keyword
MENU ▼
Read by QxMD icon Read
search

quality of life in systemic lupus erythematosus

keyword
https://www.readbyqxmd.com/read/28432050/prevalence-of-remission-and-its-effect-on-damage-and-quality-of-life-in-chinese-patients-with-systemic-lupus-erythematosus
#1
Chi Chiu Mok, Ling Yin Ho, Sau Mei Tse, Kar Li Chan
OBJECTIVES: To study the prevalence of remission and its effect on damage and quality of life (QOL) in Chinese patients with systemic lupus erythematosus (SLE). METHODS: Patients who fulfilled≥4 American College of Rheumatology criteria for SLE were identified. Their remission status at last clinic visits was determined by the European consensus criteria (complete/clinical remission ± immunosuppressive drugs). The increase in SLE damage index (SDI) in the preceding 5 years was compared between patients who were and were not in remission for ≥5 years...
April 21, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28425178/sleep-quality-clinical-and-psychological-manifestations-in-women-with-systemic-lupus-erythematosus
#2
Virginia Moraleda, Germán Prados, María P Martínez, Ana I Sánchez, José M Sabio, Elena Miró
AIM: Sleep problems are a common complaint in systemic lupus erythematosus (SLE) patients. We analyzed sleep quality with subjective and objective measures in a sample with SLE and its possible relationships with the main manifestations of the disease. METHODS: Twenty-one women with SLE and 20 healthy women participated in the study. All participants were evaluated with actigraphy for a week and they completed self-report instruments of sleep quality, quality of life, fatigue, anxiety, depression and perceived stress...
April 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28420059/neuropsychiatric-symptoms-in-systemic-lupus-erythematosus-impact-on-quality-of-life
#3
R C Monahan, L J J Beaart-van de Voorde, G M Steup-Beekman, C Magro-Checa, T W J Huizinga, J Hoekman, A A Kaptein
Objective Assess quality of life in patients with systemic lupus erythematosus (SLE) presenting with neuropsychiatric symptoms (neuropsychiatric SLE, NPSLE). Methods Quality of life was assessed using the Short-Form 36 item Health Survey (SF-36) in patients visiting the Leiden NPSLE clinic at baseline and at follow-up. SF-36 subscales and summary scores were calculated and compared with quality of life of the general Dutch population and patients with other chronic diseases. Results At baseline, quality of life was assessed in 248 SLE patients, of whom 98 had NPSLE (39...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28414781/voice-disorder-in-systemic-lupus-erythematosus
#4
Milena S F C de Macedo, Kauê M Costa, Manoel da Silva Filho
Systemic lupus erythematosus (SLE) is a chronic disease characterized by progressive tissue damage. In recent decades, novel treatments have greatly extended the life span of SLE patients. This creates a high demand for identifying the overarching symptoms associated with SLE and developing therapies that improve their life quality under chronic care. We hypothesized that SLE patients would present dysphonic symptoms. Given that voice disorders can reduce life quality, identifying a potential SLE-related dysphonia could be relevant for the appraisal and management of this disease...
2017: PloS One
https://www.readbyqxmd.com/read/28411133/clinical-significance-of-fibromyalgia-syndrome-in-different-rheumatic-diseases-relation-to-disease-activity-and-quality-of-life
#5
Sarah El-Rabbat M, Nermeen K Mahmoud, Tamer A Gheita
OBJECTIVE: To describe the frequencies of fibromyalgia syndrome (FMS) in various rheumatic diseases; rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and Behçets disease (BD) patients and to study the relation to clinical manifestations and quality of life (QoL). PATIENTS AND METHODS: 160 patients (50 RA, 50 SLE, 30 SSc and 30 BD) and matched corresponding healthy controls were included. Disease activity was assessed using disease activity score in 28 joints (DAS28) for RA, SLE Disease Activity index (SLEDAI), modified Rodnan skin score for SSc and BD Current Activity Form (BDCAF)...
April 11, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28394225/outcomes-of-neuropsychiatric-events-in-systemic-lupus-erythematosus-based-on-clinical-phenotypes-prospective-data-from-the-leiden-np-sle-cohort
#6
C Magro-Checa, L J J Beaart-van de Voorde, H A M Middelkoop, M L Dane, N J van der Wee, M A van Buchem, T W J Huizinga, G M Steup-Beekman
Objective The objective of this study was to assess whether clinical and patient's reported outcomes are associated with a different pathophysiological origin of neuropsychiatric events presenting in systemic lupus erythematosus. Methods A total of 232 neuropsychiatric events presenting in 131 systemic lupus erythematosus patients were included. Neuropsychiatric systemic lupus erythematosus diagnosis was established per event by multidisciplinary evaluation. All neuropsychiatric events were divided according to a suspected underlying pathophysiological process into one of the following: non-neuropsychiatric systemic lupus erythematosus related, inflammatory and ischaemic neuropsychiatric systemic lupus erythematosus...
April 2017: Lupus
https://www.readbyqxmd.com/read/28387089/-seizures-in-patients-with-systemic-lupus-erythematosus
#7
A Rezgui, N Ghannouchi, A Gabbouj, J Anoun, M Karmani, A Mzabi, F Ben Fredj, F Bahri, Ch Laouani
Seizures are one of the most serious neuropsychiatric manifestations of systemic lupus erythematous (SLE). This descriptive and retrospective study aims at describing clinical and paraclinical features and therapeutic approach of seizures in patients with SLE. The characteristics of the seizure group was compared to those of a control group (patients with LES who had not presented seizures). A total of 177 patients were included in these analyses. Among them, 14 (8 %) developed seizures before, at or after the SLE diagnosis...
February 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28385125/multicenter-study-to-assess-presenteeism-in-systemic-lupus-erythematosus-and-its-relationship-with-clinical-and-sociodemographic-features
#8
M A Cosatti, S Muñoz, P Alba, C A Helling, S Roverano, J Sarano, S Malm-Green, M Danielsen, D Medina Bornachera, A Alvarez, A Eimon, G Pendón, M Mayer, J Marin, C Catoggio, C N Pisoni
Objective The aim of this study was to measure presenteeism (productivity impairment while the patient is at work) and the related risk factors in patients with systemic lupus erythematosus (SLE) from Argentina. Methods A total of 130 consecutive (1997 American College of Rheumatology (ACR) criteria) working patients with SLE were assessed using a standardized data collection form. Sociodemographic, disease and work-related variables were collected. The Work Productivity and Activity Impairment (WPAI) questionnaire was performed...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28367173/cognitive-dysfunction-in-patients-with-systemic-lupus-erythematosus
#9
Bilal Azeem Butt, Sumaira Farman, Saira Elaine Anwer Khan, Muhammad Ahmed Saeed, Nighat Mir Ahmad
OBJECTIVE: To determine the frequency of cognitive dysfunction in patients with Systemic Lupus Erythematosus in a Pakistani population, presenting at a tertiary care Rheumatology setting. METHODS: This cross-sectional study was conducted at the Division of Rheumatology, Fatima Memorial Hospital, Lahore, from March to June 2016. A total of 43 consecutive patients, who fulfilled the 2012 SLICC (Systemic Lupus International Collaborating Clinics) classification criteria for Systemic Lupus Erythematosus (SLE), were enrolled...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28357813/rate-of-adverse-effects-of-medium-to-high-dose-glucocorticoid-therapy-in-systemic-lupus-erythematosus-a-systematic-review-of%C3%A2-randomized-control-trials
#10
REVIEW
Savino Sciascia, Elisa Mompean, Massimo Radin, Dario Roccatello, Maria J Cuadrado
BACKGROUND AND OBJECTIVES: The efficacy of glucocorticoids (GCs) in treating systemic lupus erythematosus (SLE) is beyond doubt. However, GCs-related adverse effects (AEs) are multiple and serious. Despite the current available evidence suggesting to reduce daily doses of prednisone <7.5 mg/day, or even to withdraw it, in the real-life practice, it is not uncommon to see patients receiving medium doses (up to 30 mg/day prednisone or equivalent) or high doses (≥30 mg/day). METHODS: We systematically reviewed the literature with a priori strategy, to assess the rate of AEs related to medium or high doses of GCs in patients with SLE, analyzing randomized control trials with at least one of the treatment groups including GCs alone at medium or high doses...
March 29, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28351341/impact-of-disease-activity-on-health-related-quality-of-life-in-systemic-lupus-erythematosus-a-cross-sectional-analysis-of-the-swiss-systemic-lupus-erythematosus-cohort-study-sscs
#11
Benjamin Chaigne, Carlo Chizzolini, Thomas Perneger, Marten Trendelenburg, Uyen Huynh-Do, Eric Dayer, Thomas Stoll, Johannes von Kempis, Camillo Ribi
BACKGROUND: To assess the impact of disease activity on health-related quality of life (HRQoL) in systemic lupus erythematosus (SLE). METHODS: Cross-sectional study of patients included in the Swiss SLE Cohort Study between April 2007 and June 2014. HRQoL outcomes were based on the Medical Outcome Study Short Form 36 (SF-36). Disease activity was assessed by the SLE Disease Activity Index score with the Safety of Estrogens in SLE National Assessment modification (SELENA-SLEDAI) and by the physican's global assessment (PGA)...
March 28, 2017: BMC Immunology
https://www.readbyqxmd.com/read/28320433/association-of-the-lupus-low-disease-activity-state-lldas-with-health-related-quality-of-life-in-a-multinational-prospective-study
#12
Vera Golder, Rangi Kandane-Rathnayake, Alberta Yik-Bun Hoi, Molla Huq, Worawit Louthrenoo, Yuan An, Zhan Guo Li, Shue Fen Luo, Sargunan Sockalingam, Chak Sing Lau, Mo Yin Mok, Aisha Lateef, Kate Franklyn, Susan Morton, Sandra Teresa V Navarra, Leonid Zamora, Yeong-Jian Wu, Laniyati Hamijoyo, Madelynn Chan, Sean O'Neill, Fiona Goldblatt, Mandana Nikpour, Eric Francis Morand
BACKGROUND: Systemic lupus erythematosus (SLE) is associated with significant impairment of health-related quality of life (HR-QoL). Recently, meeting a definition of a lupus low disease activity state (LLDAS), analogous to low disease activity in rheumatoid arthritis, was preliminarily validated as associated with protection from damage accrual. The LLDAS definition has not been previously evaluated for association with patient-reported outcomes. The objective of this study was to determine whether LLDAS is associated with better HR-QoL, and examine predictors of HR-QoL, in a large multiethnic, multinational cohort of patients with SLE...
March 20, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28320078/comparison-of-the-sensitivity-to-change-of-the-36-item-short-form-health-survey-and-the-lupusqol-using-various-definitions-of-minimal-clinically-important-differences-in-patients-with-active-systemic-lupus-erythematosus
#13
Stephanie G Nantes, Vibeke Strand, Jiandong Su, Zahi Touma
OBJECTIVES: Medical Outcomes Study Short-Form 36 (SF-36) and LupusQoL are Health-Related Quality-of-Life (HRQoL) questionnaires used in systemic lupus erythematosus (SLE). We determined the hypothesis testing construct validity of SF-36 and LupusQoL against disease activity in patients with active SLE and 2) compared the sensitivity to change of SF-36 and LupusQoL domains according to different definitions of Minimal Clinically Important Differences (MCID) for improvement and worsening in the current cohort...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28294088/an-update-on-diet-and-nutritional-factors-in-systemic-lupus-erythematosus-management
#14
Marina Aparicio-Soto, Marina Sánchez-Hidalgo, Catalina Alarcón-de-la-Lastra
Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease characterised by multiple organ involvement and a large number of complications. SLE management remains complicated owing to the biological heterogeneity between patients and the lack of safe and specific targeted therapies. There is evidence that dietary factors can contribute to the geoepidemiology of autoimmune diseases such as SLE. Thus, diet therapy could be a promising approach in SLE owing to both its potential prophylactic effects, without the side effects of classical pharmacology, and its contribution to reducing co-morbidities and improving quality of life in patients with SLE...
March 15, 2017: Nutrition Research Reviews
https://www.readbyqxmd.com/read/28292254/impact-of-joint-involvement-on-patients-reported-outcomes-in-systemic-lupus-erythematosus
#15
Chiara Tani, Linda Carli, Andrea Delle Sedie, Lucrezia Riente, Sabrina Vagnani, Rosaria Talarico, Alessandra Della Rossa, Chiara Baldini, Stefano Bombardieri, Marta Mosca
OBJECTIVE: Joint involvement is common among patients with systemic lupus erythematosus (SLE). Aim of this work was to evaluate the correlation between the presence of joint involvement and patient-reported pain, perception of disease activity, general health and quality of life. METHODS: Fifty consecutive SLE patients were enrolled in the study. All patients underwent a complete clinical evaluation including a 44 joint count, in addition an ultrasound evaluation of joint involvement of hands and wrists was performed...
March 14, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28285445/differential-impact-of-systemic-lupus-erythematosus-and-rheumatoid-arthritis-on-health-related-quality-of-life
#16
Benjamin Chaigne, Axel Finckh, Deshire Alpizar-Rodriguez, Delphine Courvoisier, Camillo Ribi, Carlo Chizzolini
PURPOSE: This study examined and compared health-related quality of life (QoL) in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). METHODS: We included patients from two multicentric cohorts, the Swiss SLE cohort study (SSCS) and the Swiss Clinical Quality Management Program for RA (SCQM-RA). Patients were matched by age, sex and disease duration using the propensity score. Disease activity was assessed by SELENA-SLEDAI in SLE and by DAS-28 in RA...
March 11, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28114336/factors-associated-with-health-related-quality-of-life-in-mexican-lupus-patients-using-the-lupusqol
#17
I Etchegaray-Morales, S Méndez-Martínez, C Jiménez-Hernández, C Mendoza-Pinto, N E Alonso-García, A Montiel-Jarquín, A López-Colombo, A García-Villaseñor, M H Cardiel, M García-Carrasco
INTRODUCTION: Health-related quality of life (HRQOL) is affected by numerous clinical variables, including disease activity, damage, fibromyalgia, depression and anxiety. However, these associations have not yet been described in Mexican patients with systemic lupus erythematosus (SLE). OBJECTIVE: To evaluate the relationship between disease activity, damage, depression and fibromyalgia and HRQOL measured by the LupusQoL-instrument in Mexican patients with SLE. METHODS: A cross-sectional study was conducted in women fulfilling the 1997 ACR classification criteria for SLE...
2017: PloS One
https://www.readbyqxmd.com/read/28089979/quality-of-care-for-systemic-lupus-erythematosus-mind-the-knowledge-gap
#18
Vera Golder, Eric F Morand, Alberta Y Hoi
Systemic lupus erythematosus (SLE) is a prototypical chronic multiorgan autoimmune disorder that can lead to significant burden of disease and loss of life expectancy. The disease burden is the result of a complex interplay between genetic, biologic, socioeconomic, and health system variables affecting the individual. Recent advances in biological understanding of SLE are yet to translate to transformative therapies, and genetic and socioeconomic variables are not readily amenable to intervention. In contrast, healthcare quality, a variable readily amenable to change, has been inadequately addressed in SLE, despite evidence in other chronic diseases that quality of care is strongly associated with patient outcomes...
January 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28059025/a-multi-group-confirmatory-factor-analyses-of-the-lupuspro-between-southern-california-and-filipino-samples-of-patients-with-systemic-lupus-erythematosus
#19
D R Azizoddin, R Olmstead, C Cost, M Jolly, J Ayeroff, G Racaza, L A Sumner, S Ormseth, M Weisman, P M Nicassio
Introduction Systemic lupus erythematosus (SLE) leads to a range of biopsychosocial health outcomes through an unpredictable and complex disease path. The LupusPRO is a comprehensive, self-report measure developed specifically for populations with SLE, which assesses both health-related quality of life and non-health related quality of life. Given its increasingly widespread use, additional research is needed to evaluate the psychometric integrity of the LupusPRO across diverse populations. The objectives of this study were to evaluate the performance of the LupusPRO in two divergent patient samples and the model fit between both samples...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/27992002/neuropsychiatric-lupus-in-clinical-practice
#20
Helena Alessi, Lívia Almeida Dutra, Pedro Braga, José Luiz Pedroso, Fabio F Toso, Cristiane Kayser, Orlando G P Barsottini
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations...
December 2016: Arquivos de Neuro-psiquiatria
keyword
keyword
66980
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"