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https://www.readbyqxmd.com/read/28428659/subcapsular-splenic-hematoma-and-spontaneous-hemoperitoneum-in-a-cocaine-user
#1
Bruno Niemeyer de Freitas Ribeiro, Rafael Santos Correia, Tiago Medina Salata, Fernanda Salata Antunes, Edson Marchiori
No abstract text is available yet for this article.
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28418840/distinct-mdct-imaging-features-to-differential-diagnosis-of-hepatic-paragonimiasis-and-small-hepatocellular-carcinoma
#2
Sheng Zhang, Si-Ming Xie, Yong-Hua Chen, Xu-Bao Liu, Gang Mai
We used multi-row detector computed tomography (MDCT) to identify the distinguishing characteristics of hepatic paragonimiasis and small hepatocellular carcinoma lesions. We analyzed a cohort of 60 patients, of which 26 had hepatic paragonimiasis and 34 with a small (≤ 3cm) hepatocellular carcinoma. MDCT detected 65 lesions that were retrospectively reviewed and analyzed based on their imaging features. Both groups showed distinct MDCT imaging features that could contribute to an accurate diagnosis. In the paragonimiasis group, 75% (21/28) lesions were located in the hepatic subcapsular region, whereas only 10...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413650/clinical-features-of-hemodialysis-patients-treated-for-hepatocellular-carcinoma-comparison-between-resection-and-radiofrequency-ablation
#3
Atsushi Hiraoka, Takashi Kumada, Kojiro Michitaka, Hidenori Toyoda, Toshifumi Tada, Koichi Takaguchi, Kunihiko Tsuji, Ei Itobayashi, Daichi Takizawa, Masashi Hirooka, Yohei Koizumi, Hironori Ochi, Koji Joko, Yoshiyasu Kisaka, Yuko Shimizu, Kazuto Tajiri, Joji Tani, Tatsuya Taniguchi, Akiko Toshimori, Shinichi Fujioka
There is no consensus regarding which therapeutic option is better and/or safer for treating hemodialysis (HD) patients with hepatocellular carcinoma (HCC). The present study compared surgical resection (Hx) and radiofrequency ablation (RFA) with regard to therapeutic efficacy in HD patients with HCC. Of 108 HD patients with naïve HCC treated at 15 institutions between 1988 and 2014 enrolled in the present study, 58 fulfilled the up-to-7 criteria [7 as the sum of the size of the largest tumor (cm) and the number of tumors] and were treated with Hx (n=23) or RFA (n=35); their clinical features, complications and prognosis were assessed...
April 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28399936/transient-bilateral-cataract-during-intensive-glucose-control-a-case-report
#4
Jung Hyun Park
BACKGROUND: Cataracts are generally known to occur in hyperglycemic conditions in diabetic patients. In this case, cataract occurred in the course of glucose level control in a patient who had been in a hyperglycemic state. CASE PRESENTATION: A 42-year-old Korean man who had uncontrolled diabetes for more than a year presented with bilateral posterior subcapsular cataracts, which developed within days of initiating antihyperglycemic therapy. With control of his serum glucose level for several weeks, the cataracts regressed...
April 12, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28391646/factors-affecting-signal-strength-in-spectral-domain-optical-coherence-tomography
#5
Ryan Lee, Yih-Chung Tham, Carol Y Cheung, Elizabeth Sidhartha, Rosalynn Grace Siantar, Sing-Hui Lim, Tien Yin Wong, Ching-Yu Cheng
PURPOSE: To identify ocular factors that affect signal strength in spectral-domain optical coherence tomography (SD-OCT). METHODS: Data from 1312 participants of the population-based Singapore Malay Eye Study-2 (SiMES-2) were included in the analysis. All participants underwent standardized ophthalmic examination, including measurements of best-corrected visual acuity (BCVA), refractive error, axial length, corneal curvature and presence of cataracts. Optic disc and macular cube scans were acquired using the Cirrus HD-OCT (software version 6...
April 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28386245/molecular-mechanisms-of-stem-progenitor-cell-maintenance-in-the-adrenal-cortex
#6
REVIEW
Antonio Marcondes Lerario, Isabella Finco, Christopher LaPensee, Gary Douglas Hammer
The adrenal cortex is characterized by three histologically and functionally distinct zones: the outermost zona glomerulosa (zG), the intermediate zona fasciculata, and the innermost zona reticularis. Important aspects of the physiology and maintenance of the adrenocortical stem/progenitor cells have emerged in the last few years. Studies have shown that the adrenocortical cells descend from a pool of progenitors that are localized in the subcapsular region of the zG. These cells continually undergo a process of centripetal displacement and differentiation, which is orchestrated by several paracrine and endocrine cues, including the pituitary-derived adrenocorticotrophic hormone, and angiotensin II...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28374150/transplantation-of-bone-marrow-derived-mscs-improves-renal-function-and-na-k-atpase-activity-in-rats-with-renovascular-hypertension
#7
Rafaelle Lira, Mariana Oliveira, Marcela Martins, Caroline Silva, Simone Carvalho, Ana Carolina Stumbo, Erika Cortez, Karine Verdoorn, Marcelo Einicker-Lamas, Alessandra Thole, Laís de Carvalho
Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation; it can be experimentally induced by the 2 Kidneys-1 Clip (2K1C) model. This study investigates the therapeutic potential of renal subcapsular mesenchymal stem cell (MSC) infusion in 2K1C rats...
April 3, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28365958/lymph-node-metastases-in-clinically-n0-patients-with-papillary-thyroid-microcarcinomas-a-single-institution-experience
#8
Merima Goran, Tatjana Pekmezovic, Ivan Markovic, Nada Santrac, Marko Buta, Dusica Gavrilovic, Nikola Besic, Yasuhiro Ito, Igor Djurisic, Gordana Pupic, Radan Dzodic
PURPOSE: To register the frequency of central and lateral lymph node metastases (LNMs) from papillary thyroid microcarcinomas (PTMCs), and to assess whether sentinel lymph node (SLN) biopsy of the lateral compartment is an accurate technique to select patients with true positive but clinically negative lymph nodes for one-time selective lateral neck dissection (sLND). The correlation between tumor characteristics (size, multifocality, bilaterality, capsular invasion) and LNMs was analyzed...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28365272/erk1-2-signaling-is-required-for-the-initiation-but-not-progression-of-tgf%C3%AE-induced-lens-epithelial-to-mesenchymal-transition-emt
#9
Magdalena C Wojciechowski, Leila Mahmutovic, Daisy Y Shu, Frank J Lovicu
Transforming Growth Factor Beta (TGFβ) potently induces lens epithelial to mesenchymal transition (EMT). The resultant mesenchymal cells resemble those found in plaques of human forms of subcapsular cataract. Smad signaling has long been implicated as the sole driving force of TGFβ-mediated activity. Rat lens epithelial explants were used to examine the role of the Smad-independent signaling, namely the MAPK/ERK1/2 signaling pathway, in the initiation and progression of TGFβ-induced EMT. Phase contrast microscopy was used to observe the morphological changes associated with TGFβ-induced EMT in this model, including cell elongation, cell membrane blebbing, cell loss as indicated by the area of bare capsule and capsular wrinkling...
March 30, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28344873/a-specific-immune-and-lymphatic-profile-characterizes-the-pre-metastatic-state-of-the-sentinel-lymph-node-in-patients-with-early-cervical-cancer
#10
Cédric Balsat, Silvia Blacher, Michael Herfs, Maureen Van de Velde, Nicolas Signolle, Philippe Sauthier, Charles Pottier, Stéphanie Gofflot, Marjolein De Cuypere, Philippe Delvenne, Frédéric Goffin, Agnès Noel, Frédéric Kridelka
The lymph node (LN) pre-metastatic niche is faintly characterized in lymphophilic human neoplasia, although LN metastasis is considered as the strongest prognostic marker of patient survival. Due to its specific dissemination through a complex bilateral pelvic lymphatic system, early cervical cancer is a relevant candidate for investigating the early nodal metastatic process. In the present study, we analyzed in-depth both the lymphatic vasculature and the immune climate of pre-metastatic sentinel LN (SLN), in 48 cases of FIGO stage IB1 cervical neoplasms...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28340314/ocular-manifestations-in-children-with-juvenile-onset-systemic-lupus-erythematosus
#11
Ghada Gawdat, Dina El-Fayoumi, Huda Marzouk, Yomna Farag
PURPOSE: To study the ocular manifestations of juvenile systemic lupus erythematosus (JSLE), including the ocular side-effects of the systemic medications used. METHODS: A descriptive cross-sectional study on 40 children diagnosed with JSLE was conducted. Ophthalmological and laboratory investigations as well as a calculation of the Systemic Lupus Disease Activity Index 2000 (SLEDAI-2K) were performed. RESULTS: Forty consecutive children, 32 females and 8 males, with JSLE were examined...
March 24, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28333188/autologous-collagen-matrix-acm-lower-pole-support-with-a-supero-anterior-capsular-flap-in-secondary-subpectoral-breast-augmentation
#12
Paolo Montemurro, Mubashir Cheema, Per Hedén, Stefano Avvedimento, Mouchammed Agko, Alessandro Quattrini Li
Background: Secondary aesthetic breast surgery is a complex and challenging scenario. It requires the surgeon to identify contributing factors, provide patient education, make a further management plan, and optimize the conditions for a favorable result. Various techniques have been described in literature but the rate of reoperation is still high. The first author has been using a supero-anterior capsular flap with a neopectoral subcapsular pocket and an implant change in these cases...
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28328621/ocular-involvement-in-children-with-inflammatory-bowel-disease
#13
Samuele Naviglio, Fulvio Parentin, Silvia Nider, Nicolò Rassu, Stefano Martelossi, Alessandro Ventura
BACKGROUND: Data on ocular manifestations of inflammatory bowel disease (IBD) in children are limited. Some authors have reported a high prevalence of asymptomatic uveitis, yet the significance of these observations is unknown and there are no recommendations on which ophthalmologic follow-up should be offered. METHODS: Children with IBD seen at a single referral center for pediatric gastroenterology were offered ophthalmologic evaluation as part of routine care for their disease...
March 21, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28319345/percutaneous-microwave-ablation-of-exophytic-tumours-in-hepatocellular-carcinoma-patients-safe-or-not
#14
Jianmin Ding, Yan Zhou, Yandong Wang, Xiang Jing, Fengmei Wang, Yijun Wang
BACKGROUND & AIMS: To explore the long-term outcomes and safety of ultrasound-guided percutaneous microwave ablation (MWA) of exophytic tumours in hepatocellular carcinoma (HCC) patients. METHODS: One hundred and thirty-two patients with subcapsular HCC were enrolled in this retrospective study. These patients were divided into the exophytic group (n=71) and non-exophytic group (n=61) according to the location of the tumour(s). A special technology of puncture and ablation was performed to treat the exophytic tumours...
March 20, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28297566/instructive-role-of-the-microenvironment-in-preventing-renal-fibrosis
#15
Kei Matsumoto, Sandhya Xavier, Jun Chen, Yujiro Kida, Mark Lipphardt, Reina Ikeda, Annie Gevertz, Mario Caviris, Antonis K Hatzopoulos, Ivo Kalajzic, James Dutton, Brian B Ratliff, Hong Zhao, Zbygniew Darzynkiewicz, Stefan Rose-John, Michael S Goligorsky
Accumulation of myofibroblasts is a hallmark of renal fibrosis. A significant proportion of myofibroblasts has been reported to originate via endothelial-mesenchymal transition. We initially hypothesized that exposing myofibroblasts to the extract of endothelial progenitor cells (EPCs) could reverse this transition. Indeed, in vitro treatment of transforming growth factor-β1 (TGF-β1)-activated fibroblasts with EPC extract prevented expression of α-smooth muscle actin (α-SMA); however, it did not enhance expression of endothelial markers...
March 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28291554/implantation-of-posterior-chamber-phakic-intraocular-lens-for-myopia-and-hyperopia%C3%A2-%C3%A2-long-term-clinical-outcomes
#16
H Kocová, E Vlková, L Michalcová, O Motyka
PURPOSE: To evaluate long-term refractive outcomes of implantable collamer lens (ICL) implantation and late postoperative complications. METHODS: We assessed outcomes of patients who underwent ICL implantation (type ICM V4 for myopia, ICH V3 for hyperopia, TICM V4 for astigmatism) in our department between 1998 and 2013. It comprised 62 eyes (40 myopic and 22 hyperopic). The average follow-up period was 10.5 years. We evaluated: uncorrected and best-corrected visual acuity (UCVA and BCVA), spherical equivalent (SE), ICL vault, endothelial cell density and late postoperative complications...
March 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28283911/recovery-of-renal-function-after-administration-of-adipose-tissue-derived-stromal-vascular-fraction-in-rat-model-of-acute-kidney-injury-induced-by-ischemia-reperfusion-injury
#17
Chunwoo Lee, Myoung Jin Jang, Bo Hyun Kim, Jin Young Park, Dalsan You, In Gab Jeong, Jun Hyuk Hong, Choung-Soo Kim
Acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) injury is a major challenge in critical care medicine. The purpose of this study is to determine the therapeutic effects of the adipose-tissue-derived stromal vascular fraction (SVF) and the optimal route for SVF delivery in a rat model of AKI induced by I/R injury. Fifty male Sprague-Dawley rats were randomly divided into five groups (10 animals per group): sham, nephrectomy control, I/R injury control, renal arterial SVF infusion and subcapsular SVF injection...
March 10, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28273370/features-of-papillary-thyroid-microcarcinoma-associated-with-lateral-cervical-lymph-node-metastasis
#18
Min Ji Jeon, Mi Sun Chung, Hyemi Kwon, Mijin Kim, Suyeon Park, Jung Hwan Baek, Dong Eun Song, Tae-Yon Sung, Suck Joon Hong, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Jeong Hyun Lee, Won Gu Kim
OBJECTIVES: Papillary thyroid microcarcinoma (PTMC) has an excellent prognosis with an indolent disease course. However, some PTMCs have an aggressive course with lateral cervical lymph node (LCLN) metastasis or distant metastasis. This study aimed to evaluate the pre-operative features of PTMC associated with LCLN metastasis. DESIGN AND PATIENTS: This retrospective cohort study with a nested, matched case-control design included 199 PTMC patients with LCLN metastasis at initial surgery (N1b group) and 196 PTMC patients without any LN metastasis or persistent disease (N0 NED group) as controls; primary tumour sizes were matched...
March 8, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28271519/bilateral-massive-perirenal-subcapsular-effusion-a-case-report
#19
Sercan Yilmaz, Murat Zor, Mehmet Ersan, Salih Hamcan
Bilateral perirenal subcapsular effusion is a rare condition with several underlying etiologies. A 27-year-old woman presented with a 3-day history of bilateral flank pain and edema on the dorsum of her feet. Imaging, biochemical, and clinical evaluations revealed bilateral massive perirenal subcapsular effusion secondary to nephrotic syndrome. The patient was successfully treated with bilateral percutaneous drainage. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound, 2017.
March 8, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28257871/effect-of-early-pregnancy-on-the-expression-of-progesterone-receptor-and-progesterone-induced-blocking-factor-in-ovine-lymph-node
#20
Ling Yang, Shengqin Zang, Ying Bai, Xiaolei Yao, Leying Zhang
Lymph nodes are the sites where the immune reaction or suppression takes place. Progesterone (P4) exerts an essential effect of the immunomodulation on the maternal uterus during early pregnancy in ruminants. At present study, the inguinal lymph nodes were obtained at day 16 of non-pregnancy, days 13, 16 and 25 of pregnancy (n = 3 for each group) in ewes, and RT-PCR assay, western blot and immunohistochemistry analysis were used to analyze to the effect of early pregnancy on the expression of P4 receptor (PGR) and progesterone-induced blocking factor (PIBF) in the lymph nodes...
April 15, 2017: Theriogenology
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