keyword
MENU ▼
Read by QxMD icon Read
search

oncologic outcome

keyword
https://www.readbyqxmd.com/read/29667344/concise-review-aggressive-colorectal-cancer-role-of-epithelial-cell-adhesion-molecule-in-cancer-stem-cells-and-epithelial-to-mesenchymal-transition
#1
REVIEW
Maximilian Boesch, Gilbert Spizzo, Andreas Seeber
Colorectal cancer (CRC) is one of the most common malignancies worldwide. In spite of various attempts to ameliorate outcome by escalating treatment, significant improvement is lacking particularly in the adjuvant setting. It has been proposed that cancer stem cells (CSCs) and the epithelial-to-mesenchymal transition (EMT) are at least partially responsible for therapy resistance in CRC. The epithelial cell adhesion molecule (EpCAM) was one of the first CSC antigens to be described. Furthermore, an EpCAM-specific antibody (edrecolomab) has the merit of having launched the era of monoclonal antibody treatment in oncology in the 1990s...
April 17, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29666808/oncological-outcomes-of-the-time-trial-in-esophageal-cancer-is-it-the-era-of-minimally-invasive-esophagectomy
#2
EDITORIAL
Lijie Tan, Han Tang
No abstract text is available yet for this article.
February 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29664841/three-year-recurrence-free-survival-in-patients-with-a-very-low-risk-of-endometrial-cancer-who-did-not-undergo-lymph-node-dissection-tree-retro-a-korean-multicenter-study
#3
Miseon Kim, ChelHun Choi, Kidong Kim, Myong Cheol Lim, Jeong-Yeol Park, Jin Hwa Hong, Maria Lee, Jiheum Paek, Jungyeob Seoung, Seungho Lee, Taek Sang Lee
OBJECTIVE: Randomized studies have not demonstrated a survival benefit of routine lymph node dissection in early-stage endometrial cancer. Many surgeons nevertheless perform lymph node dissection in all patients with early-stage endometrial cancer. This study aimed to ascertain the survival outcomes of very low-risk endometrial cancer patients (by the Korean Gynecologic Oncology Group [KGOG] criteria) who did not undergo lymph node dissection. MATERIALS AND METHODS: Medical records of 156 consecutive patients who underwent surgical staging without lymph node dissection were collected from 10 institutions...
April 16, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29664813/development-and-validation-of-nomograms-predicting-overall-and-cancer-specific-survival-of-spinal-chondrosarcoma-patients
#4
Kehan Song, Jian Song, Xio Shi, Hongli Wang, Xiaosheng Ma, Xinlei Xia, Xin Liang, Kaiyuan Lin, Jianyuan Jiang
STUDY DESIGN: Retrospective analysis. OBJECTIVE: To develop and validate nomograms to predict overall survival (OS) and cancer-specific survival (CSS) of spinal chondrosarcoma patients. SUMMARY OF BACKGROUND DATA: In this era of personalized medicine, data those are available to predict the survival of spinal chondrosarcoma patients are still limited due to the rarity of the disease. Nomogram, which has been widely used in clinical oncology, could conveniently and precisely predict survival outcome for individual patient...
April 16, 2018: Spine
https://www.readbyqxmd.com/read/29664697/best-practices-for-reducing-unplanned-acute-care-for-patients-with-cancer
#5
Nathan R Handley, Lynn M Schuchter, Justin E Bekelman
Variation and cost in oncology care represent a large and growing burden for the US health care system, and acute hospital care is one of the single largest drivers. Reduction of unplanned acute care is a major priority for clinical transformation in oncology; proposed changes to Medicare reimbursement for patients with cancer who suffer unplanned admissions while receiving chemotherapy heighten the need. We conducted a review of best practices to reduce unplanned acute care for patients with cancer. We searched PubMed for articles published between 2000 and 2017 and reviewed guidelines published by professional organizations...
April 17, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29664692/comparison-of-short-term-functional-oncological-and-perioperative-outcomes-between-laparoscopic-and-robotic-partial-nephrectomy-beyond-the-learning-curve
#6
Quentin Alimi, Benoit Peyronnet, Philippe Sebe, Jean-François Cote, Solene-Florence Kammerer-Jacquet, Zine-Eddine Khene, Benjamin Pradere, Romain Mathieu, Gregory Verhoest, Bertrand Guillonneau, Karim Bensalah
PURPOSE: To compare the short-term outcomes of robot-assisted partial nephrectomy (RPN) and laparoscopic partial nephrectomy (LPN) when performed by highly experienced surgeons. METHODS: A prospective multicenter study was conducted, including the 50 last patients having undergone LPN and RPN for T1-T2 renal tumors in two institutions between 2013 and 2016, performed by two different surgeons with an experience of over 200 procedures each in LPN and RPN, respectively, at the beginning of the study...
April 17, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29664243/new-technologies-and-techniques-for-prostate-cancer-focal-therapy-a-review-of-the-current-literature
#7
Estefanía Linares-Espinós, Arie Carneiro, Juan I Martínez-Salamanca, Fernando Bianco, Adalberto Castro-Alfaro, Xavier Cathelineau, Massimo Valerio, Rafael Sanchez-Salas
BACKGROUND: The aim of this study was to review the oncological and functional outcomes of new and established primary focal treatments (FT) for localized prostate cancer (PCa). METHODS: We performed a systematic search of published studies on FT for localized PCa using electronic databases (Medline and Embase). These studies included reports on hemiablation, focal ablation and target-ablation. We excluded salvage focal therapy studies and limited the search to those with a minimum of 12 months of follow-up...
April 16, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29663528/purely-off-clamp-robotic-partial-nephrectomy-preliminary-3-year-oncological-and-functional-outcomes
#8
Giuseppe Simone, Leonardo Misuraca, Gabriele Tuderti, Francesco Minisola, Mariaconsiglia Ferriero, Giuseppe Romeo, Manuela Costantini, Samer F Al-Rawashdah, Salvatore Guaglianone, Michele Gallucci
OBJECTIVES: To describe our surgical technique and to report perioperative, 3-year oncological and functional outcomes of a single-center series of purely off-clamp robotic partial nephrectomy. METHODS: A prospective renal cancer institutional database was queried, and data of consecutive patients treated with purely off-clamp robotic partial nephrectomy between 2010 and 2015 in a high-volume center were collected. Perioperative complications, and 3-year oncological and functional outcomes were assessed...
April 16, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29663303/abdominoperineal-resection-for-rectal-cancer-in-the-twenty-first-century-indications-techniques-and-outcomes
#9
Alexander T Hawkins, Katherine Albutt, Paul E Wise, Karim Alavi, Ranjan Sudan, Andreas M Kaiser, Liliana Bordeianou
BACKGROUND: Management of low rectal cancer continues to be a challenge, and decision making regarding the need for an abdominoperineal resection (APR) in patients with low-lying tumors is complicated. Furthermore, choices need to be made regarding need for modification of the surgical approach based on tumor anatomy and patient goals. DISCUSSION: In this article, we address patient selection, preoperative planning, and intraoperative technique required to perform the three types of abdominoperineal resections for rectal cancer: extrasphincteric, extralevator, and intersphincteric...
April 16, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29663302/multivisceral-resection-for-locally-advanced-gastric-and-gastroesophageal-junction-cancers-11-year-experience-at-a-high-volume-north-american-center
#10
J C Molina, A Al-Hinai, A Gosseling-Tardif, P Bouchard, J Spicer, D Mulder, C L Mueller, L E Ferri
INTRODUCTION: The oncologic benefit of multivisceral en bloc resections for T4 gastroesophageal tumors has been questioned, given the increased morbidity associated. We thus sought to investigate the surgical and oncologic outcomes of curative-intent en bloc multivisceral resections for T4 gastroesophageal carcinomas. METHODS: Between 2005 and 2016, 35 of the 525 patients who had gastric or EGJ carcinomas underwent curative-intent multivisceral resections for direct invasion or adhesion to adjacent organs...
April 16, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29662831/the-asia-pacific-consensus-statement-on-laparoscopic-liver-resection-for-hepatocellular-carcinoma-a-report-from-the-7th-asia-pacific-primary-liver-cancer-expert-meeting-held-in-hong-kong
#11
Tan To Cheung, Ho-Seong Han, Wong Hoi She, Kuo-Hsin Chen, Pierce K H Chow, Boon Koon Yoong, Kit Fai Lee, Shoji Kubo, Chung Ngai Tang, Go Wakabayashi
Background: Laparoscopic liver resection has been gaining momentum, and it has become an accepted practice after the two international consensus conferences where experts worked up guidelines to standardize this approach and improve its safety. However, most laparoscopic hepatectomies were performed in patients with liver metastases. The concurrent presence of liver cirrhosis with hepatocellular carcinoma (HCC) poses a great challenge to clinicians trying to establish a routine use of laparoscopic liver resection for HCC...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29662542/meta-analysis-of-studies-comparing-oncologic-outcomes-of-radical-prostatectomy-and-brachytherapy-for-localized-prostate-cancer
#12
Gabriele Cozzi, Gennaro Musi, Roberto Bianchi, Danilo Bottero, Antonio Brescia, Antonio Cioffi, Giovanni Cordima, Maurizio Delor, Ettore Di Trapani, Matteo Ferro, Deliu Victor Matei, Andrea Russo, Francesco Alessandro Mistretta, Ottavio De Cobelli
Background: The aim of this study was to compare oncologic outcomes of radical prostatectomy (RP) with brachytherapy (BT). Methods: A literature review was conducted according to the 'Preferred reporting items for systematic reviews and meta-analyses' (PRISMA) statement. We included studies reporting comparative oncologic outcomes of RP versus BT for localized prostate cancer (PCa). From each comparative study, we extracted the study design, the number and features of the included patients, and the oncologic outcomes expressed as all-cause mortality (ACM), PCa-specific mortality (PCSM) or, when the former were unavailable, as biochemical recurrence (BCR)...
November 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29662528/oncoplastic-surgery-for-the-conservative-treatment-of-breast-cancer-in-per%C3%A3%C2%BA-s-national-cancer-institute
#13
Gonzalo Javier Ziegler Rodriguez, Marcelo Diaz Chavez, Gabriela Guadalupe Calderon Valencia, Jose Manuel Cotrina Concha, Milko Raphael Garces Castre, Raul Mantilla
Background: Oncoplastic surgery for breast cancer (OPS) has been a surgical trend for the past 25 years. In 2012, OPS has been introduced as the standard treatment for a selected group of patients at the National Cancer Institute of Peru (INEN). The aim of this study is to describe our findings. Methods: This is a retrospective and descriptive study that identified demographics, tumour-pathologic features and includes patients solely treated since diagnosis until late follow-up at INEN...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29661810/metastases-in-prostate-cancer
#14
Federico La Manna, Sofia Karkampouna, Eugenio Zoni, Marta De Menna, Janine Hensel, George N Thalmann, Marianna Kruithof-de Julio
Prostate cancer (PCa) prognosis and clinical outcome is directly dependent on metastatic occurrence. The bone microenvironment is a favorable metastatic niche. Different biological processes have been suggested to contribute to the osteotropism of PCa such as hemodynamics, bone-specific signaling interactions, and the "seed and soil" hypothesis. However, prevalence of disseminating tumor cells in the bone is not proportional to the actual occurrence of metastases, as not all patients will develop bone metastases...
April 16, 2018: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/29661588/impact-of-metabolic-diseases-drugs-and-dietary-factors-on-prostate-cancer-risk-recurrence-and-survival-a-systematic-review-by-the-european-association-of-urology-section-of-oncological-urology
#15
REVIEW
Riccardo Campi, Sabine D Brookman-May, Jose Daniel Subiela Henríquez, Bülent Akdoğan, Maurizio Brausi, Tobias Klatte, Johan F Langenhuijsen, Estefania Linares-Espinos, Martin Marszalek, Morgan Roupret, Christian G Stief, Alessandro Volpe, Andrea Minervini, Oscar Rodriguez-Faba
CONTEXT: To date, established risk factors for prostate cancer (PCa) are limited to age, race, family history, and certain genetic polymorphisms. Despite great research efforts, available evidence on potentially modifiable risk factors is conflicting. Moreover, most studies on PCa risk factors did not consider the impact of prostate-specific antigen (PSA) testing on PCa diagnosis. OBJECTIVE: To provide a detailed overview of the latest evidence on the role of metabolic diseases, drugs, and dietary factors for risk of PCa incidence, recurrence, and survival in men exposed to PSA testing...
April 13, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29661495/narcotics-reduction-quality-and-safety-in-gynecologic-oncology-surgery-in-the-first-year-of-enhanced-recovery-after-surgery-protocol-implementation
#16
Jennifer E Bergstrom, Marla E Scott, Yewande Alimi, Ting-Tai Yen, Deborah Hobson, Karime K Machado, Edward J Tanner, Amanda N Fader, Sarah M Temkin, Stephanie Wethington, Kimberly Levinson, Sam Sokolinsky, Brandyn Lau, Rebecca L Stone
OBJECTIVES: Enhanced Recovery After Surgery (ERAS) programs are mechanisms for achieving value-based improvements in surgery. This report provides a detailed analysis of the impact of an ERAS program on patient outcomes as well as quality and safety measures during implementation on a gynecologic oncology service at a major academic medical center. METHODS: A retrospective review of gynecologic oncology patients undergoing elective laparotomy during the implementation phase of an ERAS program (January 2016 through December 2016) was performed...
April 13, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29661282/impact-of-fresh-frozen-plasma-transfusion-on-postoperative-inflammation-and-prognosis-of-colorectal-liver-metastases
#17
Yuichi Nakaseko, Koichiro Haruki, Hiroaki Shiba, Takashi Horiuchi, Nobuhiro Saito, Taro Sakamoto, Takeshi Gocho, Katsuhiko Yanaga
BACKGROUND: Blood transfusion has been reported to be associated with immunomodulation and poor oncologic outcomes in several malignancies. The aim of the study is to investigate the influence of the use of fresh frozen plasma (FFP) on long-term outcomes in patients with colorectal liver metastases (CRLM) after hepatic resection. MATERIALS AND METHODS: The study comprised 127 patients who had undergone first hepatic resection for CRLM between April 2000 and December 2013...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29661280/prognostic-value-of-neoadjuvant-treatment-response-in-locally-advanced-rectal-cancer
#18
Yvonne H Sada, Hop S Tran Cao, George J Chang, Avo Artinyan, Benjamin L Musher, Brandon G Smaglo, Nader N Massarweh
BACKGROUND: For locally advanced rectal cancer, response to neoadjuvant radiation has been associated with improved outcomes but has not been well characterized in general practice. The goals of this study were to describe disease response rates after neoadjuvant treatment and to evaluate the association between disease response and survival. MATERIALS AND METHODS: Retrospective cohort study of patients aged 18-80 y with clinical stage II and III rectal adenocarcinoma in the National Cancer Database (2006-2012)...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29660595/computer-assisted-subtyping-and-prognosis-for-non-small-cell-lung-cancer-patients-with-unresectable-tumor
#19
Maliazurina Saad, Tae-Sun Choi
BACKGROUND: The histological classification or subtyping of non-small cell lung cancer is essential for systematic therapy decisions. Differentiating between the two main subtypes of pulmonary adenocarcinoma and squamous cell carcinoma highlights the considerable differences that exist in the prognosis of patient outcomes. Physicians rely on a pathological analysis to reveal these phenotypic variations that requires invasive methods, such as biopsy and resection sample, but almost 70% of tumors are unresectable at the point of diagnosis...
April 4, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29659447/the-cost-of-contralateral-prophylactic-mastectomy-in-women-with-unilateral-breast-cancer
#20
Jessica I Billig, Anthony Duncan, Lin Zhong, Oluseyi Aliu, Erika D Sears, Kevin C Chung, Adeyiza O Momoh
BACKGROUND: Contralateral prophylactic mastectomy (CPM) may be unnecessary from an oncologic perspective; therefore, the debate persists about the value of CPM in women with early stage unilateral breast cancer. Given finite healthcare resources, this study aims to evaluate the cost of contralateral prophylactic mastectomy and breast reconstruction. STUDY DESIGN: Women with unilateral breast cancer undergoing either unilateral mastectomy or unilateral mastectomy with CPM and immediate breast reconstruction (IBR) were selected from the Truven MarketScan databases between 2009 and 2013...
January 20, 2018: Plastic and Reconstructive Surgery
keyword
keyword
67040
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"