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Cryobiopsy

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https://www.readbyqxmd.com/read/28326178/introduction-of-cryobiopsies-in-the-diagnostics-of-interstitial-lung-diseases-experiences-in-a-referral-center
#1
Sissel Kronborg-White, Birgitte Folkersen, Torben Riis Rasmussen, Nina Voldby, Line Bille Madsen, Finn Rasmussen, Venerino Poletti, Elisabeth Bendstrup
Introduction: Transbronchial cryobiopsies (cTBB) has emerged as a new method for obtaining lung tissue biopsies in the diagnosis of interstitial lung diseases (ILDs). Until now, it has been used in a few highly specialized interventional centers and has shown promising results in obtaining a definite diagnosis of ILDs. Method: All patients undergoing a cTBB between November 2015 and June 2016 were included in this case series study. Data on patient demographics, high-resolution computed tomography patterns, size and number of biopsies, histology patterns, the contribution to a confident diagnosis and complications were registered...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28323739/bronchoscopic-transbronchial-cryobiopsy-diagnosis-of-recurrent-diffuse-large-b-cell-lymphoma-in-the-lung-a-promising-new-tool
#2
Elaine Yap, Irene Low
No abstract text is available yet for this article.
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28323734/radial-probe-ultrasound-guided-cryobiopsy
#3
Ilya G Berim, Ali I Saeed, Ahmed Awab, Adam Highley, Agnes Colanta, Fawad Chaudry
Fluoroscopy-guided transbronchial forceps biopsy has a low diagnostic yield in patients with radiographic suspicion of interstitial lung disease. Cryobiopsy has a higher diagnostic yield likely due to preserved lung architecture and larger biopsies; however, there is an increased risk of major airway bleeding and pneumothorax. Simultaneous use of endobronchial balloon blocker allows for containment of bleeding after cryobiopsy to the affected lobe. In the current article we describe use of radial ultrasound in identification of a target lung parenchyma without a major blood vessel adjacent to distal bronchi...
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28323726/a-single-us-center-experience-of-transbronchial-lung-cryobiopsy-for-diagnosing-interstitial-lung-disease-with-a-2-scope-technique
#4
Thitiwat Sriprasart, Alejandro Aragaki, Robert Baughman, Kathryn Wikenheiser-Brokamp, Gaurav Khanna, Daniel Tanase, Michelle Kirschner, Sadia Benzaquen
BACKGROUND: Transbronchial lung cryobiopsy (TBLC) has been used to establish the diagnosis of interstitial lung disease (ILD) in recent years. The technique and diagnostic yield vary among institutions. We report a new 2-scope technique and the results of TBLC in our institution. METHODS: This is a retrospective chart review of patients who underwent TBLC for evaluation of ILD. Bronchoscopy with TBLC was performed by a board-certified interventional pulmonologist with a 2-scope technique under general anesthesia...
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28261482/pneumonic-type-mucinous-lung-adenocarcinoma-diagnosed-by-transbronchial-cryobiopsy
#5
Rick Balestra, Akilan Selvaraju, Sadia Benzaquen, Dani S Zander
Primary lung adenocarcinoma with lepidic growth can mimic diffuse pulmonary parenchymal processes like infectious pneumonia or idiopathic inflammatory pneumonitis. We report a case of subacute pneumonitis refractory to antibiotic therapy and empirical corticosteroids, proven to be diffuse mucinous adenocarcinoma with lepidic growth on transbronchial cryobiopsy.
May 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28245447/transbronchial-lung-cryobiopsy-in-diffuse-parenchymal-lung-disease-comparison-between-biopsy-from-1-segment-and-biopsy-from-2-segments-diagnostic-yield-and-complications
#6
Claudia Ravaglia, Athol U Wells, Sara Tomassetti, Alessandra Dubini, Alberto Cavazza, Sara Piciucchi, Nicola Sverzellati, Carlo Gurioli, Christian Gurioli, Ulrich Costabel, Paola Tantalocco, Jay H Ryu, Marco Chilosi, Venerino Poletti
BACKGROUND: Transbronchial lung cryobiopsy is an innovative method of obtaining samples from the parenchyma of patients with diffuse parenchymal lung diseases. However, the technique is not yet standardized, and uncertainty exists about the optimal protocol, including the number of samples, the biopsy size, and the choice of the biopsy site. OBJECTIVES: To compare the diagnostic yield and complications of cryobiopsy with different strategies adopted to sample lung tissue (number of samples, biopsy site, and sample size)...
March 1, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28231021/high-complication-rate-after-introduction-of-transbronchial-cryobiopsy-into-clinical-practice-at-an-academic-medical-center
#7
David M DiBardino, Andrew R Haas, Anthony R Lanfranco, Leslie A Litzky, Daniel Sterman, Jamie L Bessich
RATIONALE: Transbronchial cryobiopsy is an emerging technique for obtaining biopsies of lung parenchyma. Despite limited evidence of safety and efficacy in direct comparison to other available biopsy procedures, pulmonologists are integrating this technique into clinical practice with the hope of avoiding the risks of surgical lung biopsy. OBJECTIVES: To report the rate of severe complications and diagnostic outcomes immediately after introduction of transbronchial cryobiopsy into the clinical practice of a single-center, high-volume, interventional pulmonary group at a large academic medical center in the United States...
February 23, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28195964/bronchoscopic-transbronchial-cryobiopsy-diagnosis-of-recurrent-diffuse-large-b-cell-lymphoma-in-the-lung-a-promising-new-tool
#8
Elaine Yap, Irene Low
No abstract text is available yet for this article.
February 10, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28169912/radial-probe-ultrasound-guided-cryobiopsy
#9
Ilya G Berim, Ali I Saeed, Ahmed Awab, Adam Highley, Agnes Colanta, Fawad Chaudry
Fluoroscopy-guided transbronchial forceps biopsy has a low diagnostic yield in patients with radiographic suspicion of interstitial lung disease. Cryobiopsy has a higher diagnostic yield likely due to preserved lung architecture and larger biopsies; however, there is an increased risk of major airway bleeding and pneumothorax. Simultaneous use of endobronchial balloon blocker allows for containment of bleeding after cryobiopsy to the affected lobe. In the current article we describe use of radial ultrasound in identification of a target lung parenchyma without a major blood vessel adjacent to distal bronchi...
February 6, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28149581/recent-advances-in-diagnostic-bronchoscopy
#10
REVIEW
Philip G Ong, Labib G Debiane, Roberto F Casal
The field of diagnostic bronchoscopy has been revolutionized in the last decade primarily with the advent of endobronchial ultrasound (EBUS) but also with the addition of multiple different techniques for "guided-bronchoscopy". These advances have had a substantial impact in the management of lung cancer with bronchoscopy now providing both diagnosis and mediastinal staging in a single procedure. EBUS has, in fact, become the first choice for staging of the mediastinum over cervical mediastinoscopy (CM). Although EBUS is now a well-established technique, there are continuous efforts from the scientific community to improve its diagnostic performance, and these will be reviewed in this manuscript...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28144060/radial-endobronchial-ultrasound-for-the-diagnosis-of-bronchoscopically-invisible-lesions-first-case-series-from-india
#11
Kedar Ravi Hibare, Rajiv Goyal, Chetan Nemani, Rao Avinash, Bajpai Ram, Batra Ullas
BACKGROUND: A peripheral, bronchoscopically invisible pulmonary lesion is a diagnostic challenge. Transthoracic needle aspiration has long been the investigation of choice but runs the risk of pneumothorax (up to 44%). Newer technologies like radial endobronchial ultrasound (R-EBUS) offer a safer approach. We present our results of R-EBUS in the diagnosis of bronchoscopically invisible lesions. This is the first large case series from India. AIMS: (1) To determine the yield of R-EBUS for the diagnosis of bronchoscopically invisible lesions...
January 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27847813/jet-ventilation-during-rigid-bronchoscopy-in-adults-a-focused-review
#12
REVIEW
Laurie Putz, Alain Mayné, Anne-Sophie Dincq
The indications for rigid bronchoscopy for interventional pulmonology have increased and include stent placements and transbronchial cryobiopsy procedures. The shared airway between anesthesiologist and pulmonologist and the open airway system, requiring specific ventilation techniques such as jet ventilation, need a good understanding of the procedure to reduce potentially harmful complications. Appropriate adjustment of the ventilator settings including pause pressure and peak inspiratory pressure reduces the risk of barotrauma...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27789161/-idiopathic-interstitial-pneumonias-in-2016
#13
REVIEW
M-P Debray, R Borie, C Danel, A Khalil, M Majlath, B Crestani
Idiopathic interstitial pneumonias comprise 8 clinicopathological entities, most of them with a chronic course and various prognosis. Idiopathic pulmonary fibrosis is the most frequent and most severe of these. Computed tomography has an important role for its diagnosis. It can identify the corresponding pathological pattern of usual interstitial pneumonia in about 50 percent of cases. It can suggest differential diagnosis in other cases, most frequently fibrosing nonspecific interstitial pneumonia and chronic hypersensitivity pneumonitis...
February 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/27660154/transbronchial-cryobiopsy-in-diffuse-parenchymal-lung-disease-retrospective-analysis-of-74-cases
#14
Kamonpun Ussavarungsi, Ryan M Kern, Anja C Roden, Jay H Ryu, Eric S Edell
BACKGROUND: Diagnostic evaluation of patients with diffuse parenchymal lung disease (DPLD) is best achieved by a multidisciplinary team correlating clinical, radiological, and pathologic features. Surgical lung biopsy remains the gold standard for histopathologic diagnosis of idiopathic interstitial pneumonias. Emerging data suggest an increasing role for transbronchial cryobiopsy (TBC) in DPLD evaluation. We describe our experience with TBC in patients with DPLD. METHODS: We retrospectively reviewed medical records of patients with radiographic features of DPLD who underwent TBC at Mayo Clinic in Rochester, Minnesota from June 2013 to September 2015...
February 2017: Chest
https://www.readbyqxmd.com/read/27588334/transbronchial-cryobiopsy-in-diffuse-lung-disease-update-for-the-pathologist
#15
Thomas V Colby, Sara Tomassetti, Alberto Cavazza, Alessandra Dubini, Venerino Poletti
Context .- Transbronchial cryobiopsy has recently been proposed as an alternative to surgical biopsy in the diagnosis of diffuse lung disease. Objective .- To familiarize pathologists with transbronchial cryobiopsy, including what it is, how it is performed, how it compares to other techniques of lung biopsy in diffuse lung disease, what are the technical issues relating to it, what the complications are, how cryobiopsies should be interpreted, and the clinical usefulness of cryobiopsy. Data Sources .- All the available literature on cryobiopsy in diffuse lung disease through May 2016, primarily in the last 5 years, was reviewed, and some unpublished data known to the authors were included...
September 2, 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27581618/use-of-cryobiopsy-during-pleuroscopy-for-diagnosis-of-sarcomatoid-malignant-mesothelioma
#16
Hiang-Ping Chan, Mei-Fong Liew, Ju-Ee Seet, Pyng Lee
No abstract text is available yet for this article.
August 31, 2016: Thorax
https://www.readbyqxmd.com/read/27521584/how-we-will-diagnose-ipf-in-the-future
#17
REVIEW
L Richeldi
The recent approval of two safe and effective treatments for patients with idiopathic pulmonary fibrosis (IPF) had as a direct consequence the absolute need for an accurate and early diagnosis. The standard approach to IPF diagnosis has proven to be effective and emphasized the importance of clinical and laboratory evaluations to exclude known causes of pulmonary fibrosis. At the same time, chest high-resolution computed tomography (HRCT) has proven to be the crucial initial diagnostic test, by identifying those patients who should undergo surgical lung biopsy to secure a confident diagnosis and an adequate treatment...
September 2016: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/27521581/use-of-transbronchial-cryobiopsy-in-the-diagnosis-of-interstitial-lung-disease-a-systematic-review-and-cost-analysis
#18
C Sharp, M McCabe, H Adamali, A R Medford
BACKGROUND: Histological diagnosis by surgical lung biopsy for interstitial lung disease (ILD) is currently limited. Transbronchial cryobiopsy via flexible bronchoscope may this for more patients. The relative costs, diagnostic yields and safety of this approach and more traditional approaches have not been determined. OBJECTIVES: To perform a systematic review and meta-analysis of transbronchial cryobiopsy, forceps transbronchial biopsy and video assisted (VATS) surgical lung biopsy assessing their relative diagnostic yields and safety...
August 13, 2016: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/27466899/diagnostic-yield-and-complications-of-transbronchial-lung-cryobiopsy-for-interstitial-lung-disease-a-systematic-review-and-metaanalysis
#19
Kerri A Johannson, Veronica S Marcoux, Paul E Ronksley, Christopher J Ryerson
RATIONALE: The diagnostic usefulness and safety of transbronchial lung cryobiopsy for the evaluation of interstitial lung disease remain unclear. OBJECTIVES: This systematic review and metaanalysis aims to establish the diagnostic accuracy and yield of transbronchial cryobiopsy for interstitial lung diseases. METHODS: We searched MedLine, EMBASE, Cochrane Central Register of Controlled Trials, and conference proceedings to identify studies assessing the diagnostic accuracy (compared with surgical biopsy) or yield of transbronchial lung cryobiopsy for interstitial lung disease (from database inception to January 2016)...
October 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27441784/transbronchial-lung-cryobiopsy-for-interstitial-lung-disease-diagnosis-a-perspective-from-members-of-the-pulmonary-pathology-society
#20
Kirtee Raparia, Dara L Aisner, Timothy Craig Allen, Mary Beth Beasley, Alain Borczuk, Philip T Cagle, Vera Capelozzi, Sanja Dacic, Lida P Hariri, Keith M Kerr, Sylvie Lantuejoul, Mari Mino-Kenudson, Natasha Rekhtman, Anja C Roden, Sinchita Roy-Chowdhuri, Lynette Sholl, Maxwell L Smith, Eric Thunnissen, Ming Sound Tsao, Yasushi Yatabe
Transbronchial lung cryobiopsy involves using a cryoprobe rather than forceps to obtain a bronchoscopic biopsy. Recent studies have shown that transbronchial cryobiopsy provides a larger specimen than conventional transbronchial forceps biopsy, and that the interobserver agreement in the interpretation of cryobiopsy specimens is comparable to that of a surgical lung biopsy. This is encouraging, and transbronchial lung cryobiopsy clearly has a role in the workup and diagnosis of interstitial lung diseases. However, very few patients who have been studied underwent both transbronchial lung cryobiopsy and surgical lung biopsy, and the available data suggest that the diagnostic accuracy of cryobiopsy may not be similar to that of surgical lung biopsy...
July 21, 2016: Archives of Pathology & Laboratory Medicine
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