keyword
MENU ▼
Read by QxMD icon Read
search

Fatty acid omega 3

keyword
https://www.readbyqxmd.com/read/29035785/association-of-blood-polychlorinated-biphenyls-and-cholesterol-levels-among-canadian-inuit
#1
Kavita Singh, Hing Man Chan
BACKGROUND: It has generally been thought that Inuit populations have low risk of cardiovascular disease due to high consumption of omega-3 fatty acids found in traditional marine-based diets. However, results of recent surveys showed that Inuit populations are experiencing increasing rates of cardiovascular disease and related risk factors. OBJECTIVE: The purpose of this study was to investigate if blood polychlorinated biphenyls (PCBs) are associated with high cholesterol and related parameters in Canadian Inuit, known risk factors for cardiovascular disease...
October 13, 2017: Environmental Research
https://www.readbyqxmd.com/read/29035365/omega-3-fatty-acid-epoxides-are-autocrine-mediators-that-control-the-magnitude-of-ige-mediated-mast-cell-activation
#2
Yuta Shimanaka, Nozomu Kono, Yoshitaka Taketomi, Makoto Arita, Yoshimichi Okayama, Yuki Tanaka, Yasumasa Nishito, Tatsuki Mochizuki, Hiroyuki Kusuhara, Alexander Adibekian, Benjamin F Cravatt, Makoto Murakami, Hiroyuki Arai
Critical to the function of mast cells in immune responses including allergy is their production of lipid mediators, among which only omega-6 (ω-6) arachidonate-derived eicosanoids have been well characterized. Here, by employing comprehensive lipidomics, we identify omega-3 (ω-3) fatty acid epoxides as new mast cell-derived lipid mediators and show that they are produced by PAF-AH2, an oxidized-phospholipid-selective phospholipase A2. Genetic or pharmacological deletion of PAF-AH2 reduced the steady-state production of ω-3 epoxides, leading to attenuated mast cell activation and anaphylaxis following FcɛRI cross-linking...
October 9, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29034984/sensory-quality-and-fatty-acid-content-of-springbok-antidorcas-marsupialis-meat-influence-of-farm-location-and-gender
#3
Jeannine Neethling, Magdalena Muller, Marieta van der Rijst, Louwrens C Hoffman
BACKGROUND: Springbok are harvested for meat production irrespective of farm location or gender from which the meat is derived. This study investigated the influence of farm location (three farms containing different vegetation types) and gender on the sensory quality of springbok longissimus thoracis et lumborum muscle. The sensory profile (aroma, flavour and texture) was determined by descriptive sensory analysis, in addition to determining the physical meat quality, proximate and fatty acid composition...
October 16, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29034833/drug-therapy-for-abdominal-aortic-aneurysms-utilizing-omega-3-unsaturated-fatty-acids-and-their-derivatives
#4
Daisuke Akagi, Katsuyuki Hoshina, Toshiaki Watanabe, Micheal S Conte
Abdominal aortic aneurysms (AAA) are life-threatening because of the potential for rupture, resulting in death. The current standard treatment for AAA is surgery, comprising laparotomic graft replacement and endovascular repair. However, because surgery carries the risk of major complications and re-intervention, medical therapies are desirable because they may reduce the occurrence of enlargement and rupture. Recent research shows that the progression of AAA is related to inflammatory reactions, especially those in the NF-kB pathway...
October 13, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/29034731/effects-of-omega-3-fatty-acids-on-bone-turnover-markers-in-postmenopausal-women-systematic-review-and-meta-analysis
#5
D Shen, X Zhang, Z Li, H Bai, L Chen
AIM: There is conflicting evidence regarding the effects of omega-3 fatty acids on bone turnover markers in postmenopausal women. Thus, we systematically reviewed the efficacy of omega-3 fatty acids by conducting a meta-analysis of available randomized controlled trials. METHODS: PubMed, Embase, Cochrane Library and Scopus were searched in December 2016. The standardized mean difference (SMD) or weighted mean difference (WMD) and the corresponding 95% confidence intervals (CIs) were calculated using a fixed-effects model...
October 16, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29034183/alzheimer-disease-clues-from-traditional-and-complementary-medicine
#6
REVIEW
Edwin L Cooper, Melissa J Ma
Despite modern medicine's incredible innovation and resulting accumulation of valuable knowledge, many of the world's most problematic diseases such as Alzheimer Disease (AD) still lack effective cures and treatments. Western medicine has revealed many genetic, cellular, and molecular processes that characterize AD such as protein aggregation and inflammation. As the need for novel and effective treatments increases, researchers have turned towards traditional medicine as a resource. Modern, evidence based research examining traditional and complementary remedies for AD has generated promising results within the last decade...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29032859/the-effect-of-maternal-dha-supplementation-on-body-fat-mass-in-children-at-7-years-follow-up-of-the-domino-randomized-controlled-trial
#7
K Wood, E Mantzioris, B Lingwood, J Couper, M Makrides, R A Gibson, B S Muhlhausler
BACKGROUND: Animal studies have suggested that an increased supply of omega-3 long chain polyunsaturated fatty acids (LCPUFA), in particular docosahexaenoic acid (DHA), during the perinatal period can prevent later excess body fat mass. However, previous human studies have produced inconsistent findings, and few have assessed potential effects beyond 6 years of age. OBJECTIVE: To evaluate the effect of supplementing women in the second half of pregnancy with omega-3 LCPUFA, chiefly as DHA, on the percentage body fat of children at 7 years of age, as assessed by two methods: air displacement plethysmography (BOD POD) and bioelectrical impedance spectroscopy (BIS)...
September 22, 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29032079/omega-6-fatty-acid-biomarkers-and-incident-type-2-diabetes-pooled-analysis-of-individual-level-data-for-39%C3%A2-740-adults-from-20-prospective-cohort-studies
#8
Jason H Y Wu, Matti Marklund, Fumiaki Imamura, Nathan Tintle, Andres V Ardisson Korat, Janette de Goede, Xia Zhou, Wei-Sin Yang, Marcia C de Oliveira Otto, Janine Kröger, Waqas Qureshi, Jyrki K Virtanen, Julie K Bassett, Alexis C Frazier-Wood, Maria Lankinen, Rachel A Murphy, Kalina Rajaobelina, Liana C Del Gobbo, Nita G Forouhi, Robert Luben, Kay-Tee Khaw, Nick Wareham, Anya Kalsbeek, Jenna Veenstra, Juhua Luo, Frank B Hu, Hung-Ju Lin, David S Siscovick, Heiner Boeing, Tzu-An Chen, Brian Steffen, Lyn M Steffen, Allison Hodge, Gudny Eriksdottir, Albert V Smith, Vilmunder Gudnason, Tamara B Harris, Ingeborg A Brouwer, Claudine Berr, Catherine Helmer, Cecilia Samieri, Markku Laakso, Michael Y Tsai, Graham G Giles, Tarja Nurmi, Lynne Wagenknecht, Matthias B Schulze, Rozenn N Lemaitre, Kuo-Liong Chien, Sabita S Soedamah-Muthu, Johanna M Geleijnse, Qi Sun, William S Harris, Lars Lind, Johan Ärnlöv, Ulf Riserus, Renata Micha, Dariush Mozaffarian
BACKGROUND: The metabolic effects of omega-6 polyunsaturated fatty acids (PUFAs) remain contentious, and little evidence is available regarding their potential role in primary prevention of type 2 diabetes. We aimed to assess the associations of linoleic acid and arachidonic acid biomarkers with incident type 2 diabetes. METHODS: We did a pooled analysis of new, harmonised, individual-level analyses for the biomarkers linoleic acid and its metabolite arachidonic acid and incident type 2 diabetes...
October 11, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29031899/synapse-formation-in-the-brain-can-be-enhanced-by-co-administering-three-specific-nutrients
#9
Richard J Wurtman
The memory impairments of early Alzheimer's disease [AD] are thought to result from a deficiency in synapses within the hippocampus and related brain regions. This deficiency could result from an acceleration in synapse turnover - perhaps caused by an endogenous neurotoxin like A-beta oligomers - or from a decrease in the production of the synaptic membrane needed to form new synapses. An AD-associated decrease in synaptogenesis almost certainly does occur, inasmuch as major decreases are also observed in the numbers of hippocampal dendritic spines, the immediate cytologic precursor of glutamatergic synapses...
October 11, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29031403/the-role-of-specialized-pro-resolving-mediators-in-maternal-fetal-health
#10
REVIEW
E Elliott, C K Hanson, A L Anderson-Berry, T M Nordgren
Infants developing in a pro-inflammatory intrauterine environment have a significant risk for severe complications after birth. It has been shown that omega-3 fatty acids reduce inflammation, and also reduce early preterm births and decrease risk of infant admission to the neonatal intensive care unit. However, the mechanism for omega-3 fatty acids exerting these effects was previously unknown. Recent evidence has shown that downstream products of polyunsaturated fatty acids called specialized pro-resolving mediators may mediate inflammatory physiology, thus playing an important role in maternal-fetal health...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29031396/supplementing-dams-with-both-arachidonic-and-docosahexaenoic-acid-has-beneficial-effects-on-growth-and-immune-development
#11
K B Hadley, F Guimont-Desrochers, E Bailey-Hall, N Salem, K Yurko-Mauro, C J Field
Omega-3 long-chain polyunsaturated fatty acids (LCPUFAS) modulate immune cells in vitro and in vivo. This study investigated the effects of enriching the maternal diet with the n-6 and n-3 LCPUFAs, arachidonic (20:4n-6, 0.6%wt ARA) and docosahexaenoic acid (22:6n-3, 0.32%wt DHA), or 1:1 and 2:1 ratios (ARA: DHA) on total lipids in milk, total lipids, and immunophenotypes in plasma, lymph nodes, and spleen from isolated immune cells from 28d old pups. From day 15 of gestation to day 3 pp, Sprague-Dawley dams were fed a commercial chow...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29031393/cytokine-distribution-in-mothers-and-breastfed-children-after-omega-3-lcpufas-supplementation-during-the-last-trimester-of-pregnancy-and-the-lactation-period-a-randomized-controlled-trial
#12
Y Rodriguez-Santana, J J Ochoa, F Lara-Villoslada, N Kajarabille, P Saavedra-Santana, J A Hurtado, M Peña, J Diaz-Castro, I Sebastian-Garcia, E Machin-Martin, M Villanueva, O Ramirez-Garcia, L Peña-Quintana
OBJECTIVE: To determine whether maternal diet supplementation with omega-3 long chain polyunsaturated fatty acids (omega-3 LC-PUFAs) during the last trimester of pregnancy and the breastfeeding period influences the levels of inflammatory cytokines in mother and infants. MATERIAL AND METHOD: This registered, double-blind randomized study included 46 pregnant women, who were randomly allocated to either an experimental group receiving 400mL/day of a fish oil-enriched dairy drink [320mg docosahexaenoic acid (DHA) + 72mg eicoapentaenoic acid] (FO group, n = 24) or to a control group receiving 400mL/day of a non-supplemented dairy drink (CT group, n = 22), from week 28 of pregnancy until the fourth month of lactation...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29031392/effects-of-aspirin-in-combination-with-epa-and-dha-on-hdl-c-cholesterol-and-apoa1-exchange-in-individuals-with-type-2-diabetes-mellitus
#13
Robert C Block, Ashley Holub, Amir Abdolahi, Xin M Tu, Shaker A Mousa, Michael N Oda
BACKGROUND/SYNOPSIS: Low-dose aspirin is an effective drug for the prevention of cardiovascular disease (CVD) events but individuals with diabetes mellitus can be subject to 'aspirin resistance'. Thus, aspirin's effect in these individuals is controversial. Higher blood levels of seafood-derived omega-3 polyunsaturated fatty acids (ω3) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also have beneficial effects in reducing risk of CVD events but few studies have examined the interaction of plasma EPA and DHA with aspirin ingestion...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29031390/effects-of-postnatal-omega-3-fatty-acid-supplementation-on-offspring-pro-resolving-mediators-of-inflammation-at-6-months-and-5-years-of-age-a-double-blind-randomized-controlled-clinical-trial
#14
V H L See, E Mas, S L Prescott, L J Beilin, S Burrows, A E Barden, R C Huang, T A Mori
BACKGROUND: Resolution of inflammation is an active process involving specialised pro-resolving mediators (SPMs) generated from the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Omega-3 fatty acid supplementation during infancy may provide an intervention strategy to modify SPMs and reduce oxidative stress. This study evaluates the effect of omega-3 fatty acid supplementation in infancy on SPMs and F2-isoprostanes from 6 months to 5 years of age. METHODS: In a double-blind, placebo-controlled, parallel-group study design, 420 infants were randomized to a daily supplement of omega-3 fatty acids (280mg DHA and 110mg EPA) or olive oil (control), from birth to age 6 months...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29030414/longitudinal-associations-between-marine-omega-3-supplement-users-and-coronary-heart-disease-in-a-uk-population-based-cohort
#15
Marleen A H Lentjes, Ruth H Keogh, Ailsa A Welch, Angela A Mulligan, Robert N Luben, Nicholas J Wareham, Kay-Tee Khaw
OBJECTIVES: Assess the association between marine omega-3 polyunsaturated fatty acid (n-3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. DESIGN: Prospective cohort study, with three exposure measurements over 22 years. SETTING: Norfolk-based European Prospective Investigation into Cancer (EPIC-Norfolk, UK). PARTICIPANTS: 22 035 men and women from the general population, 39-79 years at recruitment...
October 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/29029330/the-association-between-omega-3-fatty-acid-biomarkers-and-inflammatory-arthritis-in-an-anti-citrullinated-protein-antibody-positive-population
#16
Ryan W Gan, Elizabeth A Bemis, M Kristen Demoruelle, Christopher C Striebich, Stacey Brake, Marie L Feser, LauraKay Moss, Michael Clare-Salzler, V Michael Holers, Kevin D Deane, Jill M Norris
Objectives: Higher circulating omega-3 fatty acids (n-3 FAs) are associated with a lower prevalence of anti-CCP antibodies and RF in subjects without RA. We examined whether, in anti-CCP+ subjects, n-3 FAs also play a role in development of inflammatory arthritis (IA). Methods: At Colorado-based health fairs from 2008 to 2014, participants without a previous diagnosis of RA who were anti-CCP3+ (n = 47) were recruited into a follow-up study; symptom assessments and joint examinations were conducted every 6 months for the determination of IA...
October 4, 2017: Rheumatology
https://www.readbyqxmd.com/read/29028650/fast-digestive-proteins-and-sarcopenia-of-aging
#17
Yves Boirie, Christelle Guillet
PURPOSE OF REVIEW: The speed of dietary protein digestion influences postprandial amino acid availability which is crucial for improving altered anabolic response of skeletal muscle one feature of sarcopenia during aging. RECENT FINDINGS: By analogy with carbohydrate and in reference to their absorption rate, dietary proteins can be classified as 'fast' or 'slow' proteins depending on matrix food structure and technological processes, which can influence amino acids availability and their subsequent metabolic actions...
October 11, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29027975/dietary-supplement-use-during-preconception-the-australian-longitudinal-study-on-women-s-health
#18
Elle McKenna, Alexis Hure, Anthony Perkins, Ellie Gresham
Worldwide, dietary supplement use among reproductive aged women is becoming increasingly common. The aim of this study was to investigate dietary supplement use among Australian women during preconception. Self-reported data were collected prospectively for the Australian Longitudinal Study on Women's Health (ALSWH). The sample included 485 women aged 31-36 years, with supplement data, classified as preconception when completing Survey 5 of the ALSWH in 2009. Frequency and contingency tables were calculated and Pearson's chi-square test for associations between demographic variables and supplementation status was performed...
October 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29027487/effect-of-tauroursodeoxycholic-acid-on-pufa-levels-and-inflammation-in-an-animal-and-cell-model-of-hepatic-endoplasmic-reticulum-stress
#19
M Aslan, E Kıraç, Ö Yılmaz, B Ünal, E K Konuk, F Özcan, H Tuzcu
The aim of this study was to evaluate hepatic polyunsaturated fatty acids (PUFAs) and inflammatory response in an animal and cell model of endoplasmic reticulum (ER) stress. Rats were divided into control, tunicamycin (TM)-treated, and TM + tauroursodeoxycholic acid (TUDCA)-treated groups. Hepatic ER stress was induced by TM and the ER stress inhibitor TUDCA was injected 30 min before induction of ER stress. Liver THLE-3 cells were treated with TM and TUDCA was administered in advance to decrease cytotoxic effects...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29024131/the-effect-of-dietary-supplementation-with-aurantiochytrium-limacinum-on-lactating-dairy-cows-in-terms-of-animal-health-productivity-and-milk-composition
#20
C A Moran, M Morlacchini, J D Keegan, G Fusconi
The aim of this study was to investigate the effect of dietary supplementation with the docosahexaenoic acid (DHA)-rich microalgae, Aurantiochytrium limacinum (AURA), on a variety of health and productivity parameters in lactating cows. Twenty-four cows were blocked by parity and number of days in milk and then randomly assigned to a control (CON; n = 12) group with no algal supplementation, or a treatment group (AURA; n = 12) provided with 100 g AURA cow(-1)  day(-1) or 16 g DHA cow(-1)  day(-1) ...
October 10, 2017: Journal of Animal Physiology and Animal Nutrition
keyword
keyword
66982
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"