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https://www.readbyqxmd.com/read/29454864/inactivation-of-escherichia-coli-and-staphylococcus-aureus-on-contaminated-perilla-leaves-by-dielectric-barrier-discharge-dbd-plasma-treatment
#1
Sang Hye Ji, Se Hoon Ki, Ji Ho Ahn, Jae Ho Shin, Eun Jeong Hong, Yun Ji Kim, Eun Ha Choi
This study focused on sterilization methods for the reduction of microorganisms on perilla leaves by cylinder type Dielectric Barrier Discharge (DBD) plasma with underwater bubbler treatment. S. aureus and E. coli in a suspension were reduced to less than 3.4 and 0.5 log CFU/ml after the plasma treatment for 3 min, respectively. On the perilla leaves, they were also reduced to 4.8 and 1.6 log CFU/ml after the plasma treatment, respectively. The S. aureus and E. coli bacterial cell wall was damaged by the plasma treatment evident by scanning electron microscopic analysis...
February 15, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29399293/anti-hyperglycemic-effects-and-signaling-mechanism-of-perilla-frutescens-sprout-extract
#2
Da-Hye Kim, Sang Jun Kim, Kang-Yeol Yu, Seung-Il Jeong, Seon-Young Kim
BACKGROUND/OBJECTIVES: Perilla frutescens (L.) Britton var. (PF) sprout is a plant of the labiate family. We have previously reported the protective effects of PF sprout extract on cytokine-induced β-cell damage. However, the mechanism of action of the PF sprout extract in type 2 diabetes (T2DM) has not been investigated. The present study was designed to study the effects of PF sprout extract and signaling mechanisms in the T2DM mice model using C57BL/KsJ-db/db (db/db) mice. MATERIALS/METHODS: Male db/db mice were orally administered PF sprout extract (100, 300, and 1,000 mg/kg of body weight) or rosiglitazone (RGZ, positive drug, 1 mg/kg of body weight) for 4 weeks...
February 2018: Nutrition Research and Practice
https://www.readbyqxmd.com/read/29371082/feasibility-of-using-a-bacteriophage-based-structural-color-sensor-for-screening-the-geographical-origins-of-agricultural-products
#3
Daun Seol, Jong-Sik Moon, Yujin Lee, Jiye Han, Daeil Jang, Dong-Jin Kang, Jiyoung Moon, Eunjin Jang, Jin-Woo Oh, Hoeil Chung
An M13 bacteriophage-based color sensor, which can change its structural color upon interaction with a gaseous molecule, was evaluated as a screening tool for the discrimination of the geographical origins of three different agricultural products (garlic, onion, and perilla). Exposure of the color sensor to sample odors induced the self-assembled M13 bacteriophage bundles to swell by the interaction of amino acid residues (repeating units of four glutamates) on the bacteriophage with the odor components, resulting in a change in the structural color of the sensor...
January 5, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29351555/omega-3-fatty-acid-desaturase-gene-family-from-two-%C3%AF-3-sources-salvia-hispanica-and-perilla-frutescens-cloning-characterization-and-expression
#4
Yufei Xue, Baojun Chen, Aung Naing Win, Chun Fu, Jianping Lian, Xue Liu, Rui Wang, Xingcui Zhang, Yourong Chai
Omega-3 fatty acid desaturase (ω-3 FAD, D15D) is a key enzyme for α-linolenic acid (ALA) biosynthesis. Both chia (Salvia hispanica) and perilla (Perilla frutescens) contain high levels of ALA in seeds. In this study, the ω-3 FAD gene family was systematically and comparatively cloned from chia and perilla. Perilla FAD3, FAD7, FAD8 and chia FAD7 are encoded by single-copy (but heterozygous) genes, while chia FAD3 is encoded by 2 distinct genes. Only 1 chia FAD8 sequence was isolated. In these genes, there are 1 to 6 transcription start sites, 1 to 8 poly(A) tailing sites, and 7 introns...
2018: PloS One
https://www.readbyqxmd.com/read/29331904/anthocyanins-in-perilla-plants-and-dried-leaves
#5
Yumi Fujiwara, Miya Kono, Airi Ito, Michiho Ito
High-quality perilla leaves are purple on upper and lower surfaces and have a good aroma. The Japanese Pharmacopoeia specifies the content of essential oils in perilla leaves but not that of anthocyanins. Several reports have described the chemical species of anthocyanins in red perilla, but a complete analysis of anthocyanins in perilla has not been reported. In this study, the anthocyanins in the leaves of cultivated and wild species of perilla and those in commercially available perilla herbs were studied...
January 11, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29331150/production-of-eicosapentaenoic-acid-by-application-of-a-delta-6-desaturase-with-the-highest-ala-catalytic-activity-in-algae
#6
Haisu Shi, Xue Luo, Rina Wu, Xiqing Yue
Dunaliella salina is a unicellular green alga with a high α-linolenic acid (ALA) level, but a low eicosapentaenoic acid (EPA) level. In a previous analysis of the catalytic activity of delta 6 fatty acid desaturase (FADS6) from various species, FADS6 from Thalassiosira pseudonana (TpFADS6), a marine diatom, showed the highest catalytic activity for ALA. In this study, to enhance EPA production in D. salina, FADS6 from D. salina (DsFADS6) was identified, and substrate specificities for DsFADS6 and TpFADS6 were characterized...
January 13, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29260378/%C3%AF-3-fatty-acid-synergized-novel-nanoemulsifying-system-for-rosuvastatin-delivery-in-vitro-and-in-vivo-evaluation
#7
Chandra Bhushan Tripathi, Neha Gupta, Pranesh Kumar, Ashok Kumar Singh, Vinit Raj, Poonam Parashar, Mahendra Singh, Jovita Kanoujia, Malti Arya, Shubhini A Saraf, Sudipta Saha
The present study was undertaken to improve rosuvastatin (RSV) bioavailability and pharmacological response through formation of SNES using Perilla frutescens oil as lipid carrier. The composition of oil was estimated by fatty acid methyl ester (FAME) analysis using gas chromatography. Solubility of RSV in Perilla frutescens oil and Cremophor EL was 25.0 ± 3.0 and 60.0 ± 5.0 mg/mL, respectively. Later, nanophasic maps and a central composite design were employed to determine the maximum nanoemulsion region and further optimize SNES in this study...
December 19, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/29248943/edentulism-and-its-relationship-with-self-rated-health-secondary-analysis-of-the-sabe-ecuador-2009-study
#8
Miguel Germán Borda, Nicolás Castellanos-Perilla, Judy Andrea Patiño, Sandra Castelblanco, Carlos Alberto Cano, Diego Chavarro-Carvajal, Mario U Pérez-Zepeda
Edentulism is related to a number of conditions in older adults, impacting their overall health status and thus their quality of life and relationship with the environment. At the same time, self-rated health has been shown to be an accurate marker of overall health status. However there is little information on how edentulism relates to self-rated health in older adults of Hispanic origin. The aim of this study was to evaluate the impact of edentulism on self-rated health in older adults. We analyzed data from SABE Ecuador 2009, a cross-sectional study that included a probabilistic representative sample of 5, 235 community-dwelling older adults aged 60 years or older...
August 2017: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/29248449/interactions-between-crude-drug-extracts-used-in-japanese-traditional-kampo-medicines-and-organic-anion-transporting-polypeptide-2b1
#9
Rie Iijima, Tomoki Watanabe, Kan'ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
ETHNOPHARMACOLOGICAL RELEVANCE: The use of herbal medicines has become popular worldwide, and the information on drug interactions between herbal medicines and chemical drugs is needed. AIM OF THE STUDY: We screened the inhibitory effects of crude drugs used in Kampo medicines used in Japan on organic anion-transporting polypeptide (OATP) 2B1 to predict potential interactions between Kampo medicines and chemical drugs used together. MATERIALS AND METHODS: We chose 98 kinds of crude drugs frequently used as ingredients of Kampo formulations in Japan and prepared their boiling water extracts...
December 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29246281/%C3%AE-lipoic-acid-ameliorated-oxidative-stress-induced-by-perilla-oil-but-the-combination-of-these-dietary-factors-was-ineffective-to-cause-marked-deceases-in-serum-lipid-levels-in-rats
#10
Takashi Ide, Ai Tanaka
Dietary perilla oil rich in α-linolenic acid and α-lipoic acid lowers the serum lipid level through changes in hepatic fatty acid metabolism. We therefore hypothesized that the combination of these dietary factors may ameliorate lipid metabolism more than the factors individually. Moreover, α-lipoic acid exerts strong anti-oxidative activity. Hence, we also hypothesized that α-lipoic acid may attenuate perilla oil-mediated oxidative stress. We therefore studied the combined effects of perilla oil and α-lipoic acid on lipid metabolism and parameters of oxidative stress...
December 2017: Nutrition Research
https://www.readbyqxmd.com/read/29239729/corrigendum-to-anti-inflammatory-effects-of-perillae-herba-ethanolic-extract-against-tnf-%C3%AE-ifn-%C3%AE-stimulated-human-keratinocyte-hacat-cells-j-ethnopharmacol-211-2018-217-223
#11
Ju-Hye Yang, Jae-Myung Yoo, Esther Lee, BoHyoung Lee, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma
No abstract text is available yet for this article.
November 24, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29197368/an-asian-traditional-herbal-complex-containing-houttuynia-cordata-thunb-perilla-frutescens-var-acuta-and-green-tea-stimulates-hair-growth-in-mice
#12
Mun Su Chung, Woong Jin Bae, Sae Woong Choi, Kyu Won Lee, Hyun Cheoul Jeong, Fahad Bashraheel, Seung Hwan Jeon, Jin Woo Jung, Byung Il Yoon, Eun Bi Kwon, Hyun A Oh, Sung Yeoun Hwang, Sae Woong Kim
BACKGROUND: Houttuynia cordata Thunb (HC) is a traditional herbal medicine widely used in Asia for the treatment of patients with alopecia, usually in combination with other two herbal medicines (Perilla frutescens var. acuta (PFVA) and green tea (GT)). However, the effect of this herbal complex has not been clearly demonstrated. We sought to determine the hair growth-promoting effect of this herbal complex (HC, PFVA, and GT) in the animal model. METHODS: Six-week-old male C57BL/6 mice were randomly divided into four groups (negative control, finasteride (1 mg/kg) as a positive control, and two (200 and 400 mg/kg) concentrations of the herbal complex as experimental groups) and were fed its corresponding medications orally for 25 days...
December 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29176596/quenching-protein-dynamics-interferes-with-hiv-capsid-maturation
#13
Mingzhang Wang, Caitlin M Quinn, Juan R Perilla, Huilan Zhang, Randall Shirra, Guangjin Hou, In-Ja Byeon, Christopher L Suiter, Sherimay Ablan, Emiko Urano, Theodore J Nitz, Christopher Aiken, Eric O Freed, Peijun Zhang, Klaus Schulten, Angela M Gronenborn, Tatyana Polenova
Maturation of HIV-1 particles encompasses a complex morphological transformation of Gag via an orchestrated series of proteolytic cleavage events. A longstanding question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA-SP1), which represents an intermediate during maturation of the HIV-1 virus. By integrating NMR, cryo-EM, and molecular dynamics simulations, we show that in CA-SP1 tubes assembled in vitro, which represent the features of an intermediate assembly state during maturation, the SP1 peptide exists in a dynamic helix-coil equilibrium, and that the addition of the maturation inhibitors Bevirimat and DFH-055 causes stabilization of a helical form of SP1...
November 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/29144390/rna-sequencing-and-coexpression-analysis-reveal-key-genes-involved-in-%C3%AE-linolenic-acid-biosynthesis-in-perilla-frutescens-seed
#14
Tianyuan Zhang, Chi Song, Li Song, Zhiwei Shang, Sen Yang, Dong Zhang, Wei Sun, Qi Shen, Degang Zhao
Perillafrutescen is used as traditional food and medicine in East Asia. Its seeds contain high levels of α-linolenic acid (ALA), which is important for health, but is scarce in our daily meals. Previous reports on RNA-seq of perilla seed had identified fatty acid (FA) and triacylglycerol (TAG) synthesis genes, but the underlying mechanism of ALA biosynthesis and its regulation still need to be further explored. So we conducted Illumina RNA-sequencing in seven temporal developmental stages of perilla seeds...
November 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29122738/performance-of-a-mobile-phone-app-based-participatory-syndromic-surveillance-system-for-acute-febrile-illness-and-acute-gastroenteritis-in-rural-guatemala
#15
Daniel Olson, Molly Lamb, Maria Renee Lopez, Kathryn Colborn, Alejandra Paniagua-Avila, Alma Zacarias, Ricardo Zambrano-Perilla, Sergio Ricardo Rodríguez-Castro, Celia Cordon-Rosales, Edwin Jose Asturias
BACKGROUND: With their increasing availability in resource-limited settings, mobile phones may provide an important tool for participatory syndromic surveillance, in which users provide symptom data directly into a centralized database. OBJECTIVE: We studied the performance of a mobile phone app-based participatory syndromic surveillance system for collecting syndromic data (acute febrile illness and acute gastroenteritis) to detect dengue virus and norovirus on a cohort of children living in a low-resource and rural area of Guatemala...
November 9, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29119654/carcass-traits-meat-quality-antioxidant-status-and-antioxidant-gene-expression-in-muscle-and-liver-of-hu-lambs-fed-perilla-seed
#16
K P Deng, Y X Fan, T W Ma, Z Wang, W J TanTai, H T Nie, Y X Guo, X Q Yu, L W Sun, F Wang
The effects of perilla (Perilla frutescens L.) seed on carcass traits, meat quality, antioxidant status and antioxidant gene expression in the liver and muscle of Hu lambs were investigated in this study. Sixty Hu lambs (23.02 ± 1.36 kg) were randomly divided into four experimental groups receiving diets containing 0%, 5%, 10% or 15% perilla seed (CD, 5%PFSD, 10%PFSD and 15%PFSD, respectively). The addition of perilla seed had no significant impacts on carcass traits (p > .05). There were no differences in pH, meat colour, drip loss, cooking loss or shear force among the four treatments (p > ...
November 9, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29110743/rosmarinic-acid-modes-of-action-medicinal-values-and-health-benefits
#17
Mahmoud Alagawany, Mohamed Ezzat Abd El-Hack, Mayada Ragab Farag, Marappan Gopi, Kumaragurubaran Karthik, Yashpal Singh Malik, Kuldeep Dhama
The supplementation of livestock rations with herbs containing bioactive components, such as rosmarinic acid (RA), have shown promising results as a natural feed additive in promoting growth, productive and reproductive performance, feed utilization, fertility, anti-oxidant status and immunologic indices. Furthermore, RA reportedly reduces the risks of various animal diseases and mitigates side effects of chemical and synthetic drugs. RA is a natural polyphenol present in several Lamiaceae herbs like Perilla frutescens, and RA is becoming an integral component of animal nutrition as it counters the effect of reactive oxygen species induced in the body as a consequence of different kinds of stressors...
November 7, 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/29092397/alpha-linolenic-acid-from-perilla-frutescens-var-japonica-oil-protects-a%C3%AE-induced-cognitive-impairment-through-regulation-of-app-processing-and-a%C3%AE-degradation
#18
Ah Young Lee, Myoung Hee Lee, Sanghyun Lee, Eun Ju Cho
Alzheimer's disease (AD) is characterized by progressive cognitive and memory impairment. The major pathological hallmark of AD is the accumulation of amyloid beta (Aβ), which is produced from the amyloid precursor protein (APP) through cleavage of β- and γ-secretase. Recently, dietary plant oil containing ω-3 polyunsaturated fatty acid has become attractive alternative sources to fish oil containing eicosapentaenoic acid or docosahexaenoic acid (DHA). We investigated whether ALA isolated from perilla oil has direct effects on improvement of cognitive ability and molecular mechanisms in APP processing in comparison with DHA...
November 2, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29082687/-medicinal-plant-dna-marker-assisted-breeding-%C3%A2-the-assistant-identification-of-snps-assisted-identification-and-breeding-research-of-high-yield-perilla-frutescens-new-variety
#19
Qi Shen, Dong Zhang, Wei Sun, Yu-Jun Zhang, Zhi-Wei Shang, Shi-Lin Chen
Perilla frutescens is one of 60 kinds of food and medicine plants in the initial directory announced by health ministry of China. With the development of Perilla domain in recent , the breeding and application of good varieties has become the main bottleneck of its development. This study reported that applied to the system selection, add to marker-assisted method to breed perilla varieties. Through the whole genome sequencing and consistency matching, annotated the mutation locus according to genome data, and comparison analysis with Perilla common variants database, finally selected 30 non-synonymous mutation SNPs used as characteristic markers of Zhongyan Feishu No...
May 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29027425/-morphological-characteristics-of-chinese-perilla-fruits
#20
Chen-Wu Zhang, Chang-Ling Wei, Fen Zhang, Jing Tian, An-Jia Chen, Bao-Lin Guo
The morphological traits of 55 Chinese Perilla fruit samples (size, 100 grains weight, color, hardness, surface ridge height) are described and the statistically analyzed. It can be divided into 6 categories by cluster analysis, namely: Ⅰ, big grain (diameter 1.5 mm above and 100 grains weight above 0.16 g), low ridge, hard; Ⅱ, big grain, low ridge, soft; Ⅲ, big grain, high ridge, soft, fruit; Ⅳ, big grain. high ridge, gray brown or dark brown; Ⅴ, small grain (diameter 1.5 mm below and 100 grain weight 0...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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