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https://www.readbyqxmd.com/read/29141386/-clinical-characteristics-and-surgical-effect-observation-of-congenital-aniridia-combined-with-cataract
#1
X H Wu, Q Z Cao, Y X Hu, J N Lin, H T Lin, W R Chen, Y Z Liu
Objective: To analyze the clinical manifestations, surgical approaches and postoperative prognosis for the cases of congenital aniridia combined with cataract. Methods: In this retrospective case series, 26 patients diagnosed with congenital aniridia combined with cataract were collected from Zhongshan Ophthalmic Center from February 2002 to August 2016. The Clinical data were collected to analyze the clinical features, surgical approaches and postoperative prognosis. T-test was used for statistical analysis...
November 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29127310/wavefront-aberrations-and-retinal-image-quality-in-different-lenticular-opacity-types-and-densities
#2
Cheng-Zhe Wu, Hua Jin, Zhen-Nv Shen, Ying-Jun Li, Xun Cui
To investigate wavefront aberrations in the entire eye and in the internal optics (lens) and retinal image qualities according to different lenticular opacity types and densities. Forty-one eyes with nuclear cataract, 33 eyes with cortical cataract, and 29 eyes with posterior subcapsular cataract were examined. In each group, wavefront aberrations in the entire eye and in the internal optics and retinal image quality were measured using a raytracing aberrometer. Eyes with cortical cataracts showed significantly higher coma-like aberrations compared to the other two groups in both entire eye and internal optic aberrations (P = 0...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29118503/inadvertent-intralenticular-dexamethasone-implant-1-year-follow-up-and-management
#3
Cagatay Caglar
We report the case of a 72-year-old female who developed macular edema (ME) due to hemicentral retinal vein occlusion in her right eye. A dexamethasone implant was inadvertently injected into the crystalline lens. The patient was followed without repositioning of the dexamethasone implant during the 12 months. Besides, the posterior subcapsular cataract and ME had progressed significantly; hence, cataract extraction and intravitreal ranibizumab injection were performed in the same session. A three-piece intraocular lens was implanted in the sulcus with optic captured, and then intravitreal ranibizumab injection was performed...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29117926/-maternal-deaths-due-to-hypertensive-disorders-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#4
M Dreyfus, P Weber, L Zieleskiewicz
Between 2010 and 2012, the rate of maternal death caused by hypertensive disorders (0,5/100,000 living birth) was reduced by 50% compared to the 2007-2009 period. Hypertensive disorders were responsible from 5% of maternal deaths and from 10% of direct maternal mortality. Eleven deaths happened during the postpartum period but 9 hypertensive complications began before delivery. Seventy percent of these deaths seem to be avoidable. The main causes of suboptimal management were: unappropriated or insufficient obstetrical and anesthetic treatments, undiagnosed HELLP syndrome and subcapsular liver hematoma, delayed treatment...
November 5, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29110086/acute-and-chronic-fluid-misdirection-syndrome-pathophysiology-and-treatment
#5
Andrzej Grzybowski, Piotr Kanclerz
PURPOSE: To summarize our current understanding of the specific pathogenic mechanisms of the fluid misdirection syndrome and possible treatment methods. METHODS: We used the PubMed web platform to find relevant studies using the following keywords: infusion misdirection syndrome, aqueous misdirection syndrome, ciliary block, ciliovitreal block, capsular block, intraoperative fluid misdirection, subcapsular fluid entrapment, acute intraoperative rock-hard eye syndrome, positive vitreous pressure glaucoma, and malignant glaucoma...
November 6, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29101181/endothelial-dysfunction-is-a-super-inducer-of-syndecan-4-fibrogenic-role-of-its-ectodomain
#6
Mark Lipphardt, Jong W Song, Brian B Ratliff, Hassan Dihazi, Gerhard A Müller, Michael S Goligorsky
Syndecan 4 (Synd4) is a member of membrane-spanning, glycocalyx-forming proteoglycan family. It has been suggested that Synd4 participates in renal fibrosis. We compared wild type and fibrosis-prone endothelial sirtuin1-deficient (Sirt1(endo)-/-) mice, the latter being a model of global endothelial dysfunction. We performed mass-spectrometry analysis, which revealed that Synd4 was highly enriched in the secretome of renal microvascular endothelial cells (RMVEC) obtained from Sirt1(endo)-/- mice upon stimulation with TGFβ1; notably all detectable peptides were confined to the ectodomain of Synd4...
November 3, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29098195/subcapsular-splenic-urinoma-and-splenorenal-fistula-a-new-complication-of-percutaneous-nephrolithotomy
#7
Eugene B Cone, Ghalib Jibara, Daniel Wollin, Glenn M Preminger
Background: Splenic urinoma has not been previously reported as a complication of percutaneous nephrolithotomy (PNL). Case Presentation: A 46-year-old Caucasian male underwent PNL for two large left renal stones. Surgery was performed in prone split-leg position, with access obtained through combined fluoroscopic guidance and direct ureteroscopic observation of the targeted calix. The tract was dilated to 30F using a pressure balloon, and complete clearance of stones was obtained through a combination of rigid and flexible nephroscopy, as well as antegrade ureteroscopy...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29098192/forgotten-perinephric-drain-anchored-in-the-tissues-lessons-to-be-learned
#8
Prashant Kumar, Rishi Nayyar
Background: Drainage of any deep seated abscess often requires placement of catheters along with other conservative measures. These catheters are removed when the drainage volume reduces to clinically insignificant levels. However, if left in situ, there are potential complications. One such complication necessitating additional surgical procedure is highlighted in this case report. Malecot's catheter and children may be more at risk for such a complication. Case Presentation: A 7-year-old girl presented with recurrent episodes of right flank pain associated with high-grade fever with chills for the last 5 months and right perinephric drain in situ...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29093620/laparoscopic-finding-of-a-hepatic-subcapsular-spider-like-telangiectasis-sign-in-biliary-atresia
#9
Ying Zhou, Meng Jiang, Shao-Tao Tang, Li Yang, Xi Zhang, De-Hua Yang, Meng Xiong, Shuai Li, Guo-Qing Cao, Yong Wang
AIM: To assess the diagnostic value of a laparoscopic finding of a hepatic subcapsular spider-like telangiectasis (HSST) sign in biliary atresia. METHODS: A retrospective study was conducted first and then a validation set was used to investigate the value of an HSST sign in predicting biliary atresia (BA). In the retrospective study, laparoscopic images of the liver surface were reviewed in 126 patients with infantile cholestasis (72 BA patients and 54 non-BA cholestasis patients) and a control group of 38 patients with non-hepatic conditions...
October 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29090424/spontaneous-external-biliary-fistula-arising-from-an-intrahepatic-duct
#10
Naoto Mizumura, Satoshi Okumura, Hiroshi Tsuchihashi, Masao Ogawa, Masayasu Kawasaki
A spontaneous external biliary fistula is most commonly a cholecystocutaneous fistula secondary to acute cholecystitis. A fistula arising from an intrahepatic duct is extremely rare. An 87-year-old man presented with swelling of the epigastric region and right upper quadrant abdomen. He had a history of cholecystectomy and endoscopic sphincterotomy. After antibiotic treatment and surgical opening of both lesions, abdominal computed tomography demonstrated a soft tissue mass cephalad to the umbilicus. We excised the mass, and found it to be associated with a fistula through the linea alba...
October 31, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29065137/differences-in-the-population-structure-of-neisseria-meningitidis-in-two-australian-states-victoria-and-western-australia
#11
Shakeel Mowlaboccus, Christopher A Mullally, Peter C Richmond, Benjamin P Howden, Kerrie Stevens, David J Speers, Anthony D Keil, Ottar N Bjørnstad, Timothy T Perkins, Charlene M Kahler
Neisseria meningitidis is the causative agent of invasive meningococcal disease (IMD). A recombinant vaccine called Bexsero® incorporates four subcapsular antigens (fHbp, NHBA, NadA and PorA) which are used to assign a Bexsero® antigen sequence type (BAST) to each meningococcal strain. The vaccine elicits an immune response against combinations of variants of these antigens which have been grouped into specific BAST profiles that have been shown to have different distributions within geographical locations thus potentially affecting the efficacy of the vaccine...
2017: PloS One
https://www.readbyqxmd.com/read/29051827/membrane-like-structure-in-the-urinary-bladder-neck-of-a-young-cat-diagnosis-and-treatment-using-balloon-dilatation-and-a-balloon-expandable-metallic-stent
#12
Matias Ruiz-Drebing, Fui Yap, Mayank Seth, Ruth Dennis, Elisabet Dominguez
CASE SUMMARY: A 33-month-old, spayed female domestic shorthair cat was referred to the Animal Health Trust for the investigation of urinary incontinence and straining to urinate. A membrane-like structure was detected in the bladder neck, which caused partial obstruction of the urinary bladder. A combination of different imaging techniques, including ultrasonography, radiography, CT and fluoroscopy, was essential in the diagnosis, surgical planning and treatment of this intravesicular stricture...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/29048240/natural-course-of-posterior-subcapsular-cataract-over-a-short-time-period
#13
Thomas Neumayer, Nino Hirnschall, Michael Georgopoulos, Oliver Findl
Purpose/aim of the study: To observe and analyze the weekly changes in morphology and size of vacuoles, so called Wedl cells, in eyes with posterior subcapsular cataract (PSC). MATERIALS AND METHODS: Thirty-six eyes of 36 patients with pronounced PSC were included in this prospective study. High-resolution retroillumination images were taken, and the changes in size and shape of Wedl cells were analyzed at baseline and at 2 and 4 weeks later using dedicated imaging software. RESULTS: In total, 1087 Wedl cells were observed...
October 19, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29045971/-technical-improvement-in-retroperitoneal-laparoscopic-living-donor-nephrectomy-report-of-193-cases
#14
L Zhao, L L Ma, H X Zhang, X F Hou, L Liu, Y Fu, Y G Kou, Y M Song
OBJECTIVE: To summarize our experience of retroperitoneal laparoscopic living donor nephrectomy, our continuous technical improvements and refinement of this skill and standardization of each procedure of this operation. METHODS: Having approved by hospital ethical committee and local government administration, a total of 193 living donors underwent retroperitoneal laparoscopic living donor nephrectomy from Dec.2003 to Feb. 2016 in our department. Under general anaesthesia, the operation was performed through 3 lumbar ports...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29032692/a-post-endoscopic-retrograde-cholangiopancreatography-subcapsular-hepatic-hematoma
#15
Rocío Soler Humanes, Miguel Ángel Suárez Muñoz, Blanca García García
Nowadays endoscopic retrograde cholangiopancreatography (ERCP) is a minimally invasive technique with a complication rate around 2.5% in expert hands, being the most frequent: acute pancreatitis, cholangitis, hemorrhage and perforation. An exceptional complication is subcapsular hepatic hematoma, first published in the literature in 2000, with few cases reported. Regarding the case published by Del Moral Martínez et al (Hepatic Hematoma after ERCP: presentation of two new cases. Rev Esp Enferm Dig 2017, Vol...
November 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29031189/renal-subcapsular-xenografing-of-human-fetal-external-genital-tissue-a-new-model-for-investigating-urethral-development
#16
Dylan Isaacson, Joel Shen, Mei Cao, Adriane Sinclair, Xuan Yue, Gerald Cunha, Laurence Baskin
In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized athymic mice. The mice were treated with a subcutaneous pellet of dihydrotestosterone (DHT), diethylstilbestrol (DES) or untreated with hormones. Xenografts were harvested after fourteen days of growth and analyzed via serial histologic sectioning and immunostaining for Ki-67, cytokeratins 6, 7 and 10, uroplakin and the androgen receptor...
September 22, 2017: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/29028122/atypical-alk-positive-spitz-tumors-with-9p21-homozygous-deletion-report-of-two-cases-and-review-of-the-literature
#17
Andrew J Rand, Wendy L Flejter, Christopher A Dowling, Linda M Brooke, Genevieve M Boland, Daniela Kroshinsky, Isaac R Rosenblum, Marier Hernandez-Perez, Julie D R Reimann
ALK rearrangements occur in up to 10% of spitzoid melanocytic neoplasms. No reported cases have shown homozygous deletion of 9p21 (CDKN2A) or gains of 6p25 (RREB1) or 11q13 (CCND1), which have been associated with aggressive clinical behavior. Here we report two unique cases. Case 1 occurred in a 9-year-old male with a 14-mm nodule on the anterior left thigh. Biopsy revealed an ALK-positive Spitz tumor containing an irregular nodule of densely packed melanocytes with increased mitoses and loss of p16 immunoreactivity...
October 13, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29018756/descemet-s-stripping-automated-endothelial-keratoplasty-for-symptomatic-thioridazine-deposits-in-the-cornea
#18
Masoumeh Mohebbi, Hassan Hashemi, Alireza Mahmoudi, Pasha Anvari
The aim of this study was to use Descemet's Stripping-automated Endothelial Keratoplasty (DSAEK) as a novel treatment to remove thioridazine corneal deposits. A 53-year-old female presented with a 3-month history of visual loss and glare. She had been taking thioridazine (100 mg/day for 1 year) for a psychiatric disorder. Dense yellowish-brown deposits had developed in the posterior stroma. Thioridazine was discontinued, and she was switched to fluoxetine. One year after discontinuation of thioridazine, her symptoms and signs did not resolve...
January 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/28991611/effect-of-fixation-stability-during-biometry-measurements-on-refractive-prediction-accuracy-in-highly-myopic-eyes
#19
Xiangjia Zhu, Wenwen He, Yu Du, Yi Lu
PURPOSE: To assess the effect of preoperative biometry fixation stability on postoperative refractive errors in highly myopic cataractous eyes. SETTING: Eye and ENT Hospital of Fudan University, Shanghai, China. DESIGN: Prospective cohort study. METHODS: Eyes of highly myopic patients and emmetropic controls were included. Routine ophthalmologic examinations and measurement of fixation stability in the 63% and 95% bivariate contour ellipse areas (BCEAs) were conducted preoperatively...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28974760/immune-response-of-a-novel-atr-ap205-001-conjugate-anti-hypertensive-vaccine
#20
Xiajun Hu, Yihuan Deng, Xiao Chen, Yanzhao Zhou, Hongrong Zhang, Hailang Wu, Shijun Yang, Fen Chen, Zihua Zhou, Min Wang, Zhihua Qiu, Yuhua Liao
We developed a virus-like particle (VLP)-based therapeutic vaccine against angiotensin II receptor type 1, ATR-AP205-001, which could significantly reduce the blood pressure and protect target organs of hypertensive animals. In this study, we focused on the immunological effect and safety of the VLP-based vaccine. By comparing to the depolymerized dimeric vaccine ATR-Dimer-001, we found that ATR-AP205-001 reached subcapsular sinus of lymph node shortly after administration, followed by accumulation on follicle dendritic cells via follicle B cell transportation, while ATR-Dimer-001 vaccine showed no association with FDCs...
October 3, 2017: Scientific Reports
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