer is likely to increase with the ageing population and introduction of screening for high-risk individuals. Optimal management requires multidisciplinary collaboration. Local treatments include surgery and radiotherapy and these are currently combined with (neo)adjuvant chemotherapy in specific cases to improve long-term outcome. Targeted therapies and immunotherapy may also become important therapeutic modalities in this patient group. For resectable disease in patients with low cardiopulmonary risk, complete surgical resection with lobectomy remains the gold standard...
January 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28005439/early-lung-cancer-detection-by-low-dose-ct-screening-therapeutic-implications
#7
Marjolein A Heuvelmans, Harry J M Groen, Matthijs Oudkerk
Lung cancer screening by low-dose chest computed tomography is currently implemented in the U.S. After implementation of screening, a stage shift may be observed from around 15% stage I non-small cell lung cancers (NSCLCs) in routine clinical practice to up to 70% in screening patients. This indicates a move in treatment options from advanced to early lung cancers, especially in those with small suspected intrapulmonary nodules. Areas covered: We have reviewed the current status of lung cancer screening from the different randomized controlled lung cancer screening studies and the clinical evidence so far for both surgical and non-surgical treatment options for (screen-detected) stage I NSCLC...
December 30, 2016: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27964917/clinical-significance-of-positron-emission-tomography-in-subcentimeter-non-small-cell-lung-cancer
#8
Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Shiaki Oh, Kenji Suzuki
BACKGROUND: This study evaluated the clinical significance of maximum standardized uptake value (SUVmax) on positron emission tomography (PET) in patients with subcentimeter non-small cell lung cancer (NSCLC). METHODS: Between 2008 and 2014, 189 patients were investigated preoperatively by PET for c-N0 subcentimeter NSCLC, and SUVmax was reviewed. Pathologic invasiveness (PI) was defined as having at least one of the following factors: lymphatic invasion, vascular invasion, pleural invasion, or nodal metastasis...
December 10, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27823756/comparison-of-pulmonary-function-tests-and-perioperative-outcomes-after-robotic-assisted-pulmonary-lobectomy-vs-segmentectomy
#9
Maria F Echavarria, Anna M Cheng, Frank O Velez-Cubian, Emily P Ng, Carla C Moodie, Joseph R Garrett, Jacques P Fontaine, Lary A Robinson, Eric M Toloza
BACKGROUND: Lobectomy is standard treatment for early-stage lung cancer, but sublobar resection remains debated. We compared outcomes after robotic-assisted video-assisted thoracoscopic (R-VATS) segmentectomy vs lobectomy. METHODS: We retrospectively analyzed data from 251 consecutive patients who underwent R-VATS lobectomy (n = 208) or segmentectomy (n = 43) by a single surgeon over 36 months. Pulmonary function tests and perioperative outcomes were compared using Chi-squared test, unpaired Student t test, or Kruskal-Wallis test, with significance at P ≤ ...
December 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27803991/outcomes-of-surgery-for-lung-cancer-in-patients-with-atrial-fibrillation-as-a-preoperative-comorbidity-a-decade-of-experience-at-a-single-institution-in-japan
#10
Ryu Kanzaki, Toru Kimura, Tomohiro Kawamura, Soichiro Funaki, Yasushi Shintani, Masato Minami, Meinoshin Okumura
PURPOSE: To investigate the surgical outcomes of surgery for non-small cell lung cancer (NSCLC) in patients with atrial fibrillation (AF) as a preoperative comorbidity. METHODS: Among 805 patients who underwent surgery for NSCLC, 27 (3.4%) had a history of AF. We analyzed the perioperative and long-term outcomes of these 27 patients. RESULTS: Fourteen patients (52%) had chronic AF and 13 (48%) had paroxysmal AF; being high rates of a comorbid illness...
November 1, 2016: Surgery Today
https://www.readbyqxmd.com/read/27746190/role-of-postoperative-radiotherapy-in-pathologic-stage-iiia-n2-non-small-cell-lung-cancer-in-a-prospective-nationwide-oncology-outcomes-database
#11
Alex Herskovic, Elizabeth Mauer, Paul Christos, Himanshu Nagar
INTRODUCTION: The role of postoperative radiotherapy (PORT) in the treatment of pathologic stage IIIA (N2) NSCLC remains controversial. We investigated practice patterns and outcomes for these patients in a prospectively maintained nationwide oncology outcomes database. METHODS: Patients with known histologic features of pathologic stage IIIA (N2) NSCLC who underwent an operation with negative margins and received adjuvant multiagent chemotherapy from 2004 to 2013 were identified from the National Cancer Data Base and stratified by the use of PORT...
October 14, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27732992/surgical-treatment-of-early-l-stage-lung-cancer-what-has-changed-and-what-will-change-in-the-future
#12
Huan H Sun, Joanna Sesti, Jessica S Donington
Recent advances in the surgical treatment of early stage non-small cell lung cancer (NSCLC) have focused heavily on making procedures less invasive, less radical, and better tolerated. Advances in accuracy and increased utilization of cross-sectional imaging allows for diagnosis of smaller and more indolent tumors and preinvasive lesions. Similar to advanced disease, early-stage treatment is now being tailored to individual patients and their tumors. Sublobar resections are gaining acceptance as an oncologically equivalent approach to lobectomy in well-selected stage I patients...
October 2016: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27687830/normal-postoperative-appearances-of-lung-cancer
#13
S Bommart, J P Berthet, G Durand, B Ghaye, J L Pujol, C Marty-Ané, H Kovacsik
The major lung resections are the pneumonectomies and lobectomies. The sublobar resections are segmentectomies and wedge resections. These are performed either through open surgery through a thoracotomy or by video-assisted mini-invasive surgery for lobectomies and sublobar resections. Understanding the procedures involved allows the normal postoperative appearances to be interpreted and these normal anatomical changes to be distinguished from potential postoperative complications. Surgery results in a more or less extensive physiological adaptation of the chest cavity depending on the lung volume, which has been resected...
October 2016: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/27674728/comparative-effectiveness-of-lobectomy-sublobar-resection-and-stereotactic-body-radiation-therapy-for-clinical-stage-i-non-small-cell-lung-cancer-a-propensity-matched-analysis
#14
T Shaikh, T M Churilla, C T Murphy, M A Hallman, W J Scott, J E Meyer
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27621855/risk-factors-for-recurrence-after-sublobar-resection-in-patients-with-small-2-cm-or-less-non-small-cell-lung-cancer-presenting-as-a-solid-predominant-tumor-on-chest-computed-tomography
#15
Youngkyu Moon, Sook Whan Sung, Seok Whan Moon, Jae Kil Park
BACKGROUND: Sublobar resection is considered controversial for non-small cell lung cancer (NSCLC) presenting as a solid-predominant nodule. The aim of this study was to identify risk factors related to recurrence in small-sized NSCLC presenting as a solid-predominant nodule. METHODS: We conducted a retrospective chart review of 118 patients who were treated for clinical N0 NSCLC sized ≤2 cm and who underwent sublobar resection with clear resection margins. We assigned them to two groups according to radiologic features: ground glass opacity (GGO)-predominant tumor and solid-predominant tumor...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27592602/a-risk-score-to-assist-selecting-lobectomy-versus-sublobar-resection-for-early-stage-non-small-cell-lung-cancer
#16
Brian C Gulack, Chi-Fu Jeffrey Yang, Paul J Speicher, Babatunde A Yerokun, Betty C Tong, Mark W Onaitis, Thomas A D'Amico, David H Harpole, Matthew G Hartwig, Mark F Berry
BACKGROUND: The long-term survival benefit of lobectomy over sublobar resection for early-stage non-small cell lung cancer must be weighed against a potentially increased risk of perioperative mortality. The objective of the current study was to create a risk score to identify patients with favorable short-term outcomes following lobectomy. METHODS: The 2005-2012 American College of Surgeons National Surgical Quality Improvement Program database was queried for patients undergoing a lobectomy or sublobar resection (either segmentectomy or wedge resection) for lung cancer...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27590672/radiotherapy-lobectomy-or-sublobar-resection-a-meta-analysis-of-the-choices-for-treating-stage-i-non-small-cell-lung-cancer
#17
Han-Yu Deng, Yun-Cang Wang, Peng-Zhi Ni, Gang Li, Xiao-Yan Yang, Yi-Dan Lin, Lun-Xu Liu
SummaryWhether stereotactic ablative radiotherapy (SABR) is comparable to surgery in treating stage I non-small-cell lung cancer (NSCLC) is unknown. Therefore, we conducted this meta-analysis to compare the efficacy of SABR with that of surgery in treating stage I NSCLC. A systematic literature search in PubMed, Embase, Cochrane Library databases and Google Scholar as well as the American Society of Clinical Oncology was conducted to identify relevant studies dated through 31 December 2015. Data including 3-year survival rate, overall survival (OS) and 3-year loco-regional control (LRC) rates were extracted and analysed...
September 1, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27568150/novel-methods-of-intraoperative-localization-and-margin-assessment-of-pulmonary-nodules
#18
Jane Keating, Sunil Singhal
Lung cancer screening has lead to frequent diagnosis of solitary pulmonary nodules, many of which require surgical biopsy for diagnosis and intervention. Subcentimeter and central nodules are particularly difficult to visualize or palpate during surgery, thus nodule localization can be a difficult problem for the thoracic surgeon. Although minimally invasive techniques including transthoracic computed tomography and bronchoscopic-guided biopsy may establish a diagnosis, these methods do not help locate nodules during surgery and can lead to inadequate tissue sampling...
2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27537191/adherence-to-a-clinical-pathway-for-video-assisted-thoracic-surgery-predictors-and-clinical-importance
#19
Alan D L Sihoe, Peter S Y Yu, Timothy H Kam, S Y Lee, Xuyuan Liu
OBJECTIVE: A bespoke clinical pathway is increasingly often used to expedite patient's recovery after video-assisted thoracoscopic surgery (VATS). The importance and predictors of adherence to a clinical pathway have not been previously investigated. METHODS: A defined clinical pathway was used for the perioperative management of 136 consecutive patients receiving major pulmonary resection surgery. The clinical pathway encompassed multiple aspects of clinical care, including chest drainage, analgesia, mobilization, physiotherapy, investigations, etc...
May 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27531307/rationale-for-a-minimum-number-of-lymph-nodes-removed-with-non-small-cell-lung-cancer-resection-correlating-the-number-of-nodes-removed-with-survival-in-98-970-patients
#20
Andres X Samayoa, Todd A Pezzi, Christopher M Pezzi, E Greer Gay, Megumi Asai, Nandini Kulkarni, Ned Carp, Stephen G Chun, Joe B Putnam
BACKGROUND: The benefit of thoracic lymphadenectomy in the treatment of resectable non-small cell lung cancer (NSCLC) continues to be debated. We hypothesized that the number of lymph nodes (LNs) removed for patients with pathologic node-negative NSCLC would correlate with survival. METHODS: The National Cancer Data Base (NCDB) was queried for resected, node-negative, NSCLC patients treated between 2004 and 2014. Patients were grouped according to the number of LNs removed (1-4, 5-8, 9-12, 13-16, and ≥17)...
December 2016: Annals of Surgical Oncology
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