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https://www.readbyqxmd.com/read/28100939/management-of-liver-trauma-in-minia-university-hospital-egypt
#1
Abdel Fattah Saleh, Emad Al Sageer, Amr Elheny
The aim of this study is to present the outcome of operative and non-operative management of patients with liver injury treated in a single institution depending on imaging. This study was conducted at the Causality Unit of Minia University Hospital, and included 60 patients with hepatic trauma from March 2012 to January 2013. In our study, males represent 80 % while females represent 20 % of the traumatized patients. The peak age for trauma found was 11-30 years. Blunt trauma is the most common cause of liver injury as it was the cause in 48 patients (80 %)...
December 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28053303/management-of-liver-allograft-trauma-resulting-in-massive-subcapsular-hematoma-after-living-donor-liver-transplantation-can-we-salvage-the-liver-allograft
#2
Shih-Chao Hsu, Ashok Thorat, Kin-Shing Poon, Chun-Chieh Yeh, Te-Hung Chen, Horng-Ren Yang, Long-Bin Jeng
BACKGROUND Liver allograft trauma resulting in subcapsular hematoma after living donor liver transplantation (LDLT), although rare, is a life-threatening condition and requires prompt management to avoid any catastrophe. Herein we describe our successful experience in dealing with liver allograft hematoma that developed in the post-operative period after LDLT. MATERIAL AND METHODS From January 2002 to May 2015, a total of 616 recipients underwent LDLT at our institute. The intra-operative and postoperative records of these patients were analyzed to study the cases of liver allograft hematoma...
January 5, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28049374/needle-track-seeding-after-percutaneous-radiofrequency-ablation-of-hepatocellular-carcinoma-14-year-experience-at-a-single-center
#3
Zhong-Yi Zhang, Wei Yang, Kun Yan, Ying Dai, Wei Wu, Jung-Chieh Lee, Min-Hua Chen
PURPOSE: To determine the incidence, risk factors and prognosis associated with needle track seeding after percutaneous radiofrequency ablations(RFA) for hepatocellular carcinoma(HCC) with a long-term follow-up. MATERIALS AND METHODS: 741 HCC patients undergoing percutaneous RFA were retrospectively analyzed. Mean follow-up interval was 34.3±26.8 months. All seeding neoplasms were diagnosed by imaging modalities with or without pathological evaluation. Risk factors, including Child-Pugh grading, tumor size, number, location, serum AFP level, track number, biopsy before RFA and electrode type were performed by univariate analysis...
January 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28040266/angiotensin-ii-at1-receptor-signaling-is-necessary-for-cyclooxygenase-2-dependent-postnatal-nephron-generation
#4
Stefanie Frölich, Patrick Slattery, Dominique Thomas, Itamar Goren, Nerea Ferreiros, Boye L Jensen, Rolf M Nüsing
Deletion of cyclooxygenase-2 (COX-2) causes impairment of postnatal kidney development. Here we tested whether the renin angiotensin system contributes to COX-2-dependent nephrogenesis in mice after birth and whether a rescue of impaired renal development and function in COX-2(-/-) mice was achievable. Plasma renin concentration in mouse pups showed a birth peak and a second peak around day P8 during the first 10 days post birth. Administration of the angiotensin II receptor AT1 antagonist telmisartan from day P1 to P3 did not result in cortical damage...
December 28, 2016: Kidney International
https://www.readbyqxmd.com/read/28005587/diagnosis-and-management-of-hellp-syndrome-complicated-by-liver-hematoma
#5
Agnès Ditisheim, Baha M Sibai
Subcapsular liver hematoma is a rare but potentially life-threatening complication of preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. It may present with nonspecific signs and symptoms, none of which are diagnostic, and can mimic pulmonary embolism of cholecystitis. There is no consensus on the management of subcapsular liver hematoma. Unruptured liver hematoma can be conservatively managed. When rupture occurs, surgical, endovascular approaches and, rarely, liver transplantation, may be required...
December 21, 2016: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28004996/splenic-subcapsular-hematoma-after-endoscopic-retrograde-cholangiopancreatography-in-a-liver-transplant-recipient-case-report-and-literature-review
#6
Martin Montenovo, Emran Javed, Ramasamy Bakthavatsalam, Jorge Reyes
Splenic injuries after an endoscopic retrograde cholangiopancreatography are a rare but lethal complication. We describe a subcapsular splenic hematoma requiring emergent splenectomy after an endoscopic retrograde cholangiopancreatography in a liver transplant recipient.
December 22, 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27999887/imaging-patterns-and-focal-lesions-in-fatty-liver-a-pictorial-review
#7
REVIEW
Sudhakar K Venkatesh, Tiffany Hennedige, Geoffrey B Johnson, David M Hough, Joel G Fletcher
Non-alcoholic fatty liver disease is the most common cause of chronic liver disease and affects nearly one-third of US population. With the increasing trend of obesity in the population, associated fatty change in the liver will be a common feature observed in imaging studies. Fatty liver causes changes in liver parenchyma appearance on imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and may affect the imaging characteristics of focal liver lesions (FLLs)...
December 20, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27998312/rare-presentation-of-subcapsular-hepatic-steatosis-in-a-woman-with-uncontrolled-diabetes-without-peritoneal-dialysis-a-case-report
#8
Varun Chowdhary, Jennifer S Golia Pernicka, Richa Sharma
BACKGROUND: Subcapsular hepatic steatosis is a rare atypical pattern of fatty deposition of the liver reported in patients with diabetic nephropathy receiving peritoneal dialysis with intraperitoneal insulin. To date, there has been only one pediatric and zero adult cases of subcapsular hepatic steatosis with no history of continuous ambulatory peritoneal dialysis. We report the first published case of subcapsular hepatic steatosis in an adult diabetic patient without any history of peritoneal dialysis or evidence of chronic renal disease...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27986963/eye-lens-radiation-exposure-in-greek-interventional-cardiology-article
#9
Zoi Thrapsanioti, Panagiotis Askounis, Ioannis Datseris, Ramza Anastasia Diamanti, Miltiadis Papathanasiou, Eleftheria Carinou
The lens of the eye is one of the radiosensitive tissues of the human body; if exposed to ionizing radiation can develop radiation-induced cataract at early ages. This study was held in Greece and included 44 Interventional Cardiologists (ICs) and an unexposed to radiation control group of 22 persons. Of the note, 26 ICs and the unexposed individuals underwent special eye examinations. The detected lens opacities were classified according to LOCS III protocol. Additionally, the lens doses of the ICs were measured using eye lens dosemeters...
December 15, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27986169/hepatic-steatosis-etiology-patterns-and-quantification
#10
Ilkay S Idilman, Ilknur Ozdeniz, Musturay Karcaaltincaba
Hepatic steatosis can occur because of nonalcoholic fatty liver disease (NAFLD), alcoholism, chemotherapy, and metabolic, toxic, and infectious causes. Pediatric hepatic steatosis is also becoming more frequent and can have distinctive features. The most common pattern is diffuse form; however, it can present in heterogenous, focal, multinodular, perilesional, perivascular, subcapsular, and lobar forms. Focal steatosis and fat sparing can occur because of the presence of veins of Sappey, pancreaticoduodenal vein, and aberrant right and left gastric veins, which drain into the liver as third inflow...
December 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27979014/inhaled-corticosteroids-ocular-safety-and-the-hypothalamic-pituitary-adrenal-axis
#11
Warner W Carr, Stanley J Szefler
BACKGROUND: Inhaled corticosteroids (ICSs) effectively deliver corticosteroids to target sites in the lungs and reduce systemic effects compared with oral corticosteroids, but long-term systemic exposure from inhaled corticosteroids remains a concern. OBJECTIVE: To discuss ICS systemic effects on the eye and the hypothalamic-pituitary-adrenal (HPA) axis. METHODS: Relevant publications were used to augment discussion. RESULTS: The most common adverse effects of exogenous corticosteroids on the eye are secondary open-angle glaucoma and posterior subcapsular cataracts...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27957298/resolution-of-bile-duct-adenoma-over-follow-up-period-a-case-report
#12
Mitra Ahadi, Ahmad Khosravi Khorashad, Hassan Saadatnia, Hassan Vosoughinia, Behrooz Davachi, Mohammadreza Farzanehfar, Kamran Ghaffarzadehgan, Bahram Memar, Elham Mokhtari Amirmajdi
Bile duct adenoma (BDA) is a rare neoplasm of bile ducts with various clinical manifestations and imaging appearances. A few cases of BDA and their predisposing factors have been described. We report a 35-year-old woman with right upper quadrant pain who consumed oral contraceptive pills. Ultrasound study revealed three hypoechoic subcapsular liver masses; two of them were hypodense in computed tomography. Fine needle biopsy of the largest mass showed bile duct adenoma. Liver masses disappeared after discontinuing the pills over a 2-year follow-up...
October 2016: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27939836/luteinizing-hormone-releasing-hormone-agonists-are-superior-to-subcapsular-orchiectomy-in-lowering-testosterone-levels-of-men-with-prostate-cancer-results-from-a-randomized-clinical-trial
#13
Peter B Østergren, Caroline Kistorp, Mikkel Fode, James Henderson, Finn N Bennedbæk, Jens Faber, Jens Sønksen
PURPOSE: Recent evidence suggests that reaching the lowest achievable levels of testosterone with androgen deprivation therapy delays disease progression and increases overall survival in men with advanced prostate cancer. The aim of this analysis is to compare the post-treatment serum testosterone levels between patients undergoing subcapsular orchiectomy and patients treated with the luteinizing hormone-releasing hormone agonist triptorelin. MATERIAL AND METHODS: In this randomized clinical trial, we included 58 consecutive hormone-naive men diagnosed with advanced prostate cancer at Herlev and Gentofte University Hospital, Denmark, from September 2013 to March 2015...
December 8, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27936471/prevalence-of-lens-opacities-in-adult-chinese-americans-the-chinese-american-eye-study-ches
#14
Rohit Varma, Jie Sun, Mina Torres, Shuang Wu, Chunyi Hsu, Stanley Paul Azen, Roberta McKean-Cowdin
Purpose: We determined the age- and sex-specific prevalence of posterior subcapsular (PSC), nuclear, cortical, and mixed lens opacities in a population-based sample of Chinese-American adults. Methods: A population-based sample of Chinese-Americans 50 years and older, from 10 census tracts in Monterey Park, CA, USA, underwent a detailed interview and a comprehensive clinical examination that included assessment of different types of lens opacities by the slit-lamp-based Lens Opacities Classification System II (LOCS II)...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27932439/management-of-splenic-ectopic-pregnancy-presenting-with-massive-haemoperitoneum
#15
Alissa Greenbaum, Richard Miskimins, Brittany Coffman, Jasmeet Paul
Abdominal ectopic pregnancy (EP) accounts for only 1.3% of EPs and occurs when a fertilised ovum implants in an extrapelvic peritoneal location. Primary splenic pregnancy is a rare type of abdominal EP, with only 16 cases previously reported in the literature. Early diagnosis is essential as delay in treatment carries significant potential for morbidity and mortality. We present the case of a 27-year-old woman presenting with left upper quadrant abdominal pain, elevated human chorionic gonadotropin levels, absence of intrauterine gestational sac and massive haemoperitoneum on transvaginal ultrasound...
December 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27930432/retinal-findings-in-a-case-of-presumed-cutis-marmorata-telangiectatica-congenita
#16
Eman A Taleb, Manish P Nagpal, Navneet S Mehrotra, Kalyani Bhatt
PURPOSES: To correlate the clinical picture and fundus fluorescein angiography findings in case of presumed cutis marmorata telangiectatica congenita. METHODS: A 41-year-old woman with presumed cutis marmorata telangiectatica congenita who is a known case of hypothyroidism for the last 6 years and has bilateral peripheral retinal vascular abnormalities, peripheral retinal nonperfusion on fluorescein angiography and bilateral optic disk drusen. RESULT: A patient presented with blurring of vision in both eyes for last 6 months...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27926941/type-1-interferons-and-nk-cells-limit-murine-cytomegalovirus-escape-from-the-lymph-node-subcapsular-sinus
#17
Helen E Farrell, Kimberley Bruce, Clara Lawler, Rhonda D Cardin, Nicholas J Davis-Poynter, Philip G Stevenson
Cytomegaloviruses (CMVs) establish chronic, systemic infections. Peripheral infection spreads via lymph nodes, which are also a focus of host defence. Thus, this is a point at which systemic infection spread might be restricted. Subcapsular sinus macrophages (SSM) captured murine CMV (MCMV) from the afferent lymph and poorly supported its replication. Blocking the type I interferon (IFN-I) receptor (IFNAR) increased MCMV infection of SSM and of the fibroblastic reticular cells (FRC) lining the subcapsular sinus, and accelerated viral spread to the spleen...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27920876/bilateral-perirenal-space-fibromatosis-with-renal-infiltration-case-report-and-review-of-literature
#18
Avinash Sabale, Anil Pralhadan, Kalirajan Kalidos, Krishnankutty Ramachandran
Fibromatosis and/or desmoid tumors which constitute less than 1% of all neoplasms and 3.0% of all soft-tissue tumors are pathologically benign proliferations of the fibroblasts but are locally aggressive with infiltrative type of growth and tendency toward recurrence. Bilateral symmetrical perirenal involvement has been described in many conditions which can be renal, subcapsular, or perirenal in origin. However, bilateral perirenal fibromatosis as an isolated presentation was very uncommon. We report an exceptionally rare case of bilateral perirenal fibromatosis with renal infiltration...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27920849/subcapsular-hepatic-endometriosis-case-report-and-review-of-the-literature
#19
Ahmed Monier Sherif, Eman Rashid Musa, Rajendra Kedar, Liying Fu
Hepatic endometriosis is a very rare medical condition characterized by the implantation of ectopic endometrial tissue within the hepatic parenchyma. Preoperative diagnosis is difficult via cross-sectional imaging and histopathologic evaluation remains the gold standard for diagnosis. We report a case of hepatic endometrioma in a 44-year-old woman with history of endometriosis. The literature is reviewed, and magnetic resonance imaging findings together with differential diagnosis of hepatic endometriosis are highlighted...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27916565/the-association-of-exosomes-with-lymph-nodes
#20
REVIEW
Joshua L Hood
Cells produce extracellular nanovesicles known as exosomes that transport information between tissue microenvironments. Exosomes can engage and regulate the function of various immune cell types facilitating both normal and pathological processes. It follows that exosomes should also associate with lymph nodes containing immune cells. Herein, data derived from investigations that incorporate experiments pertaining to the trafficking of exosomes to lymph nodes is reviewed. Within lymph nodes, direct evidence demonstrates that exosomes associate with dendritic cells, subcapsular sinus macrophages, B lymphocytes and stromal cells...
December 2, 2016: Seminars in Cell & Developmental Biology
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