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https://www.readbyqxmd.com/read/28813423/health-needs-and-care-seeking-behaviours-of-yazidis-and-other-minority-groups-displaced-by-isis-into-the-kurdistan-region-of-iraq
#1
Valeria Cetorelli, Gilbert Burnham, Nazar Shabila
BACKGROUND: During the summer of 2014, ISIS overran Nineveh governorate in Northern Iraq. Yazidis and other religious minorities were subjected to brutal attacks and forced to seek refuge into the neighbouring Kurdistan Region, where they remain living in local communities or in camps. This survey provides a population-based assessment of the health needs and care seeking behaviours of Yazidis and other groups currently residing in camps. METHODS: The survey covered 13 camps managed by the Kurdish Board of Relief and Humanitarian Affairs...
2017: PloS One
https://www.readbyqxmd.com/read/28812825/evaluating-global-health-partnerships-a-case-study-of-a-gavi-hpv-vaccine-application-process-in-uganda
#2
Carol Kamya, Jessica Shearer, Gilbert Asiimwe, Emily Carnahan, Nicole Salisbury, Peter Waiswa, Jennifer Brinkerhoff, Dai Hozumi
BACKGROUND: Global health partnerships have grown rapidly in number and scope, yet there has been less emphasis on their evaluation. Gavi, the Vaccine Alliance, is one such public-private partnership; in Gavi-eligible countries partnerships are dynamic networks of immunization actors who work together to support all stages and aspects of Gavi support. This paper describes a conceptual framework - the partnership framework - and analytic approach for evaluating the perceptions of partnerships' added value as well as the results from an application to one case in Uganda...
October 26, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812589/connecting-earth-observation-to-high-throughput-biodiversity-data
#3
Alex Bush, Rahel Sollmann, Andreas Wilting, Kristine Bohmann, Beth Cole, Heiko Balzter, Christopher Martius, András Zlinszky, Sébastien Calvignac-Spencer, Christina A Cobbold, Terence P Dawson, Brent C Emerson, Simon Ferrier, M Thomas P Gilbert, Martin Herold, Laurence Jones, Fabian H Leendertz, Louise Matthews, James D A Millington, John R Olson, Otso Ovaskainen, Dave Raffaelli, Richard Reeve, Mark-Oliver Rödel, Torrey W Rodgers, Stewart Snape, Ingrid Visseren-Hamakers, Alfried P Vogler, Piran C L White, Martin J Wooster, Douglas W Yu
Understandably, given the fast pace of biodiversity loss, there is much interest in using Earth observation technology to track biodiversity, ecosystem functions and ecosystem services. However, because most biodiversity is invisible to Earth observation, indicators based on Earth observation could be misleading and reduce the effectiveness of nature conservation and even unintentionally decrease conservation effort. We describe an approach that combines automated recording devices, high-throughput DNA sequencing and modern ecological modelling to extract much more of the information available in Earth observation data...
June 22, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812049/importance-of-adiponectin-activity-in-the-pathogenesis-of-alzheimer-s-disease
#4
REVIEW
Masaaki Waragai, Gilbert Ho, Yoshiki Takamatsu, Kazunari Sekiyama, Shuei Sugama, Takato Takenouchi, Eliezer Masliah, Makoto Hashimoto
A recent study suggested that insulin resistance may play a central role in the pathogenesis of Alzheimer's disease (AD). In this regard, it is of note that upregulation of plasma adiponectin (APN), a benign adipokine that sensitizes the insulin receptor signaling pathway and suppresses inflammation, has recently been associated with the severities of amyloid deposits and cognitive deficits in the elderly, suggesting that APN may enhance the risk of AD. These results are unanticipated because AD has been linked to type II diabetes and other metabolic disorders in which hypoadiponectinemia has been firmly established, and because APN ameliorated neuropathological features in a mouse model of neurodegeneration...
August 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28810400/an-event-level-examination-of-successful-condom-negotiation-strategies-among-young-women
#5
Courtney Peasant, Erika A Montanaro, Trace S Kershaw, Gilbert R Parra, Nicole H Weiss, Jaimie P Meyer, James G Murphy, Tiarney D Ritchwood, Tami P Sullivan
This study examines the effect of condom negotiation strategies on condom use and partner type and substance use before sex as moderators of strategy effectiveness. Women reported their daily sexual behavior during the last month. Withholding sex was more strongly associated with condom use when utilized with a non-casual sex partner. Directly requesting condom use was more strongly and using deceptive reasons to influence condom use was less strongly related to condom use during substance use. Results underscore the importance of understanding the contexts in which condom negotiation strategies are successful in order to improve HIV/sexually transmitted infection prevention efforts among women...
January 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28808414/diiron-dithiolate-hydrides-complemented-with-proton-responsive-phosphine-amine-ligands
#6
Michaela R Carlson, Ryan Gilbert-Wilson, Danielle R Gray, Joyee Mitra, Thomas B Rauchfuss, Casseday P Richers
The reaction of Fe2(pdt)(CO)6 with two equivalents of Ph2PC6H4NH2 (PNH2) affords the amido hydride HFe2(pdt)(CO)2(PNH2)(PNH) {[H1H](0), pdt(2-) = CH2(CH2S(-))2}. Isolated intermediates in this conversion include Fe2(pdt)(CO)5-(κ(1)-PNH2) and Fe2(pdt)(CO)4(κ(2)-PNH2). X-ray crystallographic analysis of [H1H](0) shows that the chelating amino/amido-phosphine ligands occupy trans-dibasal positions. The (31)P NMR spectrum indicates that [H1H](0) undergoes rapid proton exchange between the amido and amine centers...
July 7, 2017: European Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28807923/pbp4-mediates-%C3%AE-lactam-resistance-by-altered-function
#7
Som S Chatterjee, Liang Chen, Aubre Gilbert, Thaina M da Costa, Vinod Nair, Sandip K Datta, Barry N Kreiswirth, Henry F Chambers
Penicillin Binding Protein 4 (PBP4) can provide high-level β-lactam resistance in S. aureus A series of missense and promoter mutations associated with pbp4 were detected in strains that displayed high-level resistance. We hereby show that the missense mutations facilitate the β-lactam resistance mediated by PBP4 and the promoter mutations lead to the overexpression of pbp4 Our results also suggest a co-operative interplay between PBPs for β-lactam resistance.
August 14, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28807413/corrigendum-to-a-portable-low-cost-long-term-live-cell-imaging-platform-for-biomedical-research-and-education-biosens-bioelectron-64-2015-639-649
#8
Maria P Walzik, Verena Vollmar, Theresa Lachnit, Helmut Dietz, Susanne Haug, Holger Bachmann, Moritz Fath, Daniel Aschenbrenner, Sepideh Abolpour Mofrad, Oliver Friedrich, Daniel F Gilbert
No abstract text is available yet for this article.
August 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28807359/physical-therapy-for-fecal-incontinence-in-children-with-pelvic-floor-dyssynergia
#9
Swathi Muddasani, Amanda Moe, Caitlin Semmelrock, Caroyl Luan Gilbert, Valentine Enemuo, Eric Howard Chiou, Bruno Pedro Chumpitazi
OBJECTIVES: To determine the efficacy of physical therapy (PT) for fecal incontinence in children with pelvic floor dyssynergia (PFD). STUDY DESIGN: Retrospective chart review of children with PFD completing >1 PT session for fecal incontinence at a quaternary children's hospital. The frequency of fecal incontinence (primary outcome), constipation-related medication use, number of bowel movements (in those with <3 per week at baseline) and pelvic floor muscle (PFM) function were captured at baseline and at the final PT visit...
August 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28806092/comparable-outcomes-after-bucket-handle-meniscal-repair-and-vertical-meniscal-repair-can-be-achieved-at-a-minimum-2-years-follow-up
#10
Gilbert Moatshe, Mark E Cinque, Jonathan A Godin, Alexander R Vap, Jorge Chahla, Robert F LaPrade
BACKGROUND: Meniscal tears can lead to significant pain and disability, necessitating surgical treatment. Nondisplaced vertical tears are usually smaller in size and can be repaired in most cases; however, bucket-handle tears are usually larger and displaced, and the repair of these tears can be challenging. Purpose/Hypothesis: The purpose was to report the outcomes after inside-out vertical mattress suture meniscal repair of bucket-handle tears and to compare these outcomes with those of patients who underwent repair of nondisplaced vertical meniscal tears with a minimum of 2 years' follow-up...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28804696/neonatal-safety-information-reported-to-the-fda-during-drug-development-studies
#11
Debbie Avant, Gerri Baer, Jason Moore, Panli Zheng, Alfred Sorbello, Ron Ariagno, Lynne Yao, Gilbert J Burckart, Jian Wang
BACKGROUND: Relatively few neonatal drug development studies have been conducted, but an increase is expected with the enactment of the Food and Drug Administration Safety and Innovation Act (FDASIA). Understanding the safety of drugs studied in neonates is complicated by the unique nature of the population and the level of illness. The objective of this study was to examine neonatal safety data submitted to the FDA in studies pursuant to the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) between 1998 and 2015...
2017: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/28803513/mechanisms-of-unexpected-death-and-autopsy-findings-in-friedreich-ataxia
#12
Roger W Byard, John D Gilbert
A 36-year-old woman with a clinical history of Friedreich ataxia and hypertrophic cardiomyopathy was found unexpectedly dead at her home. The heart showed asymmetric left ventricular hypertrophy, with an interventricular septal thickness of 20-25 mm (the remainder of the left ventricular wall measured 15 mm). Histologically, both ventricles had irregular areas of marked myocyte hypertrophy with associated interstitial fibrosis and focal myofibre disarray. There was neuronal loss within the dentate nucleus of the cerebellum, with vacuolation and axonal loss in the dorsal columns and spinocerebellar tracts of the upper cervical spinal cord...
January 1, 2017: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/28802585/genomics-of-the-new-species-kingella-negevensis-diagnostic-issues-identification-of-a-locus-encoding-a-rtx-toxin
#13
Onya Opota, Sacha Laurent, Trestan Pillonel, Marie Léger, Sabrina Trachsel, Guy Prod'hom, Katia Jaton, Gilbert Greub
Kingella kingae, producing the cytotoxic RTX protein, is a causative agent of serious infections in humans such as bacteremia, endocarditis and osteoarticular infection, especially in young children. Recently, Kingella negevensis, a related species, has been isolated from the oral cavity of healthy children. In this study, we report the isolation of K. negevensis strain eburonensis, initially misidentified as K. kingae with MALDI-TOF MS, from a vaginal specimen of a patient suffering of vaginosis. The genome sequencing and analysis of this strain together with comparative genomics of the Kingella genus revealed that K...
August 9, 2017: Microbes and Infection
https://www.readbyqxmd.com/read/28800886/corrigendum-to-towards-in-vitro-dt-dnt-testing-assaying-chemical-susceptibility-in-early-differentiating-nt2-cells-toxicology-338-2015-69-76
#14
Ann-Katrin Menzner, Sepideh Abolpour Mofrad, Oliver Friedrich, Daniel F Gilbert
No abstract text is available yet for this article.
August 8, 2017: Toxicology
https://www.readbyqxmd.com/read/28798878/treatment-of-knee-osteochondral-lesions-using-a-novel-clot-of-autologous-plasma-rich-in-growth-factors-mixed-with-healthy-hyaline-cartilage-chips-and-intra-articular-injection-of-prgf
#15
Ramón Cugat, Eduard Alentorn-Geli, Gilbert Steinbacher, Pedro Álvarez-Díaz, Xavier Cuscó, Roberto Seijas, David Barastegui, Jordi Navarro, Patricia Laiz, Montserrat García-Balletbó
Knee cartilage or osteochondral lesions are common and challenging injuries. To date, most symptomatic lesions warrant surgical treatment. We present two cases of patients with knee osteochondral defects treated with a one-step surgical procedure consisting of an autologous-based matrix composed of healthy hyaline cartilage chips, mixed plasma poor-rich in platelets clot, and plasma rich in growth factors (PRGF). Both patients returned to playing soccer at the preinjury activity level and demonstrated excellent defect filling in both magnetic resonance imaging and second-look arthroscopy (in one of them)...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28797571/epidemiology-of-burn-patients-presenting-to-a-tertiary-hospital-emergency-department-in-lebanon
#16
Abou Dagher Gilbert, Eva Rajha, Christopher El Khuri, Ralph Bou Chebl, Aurelie Mailhac, Maha Makki, Mazen El Sayed
BACKGROUND: The epidemiology of burns is well described in the United States, Europe and Asia. However, few studies address this topic in the Levant region. This study aims to describe characteristics of burn victims treated at the emergency department of a tertiary care center in Beirut, Lebanon and to report on factors that affect ED disposition. METHODS: A retrospective cohort study was conducted in the ED of a tertiary care hospital, in Beirut, Lebanon, between 2009 and 2013...
August 7, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28797546/cell-free-deoxyribonucleic-acid-as-a-prognostic-marker-of-bowel-ischemia-in-patients-with-small-bowel-obstruction
#17
Uri Netz, Zvi Perry, Solly Mizrahi, Boris Kirshtein, David Czeiger, Gilbert Sebbag, Avraham Reshef, Amos Douvdevani
BACKGROUND: Patients with strangulation small bowel obstruction are at a high risk for serious morbidity and mortality due to ischemic bowel. Measuring serum, cell-free deoxyribonucleic acid levels could help recognize early cell death. Our hypothesis was that small bowel ischemia or necrosis is associated with increases in serum cell-free deoxyribonucleic acid and that recovery is associated with a decrease in cell-free deoxyribonucleic acid levels. METHODS: A prospective cohort study in addition to standard treatment of patients admitted with a diagnosis of small bowel obstruction...
August 7, 2017: Surgery
https://www.readbyqxmd.com/read/28796200/new-infant-cranium-from-the-african-miocene-sheds-light-on-ape-evolution
#18
Isaiah Nengo, Paul Tafforeau, Christopher C Gilbert, John G Fleagle, Ellen R Miller, Craig Feibel, David L Fox, Josh Feinberg, Kelsey D Pugh, Camille Berruyer, Sara Mana, Zachary Engle, Fred Spoor
The evolutionary history of extant hominoids (humans and apes) remains poorly understood. The African fossil record during the crucial time period, the Miocene epoch, largely comprises isolated jaws and teeth, and little is known about ape cranial evolution. Here we report on the, to our knowledge, most complete fossil ape cranium yet described, recovered from the 13 million-year-old Middle Miocene site of Napudet, Kenya. The infant specimen, KNM-NP 59050, is assigned to a new species of Nyanzapithecus on the basis of its unerupted permanent teeth, visualized by synchrotron imaging...
August 9, 2017: Nature
https://www.readbyqxmd.com/read/28795825/development-and-validation-of-the-forms-of-self-criticizing-attacking-and-self-reassuring-scale-short-form
#19
Marion Sommers-Spijkerman, Hester Trompetter, Peter Ten Klooster, Karlein Schreurs, Paul Gilbert, Ernst Bohlmeijer
Studies investigating the effectiveness of compassion-focused therapy (CFT) are growing rapidly. As CFT is oriented toward helping people deal with internal processes of self-to-self-relating, having instruments to measure these processes is important. The 22-item Forms of Self-Criticizing/Attacking and Self-Reassuring Scale (FSCRS) has been found a useful measure. In the present study, a 14-item short form of the FSCRS (FSCRS-SF) suited to studies requiring brief measures was developed and tested in a Dutch community sample (N = 363), and cross-validated in a sample consisting of participants in a study on the effectiveness of a guided self-help compassion training (N = 243)...
August 10, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28795719/titanium-redox-catalysis-insights-and-applications-of-an-earth-abundant-base-metal
#20
Zachary W Davis-Gilbert, Ian A Tonks
π-Acid ancillary ligands, reactants, or products can stabilize reactive low valent Ti intermediates through backbonding, and present opportunities for the development of vast new classes of Ti-catalyzed redox reactions with practical applications.
August 10, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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