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type 2 diabetes, surgery

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https://www.readbyqxmd.com/read/28921837/coronary-artery-bypass-grafting-versus-percutaneous-coronary-intervention-in-patients-with-non-insulin-treated-type-2-diabetes-mellitus-a-meta-analysis-of-randomized-controlled-trials
#1
Yushu Wang, Meiqin Wen, Junteng Zhou, Yucheng Chen, Qing Zhang
INTRODUCTION: The outcomes and prognosis of revascularization by either coronary artery bypass grafting (CABG) surgery or percutaneous coronary intervention (PCI) in patients with non-insulin treated type 2 diabetes mellitus (NITDM) have not yet been well established. METHODS: Randomized controlled trials (RCTs) were identified by searching Pubmed, EMBASE and Cochrane library from inception until May 2016. Heterogeneity was evaluated and the pooled hazard ratio (HR) was calculated using a fixed-effect model...
September 15, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28916564/modulation-of-the-gut-microbiome-a-systematic-review-of-the-effect-of-bariatric-surgery
#2
Yan Guo, Zhi-Ping Huang, Chao-Qian Liu, Lin Qi, Yuan Sheng, Da-Jin Zou
OBJECTIVE: Bariatric surgery is recommended for patients with obesity and type 2 diabetes. Recent evidence suggested a strong connection between gut microbiota and bariatric surgery. DESIGN: Systematic review. METHODS: The PubMed and OVID Embase were used and articles concerning bariatric surgery and gut microbiota were screened. The main outcome measures were alterations of gut microbiota after bariatric surgery and correlations between gut microbiota and host metabolism...
September 15, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28914701/elevated-postvoid-residual-urine-volume-identifying-risk-factors-and-predicting-resolution-in-women-with-pelvic-organ-prolapse
#3
Amanda Ulrich, Patricia Davis, Paul Tulikangas, David M OʼSullivan, Katie Propst
OBJECTIVES: This study aims to identify risk factors for elevated preoperative postvoid residual (PVR) and persistently elevated postoperative PVR and to evaluate the resolution rate of elevated PVR urine volume in patients undergoing reconstructive surgery for pelvic organ prolapse (POP). METHODS: This was a retrospective cohort study comparing 50 women with elevated preoperative PVR (≥100 mL) and 50 women with normal PVR (<100 mL). Preoperative demographic, physical examination, urodynamic data, type of surgery performed, and postoperative trial of void data were collected...
September 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28914527/locally-induced-adipose-tissue-browning-by-microneedle-patch-for-obesity-treatment
#4
Yuqi Zhang, Qiongming Liu, Jicheng Yu, Shuangjiang Yu, Jinqiang Wang, Li Qiang, Zhen Gu
Obesity is one of the most serious public health problems in the 21st century that may lead to many comorbidities such as type-2 diabetes, cardiovascular diseases, and cancer. Current treatments toward obesity including diet, physical exercise, pharmacological therapy, as well as surgeries are always associated with low effectiveness or undesired systematical side effects. In order to enhance treatment efficiency with minimized side effects, we developed a transcutaneous browning agent patch to locally induce adipose tissue transformation...
September 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28911976/gestational-diabetes-and-the-long-term-risk-of-cataract-surgery-a-longitudinal-cohort-study
#5
Nathalie Auger, Tina Tang, Jessica Healy-Profitós, Gilles Paradis
AIMS: We assessed the long-term risk of cataract following a pregnancy complicated by gestational diabetes. METHODS: We carried out a longitudinal cohort study of 1,108,541 women who delivered infants between 1989-2013 in Quebec, Canada, with follow-up extending up to 25years later. The cohort included 71,862 women with gestational diabetes and 5247 with cataracts. We used Cox regression models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association of gestational diabetes with subsequent risk of cataract, adjusted for age, parity, socioeconomic status, time period, comorbidity, and type 2 diabetes...
August 9, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28902601/impact-of-diabetes-on-perioperative-complications-in-patients-undergoing-elective-total-shoulder-arthroplasty
#6
Siddharth Mahure, Brent Mollon, Mary Quien, Raj Karia, Joseph Zuckerman, Young Kwon
INTRODUCTION: Diabetes has been associated with negative outcomes following orthopaedic surgery. While previous studies have reported on diabetes-associated complications in shoulder arthroplasty, those cohorts were heterogeneous in terms of patient population, nature of elective surgery, and arthroplasty type. Given that the number of elective total shoulder arthroplasties (TSAs) performed has grown substantially in volume and is predicted to rise even further, it is important to recognize the role that diabetes may play in developing in-hospital complications within a more homogenous sample of patients undergoing elective TSA...
May 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28894292/partitioning-of-adipose-lipid-metabolism-by-altered-expression-and-function-of-ppar-isoforms-after-bariatric-surgery
#7
C Jahansouz, H Xu, A V Hertzel, S Kizy, K A Steen, R Foncea, F J Serrot, N Kvalheim, G Luthra, K Ewing, D B Leslie, S Ikramuddin, D A Bernlohr
BACKGROUND: Bariatric surgery remains the most effective treatment for reducing adiposity and eliminating type 2 diabetes; however, the mechanism(s) responsible have remained elusive. Peroxisome proliferator-activated receptors (PPAR) encompass a family of nuclear hormone receptors that upon activation exert control of lipid metabolism, glucose regulation and inflammation. Their role in adipose tissue following bariatric surgery remains undefined. MATERIALS AND METHODS: Subcutaneous adipose tissue biopsies and serum were obtained and evaluated from time of surgery and on postoperative day 7 in patients randomized to Roux-en-Y gastric bypass (n=13) or matched caloric restriction (n=14), as well as patients undergoing vertical sleeve gastrectomy (n=33)...
August 14, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28894238/prevalence-and-causes-of-low-vision-and-blindness-in-a-chinese-population-with-type-2-diabetes-the-dongguan-eye-study
#8
Ying Cui, Liang Zhang, Min Zhang, Xiaohong Yang, Lixin Zhang, Jian Kuang, Guanrong Zhang, Qingyang Liu, Haike Guo, Qianli Meng
To assess the prevalence and causes of low vision and blindness in type 2 diabetes patients, a population-based cross-sectional study including 8952 rural-dwelling residents aged 40 years or older from Hengli Town in Southern China was conducted. Participants underwent standard interviews, physical measurements, laboratory tests, and comprehensive eye examinations. Low vision and blindness were defined based on WHO criteria. Visual acuity data were available for 1348 (89.9%) of the 1500 subjects with type 2 diabetes...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28893702/risk-factors-associated-with-perioperative-myocardial-infarction-in-major-open-vascular-surgery
#9
Danielle C Sutzko, Elizabeth A Andraska, Andrea T Obi, Peter K Henke, Nicholas H Osborne
BACKGROUND: Among patients undergoing non-cardiac surgery, major vascular surgery is associated with a high risk of perioperative myocardial infarction (MI). Currently there are no perioperative MI risk calculators accounting for intraoperative and postoperative risk factors in vascular surgery patients. We aimed to investigate specific risk factors for perioperative MI after major open vascular surgery to determine which patients are at highest risk of MI, and the association of perioperative MI with perioperative transfusion...
September 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28890154/diabetes-mellitus-in-intraductal-papillary-mucinous-neoplasm-of-the-pancreas-is-associated-with-high-grade-dysplasia-and-invasive-carcinoma
#10
Vicente Morales-Oyarvide, Mari Mino-Kenudson, Cristina R Ferrone, Dushyant V Sahani, Ilaria Pergolini, Adrián A Negreros-Osuna, Andrew L Warshaw, Keith D Lillemoe, Carlos Fernández-Del Castillo
BACKGROUND: While the association between Diabetes Mellitus (DM) and pancreatic ductal adenocarcinoma is well recognized, its importance in intraductal papillary mucinous neoplasm of the pancreas (IPMN) is not well-defined. We sought to examine the associations of DM with degree of dysplasia and morphological subtypes in IPMN. METHODS: In 454 patients with resected IPMN, we evaluated associations of DM with high-grade dysplasia (HGD), invasive carcinoma, precursor epithelial subtype (gastric, intestinal, oncocytic, pancreatobiliary), and histological type of invasive carcinomas (tubular, colloid, oncocytic) using logistic regression...
September 7, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28887250/analysis-of-patients-undergoing-major-lower-extremity-amputation-in-the-vascular-quality-initiative
#11
Joshua Gabel, Brice Jabo, Sheela Patel, Sharon Kiang, Christian Bianchi, Jason Chiriano, Theodore Teruya, Ahmed M Abou-Zamzam
BACKGROUND: Despite an aggressive climate of limb salvage and revascularization, 7% of patients with peripheral artery disease undergo major lower extremity amputation (LEA). The purpose of this study was to describe the current demographics and early outcomes of patients undergoing major LEA in the Vascular Quality Initiative (VQI). METHODS: The VQI amputation registry was reviewed to identify patients who underwent major LEAs. Patient factors, limb characteristics, procedure type, and intraoperative variables were analyzed by level of amputation...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28884820/endoluminal-weight-loss-and-metabolic-therapies-current-and-future-techniques
#12
REVIEW
Christine Hill, Mouen A Khashab, Anthony N Kalloo, Vivek Kumbhari
Obesity is a public health epidemic associated with a number of comorbidities, most notably type 2 diabetes and hypertension, as well as elevated all-cause mortality. The treatment for obesity and its associated comorbidities has most recently expanded into the field of bariatric endoscopy. This field bridges a gap between lifestyle counseling with or without pharmaceutical treatment and the most effective treatment of obesity, bariatric surgery. Because of its minimally invasive nature, bariatric endoscopic therapy has the potential to appeal to the large sector of the obese population that resists surgery, as well as those early in the onset of obesity...
September 8, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28883842/diabetes-as-a-risk-factor-of-hospitalization-in-the-surgical-ward-due-to-cancer-in-the-elderly-and-middle-aged-population
#13
Mariusz Dąbrowski, Alina Grondecka
INTRODUCTION: Diabetes can be considered as a risk factor of several types of malignancy. Surgery is one of the primary methods of cancer treatment. The objective of this study was to evaluate the association between diabetes and hospital admissions to the surgery unit due to malignancy among elderly and middle-aged people. MATERIAL AND METHODS: Data for analysis were taken from the medical records of 7,694 patients aged > 45, hospitalized in the General Surgery Ward in the Specialist District Hospital in Stalowa Wola in the Subcarpathian (Podkarpacie) Province, Poland, in the years 2010-2013...
August 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28869031/cost-analysis-of-bariatric-surgery-in-denmark-made-with-a-decision-analytic-model
#14
Oleg Borisenko, Vasily Lukyanov, Søren Paaske Johnsen, Peter Funch-Jensen
INTRODUCTION: Bariatric surgery offers effective obesity treatment. The aim of this study was to evaluate the cost-effectiveness of bariatric surgery in Denmark from a third-party payer perspective in the mid- (ten years) and long-term (lifetime). METHODS: A state-transition Markov model was developed in which patients may experience surgery, post-surgery complications, diabetes mellitus type 2, cardiovascular diseases or die. Transition probabilities, costs and utilities were informed by the literature...
August 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28852591/the-effects-of-allogenic-stem-cells-in-a-murine-model-of-hind-limb-diabetic-ischemic-tissue
#15
Jesús Álvarez García, Soledad García Gómez-Heras, Luis Riera Del Moral, Carlota Largo, Damián García-Olmo, Mariano García-Arranz
BACKGROUND: Diabetes is one of the major risk factors for peripheral arterial disease. In patients in whom surgery cannot be performed, cell therapy may be an alternative treatment. Since time is crucial for these patients, we propose the use of allogenic mesenchymal cells. METHODS: We obtained mesenchymal cells derived from the fat tissue of a healthy Sprague-Dawley rat. Previous diabetic induction with streptozotocin in 40 male Sprague-Dawley rats, ligation plus left iliac and femoral artery sections were performed as a previously described model of ischemia...
2017: PeerJ
https://www.readbyqxmd.com/read/28851712/down-regulation-of-insulin-sensitivity-after-oral-glucose-administration-evidence-for-the-anti-incretin-effect
#16
Serenella Salinari, Geltrude Mingrone, Alessandro Bertuzzi, Elena Previti, Esmeralda Capristo, Francesco Rubino
Intestinal nutrients stimulate insulin-secretion more potently than intravenous glucose administration under similar plasma glucose levels ("incretin effect"). According to the "anti-incretin theory", intestinal nutrients should also cause reduction of insulin sensitivity and/or secretion ("anti-incretin effect") to defend against hyperinsulinemia-hypoglycemia. An exaggerated anti-incretin effect could contribute to insulin resistance/type 2 diabetes while reduction of anti-incretin signals might explain diabetes improvement after bariatric surgery...
August 29, 2017: Diabetes
https://www.readbyqxmd.com/read/28843985/laparoscopic-sleeve-gastrectomy-for-diabetics-5-year-outcomes
#17
Yonatan Lessing, Niv Pencovich, Guy Lahat, Joseph M Klausner, Subhi Abu-Abeid, Shai Meron Eldar
OBJECTIVE: Although the laparoscopic sleeve gastrectomy (SG) is increasingly performed for morbid obesity, gastric bypass is still considered by many to be the gold standard procedure for obese diabetic patients. The aim of this study was to assess the long-term results of SG in morbidly obese patients with type 2 diabetes. METHODS: Diabetic patients who underwent SG at a single center between 2009 and 2011 were included. Outcomes assessed included postoperative complications, weight loss, and resolution or improvement in co-morbidities with an emphasis on diabetes, including glycated hemoglobin (HbA1C) and medication status...
July 18, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28842774/the-impact-of-bariatric-surgery-on-insulin-treated-type-2-diabetes-patients
#18
Rodrigo Lemus, Dror Karni, Dennis Hong, Scott Gmora, Ruth Breau, Mehran Anvari
INTRODUCTION: Bariatric surgery has been shown to lead to significant improvement in glucose homeostasis, resulting in greater rates of type 2 diabetes mellitus (T2DM) remission. While there is substantial evidence of the benefits of bariatric/metabolic surgery in obese diabetic patients on oral therapy (O-T2D), more evidence is necessary in the case of insulin-treated type 2 diabetes (I-T2D) patients and the selection of surgical procedure. METHODS: Analysis of the Ontario Bariatric Registry data was performed, comparing outcomes of Roux-en-Y-gastric bypass (RYGB) and sleeve gastrectomy (SG) on insulin-treated versus non-insulin-treated T2DM patients...
August 25, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28842086/comparison-of-time-to-operation-and-efficacies-of-ultrasound-guided-nerve-block-and-general-anesthesia-in-emergency-external-fixation-of%C3%A2-lower-leg-fractures-ao-42-43-44
#19
Chan Kang, Sang-Bum Kim, Youn-Moo Heo, You-Gun Won, Byung-Hak Oh, June-Bum Jun, Gi-Soo Lee
The present randomized controlled trial evaluated the usefulness of ultrasound (US)-guided nerve block (NB) for emergency external fixation of lower leg fractures, by investigating the time required before surgery and the clinical results stratified by the anesthesia method (US-guided NB or general anesthesia [GA]). From June 2014 to April 2016, 40 patients who had undergone emergency surgery for external fixator application were enrolled in the present study. We measured the lead time before the start of surgery after the decision to perform emergency surgery in both groups...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28840471/the-effects-of-duodenojejunal-omega-switch-in-combination-with-high-fat-diet-and-control-diet-on-incretins-body-weight-and-glucose-tolerance-in-sprague-dawley-rats
#20
Dominika Stygar, Tomasz Sawczyn, Bronisława Skrzep-Poloczek, Aleksander J Owczarek, Natalia Matysiak, Marek Michalski, Łukasz Mielańczyk, Barbara Bażanów, Paweł Ziora, Piotr Choręza, Bogdan Doleżych, Konrad Wojciech Karcz
BACKGROUND: Despite excellent results of bariatric surgery in the treatment of type 2 diabetes and weight loss in human subjects, some patients do not obtain desired results. One of the reasons for this is that not all patients follow caloric intake recommendations. AIM: The aim of this study was to investigate the effect of duodenojejunal omega switch (DJOS) surgery on body weight, glucose tolerance, and incretins in rats. METHODS: DJOS and SHAM surgery were performed on rats maintained for 8 weeks on high-fat diet (HF) and control diet (CD), respectively...
August 24, 2017: Obesity Surgery
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