Annelien E Laeijendecker, Mary-Ann El Sharouni, Nikolaos Stathonikos, Clothaire P E Spoto, Bart A van de Wiel, Erik J E Eijken, Marijne Mulder, Antien L Mooyaart, Anna Szumera-Cieckiewicz, Daniela Mihic-Probst, Daniela Massi, Martin Cook, Senada Koljenovic, Llucia Alos, Paul J van Diest, Alexander C J van Akkooi, Willeke Blokx
Identification of sentinel node (SN) metastases can set the adjuvant systemic therapy indication for stage III melanoma patients. For stage IIIA patients, a 1.0 mm threshold for the largest SN tumour diameter is used. Therefore, uniform reproducible measurement of its size is crucial. At present, the number of deposits or their microanatomical sites are not part of the inclusion criteria for adjuvant treatment. The goal of the current study was to show examples of the difficulty of measuring SN melanoma tumour diameter and teach how it should be measured...
February 20, 2024: Journal of Clinical Pathology