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https://www.readbyqxmd.com/read/29140860/central-serous-chorioretinopathy-associated-with-fingolimod-treatment
#1
Karima S Khimani, Rod Foroozan
No abstract text is available yet for this article.
November 14, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29137016/binding-pancreaticogastrostomy-anastomosis-in-central-pancreatectomy-a-single-center-experience
#2
Pengcheng Kang, Zhidong Wang, Kaiming Leng, Xiangyu Zhong, Hao Wang, Ming Wan, Sheng Tai, Yunfu Cui
A growing number of central pancreatectomies are performed. However, reconstruction of pancreaticoenteral digestive continuity after central pancreatectomy remains debated. This study evaluates the short-term outcomes of binding pancreaticogastrostomy anastomosis in central pancreatectomy.We have reviewed our experience with 52 patients who underwent binding pancreaticogastrostomy following central pancreatectomy from February 2009 to March 2015. Indication includes 6 noninvasive intraductal papillary mucinous neoplasms, 11 neuroendocrine tumors, 12 solid pseudopapillary tumor, 9 serous cystadenoma, 6 mucinous cystadenoma, and 8 focal pancreatic traumas...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135888/exit-strategy-in-a-treat-and-extend-regimen-for-exudative-age-related-macular-degeneration
#3
Petra Arendt, Siqing Yu, Marion R Munk, Andreas Ebneter, Sebastian Wolf, Martin S Zinkernagel
PURPOSE: To evaluate the outcome of an exit strategy in a treat-and-extend regimen for neovascular age-related macular degeneration. METHODS: Five hundred and ninety-eight eyes of 488 patients with neovascular age-related macular degeneration receiving intravitreal anti-vascular endothelial growth factor injections according to a treat-and-extend regimen were included in this retrospective study. A treat-and-extend regimen with either interval extension by 2 weeks or shortening by 1 week was used...
November 9, 2017: Retina
https://www.readbyqxmd.com/read/29135799/peripapillary-pachychoroid-syndrome
#4
Nopasak Phasukkijwatana, K Bailey Freund, Rosa Dolz-Marco, Mayss Al-Sheikh, Pearse A Keane, Catherine A Egan, Sandeep Randhawa, Jay M Stewart, Qingyun Liu, Alex P Hunyor, Allan Kreiger, Aaron Nagiel, Robert Lalane, Mansour Rahimi, Won Ki Lee, Lee Merrill Jampol, David Sarraf
PURPOSE: To describe the features of peripapillary pachychoroid syndrome (PPS), a novel pachychoroid disease spectrum (PDS) entity. METHODS: Medical records of 31 eyes (16 patients) with choroidal thickening associated with intraretinal and/or subretinal fluid in the nasal macula extending from the disk were reviewed (patients with PPS). Choroidal thickness was compared with 2 age-matched cohorts: typical PDS (17 eyes with central serous chorioretinopathy or pachychoroid neovasculopathy) and 19 normal eyes...
November 10, 2017: Retina
https://www.readbyqxmd.com/read/29135305/choroidal-thickness-of-helicobacter-positive-patients-without-central-serous-chorioretinopathy
#5
Fatih Horozoglu, Ozkan Sever, Ekrem Celik, Rafet Mete, Ertan Sahin
PURPOSE: To evaluate the effect of Helicobacter pylori (H. pylori) infection on subfoveal choroidal thickness (SFCT) in patients without clinical central serous chorioretinopathy (CSC). MATERIALS AND METHODS: This prospective study included 50 patients with pathologically proven H. pylori infection (H. pylori (+)) and 50 patients without H. pylori infection (H. pylori (-)). All of the recruited patients were previously admitted to the Gastroenterology Department of the Namik Kemal University School of Medicine over the period of July 2014 to September 2015...
November 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29134698/central-serous-chorioretinopathy-mimicking-as-choroiditis
#6
Pradeep Kumar Panigrahi, Madan Mohan Mahapatra, Anita Minj, Jasmita Satapathy, Swati Samant
No abstract text is available yet for this article.
November 14, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29126927/mechanisms-of-macular-edema-beyond-the-surface
#7
REVIEW
Alejandra Daruich, Alexandre Matet, Alexandre Moulin, Laura Kowalczuk, Michaël Nicolas, Alexandre Sellam, Pierre-Raphaël Rothschild, Samy Omri, Emmanuelle Gélizé, Laurent Jonet, Kimberley Delaunay, Yvonne De Kozak, Marianne Berdugo, Min Zhao, Patricia Crisanti, Francine Behar-Cohen
Macular edema consists of intra- or subretinal fluid accumulation in the macular region. It occurs during the course of numerous retinal disorders and can cause severe impairment of central vision. Major causes of macular edema include diabetes, branch and central retinal vein occlusion, choroidal neovascularization, posterior uveitis, postoperative inflammation and central serous chorioretinopathy. The healthy retina is maintained in a relatively dehydrated, transparent state compatible with optimal light transmission by multiple active and passive systems...
November 7, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29109866/correlation-between-choroidal-neovascularization-shown-by-oct-angiography-and-choroidal-thickness-in-patients-with-chronic-central-serous-chorioretinopathy
#8
Joanna Gołębiewska, Joanna Brydak-Godowska, Joanna Moneta-Wielgoś, Monika Turczyńska, Dariusz Kęcik, Wojciech Hautz
Purpose: To assess the occurrence of choroidal neovascularization (CNV) secondary to chronic central serous chorioretinopathy (CSCR) using optical coherence tomography angiography (OCTA) and correlate these findings with choroidal thickness (CT). Materials and Methods: This retrospective study included 25 consecutive patients (43 eyes), mean age 48.12 ± 7.8 years, diagnosed with persistent CSCR. All patients underwent a complete ophthalmic examination, fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography, and OCTA...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29098100/chronic-central-serous-chorioretinopathy-in-a-patient-with-pigment-dispersion-syndrome-a-possible-correlation
#9
Dimitrios Kourkoutas, George Tsakonas, Aristotelis Karamaounas, Nikolaos Karamaounas
Chronic central serous chorioretinopathy (CSCR) is a progressive chorioretinopathy with widespread atrophic RPE abnormalities and serous retinal detachments (SRDs) present for 6 months or longer. We report a case of CSCR in a 38-year-old patient with Pigment Dispersion Syndrome (PDS). In the presented case of CSCR, the chronic course of the disease may in part be associated with an underlying generalized degenerative dysfunction of the pigmented cells of the eye on grounds of PDS. We suggest that a chronic course of disease may be suspected in the setting of CSCR with concurrent RPE pathology, such as what is found in PDS...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29095358/comparison-of-short-term-efficacy-between-oral-spironolactone-treatment-and-photodynamic-therapy-for-the-treatment-of-nonresolving-central-serous-chorioretinopathy
#10
Ji Hwan Lee, Sung Chul Lee, Hyesun Kim, Christopher Seungkyu Lee
PURPOSE: To compare the short-term therapeutic efficacy of oral spironolactone treatment with that of half-dose photodynamic therapy (PDT) in patients with nonresolving central serous chorioretinopathy. METHODS: This retrospective, interventional, comparative study included 41 patients with nonresolving central serous chorioretinopathy who exhibited subretinal fluid accumulation for more than 3 months. Of the 41 patients, 18 (18 eyes) received oral spironolactone treatment and 23 (23 eyes) received half-dose PDT...
October 30, 2017: Retina
https://www.readbyqxmd.com/read/29095356/ocular-perfusion-pressure-and-choroidal-thickness-in-central-serous-chorioretinopathy-and-pigment-epitheliopathy
#11
Cheolmin Yun, Ji Yun Han, Sungwon Cho, Soon-Young Hwang, Seong-Woo Kim, Jaeryung Oh
PURPOSE: To investigate ocular perfusion pressure (OPP) in patients with central serous chorioretinopathy (CSC) and pigment epitheliopathy (PE). METHODS: In this retrospective study, we included patients with acute idiopathic unilateral CSC and age- and sex-matched normal controls. The patients with CSC were classified into two groups according to the PE presence on their fellow eyes. We compared OPP among CSC patients with or without PE and normal controls. RESULTS: Among a total of 47 patients with CSC, 21 were classified into the PE group and 26 into the non-PE group...
October 31, 2017: Retina
https://www.readbyqxmd.com/read/29089709/co-existence-of-diffuse-serous-cystadenoma-and-pancreatic-neuroendocrine-tumor
#12
Mallika Tewari, Shashikant Patne, Richa Katiyar, Dipanjan Biswas, H S Shukla
Diffuse serous cystic neoplasm (SCN) associated with pancreatic neuroendocrine tumor (PNET) is a rare finding reported previously in only three patients to the best of our knowledge. We herein present one such interesting report of a diffuse serous cystic adenoma (SCA) and co-existent PNET in a 25-year old lady who presented with abdominal pain for past 6 months. A triple-phase pancreatic protocol computed tomography (CT) scan revealed multiple cysts involving the entire pancreas. The cysts were thin walled, ranging from 2 to 8 cm in width, with no calcification or central scar that was confirmed at laparotomy...
October 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29089356/spironolactone-versus-observation-in-the-treatment-of-acute-central-serous-chorioretinopathy
#13
Xinghong Sun, Yuanlu Shuai, Wangyi Fang, Jia Li, Weizhong Ge, Songtao Yuan, Qinghuai Liu
PURPOSE: To evaluate the efficacy of oral spironolactone in patients with acute central serous chorioretinopathy (CSC). METHODS: This is a prospective, randomised controlled clinical study. Thirty patients with acute CSC were the participants, including 18 patients who were treated with spironolactone (40 mg orally, twice daily) for 2 months in the experimental group and 12 patients who received observation in the control group. Main outcome measures included the proportion of eyes achieving complete resolution of subretinal fluid (SRF), changes in central macular thickness (CMT), the height of SRF (SRFH), best corrected visual acuity (BCVA) and subfoveal choroidal thickness (SFCT)...
October 31, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29078198/control-of-innate-like-b-cell-location-for-compartmentalised-igm-production
#14
REVIEW
Lucy H Jackson-Jones, Cécile Bénézech
Natural IgM are crucial for early protection against infection and play an important homeostatic function by clearing dead cells. The production of IgM is ensured by a population of B cells with innate-like properties: their response is rapidly activated by innate signals early during the onset of infection. The main reservoir of innate-like B cells (IBCs) are the serous cavities, but their maintenance and activation depends on their relocation to a variety of lymphoid tissues. Recent advances indicate that fat-associated lymphoid clusters (FALCs) and milky spots contribute to local IgM secretion and play a central role in the localisation and regulation of IBC function...
October 24, 2017: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29077604/twelve-month-efficacy-of-intravitreal-bevacizumab-injection-for-chronic-atypical-or-recurrent-central-serous-chorioretinopathy
#15
Yoo-Ri Chung, Jong Wan Kim, Ji Hun Song, Aram Park, Min Ho Kim
PURPOSE: To evaluate intravitreal bevacizumab (IVB) injection efficacy for the treatment of chronic, atypical, or recurrent central serous chorioretinopathy (CSC). METHODS: Clinical data from 77 eyes of 71 patients with chronic, atypical, or recurrent CSC treated with IVB were retrospectively analyzed. After initial 6-weekly IVB administration until no subretinal fluid remained at the fovea, additional as-needed IVBs were administered, based on optical coherence tomography findings...
October 26, 2017: Retina
https://www.readbyqxmd.com/read/29063192/spectrum-of-retinal-abnormalities-in-renal-transplant-patients-using-chronic-low-dose-steroids
#16
Elon H C van Dijk, Darius Soonawala, Vera Rooth, Carel B Hoyng, Onno C Meijer, Aiko P J de Vries, Camiel J F Boon
PURPOSE: To assess the ophthalmological characteristics of asymptomatic patients with a renal transplant on chronic low-dose steroids for at least the last 2 years prior to examination. METHODS: Cross-sectional study. All patients underwent an extensive ophthalmological examination. RESULTS: Of the 37 included patients [25 male, 12 female; 59 ± 11 years (range, 38-77 years)] ophthalmological phenotyping revealed abnormalities in 22 patients (59%)...
October 23, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29049410/metamorphopsia-associated-with-central-retinal-vein-occlusion
#17
Koichiro Manabe, Rie Osaka, Yuki Nakano, Yukari Takasago, Tomoyoshi Fujita, Chieko Shiragami, Kazuyuki Hirooka, Yuki Muraoka, Akitaka Tsujikawa
This prospective study aimed to investigate metamorphopsia in eyes with central retinal vein occlusion (CRVO) and included 28 eyes (28 patients) with unilateral CRVO that had macular edema (ME) in the acute phase. The ME was treated with anti-vascular endothelial growth factor agents. At baseline and at 1 and 6 months after initiation of treatment, quantitative measurements of metamorphopsia were performed using M-CHARTS and the retinal morphologic changes were examined by optical coherence tomography. At baseline, metamorphopsia was detected on M-CHARTS in 14 (50...
2017: PloS One
https://www.readbyqxmd.com/read/29020431/overloaded-dysfunctional-rpe-leads-to-delayed-absorption-of-subretinal-fluid-after-retinal-detachment-repair
#18
Patrick Oellers, Dean Eliott
Persistent subretinal fluid (SRF) can impair visual recovery after vitrectomy or scleral buckling surgery for rhegmatogenous retinal detachment. Several hypotheses have been proposed for delayed absorption of SRF, but the etiology has not been clearly identified. The authors present a patient with persistent SRF after vitrectomy for retinal detachment who developed central serous chorioretinopathy (CSCR) during the postoperative period in the nonoperative eye. Thus, subclinical retinal pigment epithelial (RPE) dysfunction was likely present in the operative eye, and when overloaded with SRF after retinal detachment repair, this manifested as delayed absorption...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29020429/pachychoroid-pigment-epitheliopathy-associated-with-tamoxifen
#19
Mehmet Giray Ersoz, Serra Arf, Murat Karacorlu, Mumin Hocaoglu, Isil Sayman Muslubas
Pachychoroid pigment epitheliopathy (PPE) is considered to be a forme fruste of central serous chorioretinopathy. Tamoxifen (Soltamax; Midatech Pharma, Raleigh, NC) has an anti-estrogenic effect on cytoplasmic estrogen receptors. Serum total testosterone, cortisol, and cortisone levels increase during tamoxifen therapy. Tamoxifen may cause hormone disturbance leading to the development of disorders in the pachychoroid spectrum. The authors present two cases of PPE associated with tamoxifen therapy. A 65-year-old woman (Patient 1) and a 52-year-old woman (Patient 2) had a recent history of tamoxifen therapy...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29020426/aflibercept-in-serous-foveal-detachment-in-dome-shaped-macula-short-term-results-in-a-retrospective-study
#20
Giovanni Giacomelli, Rita Mencucci, Andrea Sodi, Ilaria Biagini, Giacomo Abbruzzese, Matteo Giuntoli, Stanislao Rizzo, Gianni Virgili
BACKGROUND AND OBJECTIVE: To evaluate short-term efficacy of intravitreal aflibercept (Eylea; Regeneron, Tarrytown, NY) in serous foveal detachment (SFD) in dome-shaped macula (DSM). PATIENTS AND METHODS: A retrospective, noncomparative case series. Three monthly aflibercept injections were administered. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity (BCVA), optical coherence tomography central subfield thickness (CST), and subretinal fluid (SRF) at baseline and at 2 months and 4 months after the last injection were considered for statistical analysis...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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