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Pec block

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https://www.readbyqxmd.com/read/28932733/pectoral-nerve-block-pecs-block-with-sedation-for-breast-conserving-surgery-without-general-anesthesia
#1
Eun-Jin Moon, Seung-Beom Kim, Jun-Young Chung, Jeong-Yoon Song, Jae-Woo Yi
Most regional anesthesia in breast surgeries is performed as postoperative pain management under general anesthesia, and not as the primary anesthesia. Regional anesthesia has very few cardiovascular or pulmonary side-effects, as compared with general anesthesia. Pectoral nerve block is a relatively new technique, with fewer complications than other regional anesthesia. We performed Pecs I and Pec II block simultaneously as primary anesthesia under moderate sedation with dexmedetomidine for breast conserving surgery in a 49-year-old female patient with invasive ductal carcinoma...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28930678/dna-ligase-iv-guides-end-processing-choice-during-nonhomologous-end-joining
#2
Michael P Conlin, Dylan A Reid, George W Small, Howard H Chang, Go Watanabe, Michael R Lieber, Dale A Ramsden, Eli Rothenberg
Nonhomologous end joining (NHEJ) must adapt to diverse end structures during repair of chromosome breaks. Here, we investigate the mechanistic basis for this flexibility. DNA ends are aligned in a paired-end complex (PEC) by Ku, XLF, XRCC4, and DNA ligase IV (LIG4); we show by single-molecule analysis how terminal mispairs lead to mobilization of ends within PECs and consequent sampling of more end-alignment configurations. This remodeling is essential for direct ligation of damaged and mispaired ends during cellular NHEJ, since remodeling and ligation of such ends both require a LIG4-specific structural motif, insert1...
September 19, 2017: Cell Reports
https://www.readbyqxmd.com/read/28890559/comparison-of-the-post-operative-analgesic-effect-of-paravertebral-block-pectoral-nerve-block-and-local-infiltration-in-patients-undergoing-modified-radical-mastectomy-a-randomised-double-blind-trial
#3
Kartik Syal, Ankita Chandel
BACKGROUND AND AIMS: Paravertebral block, pectoral nerve (Pecs) block and wound infiltration are three modalities for post-operative analgesia following breast surgery. This study compares the analgesic efficacy of these techniques for post-operative analgesia. METHODS: Sixty-five patients with American Society of Anesthesiologists' physical status 1 or 2 undergoing modified radical mastectomy with axillary dissection were recruited for the study. All patients received 21 mL 0...
August 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28864252/design-of-protein-delivery-systems-by-mimicking-extracellular-mechanisms-for-protection-of-growth-factors
#4
Carla Silva, Agatha Carretero, Diana Soares da Costa, Rui L Reis, Ramon Novoa-Carballal, Iva Pashkuleva
Heparin sulfate proteoglycans (HSPGs) are responsible for the storage and stabilization of numerous growth factors in the extracellular matrix. In this complex native environment, the efficient binding of the growth factors is determined by multivalent, specific and reversible electrostatic interactions between the sulfate groups of HSPGs and the positively charged amino acids of the growth factor. Inspired by this naturally occurring stabilization process, we propose the use of diblock copolymers of heparin and polyethylene glycol (Hep-b-PEG) for protection and delivery of FGF-2...
August 30, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28654558/the-efficacy-of-ultrasound-guided-type-ii-pectoral-nerve-blocks-in-perioperative-pain-management-for-immediate-reconstruction-after-modified-radical-mastectomy-a-prospective-randomized-study
#5
Kaiyuan Wang, Xiaobei Zhang, Tingting Zhang, Hui Yue, Shan Sun, Hongwei Zhao, Peng Zhou
OBJECTIVES: The pectoral nerves (Pecs) II block is a technique that places local anesthetic between the thoracic muscles to block the axillary and breast regions. This study aimed to compare the quality of perioperative analgesia and side effects of the Pecs II block under general anesthesia versus general anesthesia alone in immediate unilateral breast reconstruction with an implant and latissimus dorsi (LD) flap after modified radical mastectomy. METHODS: Sixty-four patients scheduled for immediate breast reconstruction after modified radical mastectomy were randomly allocated into the Pecs II block under general anesthesia group (Group P, n=32) or the general anesthesia alone group (Group G, n=32)...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28625445/prospective-double-blind-randomized-placebo-controlled-clinical-trial-of-the-pectoral-nerves-pecs-block-type-ii
#6
Barbara Versyck, Geert-Jan van Geffen, Patrick Van Houwe
STUDY OBJECTIVE: The aim of this clinical trial was to test the hypothesis whether adding the pectoral nerves (Pecs) block type II to the anesthetic procedure reduces opioid consumption during and after breast surgery. DESIGN: A prospective randomized double blind placebo-controlled study. SETTING: A secondary hospital. PATIENTS: 140 breast cancer stage 1-3 patients undergoing mastectomy or tumorectomy with sentinel node or axillary node dissection...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28554710/the-pecs-ii-block-as-a-major-analgesic-component-for-clavicle-operations-a-description-of-7-case-reports
#7
J B Schuitemaker R, X Sala-Blanch, C L Rodriguez-Pérez, J T Mayoral R, L A López-Pantaleon, A P Sánchez-Cohen
Clavicle fractures correspond to 35% of traumatic fractures of the shoulder girdle. Regional anaesthesia has shown better analgesic results than systemic treatment for perioperative management. Innervation of the clavicle is complex, at present its knowledge raises controversy. The lateral pectoral nerve through the innervating musculature predominantly participates in the lateral and anterior part of the clavicle. The following report of 7 cases describes the effective postoperative analgesia of modified PEC II block in patients with middle third clavicle fracture or acromioclavicular dislocation who underwent a modified PEC II block for postoperative pain management, in the context of a multimodal analgesia...
May 26, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28412658/cds-mn-quantum-dot-functionalized-g-c3n4-nanohybrids-as-signal-generation-tags-for-photoelectrochemical-immunoassay-of-prostate-specific-antigen-coupling-dnazyme-concatamer-with-enzymatic-biocatalytic-precipitation
#8
Kangyao Zhang, Shuzhen Lv, Zhenzhen Lin, Dianping Tang
A new photoelectrochemical (PEC) immunosensor based on Mn-doped CdS quantum dots (CdS:Mn QDs) on g-C3N4 nanosheets was developed for the sensitive detection of prostate specific antibody (PSA) in biological fluids. The signal derived from the as-synthesized Cd:Mn QDs-functionalized g-C3N4 nanohybrids via a hydrothermal method and was amplified through DNAzyme concatamers on gold nanoparticles accompanying enzymatic biocatalytic precipitation. Experimental results by UV-vis absorption spectra and photoluminescence revealed that CdS:Mn QDs/g-C3N4 nanohybrids exhibited higher photocurrent than those of CdS:Mn QDs and g-C3N4 alone...
September 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28401236/an-unconventional-outer-to-inner-synthesis-strategy-for-core-au-shell-nanostructures-with-photo-electrochemical-enhancement
#9
Zhuo Zhang, Minki Baek, Hongseon Song, Kijung Yong
In this work, an outer-to-inner strategy is demonstrated to simultaneously fabricate core-shell NPs and assemble them onto a scaffold. Specifically, the shell material is deposited onto the scaffold first, and then a layer of the core material (Au) is covered on the shell surface. Finally, the core (Au)-shell nanoparticles (NPs) are formed on the scaffold after annealing. As examples, Au-Bi2S3, Au-CdS and Au-CdSe core-shell NPs are grown on the surface of ZnO nanorods (NRs) via this strategy and exhibit enhanced photoelectrochemical (PEC) efficiency...
April 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28367293/thoracic-interfascial-nerve-block-for-breast-surgery-in-a-pregnant-woman-a-case-report
#10
Boohwi Hong, Seok-Hwa Yoon, Ann Misun Youn, Bum June Kim, Seunghyun Song, Yeomyung Yoon
Regional anesthesia for non-obstetric surgery in parturients is a method to decrease patient and fetal risk during general anesthesia. Thoracic interfascial nerve block can be used as an analgesic technique for surgical procedures of the thorax. The Pecs II block is an interfascial block that targets not only the medial and lateral pectoral nerves, but also the lateral cutaneous branch of the intercostal nerve. Pecto-intercostal fascial block (PIFB) targets the anterior cutaneous branch of the intercostal nerve...
April 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28213214/bifunctional-polydopamine-thin-film-coated-zinc-oxide-nanorods-for-label-free-photoelectrochemical-immunoassay
#11
Yan Yang, Weihua Hu
Photoelectrochemical (PEC) detection is a promising method for label-free immunoassay by reporting the specific biological recognition events with electrical signals. However, it is challenging to rationally incorporate immunosensing components with a photocurrent conversion interface, which generally necessitates multistep fabrication and careful tailoring of various components such as photoactive material and biological probe. For high detection reliability and reproducibility, it is highly desirable to rationally construct an efficient PEC interface with architecture as simple as possible...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28184271/surgical-excision-of-the-breast-giant-fibroadenoma-under-regional-anesthesia-by-pecs-ii-and-internal-intercostal-plane-block-a-case-report-and-brief-technical-description-a-case-report
#12
Hyungtae Kim, Junho Shim, Ikthae Kim
A 22-years-old female patient at 171 cm and 67 kg visited the Department of Breast Surgery of the hospital with a mass accompanied with pain on the left side breast as chief complaints. Since physical examination revealed a suspected huge mass, breast surgeon decided to perform surgical excision and requested anesthesia to our department. Surgery of breast tumor is often under local anesthesia. However, in case of big size tumor, surgery is usually performed under general anesthesia. The patient feared general anesthesia...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28137363/assessment-of-the-genotoxicity-of-the-tyrosine-kinase-inhibitor-imatinib-mesylate-in-cultured-fish-and-human-cells
#13
Matjaž Novak, Bojana Žegura, Jana Nunić, Goran Gajski, Marko Gerić, Vera Garaj-Vrhovac, Metka Filipič
The selective tyrosine kinase inhibitor imatinib mesylate (IM) is a widely used anticancer drug. Recent studies showing that IM can induce DNA and chromosomal damage in crustaceans and higher plants prompted us to re-examine its potential genotoxicity. IM was not mutagenic in the Ames assay (Salmonella typhimurium). Cytotoxicity and genotoxicity were evaluated in vitro in zebrafish (Danio rerio) liver (ZFL), human hepatoma (HepG2), and human peripheral blood lymphocyte (HPBL) cells. Genotoxicity was determined with the comet assay and with the cytokinesis-block micronucleus cytome assay...
February 2017: Mutation Research
https://www.readbyqxmd.com/read/28064502/one-pot-synthesis-of-amino-acid-based-polyelectrolytes-and-nanoparticle-synthesis
#14
Stefan Mommer, Helmut Keul, Martin Möller
In this manuscript, a biscyclic monomer with an epoxide and a thiolactone ring connected by a urethane bond is used for the synthesis of amino acid-functional polyelectrolytes. In a first step, lithium salts of amino acids react selectively with the thiolactone ring by ring-opening, formation of an amide bond, and a thiol group. In a second step and in the presence of a base a polymeric building block is formed by polyaddition of the thiolate to the epoxide ring. The reaction occurs at room temperature in water as solvent...
January 9, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/27988479/label-free-and-high-throughput-biosensing-of-multiple-tumor-markers-on-a-single-light-addressable-photoelectrochemical-sensor
#15
Juan Wang, Juan Long, Zhihong Liu, Wangze Wu, Chengguo Hu
The sensitive and label-free detection of multiple biomarkers on a single electrode by photoelectrochemical (PEC) sensors based on light addressing strategies is very attractive for developing portable and high-throughput biosensing systems. The essential prerequisite of this proposal is the employment of uniform photovoltaic material modified electrodes with high conversion efficiency. Herein, a novel two-step constant potential deposition method for the rapid fabrication of bismuth sulfide film modified ITO electrodes (Bi2S3/ITO) was established...
May 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27871558/combipecs-the-single-injection-technique-of-pectoral-nerve-blocks-1-and-2-a-case-series
#16
Arunangshu Chakraborty, Rakhi Khemka, Taniya Datta, Suparna Mitra
Ultrasound-guided Pecs block can provide perioperative analgesia for breast surgery. A single-injection technique (COMBIPECS) combines both Pecs 1 and Pecs 2 blocks in a single needle pass. This technique saves time and is equally effective as the modified Pecs block which uses 2 needle passes. We present a case series of 21 patients who received the COMBIPECS block as a part of multimodal analgesia for breast cancer surgery. The block was administered before the surgery after induction of general anesthesia...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27863288/broad-ion-beam-serial-section-tomography
#17
B Winiarski, A Gholinia, K Mingard, M Gee, G E Thompson, P J Withers
Here we examine the potential of serial Broad Ion Beam (BIB) Ar(+) ion polishing as an advanced serial section tomography (SST) technique for destructive 3D material characterisation for collecting data from volumes with lateral dimensions significantly greater than 100µm and potentially over millimetre sized areas. Further, the associated low level of damage introduced makes BIB milling very well suited to 3D EBSD acquisition with very high indexing rates. Block face serial sectioning data registration schemes usually assume that the data comprises a series of parallel, planar slices...
January 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/27851263/1628-pecs-i-ii-blocks-as-rescue-analgesia-in-a-patient-undergoing-port-access-cardiac-surgery
#18
Suraj Yalamuri, Rebecca Klinger, William Bullock, Donald Glower, Jeffrey Gadsden, Brandi Bottiger
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27829018/paravertebral-block-plus-thoracic-wall-block-versus-paravertebral-block-alone-for-analgesia-of-modified-radical-mastectomy-a-retrospective-cohort-study
#19
COMPARATIVE STUDY
Nai-Liang Li, Ben-Long Yu, Chen-Fang Hung
BACKGROUND AND OBJECTIVES: Paravertebral block placement was the main anesthetic technique for modified radical mastectomy in our hospital until February 2014, when its combination with blocks targeting the pectoral musculature was initiated. We compared the analgesic effects of paravertebral blocks with or without blocks targeting the pectoral musculature for modified radical mastectomy. METHODS: We retrospectively collected data from a single surgeon and anesthesiologist from June 1, 2012, to May 31, 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27817875/photoelectrochemical-cell-for-simultaneous-electricity-generation-and-heavy-metals-recovery-from-wastewater
#20
Dawei Wang, Yi Li, Gianluca Li Puma, Panagiotis Lianos, Chao Wang, Peifang Wang
The feasibility of simultaneous recovery of heavy metals from wastewater (e.g., acid mining and electroplating) and production of electricity is demonstrated in a novel photoelectrochemical cell (PEC). The photoanode of the cell bears a nanoparticulate titania (TiO2) film capped with the block copolymer [poly(ethylene glycol)-b-poly(propylene glycol)-b-poly(ethylene glycol)] hole scavenger, which consumed photogenerated holes, while the photogenerated electrons transferred to a copper cathode reducing dissolved metal ions and produced electricity...
February 5, 2017: Journal of Hazardous Materials
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