Read by QxMD icon Read

optic pit

Anastasia Pilat, Rebecca J McLean, Frank A Proudlock, Gail D E Maconachie, Viral Sheth, Yusuf A Rajabally, Irene Gottlob
Purpose: To investigate optic nerve (ON) and macular morphology in patients with Parkinson's disease (PD) using spectral-domain optical coherence tomography (SD-OCT). Subjects: Twenty-five participants with PD (19 males and 6 females; mean age 60.79; SD ± 9.24) and 25 sex-, age-, ethnicity-, and refraction-matched healthy controls. Methods: A high-resolution SD-OCT device was used to acquire scans in 25 participants with PD (mean age 60.79; ± SD 9...
August 1, 2016: Investigative Ophthalmology & Visual Science
Robert A Sisk, Okan Toygar
Purpose. To introduce a clinical sign on spectral domain optical coherence tomography (SDOCT), which may indicate high risk for full-thickness macular hole formation after internal limiting membrane (ILM) peeling. Methods. The preoperative SDOCT images of two patients-one with multilaminar hemorrhage from ruptured retinal artery macroaneurysm and one with serous retinal detachment and severe macular schisis from optic pit maculopathy-who developed full-thickness macular hole (FTMH) after ILM peeling were evaluated retrospectively...
2016: Case Reports in Ophthalmological Medicine
Rosa Dolz-Marco, Kenneth Kato, K Bailey Freund, Lawrence A Yannuzzi
PURPOSE: To report a case of unilateral stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) in a young male showing structural changes induced by a Valsalva maneuver. METHODS: Case report of a 26-year-old oboist with SNIFR, including multimodal imaging. Eye-tracked spectral-domain optical coherence tomography (SD-OCT) was used to compare the retinal architecture at rest and during a Valsalva maneuver. RESULTS: Spectral-domain optical coherence tomography showed macular and peripapillary retinoschisis with no signs of pathologic myopia, optic pit, or vitreoretinal traction...
August 23, 2016: Retinal Cases & Brief Reports
Kumar Sambhav, Sandeep Grover, K V Chalam
PURPOSE: Swept Source Optical Coherence Tomography validates lamina cribrosa anomaly in optic disk pit. METHOD: Observational case report. RESULTS: A 25-year-old African American male presented with decreased vision in right eye of 4 days duration. Best corrected visual acuity (BCVA) for distance in right eye was 20/200 and in left eye was 20/20. Dilated fundus examination of right eye showed serous macular detachment of entire posterior pole along with an optic pit on temporal margin of optic disk...
September 22, 2016: Retinal Cases & Brief Reports
Zaria Ali, Mohammad Abdul-Nabi
Optic disc pits are an uncommon congenital abnormality. Patients remain asymptomatic unless they develop maculopathy. We present a rare case of a double optic disc pit of which only three others have been reported worldwide. A 51-year-old gentleman presented with blurred vision. Fundoscopy revealed a right double optic disc pit. Though he was symptomatic there was no evidence of maculopathy. OCT of macula and disc was otherwise unremarkable. Visual field demonstrated a paracentral defect. Although optic disc pits are rare they are still an important clinical entity...
2016: Case Reports in Ophthalmological Medicine
Marta S Figueroa, Jeroni Nadal, Inés Contreras
PURPOSE: To report the results of vitrectomy with platelet-rich plasma (PRP) application and gas tamponade as a rescue therapy in previously vitrectomized eyes with optic disk pit (ODP) maculopathy. METHODS: Three patients with visual loss due to persistent or recurrent ODP maculopathy who had undergone previous vitrectomy were offered application of PRP. Platelet-rich plasma was obtained by centrifugation of a blood sample from each patient. Surgery consisted of vitrectomy and internal limiting membrane peeling if the membrane had not been already removed (in two eyes)...
September 14, 2016: Retinal Cases & Brief Reports
Josef Maertz, Kathrin J Mohler, Jan P Kolb, Thomas Kein, Aljoscha Neubauer, Anselm Kampik, Siegfried Priglinger, Wolfgang Wieser, Robert Huber, Armin Wolf
PURPOSE: To investigate the structural changes of intrapapillary proliferations associated with optic disk pits (ODPs) and optic disk pit maculopathy (ODP-M) using enhanced depth-spectral domain-optical coherence tomography (SD-EDI-OCT) and megahertz optical coherence tomography (MHz-OCT). METHODS: Sixteen eyes of patients with ODPs were studied. Papillary and peripapillary areas were repeatedly examined with SD-EDI-OCT over time. To evaluate swept-source OCT, some of the patients additionally received MHz-OCT-imaging...
September 9, 2016: Retina
Alper Mete, Peykan Türkçüoğlu, Sabit Kimyon, Kıvanç Güngör
PURPOSE: We report the outcomes of three consecutive patients with optic disc pit-associated maculopathy who were treated with 25-gauge pars plana vitrectomy, internal limiting membrane (ILM) peeling, fluid-air exchange, barrage endolaser, and sulfur hexafluoride (SF6) gas tamponade. CASE REPORT: Patients with optic disc pit-associated maculopathy were treated with 25-gauge pars plana vitrectomy followed by ILM peeling, fluid-air exchange, barrage endolaser, and gas tamponade with 20 % SF6...
September 10, 2016: International Ophthalmology
Sabela Carballal, Sandra Maisterra, Antonio López-Serrano, Antonio Z Gimeno-García, María Isabel Vera, José Carlos Marín-Garbriel, José Díaz-Tasende, Lucía Márquez, Marco Antonio Álvarez, Luis Hernández, Luisa De Castro, Jordi Gordillo, Ignasi Puig, Pablo Vega, Marco Bustamante-Balén, Juan Acevedo, Beatriz Peñas, María López-Cerón, Elena Ricart, Miriam Cuatrecasas, Mireya Jimeno, María Pellisé
OBJECTIVE: Outside clinical trials, the effectiveness of chromoendoscopy (CE) for long-standing IBD surveillance is controversial. We aimed to assess the effectiveness of CE for neoplasia detection and characterisation, in real-life. DESIGN: From June 2012 to 2014, patients with IBD were prospectively included in a multicentre cohort study. Each colonic segment was evaluated with white light followed by 0.4% indigo carmine CE. Specific lesions' features were recorded...
September 9, 2016: Gut
Shengyan Yang, Xiaoxiang Xia, Zhe Liu, E Yiwen, Yujin Wang, Chengchun Tang, Wuxia Li, Junjie Li, Li Wang, Changzhi Gu
We experimentally and theoretically demonstrated an approach to achieve multispectral plasmon-induced transparency (PIT) by utilizing meta-molecules that consist of hyperfine terahertz meta-atoms. The feature size of such hyperfine meta-atoms is 400 nm, which is one order smaller than that of normal terahertz metamaterials. The hyperfine meta-atoms with close eigenfrequencies and narrow resonant responses introduce different metastable energy levels, which makes the multispectral PIT possible. In the triple PIT system, the slow light effect is further confirmed as the effective group delay at three transmission windows can reach 7...
November 9, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Hakan Ozdemir, Serra Arf, Omer Uysal
PURPOSE: To evaluate the long-term outcomes of radial optic neurotomy (RON) in patients with optic disk pit maculopathy and to compare the functional and anatomical outcomes of pars plana vitrectomy (PPV) with temporal side single RON versus PPV without RON. METHODS: This retrospective study included 15 eyes of 15 consecutive patients who had surgery for optic disk pit maculopathy. Patients were followed for 12 to 115 months after surgery. Anatomical and functional results were evaluated with optical coherence tomography, MP-1 microperimetry in the central 20°, and measurement of best-corrected visual acuity...
June 14, 2016: Retina
François Aguet, Srigokul Upadhyayula, Raphaël Gaudin, Yi-Ying Chou, Emanuele Cocucci, Kangmin He, Bi-Chang Chen, Kishore Mosaliganti, Mithun Pasham, Wesley Skillern, Wesley R Legant, Tsung-Li Liu, Greg Findlay, Eric Marino, Gaudenz Danuser, Sean Megason, Eric Betzig, Tom Kirchhausen
Membrane remodeling is an essential part for transfer of components to and from the cell surface and membrane-bound organelles, and for changes in cell shape, particularly critical during cell division. Earlier analyses, based on classical optical live-cell imaging, mostly restricted by technical necessity to the attached bottom surface, showed persistent formation of endocytic clathrin pits and vesicles during mitosis. Taking advantage of the resolution, speed, and non-invasive illumination of the newly developed lattice light sheet fluorescence microscope, we reexamined their assembly dynamics over the entire cell surface and showed that clathrin pits form at a lower rate during late mitosis...
August 17, 2016: Molecular Biology of the Cell
Xinxin Hu, Yi Dai, Jost Jonas, Xinghuai Sun
BACKGROUND: The parapapillary gamma zone has recently been defined as the parapapillary region free of Bruch's membrane. Although it has been reported the presence of defects in peripapillary gamma zone, hitherto undescribed is the herniation of the retinal nerve fiver layer tissue into the peripapillary gamma zone defect with the resulting localized defects in the retinal nerve fiber layer. CASE PRESENTATION: Ophthalmoscopy in a 36-year-old man revealed a localized defect of the retinal nerve fiber layer associated with a yellowish-gray lesion at the inferior temporal outer margin of a peripapillary gamma zone...
2016: BMC Ophthalmology
M Storch, N Feltgen, H Hoerauf
Kranenburg's syndrome is defined as central serous detachment associated with an optic disc pit. We report the interesting and very seldom combination of Kranenburg's syndrome and iris-retinochoroidal-coloboma. Reattachment was achieved after vitrectomy, peeling of epiretinal membranes, laser coagulation adjacent and temporal to the optic disc and gas endotamponade. Coincidence of this syndrome with an iris-retinochoroidal-coloboma is extremely rare. Both coloboma and optic disc pit are based on closure defects during week 6 of embryogenesis...
August 11, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Eun Ji Lee, Tae-Woo Kim
PURPOSE: To report a case in which progressive retinal nerve fiber layer (RNFL) atrophy was observed along with enlargement of the peripapillary pit. PATIENTS AND METHODS: A 34-year-old male was diagnosed with primary open-angle glaucoma and followed up for 4 years with regular ophthalmic examinations. Both eyes were myopic (-10 D, OD and -10.5 D, OS), and untreated intraocular pressures were 18 mm Hg (OD) and 16 mm Hg (OS). RESULTS: A subtle depression of the superotemporal peripapillary area was deepened and emerged as a peripapillary pit during the follow-up period...
August 10, 2016: Journal of Glaucoma
Masatoshi Haruta, Ryoji Yamakawa
PURPOSE: To evaluate the efficacy of vitrectomy in the treatment of macular retinoschisis without a detectable optic disk pit. METHODS: This retrospective interventional case series included eight patients with acquired, unilateral macular retinoschisis with or without foveal detachment. Patients with an optic disk pit, vitreomacular traction, or high myopia were excluded. Six of the eight patients underwent vitrectomy with internal limiting membrane peeling and fluid-air exchange...
August 9, 2016: Retina
Sheng-Xuan Xia, Xiang Zhai, Ling-Ling Wang, Bin Sun, Jian-Qiang Liu, Shuang-Chun Wen
To achieve plasmonically induced transparency (PIT), general near-field plasmonic systems based on couplings between localized plasmon resonances of nanostructures rely heavily on the well-designed interantenna separations. However, the implementation of such devices and techniques encounters great difficulties mainly to due to very small sized dimensions of the nanostructures and gaps between them. Here, we propose and numerically demonstrate that PIT can be achieved by using two graphene layers that are composed of a upper sinusoidally curved layer and a lower planar layer, avoiding any pattern of the graphene sheets...
August 8, 2016: Optics Express
Hui Xu, Hongjian Li, Boxun Li, Zhihui He, Zhiquan Chen, Mingfei Zheng
We investigate a classic optical effect based on plasmon induced transparency (PIT) in a metal-insulator-metal (MIM) bus waveguide coupled with a single defective cavity. With the coupled mode theory (CMT), a theoretical model, for the single defective cavity, is established to study spectral features in the plasmonic waveguide. We can achieve a required description for the phenomenon, and the theoretical results also agree well with the finite-difference time-domain (FDTD) method. Our researches show that the defect's position and size play important roles in the PIT phenomenon...
2016: Scientific Reports
Jerzy Nawrocki, Karolina Bonińska, Zofia Michalewska
No abstract text is available yet for this article.
July 28, 2016: Retina
Paul Free, Gao Conger, Wu Siji, Jing Bo Zhang, David G Fernig
The stability of gold nanorods was assessed following coating with various charged or uncharged ligands, mostly peptides. Highly stable monodispersed gold nanorods were obtained by coating CTAB-stabilized gold nanorods with a pentapeptide with C-terminal ethylene glycol units (peptide-EG). UV-vis spectroscopy of these nanorods suspended in saline solutions indicated no signs of aggregation, and they were easily purified using size-exclusion chromatography. A more stringent measure of nanorod stability involved observing changes in the UV-vis absorbance of gold nanorods subjected to etching with cyanide...
October 1, 2016: Colloids and Surfaces. B, Biointerfaces
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"