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https://www.readbyqxmd.com/read/29346241/chronic-central-serous-chorioretinopathy-early-and-late-morphological-and-functional-changes-after-verteporfin-photodynamic-therapy
#1
Pierluigi Iacono, Massimiliano Tedeschi, Barbara Boccassini, Adele Chiaravalloti, Monica Varano, Mariacristina Parravano
PURPOSE: To describe early and late morphological and functional changes in subjects receiving photodynamic therapy (PDT) for chronic central serous chorioretinopathy. METHODS: Patients with chronic central serous chorioretinopathy were prospectively enrolled and received standard PDT. At the baseline examination, each subject underwent complete ophthalmological examination, including best-corrected visual acuity (BCVA) assessment, fluorescein angiography and indocyanine green angiography, spectral domain optical coherence tomography, and microperimetry...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29339644/changes-in-central-macular-thickness-and-retinal-nerve-fiber-layer-thickness-in-eyes-with-vogt-koyanagi-harada-disease-a-2-year-follow-up-study
#2
Yong-Seop Han, Kyung-Sup Shin, Woo-Hyuk Lee, Jung-Yeul Kim
PURPOSE: To investigate the central macular thickness (CMT) and retinal nerve fiber layer (RNFL) thickness in eyes with Vogt-Koyanagi-Harada (VKH) disease associated with optic disc swelling and serous retinal detachment through a 24-month follow-up period. METHODS: We prospectively investigated 28 eyes of 14 treatment-naïve patients with acute VKH disease associated with optic disc swelling and serous retinal detachment and 30 eyes of 15 normal individuals to compare changes in the CMT and average RNFL thickness...
January 16, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29338130/correlation-between-morphological-characteristics-in-spectral-domain-optical-coherence-tomography-different-functional-tests-and-a-patient-s-subjective-handicap-in-acute-central-serous-chorioretinopathy
#3
Bianca S Gerendas, Julia-Sophie Kroisamer, Wolf Buehl, Sandra M Rezar-Dreindl, Katharina M Eibenberger, Eleonore Pablik, Ursula Schmidt-Erfurth, Stefan Sacu
PURPOSE: The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical practice. METHODS: Retinal thickness (RT), the height, area and volume of subretinal fluid (SRF)/pigment epithelium detachments were evaluated using the standardized procedures of the Vienna Reading Center...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29303152/response-of-central-serous-chorioretinopathy-evaluated-by-multimodal-retinal-imaging
#4
R Sacconi, G Baldin, A Carnevali, L Querques, A Rabiolo, G Marchini, F Bandello, G Querques
PurposeTo identify predictive biomarkers of treatment outcomes by multimodal retinal imaging in patients affected by central serous chorioretinopathy (CSC).Patients and methodsIn this interventional non-randomized clinical study, 27 treatment-naive CSC patients were prospectively enrolled and treated with oral eplerenone for 5-13 weeks. Primary outcomes included presence of pathological findings on indocyaine green angiography (ICGA), structural optical coherence tomography (OCT) and OCT-angiography (OCT-A) at baseline associated with different response to the treatment...
January 5, 2018: Eye
https://www.readbyqxmd.com/read/29303148/visual-outcomes-and-anatomic-changes-after-sub-threshold-micropulse-yellow-laser-577-nm-treatment-for-chronic-central-serous-chorioretinopathy-long-term-follow-up
#5
A Arsan, H S Kanar, A Sonmez
PurposeTo analyze the long-term efficacy of 577 nm sub-threshold micropulse yellow laser (SMYL) in the treatment of chronic central serous chorioretinopathy (CCSC) and to evaluate the anatomic outcome, visual results and safety profile of the treatment.Patients and methodsThis prospective study assessed 39 eyes of 39 patients with non-resolving CCSC lasting more than three months. All eyes were treated by using 577 nm SMYL system with 5% duty cycle (DC) and each patients was monitored monthly. The main outcome measures were best-corrected visual acuity (BCVA), contrast sensitivity (CS) and subretinal fluid (SRF) height, central macular thickness (CMT), central macular volume (CMV), total macular volume (TMV), and subfoveal choroidal thickness (SFCT) measured by spectral domain optical coherence tomography (SD-OCT)...
January 5, 2018: Eye
https://www.readbyqxmd.com/read/29301768/topography-guided-identification-of-leakage-point-in-central-serous-chorioretinopathy-a-base-for-fluorescein-angiography-free-focal-laser-photocoagulation
#6
Dmitrii S Maltsev, Alexei N Kulikov, Jay Chhablani
PURPOSE: To identify optical coherence tomography (OCT) findings associated with the leakage points in patients with central serous chorioretinopathy (CSC) to provide fluorescein angiography (FA)-free focal laser photocoagulation (FLP) of the leakage point. METHODS: A retrospective study included 48 patients with CSC (48 eyes). Colocalisation of leakage points with pigment epithelial detachments (PEDs) and with areas of photoreceptor outer segments (PROS) layer thinning was evaluated with OCT...
January 4, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29281053/reported-incidence-and-survival-of-fallopian-tube-carcinomas-a-population-based-analysis-from-the-north-american-association-of-central-cancer-registries
#7
Britton Trabert, Sally B Coburn, Andrea Mariani, Hannah P Yang, Philip S Rosenberg, Gretchen L Gierach, Nicolas Wentzensen, Kathy A Cronin, Mark E Sherman
Background: Recognition that serous tubal intraepithelial carcinoma (STIC) may represent the first manifestation of many high-grade cancers that were once considered ovarian primary tumors has led to changes in diagnostic practices that could dramatically increase the reporting of tubal carcinomas in US population-based cancer registries. Further, increased detection of early-stage tubal carcinomas through increased recognition coupled with meticulous pathology processing protocols raises important unanswered questions about the clinical behavior of such lesions, which can only be answered using large data sets...
December 21, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29279722/current-diagnostic-procedures-for-diagnosing-vertigo-and-dizziness
#8
REVIEW
Leif Erik Walther
Vertigo is a multisensory syndrome that otolaryngologists are confronted with every day. With regard to the complex functions of the sense of orientation, vertigo is considered today as a disorder of the sense of direction, a disturbed spatial perception of the body. Beside the frequent classical syndromes for which vertigo is the leading symptom (e.g. positional vertigo, vestibular neuritis, Menière's disease), vertigo may occur as main or accompanying symptom of a multitude of ENT-related diseases involving the inner ear...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/29260123/photoreceptor-disruption-and-vision-loss-associated-with-central-serous-retinopathy
#9
Lynn W Sun, Joseph Carroll, Brandon J Lujan
Purpose: To present ophthalmic imaging findings in the case of a 40-year-old male with sustained visual loss after a single episode of acute central serous retinopathy (CSR). Observations: A male subject presented with visual acuity decline to 20/50 OS and was diagnosed with acute CSR. The initial pigment epithelial detachment and subretinal fluid resolved within 6 weeks, but visual acuity remained impaired. Using directional optical coherence tomography (D-OCT) and confocal and split-detector adaptive optics scanning light ophthalmoscopy (AOSLO), we imaged pathologic alterations in the photoreceptor mosaic of the affected eye...
December 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29230322/macular-retinal-vessel-oxygen-saturation-elevation-in-chinese-central-serous-chorioretinopathy
#10
Cheng Li, Xiaoxiao Feng, Xin Wen, Xiaobing Qian, Qishan Zheng, Yongguang Yuan, Yue Fu, Wanwen Shao, Yujie Li, Xiaofeng Lin, Qianying Gao
Purpose: To evaluate the retinal vessel oxygen saturation in central serous chorioretinopathy (CSC) cases among the Chinese. Methods: Relative oxygen saturation of retinal blood vessels was measured in 33 Chinese patients with single-eye CSC using the Oxymap T1 retinal oximeter. The contralateral eyes were the control. The mean saturation of the retinal arteriole (AS) and venule (VS), arteriovenous difference (AVS), and arteriole and venule diameters (AD, VD) was analyzed in the optic disc area and macular region...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29209435/diseases-potentially-related-to-flammer-syndrome
#11
REVIEW
Katarzyna Konieczka, Carl Erb
Flammer syndrome (FS) is a prevalent and mostly benign condition. Subjects with FS seem to have a good life expectancy. Nevertheless, FS subjects are at increased risk for certain diseases, mainly when they are challenged by psychological stress or other stimuli such as coldness. FS is related to ocular diseases, such as normal-tension glaucoma, retinitis pigmentosa, central serous chorioretinopathy, optic nerve compartment syndrome, Leber's hereditary optic neuropathy, arterial or venous occlusions in the retina, and choroid and optic nerve head, despite the absence of classical vascular risk factors...
December 2017: EPMA Journal
https://www.readbyqxmd.com/read/29207100/retinal-microvasculature-alteration-in-central-serous-chorioretinopathy
#12
Li Yu, Yi Shao, Yong Chai, Lin-Hong Ye, Qi-Chen Yang, Lei Ye, Qing Yuan, Nan Jiang, Jing-Lin Yi
The aim of the present study was to investigate the changes of retinal microvascular network in patients with central serous chorioretinopathy (CSCR). A total of fifteen patients (right eye) with CSCR and 15 normal controls (right eye) were recruited. We used optical coherence tomography angiography to scan 6x6 mm macular retinal blood flow images with the application of a series of customized image segmentation processing program software to obtain microvascular and macrovascular density, and compared the superficial microvascular (SMIR), superficial macrovascular ring (SMAR) and the superficial total microvascular (STMI) density between CSCR patients and control group...
November 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29206664/chemoresistance-of-gastric-type-mucinous-carcinoma-of-the-uterine-cervix-a-study-of-the-sankai-gynecology-study-group
#13
Atsumi Kojima, Muneaki Shimada, Yoshiki Mikami, Shoji Nagao, Nobuhiro Takeshima, Toru Sugiyama, Norihiro Teramoto, Takako Kiyokawa, Junzo Kigawa, Ryuichiro Nishimura
OBJECTIVE: Gastric-type mucinous carcinoma (GAS) is a novel variant of mucinous carcinoma of the uterine cervix, characterized by aggressive clinical behavior and absence of high-risk human papillomavirus. We conducted this study to evaluate the chemosensitivity of GAS compared with that of usual-type endocervical adenocarcinoma (UEA) in patients who had been enrolled in our previous study. METHODS: Of 52 patients from our previous phase 2 study (SGSG005) of neoadjuvant chemotherapy with docetaxel and carboplatin for stage IB2 to IIB nonsquamous cervical cancer, 47 (stage IB2, 12; stage IIA2, 7; stage IIB, 28) were enrolled in this study with written informed consent...
December 4, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29200818/photodynamic-therapy-combined-with-antivascular-endothelial-growth-factor-treatment-for-recalcitrant-chronic-central-serous-chorioretinopathy
#14
Masumi G Asahi, Andrew T Chon, Esmeralda Gallemore, Ron P Gallemore
Purpose: To determine whether combination photodynamic therapy (PDT) and antivascular endothelial growth factor (VEGF) therapy is effective in the management of chronic central serous chorioretinopathy (CSC) recalcitrant to conventional therapy. Methods: This was a retrospective analysis of eight patients with chronic CSC unresponsive to topical nonsteroidal anti-inflammatory drugs, focal photocoagulation, anti-VEGF alone, or PDT alone. All patients were evaluated with a full ophthalmic examination, spectral-domain optical coherence tomography (OCT), fluorescein angiography (FA), and most with indocyanine green angiography (ICGA) followed by treatment with half-fluence PDT and intravitreal anti-VEGF injection (seven bevacizumab, one aflibercept)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29195727/clinical-and-imaging-findings-of-pattern-dystrophy-subtypes-diagnostic-errors-and-unnecessary-treatment-in-clinical-practice
#15
A Ozkaya, R Garip, H Nur Tarakcioglu, Z Alkin, M Taskapili
PURPOSE: To evaluate the clinical and multimodal imaging findings of various pattern dystrophy (PD) subtypes and report the initial misdiagnosis rate of PD patients resulting in unnecessary treatment in actual clinical practice. METHODS: Retrospective, observational study. Forty eyes of 24 patients with PD were included. The distribution of PD subtypes, optical coherence tomography (OCT) and fundus autofluorescence (FAF) findings, initial misdiagnoses, revised diagnoses, duration between misdiagnosis and revised diagnosis, and unnecessary treatments administered were evaluated over this time-period...
November 28, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29190234/familial-central-serous-chorioretinopathy
#16
Elon H C van Dijk, Rosa L Schellevis, Myrte B Breukink, Danial Mohabati, Greet Dijkman, Jan E E Keunen, Suzanne Yzer, Anneke I den Hollander, Carel B Hoyng, Eiko K de Jong, Camiel J F Boon
PURPOSE: To assess ophthalmologic characteristics in patients and unaffected individuals in families with multiple members affected by central serous chorioretinopathy (CSC), both at presentation and long-term follow-up. METHODS: In 103 subjects from 23 families with at least 2 affected patients with CSC per family, prospective extensive ophthalmologic examination was performed, including best-corrected visual acuity, indirect ophthalmoscopy, digital color fundus photography, optical coherence tomography, fundus autofluorescence, and fluorescein angiography imaging...
November 28, 2017: Retina
https://www.readbyqxmd.com/read/29178892/knobloch-syndrome-associated-with-polymicrogyria-and-early-onset-of-retinal-detachment-two-case-reports
#17
Robert J White, Yao Wang, Peter Tang, Sandra R Montezuma
BACKGROUND: Knobloch Syndrome (KS) is a rare congenital syndrome characterized by occipital skull defects and vitreoretinal degeneration. Retinal detachment (RD) often occurs at the end of the first decade of life or later. Aside from occipital skull defects, central nervous system abnormalities are uncommon. CASE PRESENTATIONS: We report on two siblings with KS. The first, a seven month old male, presented with nystagmus and was found to have a serous RD and a tessellated retinal appearance...
November 25, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29176603/the-association-between-visual-function-and-retinal-structure-in-chronic-central-serous-chorioretinopathy
#18
Aya Sugiura, Ryosuke Fujino, Nobuko Takemiya, Kimiko Shimizu, Masato Matsuura, Hiroshi Murata, Tatsuya Inoue, Ryo Obata, Ryo Asaoka
The purpose of the current study was to investigate the association between visual function and retinal structure in central serous chorioretinopathy (CSC). In 22 eyes of 22 chronic CSC patients with serous retinal detachment at the macula, retinal sensitivity was measured using MP3 microperimetry (NIDEK, Japan) and mean sensitivity within two degrees (MS2), four degrees (MS4) and six degrees (MS6), as well as foveal sensitivity (MS0), were calculated. Retinal structure was measured using optical coherence tomography (OCT, Spectralis, Heidelberg)...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29171944/-central-serous-chorioretinopathy-following-the-use-of-phosphodiesterase-5-inhibitors
#19
C Smal, G Lepièce, S Bonnet
Central serous chorioretinopathy occurs primarily in young caucasian men. It is characterized by the development of a serous detachment of the sensory retina with the apparition of a relative central scotomata. An association with phosphodiesterase 5 inhibitors is reported in some articles. We described two cases of central serous chorioretinopathy following the use of tadalafil and sildenafil.
November 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29166869/multimodal-imaging-of-retinal-pigment-epithelial-detachments-in-patients-with-c3-glomerulopathy-case-report-and-review-of-the-literature
#20
Valeria Kheir, Ali Dirani, Matthieu Halfon, Jean-Pierre Venetz, Georges Halabi, Yan Guex-Crosier
BACKGROUND: To describe the optical coherence tomography angiograhy (OCTA) of drusenoid pigment epithelial detachments (PEDs) in a woman affected by Complement 3 (C3) glomerulopathy, which represents a spectrum of glomerular diseases characterized on fluorescent microscopy by C3 accumulation with absent, or scanty, immunoglobulin deposits. It is due to acquired or genetically defective alternative pathway control and is generally associated with drusen-like deposits in Bruch's membrane, as well as choriocapillaris...
November 22, 2017: BMC Ophthalmology
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