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https://www.readbyqxmd.com/read/28822426/-laryngopharyngeal-reflux-disease-and-laryngeal-precancerous-lesions
#1
Z W Li, S H Zhou
The laryngopharyngeal reflux disease (LPRD) is a general term for a series of symptoms and signs caused by reflux of the stomach contents to the upper part of the esophageal sphincter. In recent years, the laryngopharyngeal reflux (LPR) is getting more and more attention as laryngeal precancerous lesions and risk factors of laryngeal cancer. Laryngeal precancerous lesions plays a important role in the development of laryngeal cancer process. This article will review the role and mechanisms of LPR in the laryngeal precancerous lesions, and the status of anti-reflux in the treatment of laryngeal precancerous lesions...
August 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28822425/-understanding-of-laryngopharyngeal-reflux-is-in-confusion
#2
G Chen, W J Liao, X W Zhang
No abstract text is available yet for this article.
August 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28822052/bariatric-surgery-worldwide-baseline-demographic-description-and-one-year-outcomes-from-the-second-ifso-global-registry-report-2013-2015
#3
Richard Welbourn, Dimitri J Pournaras, John Dixon, Kelvin Higa, Robin Kinsman, Johan Ottosson, Almino Ramos, Bart van Wagensveld, Peter Walton, Rudolf Weiner, Natan Zundel
BACKGROUND: Five International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) surveys since 1998 have estimated the volume and type of bariatric surgery being done in constituent member countries. These reports did not include baseline demographic descriptions. METHODS: An IFSO Global Registry pilot project in 2014 demonstrated that it was possible to amalgamate large numbers of individual patient data from different local and national database systems...
August 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28821410/laparoscopic-redo-anti-reflux-surgery-case-series-of-different-presentations-varied-management-and-their-outcomes
#4
Hari Nageswaran, Ali Haque, Mohammed Zia, Ahmed Hassn
BACKGROUND: A minority of patients undergoing surgery for refractory gastroesophageal reflux disease (GORD) will require revision antireflux surgery ("redo-ARS") for persistent symptoms or complications. Although a repeat minimally invasive procedure for revision may be technically challenging due to post-operative changes, studies are beginning to show favourable data for the laparoscopic approach. METHOD: From a single institution 41 consecutive cases of laparoscopic redo-ARS performed by the same surgeon were classified by mode of presentation to analyse their intra-operative findings, management and post-operative outcomes...
August 15, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28820183/technique-of-retinal-gene-therapy-delivery-of-viral-vector-into-the-subretinal-space
#5
K Xue, M Groppe, A P Salvetti, R E MacLaren
PurposeSafe and reproducible delivery of gene therapy vector into the subretinal space is essential for successful targeting of the retinal pigment epithelium (RPE) and photoreceptors. The success of surgery is critical for the clinical efficacy of retinal gene therapy. Iatrogenic detachment of the degenerate (often adherent) retina in patients with hereditary retinal degenerations and small volume (eg, 0.1 ml) subretinal injections pose new surgical challenges.MethodsOur subretinal gene therapy technique involved pre-operative planning with optical coherence tomography (OCT) and autofluorescence (AF) imaging, 23 G pars plana vitrectomy, internal limiting membrane staining with Membrane Blue Dual (DORC BV, Zuidland, Netherlands), a two-step subretinal injection using a 41 G Teflon tipped cannula (DORC) first with normal saline to create a parafoveal bleb followed by slow infusion of viral vector via the same self-sealing retinotomy...
August 18, 2017: Eye
https://www.readbyqxmd.com/read/28818534/endoscopic-treatment-of-vesicoureteral-reflux-in-infants-can-we-do-it-and-should-we-do-it
#6
Sara Fuentes, Andrés Gómez-Fraile, Isabel Carrillo-Arroyo, Cristina Tordable-Ojeda, Daniel Cabezalí-Barbancho
Objective To evaluate the outcomes of endoscopic treatment of vesicoureteral reflux (VUR) performed on infants, and to discuss the possible role of this approach in selected cases. Material and Methods A retrospective analysis was conducted on the patients that underwent endoscopic injection of a bulking substance for VUR in our institution, and a comparison made with patients treated as infants and those treated later in life. Results A total 463 ureteric units were included (296 children), of which 47 of them were patients less than one year of age (infants, INF group), with the remaining 416 being included in a second group (children, CHL)...
August 14, 2017: Urology
https://www.readbyqxmd.com/read/28818211/evaluation-of-thrombolysis-using-tissue-plasminogen-activator-in-lower-extremity-deep-venous-thrombosis-with%C3%A2-concomitant-femoral-popliteal-venous-segment%C3%A2-involvement
#7
Mayin Lin, John C F Hsieh, Mian Hanif, Alan McDaniel, David K Chew
OBJECTIVE: Current guidelines recommend thrombolytic therapy for iliofemoral deep venous thrombosis (DVT). Anticoagulation is the standard treatment for femoral-popliteal and tibial-level DVT. The objective of this study was to evaluate the efficacy of catheter-directed thrombolysis (CDT) using tissue plasminogen activator vs standard anticoagulation alone in patients with lower extremity DVT involving the femoral-popliteal segment. METHODS: A retrospective review was performed of patients referred to the vascular surgery service with lower extremity DVT from 2006 to 2015...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28818054/comparison-of-the-trapezius-and-the-adductor-pollicis-muscle-as-predictor-of-good-intubating-conditions-a-randomized-controlled-trial
#8
Stefan Soltesz, Christian Stark, Karl G Noé, Michael Anapolski, Thomas Mencke
BACKGROUND: Adequate muscle relaxation is important for ensuring optimal conditions for intubation. Although acceleromyography of the adductor pollicis muscle is commonly used to assess conditions for intubation, we hypothesized that acceleromyography of the trapezius is more indicative of optimal intubating conditions. The primary outcome was the difference between both measurement sites with regard to prediction of good or acceptable intubating conditions. METHODS: Neuromuscular blockade after injection of rocuronium 0...
August 17, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28816003/prevalence-of-gastrointestinal-symptoms-in-angelman-syndrome
#9
Laura W Glassman, Olivia R Grocott, Portia A Kunz, Anna M Larson, Garret Zella, Kriston Ganguli, Ronald L Thibert
Angelman syndrome (AS) is a neurogenetic disorder characterized by intellectual disability, expressive speech impairment, movement disorder, epilepsy, and a happy demeanor. Children with AS are frequently reported to be poor feeders during infancy and as having gastrointestinal issues such as constipation, reflux, and abnormal food related behaviors throughout their lifetime. To assess the prevalence of gastrointestinal disorders in individuals with AS, we retrospectively analyzed medical records of 120 individuals seen at the Angelman Syndrome Clinic at Massachusetts General Hospital and 43 individuals seen at the University of North Carolina Comprehensive Angelman Clinic...
August 16, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28815866/catalytic-intramolecular-cycloaddition-reactions-using-a-discrete-molecular-architecture
#10
Partha Sarathi Mukherjee, Bijan Roy, Anthonisamy Devaraj, Rupak Saha, Suprita Jharimune, Ki-Whan Chi
A discrete tetragonal tube-shaped complex (MT-1) has been synthesized by coordination-driven self-assembly of a carbazole-based tetraimidazole donor L and a Pd(II) 90° acceptor, viz. [cis-(dppf)Pd(OTf)2] (dppf = diphenylphosphino ferrocene, OTf = CF3SO3-). Complex MT-1 was characterized by multinuclear NMR, ESI-MS and single crystal X-ray diffraction analysis (SCXRD), which showed its symmetrical tetrafacial tube-shaped architecture possessing a large cavity described by four aromatic walls. This coordination cage was successfully utilized as a molecular vessel to perform intramolecular cycloaddition reactions of O-allylated benzylidinebarbituric acid derivatives inside its confined nanospace...
August 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28815026/the-diagnostic-value-of-24-hour-ambulatory-intraesophageal-ph-impedance-in-patients-with-laryngopharyngeal-reflux-symptoms-comparable-with-typical-symptoms
#11
Yusuf S Sakin, Rukiye Vardar, Baha Sezgin, Zeynep Erdogan Cetin, Yasemin Alev, Esra Yildirim, Tayfun Kirazli, Serhat Bor
BACKGROUND: The diagnosis of laryngopharyngeal reflux is currently based on a combination of the patient history of multichannel intraluminal impedance and ambulatory pH (MII-pH); however, none of these findings alone is specific for the diagnosis of laryngopharyngeal reflux. We aimed to compare the baseline characteristics and esophageal baseline impedance values between patients with and without laryngopharyngeal reflux symptoms. METHODS: We retrospectively analyzed data from two groups of patients with laryngopharyngeal reflux according to their reflux finding score (RFS) as scored by ENTs...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28814707/-transurethral-injection-using-deflux-for-vesicoureteral-reflux-in-three-adult-women-with-frequent-febrile-urinary-tract-infections
#12
Yoko Saito, Jun-Ichi Teranishi, Yohei Kumano, Masahiro Yasui, Syohei Mori, Shuko Yoneyama, Ayako Gobara, Takashi Kawahara, Hiroji Uemura
We report three patients with frequent febrile urinary tract infections (fUTI) who underwent transurethral injection therapy with Deflux for vesicoureteral reflux (VUR). The first case was in a 52-yearold woman who was initially diagnosed with right grade II and left grade I VUR at 18 years of age. She frequently experienced fUTI due to VUR. The second case was in a 29-year-old woman. At age 23,she was diagnosed with right grade III VUR when she developed fUTI. After that,she repeatedly developed fUTI. The third case was in a 40-year-old woman who had frequently experienced fUTI since 25 years of age and had gradually become antibiotics-resistant...
July 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28812459/alox15-immunohistochemistry-aids-in-the-diagnosis-of-eosinophilic-esophagitis-on-pauci-eosinophilic-biopsies-in-children
#13
Yiang Hui, Sonja Chen, Kara A Lombardo, Murray B Resnick, Shamlal Mangray, Andres Matoso
Histologically, esophageal biopsies should have ≥15 intraepithelial eosinophils (IEEs) per high power field (HPF) to support a clinicopathologic diagnosis of eosinophilic esophagitis (EoE). Children with clinically apparent EoE may show pauci-eosinophilic biopsies due to patchy involvement. Immunostaining (Immunohistochemistry) for arachidonate-15 lipooxygenase (ALOX15) has been demonstrated to be a sensitive marker for EoE. We retrospectively assessed the expression of ALOX15 in 48 biopsies from 21 patients with established diagnosis of EoE and with tissue fragments below the threshold of 15 IEEs/HPF...
September 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28811943/reviewing-the-emergence-of-lactococcus-garvieae-a-case-of-catheter-associated-urinary-tract-infection-caused-by-lactococcus-garvieae-and-escherichia-coli-coinfection
#14
Tatvam T Choksi, Farhan Dadani
Lactococcus garvieae is considered a low virulence organism which is rarely associated with human infections. Most of the reported cases have been associated with bacteremia with or without endocarditis. We report a rare case of catheter associated urinary tract infection (CAUTI) caused by Lactococcus garvieae and Escherichia coli coinfection without any bacteremia in a patient with indwelling urinary catheter placed for benign prostatic hyperplasia (BPH). The patient also had a history of gastroesophageal reflux disease (GERD) with long standing famotidine treatment...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28811716/development-and-validation-of-a-simple-and-multifaceted-instrument-gerd-test-for-the-clinical-evaluation-of-gastroesophageal-reflux-and-dyspeptic-symptoms
#15
Koji Nakada, Nobuyuki Matsuhashi, Katsuhiko Iwakiri, Atsushi Oshio, Takashi Joh, Kazuhide Higuchi, Ken Haruma
AIM: To evaluate the psychometric properties of a newly developed questionnaire, known as the gastroesophageal reflux and dyspepsia therapeutic efficacy and satisfaction test (GERD-TEST), in patients with GERD. METHODS: Japanese patients with predominant GERD symptoms recruited according to the Montreal definition were treated for 4 wk using a standard dose of proton pump inhibitor (PPI). The GERD-TEST and the Medical Outcome Study Short Form-8 Health Survey (SF-8) were administered at baseline and after 4 wk of treatment...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28811703/barrett-s-oesophagus-current-controversies
#16
REVIEW
Chidi Amadi, Piers Gatenby
Oesophageal adenocarcinoma is rapidly increasing in Western countries. This tumour frequently presents late in its course with metastatic disease and has a very poor prognosis. Barrett's oesophagus is an acquired condition whereby the native squamous mucosa of the lower oesophagus is replaced by columnar epithelium following prolonged gastro-oesophageal reflux and is the recognised precursor lesion for oesophageal adenocarcinoma. There are multiple national and society guidelines regarding screening, surveillance and management of Barrett's oesophagus, however all are limited regarding a clear evidence base for a well-demonstrated benefit and cost-effectiveness of surveillance, and robust risk stratification for patients to best use resources...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28811016/activated-biochar-preparation-characterization-and-electroanalytical-application-in-an-alternative-strategy-of-nickel-determination
#17
Cristiane Kalinke, Paulo Roberto Oliveira, Geovane Arruda Oliveira, Antonio Sálvio Mangrich, Luiz H Marcolino-Junior, Márcio F Bergamini
This work reports for the first time the use of chemically activated biochar as electrode modifier for nickel determination. The biochar activation was performed by refluxing with HNO3, which promoted a higher nickel preconcentration compared to unmodified and modified biochar precursor electrodes. Morphological and structural characterization revealed the increase of surface acid groups, surface area and porosity of biochar after activation. Nickel determination was investigated adopting an alternative voltammetric methodology based on monitoring the Ni(II)/Ni(III) redox couple...
August 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28809722/classification-for-assessing-the-quality-of-diagnostic-coronary-angiography
#18
Philippe Généreux, Roxana Mehran, Martin B Leon, Nicolas Bettinger, Gregg W Stone
Coronary angiography remains the gold standard for diagnosing obstructive coronary artery disease. However, no standardized, objective, and quantitative classification to assess the quality of coronary angiography exists. In the present report, we sought to establish a novel standardized quantitative classification for the quality of coronary angiography, taking into consideration two main parameters: coronary contrast filling and coronary sinus contrast reflux. Intraobserver and interobserver reproducibility performed among 70 angiograms and 9 readers demonstrated excellent and substantial reproducibility, respectively...
August 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28808884/outcomes-of-laparoscopic-hiatal-hernia-repair-in-nine-bariatric-patients-with-prior-sleeve-gastrectomy
#19
Francisco Igor B Macedo, Mia Mowzoon, Vijay K Mittal, Mubashir Sabir
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) may exacerbate gastroesophageal reflux disease (GERD) in patients with a hiatal hernia (HH). Surgical repair may be needed, however prior LSG precludes standard HH repair with fundoplication. METHODS: We retrospectively reviewed our experience with bariatric patients with prior LSG undergoing laparoscopic HH repair from August 2010 to July 2016. Patient demographics and outcomes including mortality, length of stay (LOS), readmission rates, reoperation, and complications were described...
August 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28808763/characteristics-of-gastroesophageal-reflux-in-pediatric-patients-with-neurological-impairment
#20
Hisayoshi Kawahara, Yuko Tazuke, Hideki Soh, Noriaki Usui, Hiroomi Okuyama
PURPOSE: To clarify the characteristics of gastroesophageal reflux (GER) in pediatric patients with neurological impairment (NI). METHODS: Twenty-six patients with NI, 1-17-year-old, fed via a nasogastric tube were categorized based on the absence (group I) or presence (group II) of abnormal GER, defined with multichannel intraluminal impedance-pH monitoring as %time with an esophageal pH <4.0 being ≥5.0% or number of liquid/mixed bolus reflux events(RE) >70 in 24 h...
August 14, 2017: Pediatric Surgery International
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