Yinghui Hao, Fangmei Xie, Jieyi He, Chenqiong Gu, Ying Zhao, Wenfeng Luo, Xiaoyu Song, Jian Shen, Li Yu, Zeping Han, Jinhua He
Previous studies have shown that phenyllactic acid (alpha-Hydroxyhydrocinnamic acid, 2-Hydroxy-3-phenylpropionic acid, PLA), a type of organic acid metabolite, has excellent diagnostic efficacy when used to differentiate between prostate cancer, benign prostatic hyperplasia, and prostatitis. This research aims to explore the molecular mechanism by which PLA influences the PANoptosis of prostate cancer (PCa) cell lines. First, we found that PLA was detected in all prostate cancer cell lines (PC-3, PC-3M, DU145, LNCAP)...
February 24, 2024: International Journal of Biochemistry & Cell Biology