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sublobar lobectomy

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https://www.readbyqxmd.com/read/29397101/outcomes-for-thoracoscopy-versus-thoracotomy-not-just-technique-dependent-a%C3%A2-study-of-9-787-patients
#1
Andrea Wolf, Bian Liu, Emanuele Leoncini, Daniel Nicastri, Dong-Seok Lee, Emanuela Taioli, Raja Flores
BACKGROUND: Studies reporting the benefits of video-assisted thoracoscopic surgery (VATS) lung cancer resection over thoracotomy have been subject to selection bias. We evaluated patient and hospital characteristics associated with type of surgery and the independent effect of VATS on outcomes. METHODS: The Statewide Planning and Research Cooperative System of New York State database was queried to identify all lung cancer patients undergoing lobectomy or sublobar resection between 2007 and 2012...
January 31, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29357967/-prognostic-analysis-of-lobectomy-versus-sublobar-resection-in-patients-aged-%C3%A2-60-years-with-stage-ia-small-cell-lung-cancer
#2
Haikang Zeng, Yang Liu, Xiaojun Xia, Jin Li, Jianxing He
BACKGROUND: Currently, the prognosis of lobectomy and sub-lobectomy for the treatment of stage Ia small cell lung cancer (SCLC) is rarely reported. We retrospectively studied T1N0M0 (≤3 cm) SCLC patients aged ≥60 years, aiming to comparatively analyze the prognosis of lobectomy and sub-lobectomy in treating patients with Ia SCLC. METHODS: Patients with stage Ia SCLC diagnosed by pathologic between 1992 and 2010 were selected from the "Surveillance, Epidemiology and End Results database"(SEER)...
January 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/29346041/post-treatment-mortality-after-surgery-and-stereotactic-body-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#3
William A Stokes, Michael R Bronsert, Robert A Meguid, Matthew G Blum, Bernard L Jones, Matthew Koshy, David J Sher, Alexander V Louie, David A Palma, Suresh Senan, Laurie E Gaspar, Brian D Kavanagh, Chad G Rusthoven
Purpose In early-stage non-small cell lung cancer (NSCLC), post-treatment mortality may influence the comparative effectiveness of surgery and stereotactic body radiotherapy (SBRT), with implications for shared decision making among high-risk surgical candidates. We analyzed early mortality after these interventions using the National Cancer Database. Patients and Methods We abstracted patients with cT1-T2a, N0, M0 NSCLC diagnosed between 2004 and 2013 undergoing either surgery or SBRT. Thirty-day and 90-day post-treatment mortality rates were calculated and compared using Cox regression and propensity score-matched analyses...
January 18, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29246549/factors-associated-with-distant-recurrence-following-r0-lobectomy-for-pn0-lung-adenocarcinoma
#4
Whitney S Brandt, Ilies Bouabdallah, Kay See Tan, Bernard J Park, Prasad S Adusumilli, Daniela Molena, Manjit S Bains, James Huang, James M Isbell, Matthew J Bott, David R Jones
OBJECTIVE: We investigated factors associated with distant recurrence, disease-free survival (DFS), and overall survival (OS) following R0 lobectomy for pathologic node-negative (pN0) lung adenocarcinoma. METHODS: We performed a retrospective analysis of a prospectively maintained database of patients with pT1-3N0M0 non-small cell lung cancer. Exclusion criteria included metachronous lung cancer, sublobar/incomplete resection, nonadenocarcinoma histology, and induction/adjuvant therapy...
November 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29236995/a-prospective-5-year-follow-up-study-after-limited-resection-for-lung-cancer-with-ground-glass-opacity
#5
Motoyasu Sagawa, Hiroyuki Oizumi, Hiroyuki Suzuki, Hidetaka Uramoto, Katsuo Usuda, Akira Sakurada, Masayuki Chida, Satoshi Shiono, Jiro Abe, Tohru Hasumi, Masami Sato, Nobuyuki Sato, Jotaro Shibuya, Hiroyuki Deguchi, Yoshinori Okada
OBJECTIVES: The incidence of small-sized pulmonary adenocarcinomas with ground-glass opacity (GGO) has recently increased, with excellent postoperative prognosis. The limited resection of such cancers has been deemed to be acceptable based on retrospective studies. We conducted a prospective multi-institutional study evaluating the validity of limited resection for small-sized pulmonary adenocarcinoma with GGO. METHODS: The inclusion criteria were 25-80 years of age, no prior treatment, a maximum tumour diameter of 8-20 mm, a GGO ratio of ≥ 80%, clinical T1N0M0, lower 18F-fluorodeoxyglucose accumulation than the mediastinum, resectable by sublobar resection, pulmonary lobectomy tolerable and an intraoperative pathological diagnosis of bronchiloalveolar carcinoma...
December 9, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29234607/lobectomy-versus-sublobar-resection-in-non-lepidic-small-sized-non-small-cell-lung-cancer
#6
Min Namkoong, Youngkyu Moon, Jae Kil Park
Background: Recently, many surgeons have chosen sublobar resection for the curative treatment of lung tumors with ground-glass opacity, which is a hallmark of lepidic lung cancer. The purpose of this study was to evaluate the oncological results of sublobar resection for non-lepidic lung cancer in comparison with lobectomy. Methods: We conducted a retrospective chart review of 328 patients with clinical N0 non-small cell lung cancer sized ≤2 cm who underwent curative surgical resection from January 2009 to December 2014...
December 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29221263/a-prospective-randomized-trial-comparing-homologous-and-autologous-fibrin-sealants-for-the-control-of-alveolar-air-leak
#7
Burcu Kılıç, Ezel Erşen, Ahmet Demirkaya, H Volkan Kara, Nurlan Alizade, Mehlika İşcan, Kamil Kaynak, Akif Turna
Background: Postoperative air leak is a common complication seen after pulmonary resection. It is a significant reason of morbidity and also leads to greater hospital cost owing to prolonged length of stay. The purpose of this study is to compare homologous sealant with autologous one to prevent air leak following pulmonary resection. Methods: A total of 57 patients aged between 20 and 79 (mean age: 54.36) who underwent pulmonary resection other than pneumonectomy (lobar or sublobar resections) were analyzed...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29198624/stereotactic-body-radiation-therapy-versus-surgery-for-early-lung-cancer-among-us%C3%A2-veterans
#8
Alex K Bryant, Robert C Mundt, Ajay P Sandhu, James J Urbanic, Andrew B Sharabi, Samir Gupta, Megan E Daly, James D Murphy
BACKGROUND: Stereotactic body radiation therapy (SBRT) has been proposed as a potential alternative to surgery for early lung cancer, although we lack well-powered prospective randomized data comparing these treatments, and existing studies suffer from incomplete information on confounders that can bias results. Here, we evaluated the comparative effectiveness of surgery and SBRT in lung cancer treatment using a large extensively detailed database from the Veteran's Affairs system. METHODS: We identified veterans with biopsy-proven clinical stage I non-small cell lung cancer diagnosed between 2006 and 2015 from within the Veteran's Affairs Informatics and Computing Infrastructure...
November 21, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29192744/thirty-day-mortality-and-five-year-survival-in-thoracic-surgery-real-world-assessment-of-outcomes-from-a-single-institution-audit
#9
Anna Cantarutti, Carlotta Galeone, Giovanni Leuzzi, Elena Bertocchi, Giovanna Pomponi, Martin Langer, Vincenzo Mazzaferro, Gustavo Galmozzi, Giovanni Apolone, Giovanni Corrao, Ugo Pastorino
BACKGROUND: Accurate measurement of outcomes is essential to monitor the effectiveness of public health policies. In Italy, the Ministry of Health has chosen 30-day mortality after major surgical or medical procedures as the main outcome measure, pooling all pulmonary resections for malignancy in a single category. The present audit evaluated all pulmonary resections performed over a 13-year period in a single institution to assess the immediate (30-day mortality) and long-term (5-year survival) outcomes according to type and stage of disease and extent of surgery...
November 21, 2017: Tumori
https://www.readbyqxmd.com/read/29174780/hospitalization-costs-after-surgery-in-high-risk-patients-with-early-stage-lung-cancer
#10
Manu S Sancheti, Ray K Chihara, Sebastian D Perez, Onkar V Khullar, Felix G Fernandez, Allan Pickens, Seth D Force
BACKGROUND: We previously reported that early stage lung cancer patients who are considered high risk for surgery can undergo resection with favorable perioperative results and long-term mortality. To further elucidate the role of surgical resection in this patient cohort, this study evaluated the length of stay and total hospitalization cost among patients classified as standard or high risk with early stage lung cancer who underwent pulmonary resection. METHODS: A total of 490 patients from our institutional Society of Thoracic Surgeons data from 2009 to 2013 underwent resection for clinical stage I lung cancer...
November 23, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29132704/extent-of-resection-and-lymph-node-assessment-for-clinical-stage-t1an0m0-typical-carcinoid-tumors
#11
Lisa M Brown, David T Cooke, James R Jett, Elizabeth A David
BACKGROUND: The optimal extent of lung resection and lymph node (LN) assessment for surgical treatment of clinical stage T1aN0M0 typical carcinoid tumors is unclear. Using a cohort including only these patients, we aimed to determine the impact of extent of lung resection and LN assessment on overall survival. METHODS: Patients undergoing lobectomy or sublobar resection for clinical stage T1aN0M0 intraparenchymal typical carcinoid tumor were identified in the National Cancer Data Base from 1998 to 2012...
November 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29106810/stereotactic-body-radiotherapy-for-early-stage-non-small-cell-lung-cancer-american-society-of-clinical-oncology-endorsement-of-the-american-society-for-radiation-oncology-evidence-based-guideline
#12
Bryan J Schneider, Megan E Daly, Erin B Kennedy, Mara B Antonoff, Stephen Broderick, Jill Feldman, Shruti Jolly, Bryan Meyers, Gaetano Rocco, Chad Rusthoven, Ben J Slotman, Daniel H Sterman, Brendon M Stiles
Purpose The American Society for Radiation Oncology (ASTRO) produced an evidence-based guideline on treatment with stereotactic body radiotherapy (SBRT) for patients with early-stage non-small-cell lung cancer. ASCO has a policy and set of procedures for endorsing and/or adapting clinical practice guidelines that have been developed by other professional organizations. Methods The ASTRO Evidence-Based Guideline for Stereotactic Body Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer was reviewed for developmental rigor by methodologists...
November 6, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29078696/vats-segmentectomy-an-underused-option
#13
REVIEW
Paolo Mendogni, Davide Tosi, Lorenzo Rosso, Alessandro Palleschi, Margherita Cattaneo, Alessandra Mazzucco, Mario Nosotti
It is well known that the "gold standard" procedure for surgically resectable early-stage non-small cell lung cancer (NSCLC), is pulmonary lobectomy. Even though sublobar resections (SLR), particularly segmentectomy, seem attractive as an alternative to lobectomy in early stage lung cancers, they are still debated procedures. The aim of this study is to answer to the question: "Is VATS lung segmentectomy an underused option?" To obtain an answer to this query, the authors carried out a review of the "state of the art" as follows: (I) performing a non-systematic review of the literature; (II) analyzing the review articles published; (III) looking at the ongoing studies, the results of which have not yet published; (IV) scanning the technical aspect of lung segmentectomy...
2017: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/28972833/management-of-patients-with-stage-i-lung-cancer
#14
Jeffrey A Bogart, Jason Wallen
The treatment of stage I non-small-cell lung cancer has advanced markedly over the past century. The transition from therapeutic nihilism with ensured mortality to radical surgery with pneumonectomy to rational oncologic-based resection has resulted in dramatically improved outcomes and reduced morbidity. The superiority of anatomic resection with lobectomy over sublobar resection for fit patients with stage I disease, where more than one half of all patients should expect to be cured, is backed by level 1 evidence...
February 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28969898/unplanned-procedures-during-thoracoscopic-segmentectomies
#15
Dominique Gossot, Jon Andri Lutz, Madalina Grigoroiu, Emmanuel Brian, Agathe Seguin-Givelet
BACKGROUND: Thoracoscopic sublobar resections (TSLRs) are gaining popularity, but are challenging. However, despite technical difficulties, the reported rate of adverse events, complications, and unplanned procedures is low. To understand this paradox, we have studied our series of TSLRs. METHODS: We reviewed our prospective and intention-to-treat database on videothoracoscopic anatomical resections and extracted all planned thoracoscopic segmentectomies from January 2007 to July 2016...
November 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28967802/current-evidence-does-not-warrant-frozen-section-evaluation-for-the-presence-of-tumor-spread-through-alveolar-spaces
#16
Ann E Walts, Alberto M Marchevsky
CONTEXT: - Tumor spread through alveolar spaces (STAS) has been correlated with unfavorable prognosis in lung adenocarcinomas treated with sublobar resection, but it is unknown whether STAS can be reliably identified in frozen section (FS) to help stratify patients for lobectomy or sublobar resection. OBJECTIVE: - To evaluate STAS in FS. DESIGN: - Tumor spread through alveolar spaces was evaluated in hematoxylin-eosin-stained FS, FS control slides, and all additional slides with lung tissue adjacent to tumor (AdLT) from 48 pT1-2 adenocarcinomas operated on using video-assisted thoracotomy (n = 25) or open thoracotomy (n = 23)...
January 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28958068/postoperative-complications-and-prognosis-after-lobar-resection-versus-sublobar-resection-in-elderly-patients-with-clinical-stage-i-non-small-cell-lung-cancer
#17
Yasuhiro Tsutani, Norifumi Tsubokawa, Masaoki Ito, Keizo Misumi, Hideaki Hanaki, Yoshihiro Miyata, Morihito Okada
OBJECTIVES: The study aimed to investigate the outcomes of sublobar resection in elderly patients with non-small-cell lung cancer. METHODS: A total of 205 patients aged ≥75 years were identified from 794 consecutive patients who underwent complete surgical resection for clinical Stage I non-small-cell lung cancer. The outcomes of lobectomy and sublobar resection were compared. Propensity scores were estimated for multivariable analyses and matching. RESULTS: Sublobar resection ( n  = 99) was more frequently performed than lobectomy ( n  = 106) in older patients ( P  = 0...
September 6, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28951090/improved-survival-of-stage-i-non-small-cell-lung-cancer-a-va-central-cancer-registry-analysis
#18
Matthew J Boyer, Christina D Williams, David H Harpole, Mark W Onaitis, Michael J Kelley, Joseph K Salama
INTRODUCTION: The combined impact of advances in diagnosis and treatment of stage I NSCLC has not been assessed comprehensively. To define the survival impact of modern staging and treatment techniques for clinical stage I NSCLC, the Veterans Administration Central Cancer Registry, a database of U.S. veterans in whom the disease was diagnosed in the Veteran's Health Administration, was queried. From this database, patients who had stage I NSCLC diagnosed from 2001 to 2010 and were treated with either surgery or radiation were identified...
December 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28819775/sublobar-resection-versus-lobectomy-in-patients-aged-%C3%A2-35%C3%A2-years-with-stage-ia-non-small-cell-lung-cancer-a-seer-database-analysis
#19
COMPARATIVE STUDY
Chang Gu, Rui Wang, Xufeng Pan, Qingyuan Huang, Yangyang Zhang, Jun Yang, Jianxin Shi
PURPOSE: Sublobar resection has been increasingly adopted in elderly patients with stage IA non-small cell lung cancer (NSCLC), but the equivalency of sublobar resection versus lobectomy among young patients with stage IA NSCLC is unknown. METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) registry, we identified patients aged ≤35 years who were diagnosed between 2004 and 2013 with pathological stage IA NSCLC and treated with sublobar resection or lobectomy...
November 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28781098/recent-advances-in-surgical-management-of-early-lung-cancer
#20
REVIEW
Shun-Mao Yang, Hsao-Hsun Hsu, Jin-Shing Chen
The broad application of low-dose computed tomography screening has resulted in the detection of many more cases of early lung cancer than ever before in modern history. Recent advances in the management of early-stage non-small cell lung cancer have focused on making therapy less traumatic, enhancing recovery, and preserving lung function. In this review, we discuss several new modalities associated with minimally invasive surgery for lung cancer. Firstly, less lung parenchyma resection via sublobar resection has become an acceptable alternative to lobectomy in patients with tumors less than 2 cm in size or with poor cardiopulmonary reserve...
August 3, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
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