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https://www.readbyqxmd.com/read/28929035/porcine-urinary-bladder-matrix-for-management-of-infected-radiation-mastectomy-wound
#1
Yana Puckett, Theophilus Pham, Shirley McReynolds, Catherine A Ronaghan
We present a case report on the successful healing of a Pseudomonas infection wound in a 52-year-old female with morbid obesity, noninsulin dependent diabetes mellitus and a history of tobacco use, who presented with Stage IIIA (T3, N2, Mo) infiltrating ductal carcinoma. The patient received neoadjuvant chemotherapy prior to her bilateral skin-sparing total mastectomies with right axillary sentinel lymphadenectomy. She also had staged reconstruction with temporary breast implants and plans for deep inferior epigastric perforator flaps...
July 10, 2017: Curēus
https://www.readbyqxmd.com/read/28916957/perspectives-of-women-considering-bilateral-prophylactic-mastectomy-and-their-peers-towards-a-telephone-based-peer-support-intervention
#2
D St-Pierre, K Bouchard, L Gauthier, J Chiquette, Michel Dorval
Prophylactic mastectomy is an effective strategy to reduce the risk of breast cancer for women carrying a BRCA1/2 germline mutation. This decision is complex and may raise various concerns. Women considering this surgery have reported their desire to discuss the implications of this procedure with women who have undergone prophylactic mastectomy. We conducted a qualitative study to describe the topics covered during a telephone-based peer support intervention between women considering prophylactic mastectomy (recipients) and women who had undergone this surgery (peers), and to explore their perspectives regarding the intervention...
September 15, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28890559/comparison-of-the-post-operative-analgesic-effect-of-paravertebral-block-pectoral-nerve-block-and-local-infiltration-in-patients-undergoing-modified-radical-mastectomy-a-randomised-double-blind-trial
#3
Kartik Syal, Ankita Chandel
BACKGROUND AND AIMS: Paravertebral block, pectoral nerve (Pecs) block and wound infiltration are three modalities for post-operative analgesia following breast surgery. This study compares the analgesic efficacy of these techniques for post-operative analgesia. METHODS: Sixty-five patients with American Society of Anesthesiologists' physical status 1 or 2 undergoing modified radical mastectomy with axillary dissection were recruited for the study. All patients received 21 mL 0...
August 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28870961/the-local-recurrence-of-breast-cancer-with-squamous-metaplasia-and-obvious-histological-heterogeneity
#4
Nami Yamashita, Eriko Tokunaga, Hidetaka Yamamoto, Chikako Shimizu, Kenji Taketani, Yuka Inoue, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
CASE REPORT: We herein report a case of local recurrence of breast cancer with squamous metaplasia and obvious intratumoral and intertumoral heterogeneity. A 39-year-old female patient was diagnosed with T3N2M0 stage IIIB right breast cancer and underwent right total mastectomy and axillar lymph node dissection. At four years after surgery, she became aware of chest wall pain and diagnostic imaging revealed recurrence in the lung, right thoracic wall and sternum. The recurrent lesions remained stable for 18 months with endocrine therapy...
September 2017: Anticancer Research
https://www.readbyqxmd.com/read/28862111/how-can-we-improve-education-of-breast-surgeons-across-europe
#5
Agnieszka Kolacinska
The proposed global curriculum developed by the American Society of Surgical Oncology (SSO) and the European Society of Surgical Oncology (ESSO) and the textbook: provides a state-of- the- art of breast cancer surgery, complements the syllabus and curriculum of the Union Europeenne des Medecins Specialistes (UEMS) examination in breast surgery/ European Board of Surgery Qualification in Breast Surgery (EBSQinBS) administered by ESSO (1) Knowledge and understanding of the principles of breast cancer incidence, aetiology, risk factors, genetics, premalignant and high-risk lesions, pathology, prognostic and predictive factors, risk prediction models, screening, diagnosis and imaging, breast cancer, oncoplastic, reconstructive breast surgery, axillary surgery and future perspective for this, radiation therapy, neoadjuvant and adjuvant systemic treatment- endocrine-, immuno- and chemotherapy, side effects and toxicities of treatment, locoregional recurrence, follow-up, locally advanced breast cancer, metastatic breast cancer, breast cancer in young and elderly patients, survivor issues, lymphedema, palliative care, chroni pain, body image and sexuality, fertility issues, cognitive functions, etc...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28861642/chronic-pain-and-other-symptoms-among-breast-cancer-survivors-prevalence-predictors-and-effects-on-quality-of-life
#6
Rola Hamood, Hatem Hamood, Ilya Merhasin, Lital Keinan-Boker
PURPOSE: To investigate prevalence and risk factors associated with self-reported chronic pain, and other symptoms related to breast cancer or its treatment among breast cancer survivors (BCS). METHODS: A cross-sectional study of a random sample of 410 female BCS, members of "Leumit" healthcare fund, diagnosed with primary nonmetastatic invasive breast cancer in the years 2002-2012. The study questionnaire included questions on health-related quality of life, pain symptoms, and was completed by all women contacted...
August 31, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28860708/onychomadesis-associated-with-chemotherapy-case-report-and-mini-literature-review
#7
Ang Li, Yanqiong Li, Lingzhi Ge, Ping Li, Wenfei Li
The side effects of chemotherapy drugs have increased in recent years, and some side effects can lead to onychomadesis. A 72-year-old woman who was diagnosed with an invasive ductal carcinoma of the right breast underwent a modified radical mastectomy in April 2015, followed by chemotherapy with capecitabine and nanoparticle albumin-bound paclitaxel (nab-paclitaxel). Subsequently, the patient experienced palmoplantar redness, pain, onycholysis, a transparent serous exudate, and onychomadesis. The chemotherapy was discontinued, and the patient was treated with oral vitamin B6, a polymyxin ointment, and a high-energy red light...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28844204/ocular-metastasis-from-breast-carcinoma-simulating-anterior-scleritis-a-case-report
#8
Ritesh Kumar Shah, Samir Lamichhane
BACKGROUND: Breast cancer is one of the commonest sources of ocular metastasis. Patients with ocular metastatic disease can present with a variable clinical picture. Patients with a history of breast cancer presenting with any eye symptom should be evaluated with consideration of ocular metastasis. CASE PRESENTATION: We report a case of ocular metastasis in a 46-year-old Brahmin woman presenting with right eye pain. She had been treated for stage IIIc left-sided breast cancer 2 years ago with six cycles of chemotherapy with docetaxel, adriamycin, and cyclophosphamide after undergoing modified radical mastectomy...
August 28, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28831358/patient-reported-outcomes-are-better-after-oncoplastic-breast-conservation-than-after-mastectomy-and-autologous-reconstruction
#9
Natalie D Chand, Victoria Browne, Nirmala Paramanathan, Lashan J Peiris, Siobhan A Laws, Richard M Rainsbury
Oncoplastic breast-conserving surgery (OBCS) avoids mastectomy for larger tumors, but patient-reported outcomes are unknown. METHODS: The BREAST-Q questionnaire was distributed to 333 women following therapeutic mammaplasty or latissimus dorsi (LD) miniflap since 1991 [tumor diameter, 32.5 (5-100) mm). QScore software generated scores/100 for breast appearance, physical, emotional, and sexual wellbeing. Outcomes following therapeutic mammaplasty and LD miniflap were compared and qualitative data analyzed to identify common themes relating to satisfaction...
July 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28820520/response-to-assessing-the-impact-of-acupuncture-on-pain-nausea-anxiety-and-coping-in-women-undergoing-a-mastectomy
#10
Jose M Moran, Antonio S Fernández, Juan D Pedrera-Zamorano
We read with interest the pilot randomized, controlled trial by Quinlan-Woodward et al. (2016) published in Oncology Nursing Forum about the impact of acupuncture on pain, nausea, anxiety, and coping in women undergoing a mastectomy. We think that there are both theoretical and methodologic issues that do not allow the authors to conclude that their study demonstrated that acupuncture delivered postoperatively in the hospital after mastectomy can reduce the severity of symptoms experienced and increase the patient's ability to cope with her symptoms...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28816143/radiation-therapy-versus-no-radiation-therapy-to-the-neo-breast-following-skin-sparing-mastectomy-and-immediate-autologous-free-flap-reconstruction-for-breast-cancer-patient-reported-and-surgical-outcomes-at-1-year-a-mastectomy-reconstruction-outcomes-consortium
#11
MULTICENTER STUDY
Andrew L Cooke, Julian Diaz-Abele, Tom Hayakawa, Ed Buchel, Kimberly Dalke, Pascal Lambert
PURPOSE: To determine whether adjuvant radiation therapy (RT) is associated with adverse patient-reported outcomes and surgical complications 1 year after skin-sparing mastectomy and immediate autologous free flap reconstruction for breast cancer. METHODS AND MATERIALS: We compared 24 domains of patient-reported outcome measures 1 year after autologous reconstruction between patients who received adjuvant RT and those who did not. A total of 125 patients who underwent surgery between 2012 and 2015 at our institution were included from the Mastectomy Reconstruction Outcomes Consortium study database...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28806288/acellular-dermal-matrix-in-immediate-expander-implant-breast-reconstruction-a-multicenter-assessment-of-risks-and-benefits
#12
Michael Sorkin, Ji Qi, Hyungjin M Kim, Jennifer B Hamill, Jeffrey H Kozlow, Andrea L Pusic, Edwin G Wilkins
INTRODUCTION: Acellular dermal matrix (ADM) has gained widespread acceptance in immediate expander/implant reconstruction due to perceived benefits, including improved expansion dynamics and superior aesthetic results. Although previous investigators have evaluated its risks, few studies have assessed the impact of ADM on other outcomes, including patient-reported measures. METHODS: The Mastectomy Reconstruction Outcomes Consortium (MROC) Study used a prospective cohort design to evaluate patients undergoing post-mastectomy reconstruction from 10 centers and 58 participating surgeons between 2012 and 2015...
August 3, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28797856/neuropathic-pain-after-breast-cancer-treatment-characterization-and-risk-factors
#13
Susana Pereira, Filipa Fontes, Teresa Sonin, Teresa Dias, Maria Fragoso, José Castro-Lopes, Nuno Lunet
CONTEXT: Neuropathic pain (NP) may be an important contributor to the morbidity burden of breast cancer. OBJECTIVES: We aimed to quantify the incidence of NP in the first year after diagnosis of breast cancer, and to identify its main determinants. METHODS: We performed a prospective cohort study including 506 patients with incident breast cancer, recruited at the Portuguese Institute of Oncology of Porto, and followed for one year; patients with incident NP were additionally evaluated when this condition was diagnosed and after six months, to identify chronic NP...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28766233/prospective-study-comparing-surgeons-pain-and-fatigue-associated-with-nipple-sparing-versus-skin-sparing-mastectomy
#14
Rubie Sue Jackson, Thomas Sanders, Adrian Park, Robert Buras, Wen Liang, Christine Harris, Charles Mylander, Martin Rosman, Luther Holton, Devinder Singh, Laura Martino, Lorraine Tafra
BACKGROUND: Nipple-sparing mastectomy (NSM) is more technically challenging than skin-sparing mastectomy (SSM) but offers quality-of-life and cosmetic advantages. However, surgeon physical symptoms related to NSM workload have not been documented. METHODS: This was a prospective study using questionnaires to compare surgeon-reported physical symptoms before, during, and after NSM versus SSM. Surgeons also answered general questions about each mastectomy. Bilateral cases were performed simultaneously by two surgeons, who completed independent questionnaires...
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28759158/no-sting-barrier-film-to-protect-skin-in-adult-patients-findings-from-a-scoping-review-with-implications-for-evidence-based-practice
#15
Chiara Micheli, Alvisa Palese, Federica Canzan, Elisa Ambrosi
BACKGROUND: In the industrialized world, approximately 1-1.5% of the population has received treatments for skin lesions. In the 1990s, a polymeric barrier film called the No Sting Barrier Film (NSBF) was developed as an alternative to petrolatum-based ointments and zinc oxide formulas. To date, few studies have explored the effectiveness of NSBF in protecting skin integrity. AIMS: To map the methods, fields and outcomes used to produce evidence on NSBF effectiveness...
July 31, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28744155/efficacy-of-single-injection-unilateral-thoracic-paravertebral-block-for-post-open-cholecystectomy-pain-relief-a-prospective-randomized-study-at-gondar-university-hospital
#16
Demeke Yilkal Fentie, Endale Gebreegziabher Gebremedhn, Zewditu Abdissa Denu, Amare Hailekiros Gebreegzi
BACKGROUND: Cholecystectomy can be associated with considerable postoperative pain. While the benefits of paravertebral block (PVB) on pain after thoracotomy and mastectomy have been demonstrated, not enough investigations on the effects of PVB on pain after open cholecystectomy have been conducted. We tested the hypothesis that a single-injection thoracic PVB reduces pain scores, decreases opioid consumption, and prolongs analgesic request time after cholecystectomy. METHODS: Of 52 patients recruited, 50 completed the study...
2017: Local and Regional Anesthesia
https://www.readbyqxmd.com/read/28721091/comparison-of-single-injection-ultrasound-guided-approach-versus-multilevel-landmark-based-approach-for-thoracic-paravertebral-blockade-for-breast-tumor-resection-a-retrospective-analysis-at-a-tertiary-care-teaching-institution
#17
Jagroop Singh Saran, Amie L Hoefnagel, Kristin A Skinner, Changyong Feng, Daryl Irving Smith
BACKGROUND: The role of thoracic paravertebral blockade (TPVB) in decreasing opioid requirements in breast cancer surgery is well documented, and there is mounting evidence that this may improve survival and reduce the rate of malignancy recurrence following cancer-related mastectomy. We compared the two techniques currently in use at our institution, the anatomic landmark-guided (ALG) multilevel versus an ultrasound-guided (USG) single injection, to determine an optimal technique. METHODS: We retrospectively reviewed records of patients who received TPVB from January 2013 to December 2014...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28718036/paravertebral-blocks-reduce-narcotic-use-without-affecting-perfusion-in-patients-undergoing-autologous-breast-reconstruction
#18
Elizabeth B Odom, Nili Mehta, Rajiv P Parikh, Ryan Guffey, Terence M Myckatyn
BACKGROUND: Autologous breast reconstruction offers excellent long term outcomes after mastectomy. However, maintaining adequate postoperative analgesia remains challenging. Use of paravertebral blocks (PVBs) reduces postoperative narcotic use and length of stay, and enhanced recovery protocols with mixed analgesia methods are gaining popularity, but few studies have explored the intraoperative effects of these interventions. METHODS: Patients who underwent abdominally based autologous breast reconstruction between 2010 and 2016 were compiled into a retrospective database...
July 17, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28713853/factors-associated-with-acute-postoperative-pain-following-breast-reconstruction
#19
Anita R Kulkarni, Andrea L Pusic, Jennifer B Hamill, Hyungjin M Kim, Ji Qi, Edwin G Wilkins, Randy S Roth
INTRODUCTION: Post-mastectomy breast reconstruction has become an increasingly important component of breast cancer treatment. Unfortunately, some patients experience severe postoperative pain, placing them at risk for increased clinical morbidity and the development of disabling chronic pain. In an attempt to identify at-risk patients, we prospectively evaluated patient characteristics and medical/surgical variables associated with more severe acute post-reconstruction pain. METHODS: Women (N = 2207; one-week 82...
March 2017: JPRAS Open
https://www.readbyqxmd.com/read/28691269/the-effect-of-intraoperative-systemic-lidocaine-on-postoperative-persistent-pain-using-immpact-criteria-assessment-following-breast-cancer-surgery-a-randomized-double-blind-placebo-controlled-trial
#20
Mark C Kendall, Robert J McCarthy, Steve Panaro, Emily Goodwin, Jane M Bialek, Antoun Nader, Gildasio De Oliveira
OBJECTIVE: To compare the incidence in postsurgical persistent pain following breast cancer surgery in women receiving intravenous lidocaine compared to saline using validated pain instruments in accordance with the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) recommendations. METHODS: The study was a randomized, double-blinded, placebo-controlled, clinical trial. Subjects were randomized into Group 1 (1.5 mg/kg bolus of intravenous lidocaine followed by a 2mg/kg/hr infusion) or Group 2 (normal saline at the same bolus and infusion rate)...
July 10, 2017: Pain Practice: the Official Journal of World Institute of Pain
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