keyword
MENU ▼
Read by QxMD icon Read
search

Spinal cord computational model

keyword
https://www.readbyqxmd.com/read/28934801/increasing-rates-of-imaging-in-failed-back-surgery-syndrome-patients-implications-for-spinal-cord-stimulation
#1
S Harrison Farber, Jing L Han, Frank W Petraglia Iii, Robert Gramer, Siyun Yang, Promila Pagadala, Beth Parente, Jichun Xie, Jeffrey R Petrella, Shivanand P Lad
BACKGROUND: Failed back surgery syndrome (FBSS) has a high incidence following spinal surgery, is notoriously refractory to treatment, and results in high health care utilization. Spinal cord stimulation (SCS) is a well-accepted modality for pain relief in this population; however, until recently magnetic resonance imaging (MRI) was prohibited due to risk of heat conduction through the device. OBJECTIVES: We examined trends in imaging use over the past decade in patients with FBSS to determine its impact on health care utilization and implications for patients receiving SCS...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28923686/high-speed-video-analysis-improves-the-accuracy-of-spinal-cord-compression-measurement-in-a-mouse-contusion-model
#2
Marion Fournely, Yvan Petit, Éric Wagnac, Jérôme Laurin, Virginie Callot, Pierre-Jean Arnoux
BACKGROUND: Animal models of spinal cord injuries aim to utilize controlled and reproducible conditions. However, a literature review reveals that mouse contusion studies using equivalent protocols may show large disparities in the observed impact force vs. cord compression relationship. The overall purpose of this study was to investigate possible sources of bias in these measurements. The specific objective was to improve spinal cord compression measurements using a video-based setup to detect the impactor-spinal cord time-to-contact...
September 15, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28864351/adaptation-of-a-mr-imaging-protocol-into-a-real-time-clinical-biometric-ultrasound-protocol-for-persons-with-spinal-cord-injury-at-risk-for-deep-tissue-injury-a-reliability-study
#3
Jillian M Swaine, Andrew Moe, William Breidahl, Daniel L Bader, Cees W J Oomens, Leanne Lester, Edmond O'Loughlin, Nick Santamaria, Michael C Stacey
BACKGROUND: High strain in soft tissues that overly bony prominences are considered a risk factor for pressure ulcers (PUs) following spinal cord impairment (SCI) and have been computed using Finite Element methods (FEM). The aim of this study was to translate a MRI protocol into ultrasound (US) and determine between-operator reliability of expert sonographers measuring diameter of the inferior curvature of the ischial tuberosity (IT) and the thickness of the overlying soft tissue layers on able-bodied (AB) and SCI using real-time ultrasound...
August 1, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28854256/peripheral-denervation-participates-in-heterotopic-ossification-in-a-spinal-cord-injury-model
#4
Charlotte Debaud, Marjorie Salga, Laurent Begot, Xavier Holy, Malha Chedik, Nicolas de l'Escalopier, Fréderic Torossian, Jean-Pierre Levesque, Jean-Jacques Lataillade, Marie-Caroline Le Bousse-Kerdilès, François Genêt
We previously reported the development of a new acquired neurogenic HO (NHO) mouse model, combining spinal cord transection (SCI) and chemical muscle injury. Pathological mechanisms responsible for ectopic osteogenesis after central neurological damage are still to be elucidated. In this study, we first hypothesized that peripheral nervous system (PNS) might convey pathological signals from injured spinal cord to muscles in NHO mouse model. Secondly, we sought to determine whether SCI could lead to intramuscular modifications of BMP2 signaling pathways...
2017: PloS One
https://www.readbyqxmd.com/read/28834214/clinical-implementation-and-evaluation-of-the-acuros-dose-calculation-algorithm
#5
Chenyu Yan, Anthony G Combine, Greg Bednarz, Ronald J Lalonde, Bin Hu, Kathy Dickens, Raymond Wynn, Daniel C Pavord, M Saiful Huq
PURPOSE: The main aim of this study is to validate the Acuros XB dose calculation algorithm for a Varian Clinac iX linac in our clinics, and subsequently compare it with the wildely used AAA algorithm. METHODS AND MATERIALS: The source models for both Acuros XB and AAA were configured by importing the same measured beam data into Eclipse treatment planning system. Both algorithms were validated by comparing calculated dose with measured dose on a homogeneous water phantom for field sizes ranging from 6 cm × 6 cm to 40 cm × 40 cm...
August 20, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28814047/a-simple-tool-to-measure-spasticity-in-spinal-cord-injury-subjects
#6
Arash Arami, Nevio L Tagliamonte, Federica Tamburella, Hsieng-Yung Huang, Marco Molinari, Etienne Burdet
This work presents a wearable device and the algorithms for quantitative modelling of joint spasticity and its application in a pilot group of subjects with different levels of spinal cord injury. The device comprises light-weight instrumented handles to measure the interaction force between the subject and the physical therapist performing the tests, EMG sensors and inertial measurement units to measure muscle activity and joint kinematics. Experimental tests included the passive movement of different body segments, where the spasticity was expected, at different velocities...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28743454/convergence-of-primary-sensory-cortex-and-cerebellar-nuclei-pathways-in-the-whisker-system
#7
REVIEW
Carmen B Schäfer, Freek E Hoebeek
To safely maneuver through the environment the brain needs to compare active sensory information with ongoing motor programs. This process occurs at various levels in the brain: at the lower level, i.e., in the spinal cord, reflexes are generated for the most primitive motor responses; at the intermediate level, i.e., in the brainstem, various nuclei co-process sensory- and motor-related inputs; and, at the higher level cerebellum and thalamo-cortical networks individually compute suitable commands for fine-tuned motor output...
July 22, 2017: Neuroscience
https://www.readbyqxmd.com/read/28739474/traumatic-subaxial-cervical-facet-subluxation-and-dislocation-epidemiology-radiographic-analyses-and-risk-factors-for-spinal-cord-injury
#8
Ryan D Quarrington, Claire F Jones, Petar Tcherveniakov, Jillian M Clark, Simon J I Sandler, Yu Chao Lee, Shabnam Torabiardakani, John J Costi, Brian J C Freeman
BACKGROUND CONTEXT: Distractive-flexion injuries (DFIs) of the subaxial cervical spine are major contributors to spinal cord injury (SCI). Prompt assessment and early intervention of DFIs associated with SCI is crucial to optimize patient outcome; however, neurological examination of patients with subaxial cervical injury is often difficult, as patients commonly present with reduced levels of consciousness. Therefore, it is important to establish potential associations between injury epidemiology and radiographic features, and neurological involvement...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28730695/concurrent-electrical-cervicomedullary-stimulation-and-cervical-transcutaneous-spinal-direct-current-stimulation-result-in-a-stimulus-interaction
#9
Siobhan C Dongés, Siwei Bai, Janet L Taylor
What is the central question of this study? We previously showed that the motor pathway is not modified after cervical transcutaneous spinal direct current stimulation (tsDCS) applied using anterior-posterior electrodes. Here, we examine the motor pathway during stimulation. What is the main finding and its importance? We show that electrically elicited muscle responses to cervicomedullary stimulation are modified during tsDCS, whereas magnetically elicited responses are not. Modelling reveals electrical field modifications during concurrent tsDCS and electrical cervicomedullary stimulation...
July 20, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28720407/mechanical-properties-of-the-human-spinal-cord-under-the-compressive-loading
#10
Alireza Karimi, Ahmad Shojaei, Pedram Tehrani
The spinal cord as the most complex and critical part of the human body is responsible for the transmission of both motor and sensory impulses between the body and the brain. Due to its pivotal role any types of physical injury in that disrupts its function following by shortfalls, including the minor motor and sensory malfunctions as well as complicate quadriplegia and lifelong ventilator dependency. In order to shed light on the injuries to the spinal cord, the application of the computational models to simulate the trauma impact loading to that are deemed required...
July 15, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28715318/researching-fiber-networks-computational-modeling-of-complex-fibrous-tissue-geometries
#11
Sergey Makarov, Alvero Pascual Leone, Aapo Nummenmaa
Many types of human tissue-such as the brain and spinal cord of the central nervous system, the peripheral nervous system, and muscles, including the heart muscle-are fibrous in nature. Isotropic human models that assume homogeneous volumes for every individual tissue do not properly take this into account.
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28709751/does-muscle-atrophy-and-fatty-infiltration-plateau-or-persist-in-chronic-spinal-cord-injury
#12
Cameron D Moore, B Catharine Craven, Lehana Thabane, Alexandra Papaioannou, Jonathan D Adachi, Lora M Giangregorio
Atrophy and fatty infiltration of lower extremity muscle after spinal cord injury (SCI) predisposes individuals to metabolic syndrome and related diabetes and cardiovascular disease. The objective of this study was to prospectively measure changes in muscle atrophy and fat content of distal lower extremity muscles and explore related factors in a cohort of adults with chronic SCI and diverse impairments. Muscle cross-sectional area and density were calculated from peripheral quantitative computed tomography scans of the 66% site of the calf from 70 participants with chronic SCI (50 male, mean age 49 years, C2-T12, American Spinal Injury Association Impairment Scale A-D) at study enrollment and annually for 2 years...
July 11, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28660796/increased-stress-and-strain-on-the-spinal-cord-due-to-ossification-of-the-posterior-longitudinal-ligament-in-the-cervical-spine-under-flexion-after-laminectomy
#13
Batbayar Khuyagbaatar, Kyungsoo Kim, Won Man Park, SuKyoung Lee, Yoon Hyuk Kim
Myelopathy in the cervical spine due to cervical ossification of the posterior longitudinal ligament could be induced by static compression and/or dynamic factors. It has been suggested that dynamic factors need to be considered when planning and performing the decompression surgery on patients with the ossification of the posterior longitudinal ligament. A finite element model of the C2-C7 cervical spine in the neutral position was developed and used to generate flexion and extension of the cervical spine...
September 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28645572/longitudinal-associations-between-mental-health-conditions-and-overactive-bladder-in-women-veterans
#14
Catherine S Bradley, Ingrid E Nygaard, Stephen L Hillis, James C Torner, Anne G Sadler
BACKGROUND: One in 5 recently deployed US women veterans report overactive bladder symptoms. Mental health conditions such as depression and anxiety commonly co-occur in women with overactive bladder, but temporal relationships between these outcomes have not been well studied, and the mechanism behind this association is unknown. The Women Veterans Urinary Health Study, a nationwide longitudinal study in recently deployed women veterans, was designed to better understand relationships between overactive bladder and mental health conditions...
June 20, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28616040/stem-cell-transplantation-for-spinal-cord-injury-a-meta-analysis-of-treatment-effectiveness-and-safety
#15
Xiao Fan, Jin-Zhao Wang, Xiao-Min Lin, Li Zhang
OBJECTIVE: The aim of this study was to evaluate the effectiveness and safety of stem cell transplantation for spinal cord injury (SCI). DATA SOURCES: PubMed, EMBASE, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, Wanfang, and SinoMed databases were systematically searched by computer to select clinical randomized controlled trials using stem cell transplantation to treat SCI, published between each database initiation and July 2016...
May 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28586096/spinal-cord-multi-parametric-magnetic-resonance-imaging-for-survival-prediction-in-amyotrophic-lateral-sclerosis
#16
G Querin, M M El Mendili, T Lenglet, S Delphine, V Marchand-Pauvert, H Benali, P-F Pradat
BACKGROUND AND PURPOSE: Assessing survival is a critical issue in patients with amyotrophic lateral sclerosis (ALS). Neuroimaging seems to be promising in the assessment of disease severity and several studies also suggest a strong relationship between spinal cord (SC) atrophy described by magnetic resonance imaging (MRI) and disease progression. The aim of the study was to determine the predictive added value of multimodal SC MRI on survival. METHODS: Forty-nine ALS patients were recruited and clinical data were collected...
August 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28501711/protection-of-cortex-by-overlying-meninges-tissue-during-dynamic-indentation-of-the-adolescent-brain
#17
David B MacManus, Baptiste Pierrat, Jeremiah G Murphy, Michael D Gilchrist
Traumatic brain injury (TBI) has become a recent focus of biomedical research with a growing international effort targeting material characterization of brain tissue and simulations of trauma using computer models of the head and brain to try to elucidate the mechanisms and pathogenesis of TBI. The meninges, a collagenous protective tri-layer, which encloses the entire brain and spinal cord has been largely overlooked in these material characterization studies. This has resulted in a lack of accurate constitutive data for the cranial meninges, particularly under dynamic conditions such as those experienced during head impacts...
May 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28494130/visualization-of-stereoscopic-anatomic-models-of-the-paranasal-sinuses-and-cervical-vertebrae-from-the-surgical-and-procedural-perspective
#18
Jian Chen, Andrew D Smith, Majid A Khan, Allan R Sinning, Marianne L Conway, Dongmei Cui
Recent improvements in three-dimensional (3D) virtual modeling software allows anatomists to generate high-resolution, visually appealing, colored, anatomical 3D models from computed tomography (CT) images. In this study, high-resolution CT images of a cadaver were used to develop clinically relevant anatomic models including facial skull, nasal cavity, septum, turbinates, paranasal sinuses, optic nerve, pituitary gland, carotid artery, cervical vertebrae, atlanto-axial joint, cervical spinal cord, cervical nerve root, and vertebral artery that can be used to teach clinical trainees (students, residents, and fellows) approaches for trans-sphenoidal pituitary surgery and cervical spine injection procedure...
May 11, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28489540/nonlinear-frequency-domain-analysis-of-the-transformation-of-cortical-inputs-by-a-motoneuron-pool-muscle-complex
#19
Renato Watanabe, Andre Kohn
Corticomotor coherence in the beta and/or gamma bands has been described in different motor tasks but the role of descending brain oscillations on force control has been elusive. Large-scale computational models of a motoneuron pool and the muscle it innervates have been used as tools to advance the knowledge of how neural elements may influence force control. Here we present a frequency domain analysis of a NARX model fitted to a large-scale neuromuscular model by means of generalized frequency response functions (GFRF)...
May 4, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28458564/radiobiological-evaluation-of-simultaneously-dose-escalated-versus-non-escalated-intensity-modulated-radiation-therapy-for-patients-with-upper-thoracic-esophageal-cancer
#20
Bao-Tian Huang, Li-Li Wu, Long-Jia Guo, Liang-Yu Xu, Rui-Hong Huang, Pei-Xian Lin, Jian-Zhou Chen, De-Rui Li, Chuang-Zhen Chen
OBJECTIVE: To compare the radiobiological response between simultaneously dose-escalated and non-escalated intensity-modulated radiation therapy (DE-IMRT and NE-IMRT) for patients with upper thoracic esophageal cancer (UTEC) using radiobiological evaluation. METHODS: Computed tomography simulation data sets for 25 patients pathologically diagnosed with primary UTEC were used in this study. DE-IMRT plan with an escalated dose of 64.8 Gy/28 fractions to the gross tumor volume (GTV) and involved lymph nodes from 25 patients pathologically diagnosed with primary UTEC, was compared to an NE-IMRT plan of 50...
2017: OncoTargets and Therapy
keyword
keyword
67020
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"