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https://www.readbyqxmd.com/read/28543984/cycle-affects-imidacloprid-efficiency-by-mediating-cytochrome-p450-expression-in-the-brown-planthopper-nilaparvata-lugens
#1
K Kang, P Yang, R Pang, L Yue, W Zhang
Circadian clocks influence most behaviours and physiological activities in animals, including daily fluctuations in metabolism. However, how the clock gene cycle influences insects' responses to pesticides has rarely been reported. Here, we provide evidence that cycle affects imidacloprid efficacy by mediating the expression of cytochrome P450 genes in the brown planthopper (BPH) Nilaparvata lugens, a serious insect pest of rice. Survival bioassays showed that the susceptibility of BPH adults to imidacloprid differed significantly between the two time points tested [Zeitgeber Time 8 (ZT8) and ZT4]...
May 23, 2017: Insect Molecular Biology
https://www.readbyqxmd.com/read/28540994/clinical-efficacy-and-safety-of-naftopidil-treatment-for-patients-with-benign-prostatic-hyperplasia-and-hypertension-a-prospective-open-label-study
#2
Mun Su Chung, Byung Il Yoon, Seung Hwan Lee
PURPOSE: To investigate the efficacy and safety of naftopidil for benign prostatic hyperplasia (BPH) patients, mainly focusing on changes in blood pressure (BP). MATERIALS AND METHODS: Of a total of 118 patients, 90 normotensive (NT) and 28 hypertensive (HT) patients were randomly assigned to be treated with naftopidil 50 mg or 75 mg for 12 weeks, once-daily. Safety and efficacy were assessed by analyzing changes from baseline in systolic/diastolic BP and total International Prostate Symptom Score (IPSS) at 4 and 12 weeks...
July 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28540239/the-impact-and-management-of-sexual-dysfunction-secondary-to-pharmacological-therapy-of-benign-prostatic-hyperplasia
#3
REVIEW
Jason Gandhi, Steven J Weissbart, Noel L Smith, Steven A Kaplan, Gautam Dagur, Anna Zumbo, Gargi Joshi, Sardar Ali Khan
Benign prostatic hyperplasia (BPH) is one of the most common genitourinary complications in men over 50 years of age and typically presents with lower urinary tract symptoms (LUTS). Classes of medications include α1-adrenoceptor blockers, 5α-reductase inhibitors, and phosphodiesterase 5 inhibitors. Today, α1-adrenoceptor blockers and 5α-reductase inhibitors are often combined to give a synergistic effect. A review of the current literature identified several adverse sexual side effects, including erectile dysfunction (ED), decreased libido, orgasmic disorders, and ejaculatory disorders...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28540231/use-of-botulinum-toxin-for-voiding-dysfunction
#4
REVIEW
David Eldred-Evans, Prokar Dasgupta
The use of botulinum toxin A (BoNT-A) has expanded across a range of lower urinary tract conditions. This review provides an overview of the current indications for BoNT-A in the lower urinary tract and critically evaluates the published evidence within each area. The classic application of BoNT-A has been in the management of refractory neurogenic detrusor overactivity (NDO) and overactive bladder (OAB). There is a large volume of high-quality evidence, including numerous randomized placebo-controlled trials, which demonstrate the efficacy of BoNT-A over a long follow-up period...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28532455/a-retrospective-study-of-treatment-persistence-and-adherence-to-%C3%AE-blocker-plus-antimuscarinic-combination-therapies-in-men-with-luts-bph-in-the-netherlands
#5
Marcus J Drake, Sally Bowditch, Emilio Arbe, Zalmai Hakimi, Florent Guelfucci, Ikbel Amri, Jameel Nazir
BACKGROUND: To assess treatment persistence and adherence in men ≥45 years of age with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), using prescription records from the Netherlands IMS Lifelink™ LRx database. METHODS: In this retrospective, observational cohort study, we identified men who received combination therapy with an α-blocker plus an antimuscarinic (e.g. solifenacin or tolterodine) between 1 November 2013 and 31 October 2014...
May 22, 2017: BMC Urology
https://www.readbyqxmd.com/read/28532232/a-two-week-double-blind-placebo-controlled-trial-of-viola-odorata-echium-amoenum-and-physalis-alkekengi-mixture-in-symptomatic-benign-prostate-hyperplasia-bph-men
#6
Fatemeh Beiraghdar, Behzad Einollahi, Alireza Ghadyani, Yunes Panahi, Abbas Hadjiakhoondi, Mahdi Vazirian, Ali Salarytabar, Behrad Darvishi
CONTEXT: As an alternative approach, administration of phytotherapeutic agents in management of benign prostate hyperplasia (BPH), is rapidly growing each day. Different authors have indicated effectiveness of Viola odorata L. (Violaceae), Echium amoenum Fisch. & C.A.Mey. (Boraginaceae) and Physalis alkekengi L. (Solanaceae) in treatment of BPH. However, none have reported the beneficial outcomes of the mixture yet. OBJECTIVE: This study evaluates the therapeutical effects of V...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28506862/a-relevant-mid-term-12-months-placebo-effect-on-lower-urinary-tract-symptoms-and-maximum-flow-rate-in-male-luts-bph-a-meta-analysis
#7
Klaus Eredics, Stephan Madersbacher, Ingrid Schauer
OBJECTIVE: To assess the mid- to long-term placebo effect of medical and instrumental management of male lower urinary tract symptoms (LUTS). This is - generally - a long-term treatment strategy. Therefore, knowledge on the mid- to long-term placebo effect is of considerable interest. The paucity of data on this topic prompted us to investigate this issue in a meta-analysis. METHODS: All randomized controlled trials (RCTs) with the indication BPH/LUTS containing a placebo- or sham treatment arm and with a follow-up of 12 months were eligible...
May 12, 2017: Urology
https://www.readbyqxmd.com/read/28506701/case-control-study-of-intraarterial-verapamil-for-intraprostatic-anastomoses-to-extraprostatic-arteries-in-prostatic-artery-embolization-for-benign-prostatic-hypertrophy
#8
Simon Chun Ho Yu, Carmen Cho, Esther Hung, Defeng Wang, Peter Chiu, Chi Hang Yee, Anthony Ng
PURPOSE: It is hypothesized that intraarterial administration of verapamil is a safe and effective way to reverse the flow in intraprostatic anastomoses to extraprostatic arteries without compromising treatment outcomes in prostatic artery embolization (PAE) for benign prostatic hypertrophy (BPH). MATERIALS AND METHODS: A prospective study of 62 prostate sides in 31 consecutive patients (median age, 66 y; range, 60-71 y) with symptomatic BPH was undertaken. Median prostate volume was 72...
May 13, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28503148/management-of-benign-prostatic-hyperplasia-could-dietary-polyphenols-be-an-alternative-to-existing-therapies
#9
REVIEW
Chinedum Eleazu, Kate Eleazu, Winner Kalu
The incidence of benign prostatic hyperplasia (BPH) is gradually on the increase. While conventional drugs such as the α1-adrenergic receptor antagonists and 5α-reductase inhibitors have been found to be useful in the treatment of BPH, the adverse side effects associated with their usage, have led to increased search for alternative means of managing this disease. Furthermore, although surgery has also been suggested to be a sure method, the cost and risks associated with it excludes it as a routine treatment...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28502962/treatment-results-of-transurethral-resection-of-the-prostate-by-non-japanese-board-certified-urologists-for-benign-prostate-hyperplasia-analysis-by-resection-volume
#10
Yasutomo Suzuki, Yuka Toyama, Satoko Nakayama, Shunichiro Nomura, Tadaaki Minowa, Kuniaki Tanabe, Yukihiro Kondo
INTRODUCTION: Transurethral resection of the prostate (TURP) is the gold standard for surgical treatment of benign prostatic hyperplasia (BPH), but it has complications such as bleeding and transurethral resection syndrome. The treatment results of TURP performed by non-Japanese board-certified urologists were examined, and the results were analyzed according to the resection volume to determine how much resection volume was suitable for non-Japanese board-certified urologists. MATERIALS AND METHODS: A total of 72 cases that underwent TURP for BPH at our hospital were examined...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28495071/perioperative-and-economic-analysis-of-surgical-treatments-for-benign-prostatic-hyperplasia-a-study-of-the-french-committee-on-lut
#11
R Mathieu, S Lebdai, J N Cornu, A Benchikh, A R Azzouzi, N B Delongchamps, O Dumonceau, A Faix, M Fourmarier, O Haillot, B Lukacs, V Misrai, A de La Taille, G Robert, A Descazeaud
PURPOSE: To evaluate perioperative cost related to surgical treatments of benign prostatic obstruction (BPO): photoselective vaporization of the prostate (pvp), holmium/thullium laser enucleation (HoLEP/ThuLEP), transurethral resection of the prostate (TURP) and open prostatectomy (OP). MATERIAL AND METHODS: We retrospectively collected data from 237 patients who consecutively underwent a surgical treatment for BPH between January 2012 and June 2013 at nine institutions in France...
May 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28493523/fibrillar-collagen-genes-are-not-co-ordinately-up-regulated-with-tgf-%C3%AE-1-expression-in-finasteride-treated-prostate
#12
Flávia Karina Delella, Fernanda Losi Alves de Almeida, Helga Caputo Nunes, Jaqueline Carvalho Rinaldi, Sérgio Luis Felisbino
Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptoms (LUTS) in older men. In this regard, recent studies have attempted to define the relationships between prostatic fibrosis, LUTS, and increased expression of transforming growth factor β1 (TGF β1) in BHP. Therapeutic approaches for BPH such as 5-α-reductase inhibitors and alpha-adrenergic blocking agents increase TGF β1 expression in the prostatic tissue. Here, we investigated the effects of the 5-α-reductase inhibitor-finasteride-on rat ventral prostate tissue, especially with regard to the tissue distribution and gene expression of fibrillar collagens...
May 11, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28491852/a-case-of-recurrent-hematuria-in-primary-prostatic-low-grade-mucosa-associated-lymphoid-tissue
#13
Saeed Hashemzadeh, Farid Farrokhi, Amir Hozhabrossadaty, Kamran Ghafarzadegan, Hami Ashraf
BACKGROUND: Primary mucosa-associated lymphoid tissue (MALT) lymphoma is a rare malignancy. We found only 8 cases of MALT lymphoma in literature. CASE PRESENTATION: We report here another case of primary prostatic MALT lymphoma which is presented by hematuria and diagnosed primarily as BPH. Immunohistochemistry studies demonstrate the diagnosis and MALT lymphoma. Six months after starting the treatment the patient was alive and well. CONCLUSIONS: Prostatic MALTomas are mainly presented with urinary obstruction or hematuria and have an indolent growth with a good prognosis...
March 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28490907/perspective-on-the-rez%C3%A5-m-%C3%A2-system-a-minimally-invasive-treatment-strategy-for-benign-prostatic-hyperplasia-using-convective-radiofrequency-water-vapor-thermal-therapy
#14
Henry H Woo, Ricardo R Gonzalez
Convective radiofrequency (RF) water vapor thermal therapy is a minimally invasive office or outpatient procedure for the treatment of bothersome moderate-to-severe lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It provides an option for patients seeking rapid and durable relief of urinary symptoms, improved quality of life, and preservation of sexual function as an alternative to long-term use of drugs and avoidance of the potential side effects of pharmaceuticals or invasive BPH surgery...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28487578/5%C3%AE-reductase-inhibitors-for-treatment-of-benign-prostatic-hyperplasia-a-systematic-review-and-meta-analysis
#15
REVIEW
Jennifer E J Jun, Angus Kinkade, Anthony C H Tung, Aaron M Tejani
BACKGROUND: Finasteride and dutasteride are competitive inhibitors of 5α-reductase enzymes and are commonly used to treat symptomatic benign prostatic hyperplasia (BPH). OBJECTIVE: To compare the efficacy and safety of finasteride and dutasteride in terms of clinically important outcomes. DATA SOURCES: A literature search was performed using the search terms "prostatic hyperplasia", "prostatic hypertrophy", "dutasteride", "finasteride", "quality of life", "adverse drug reaction", and "mortality"...
March 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28484937/effects-of-ganoderma-lucidum-shell-broken-spore-on-oxidative-stress-of-the-rabbit-urinary-bladder-using-an-in-vivo-model-of-ischemia-reperfusion
#16
Robert M Levin, Li Xia, Wu Wei, Catherine Schuler, Robert E Leggett, Alpha D-Y Lin
Oxidative stress plays an important role in specific disease pathophysiology and the aging process. In the history of human kind, many herbs were utilized for disease prevention and anti-aging treatment. However, there are few direct evidences provided by modern laboratory technology. The current study was designed to evaluate Ganoderma Lucidum's (GL) ability to reduce the damage from in vivo ischemia/reperfusion (I/R) using a rabbit model of I/R that has been effectively utilized to prove the effects of drugs and supplements to reduce oxidative stress...
May 8, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28483481/-outcomes-of-greenlight-xps-180w-laser-photovaporization-for-bph-larger-than-80ml
#17
M Thoulouzan, M-A Perrouin-Verbe, J Calves, C Deruelle, V Joulin, A Valeri, G Fournier
AIM: To evaluate the results of GreenLight XPS photovaporization (PVP/XPS) with intraoperative transrectal ultrasonographic monitoring for the treatment of large Benign Prostatic Hyperplasia (BPH) (>80mL). PATIENTS AND METHODS: Operative and perioperative data of 82 patients were collected prospectively. Complications and functional outcomes (IPSS, quality of life (QoL) score, maximal flow rate and post-void residual (PVR)) were evaluated at 1, 3, 12 months post-operatively prostate volume and PSA were assessed at 3 and 12 months post-operatively...
May 5, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28474611/patient-reported-ejaculatory-function-and-satisfaction-in-men-with-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#18
Min Chul Cho, Jung Kwon Kim, Sang Hoon Song, Sung Yong Cho, Sang Wook Lee, Soo Woong Kim, Jae-Seung Paick
This study aimed to investigate perceived ejaculatory function/satisfaction before treatment for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) and to identify associations between specific categories of ejaculatory dysfunctions (EjDs) and LUTS. A total of 1574 treatment-naïve men with LUTS/BPH were included in this study. All patients underwent routine evaluation for LUTS/BPH including the International Index of Erectile Function and a 5-item questionnaire developed to assess ejaculatory volume/force/pain/satisfaction/latency time...
May 2, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28474112/transperineal-laser-ablation-for-percutaneous-treatment-of-benign-prostatic-hyperplasia-a-feasibility-study
#19
Gianluigi Patelli, Antonio Ranieri, Aurelio Paganelli, Giovanni Mauri, Claudio Maurizio Pacella
PURPOSE: To assess the feasibility and safety of transperineal laser ablation (TPLA) for treating benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Institutional review board approval was obtained for this prospective non-randomized trial. Eightteen patients (age 71.7 ± 9.4 years) with urinary symptoms secondary to BPH underwent TPLA under local anesthesia. Under US guidance, up to four 21G applicators were inserted in the prostatic tissue. Each treatment was performed with diode laser operating at 1064 nm changing the illumination time according to prostate size...
May 4, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28455944/patterns-of-medical-management-of-overactive-bladder-oab-and-benign-prostatic-hyperplasia-bph-in-the-united-states
#20
Jennifer T Anger, Howard B Goldman, Xuemei Luo, Martin O Carlsson, Douglass Chapman, Kelly H Zou, David Russell, Fady Ntanios, Canan B Esinduy, J Quentin Clemens
AIMS: Overactive bladder (OAB) and benign prostatic hyperplasia (BPH) are highly prevalent conditions that place a large burden on the United States (US) health care system. We sought to analyze patterns of prescription medication usage for incident OAB in men and women, and for incident BPH in men using US health insurance claims data. MATERIALS AND METHODS: This study used Truven Health MarketScan® Commercial and Medicare Supplemental Research databases. The data were pooled from diverse points of care...
April 28, 2017: Neurourology and Urodynamics
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