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adaptative optics

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https://www.readbyqxmd.com/read/29142643/verification-of-a-computer-aided-replica-technique-for-evaluating-prosthesis-adaptation-using-statistical-agreement-analysis
#1
Hang-Nga Mai, Kyeong Eun Lee, Kyu-Bok Lee, Seung-Mi Jeong, Seok-Jae Lee, Cheong-Hee Lee, Seo-Young An, Du-Hyeong Lee
PURPOSE: The purpose of this study was to evaluate the reliability of computer-aided replica technique (CART) by calculating its agreement with the replica technique (RT), using statistical agreement analysis. MATERIALS AND METHODS: A prepared metal die and a metal crown were fabricated. The gap between the restoration and abutment was replicated using silicone indicator paste (n = 25). Gap measurements differed in the control (RT) and experimental (CART) groups...
October 2017: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/29141905/adaptive-optics-imaging-of-inherited-retinal-diseases
#2
REVIEW
Michalis Georgiou, Angelos Kalitzeos, Emily J Patterson, Alfredo Dubra, Joseph Carroll, Michel Michaelides
Adaptive optics (AO) ophthalmoscopy allows for non-invasive retinal phenotyping on a microscopic scale, thereby helping to improve our understanding of retinal diseases. An increasing number of natural history studies and ongoing/planned interventional clinical trials exploit AO ophthalmoscopy both for participant selection, stratification and monitoring treatment safety and efficacy. In this review, we briefly discuss the evolution of AO ophthalmoscopy, recent developments and its application to a broad range of inherited retinal diseases, including Stargardt disease, retinitis pigmentosa and achromatopsia...
November 15, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29140817/new-developments-in-optical-coherence-tomography-imaging-for-glaucoma
#3
Jean-Claude Mwanza, Donald L Budenz
PURPOSE OF REVIEW: Since its introduction in ophthalmology, optical coherence tomography (OCT) has undergone significant advances in imaging protocols, algorithms, and addition of new parameters which have maximized its potential for diagnosing, evaluating the response to treatment, and assessing the progression of various ocular diseases, including glaucoma. This review provides an update on recent developments in OCT with respect to the management of glaucoma. RECENT FINDINGS: Most recent notable developments include the introduction of the minimum distance band, which is a three-dimensional optic nerve head parameter, and Swept-Source OCT with its single wide-field scanning capability...
November 14, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29140304/ultra-fast-microwave-synthesis-of-zno-nanorods-on-cellulose-substrates-for-uv-sensor-applications
#4
Ana Pimentel, Ana Samouco, Daniela Nunes, Andreia Araújo, Rodrigo Martins, Elvira Fortunato
In the present work, tracing and Whatman papers were used as substrates to grow zinc oxide (ZnO) nanostructures. Cellulose-based substrates are cost-efficient, highly sensitive and environmentally friendly. ZnO nanostructures with hexagonal structure were synthesized by hydrothermal under microwave irradiation using an ultrafast approach, that is, a fixed synthesis time of 10 min. The effect of synthesis temperature on ZnO nanostructures was investigated from 70 to 130 °C. An Ultra Violet (UV)/Ozone treatment directly to the ZnO seed layer prior to microwave assisted synthesis revealed expressive differences regarding formation of the ZnO nanostructures...
November 15, 2017: Materials
https://www.readbyqxmd.com/read/29139480/position-paper-the-potential-role-of-optical-biopsy-in-the-study-and-diagnosis-of-environmental-enteric-dysfunction
#5
REVIEW
Alex J Thompson, Michael Hughes, Salzitsa Anastasova, Laurie S Conklin, Tudor Thomas, Cadman Leggett, William A Faubion, Thomas J Miller, Peter Delaney, François Lacombe, Sacha Loiseau, Alexander Meining, Rebecca Richards-Kortum, Guillermo J Tearney, Paul Kelly, Guang-Zhong Yang
Environmental enteric dysfunction (EED) is a disease of the small intestine affecting children and adults in low and middle income countries. Arising as a consequence of repeated infections, gut inflammation results in impaired intestinal absorptive and barrier function, leading to poor nutrient uptake and ultimately to stunting and other developmental limitations. Progress towards new biomarkers and interventions for EED is hampered by the practical and ethical difficulties of cross-validation with the gold standard of biopsy and histology...
November 15, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29139045/electroretinography-in-idiopathic-intracranial-hypertension-comparison-of-the-pattern-erg-and-the-photopic-negative-response
#6
Jason C Park, Heather E Moss, J Jason McAnany
PURPOSE: To evaluate the relationship between electrophysiological measures of retinal ganglion cell (RGC) function in patients who have idiopathic intracranial hypertension (IIH). METHODS: The pattern electroretinogram (pERG) and photopic negative response (PhNR) were recorded from 11 IIH patients and 11 age-similar controls. The pERG was elicited by a contrast-reversing checkerboard. The PhNR, a slow negative component following the flash ERG b-wave, was recorded in response to a long-wavelength flash presented against a short-wavelength adapting field...
November 14, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29138314/imaging-and-quantifying-ganglion-cells-and-other-transparent-neurons-in-the-living-human-retina
#7
Zhuolin Liu, Kazuhiro Kurokawa, Furu Zhang, John J Lee, Donald T Miller
Ganglion cells (GCs) are fundamental to retinal neural circuitry, processing photoreceptor signals for transmission to the brain via their axons. However, much remains unknown about their role in vision and their vulnerability to disease leading to blindness. A major bottleneck has been our inability to observe GCs and their degeneration in the living human eye. Despite two decades of development of optical technologies to image cells in the living human retina, GCs remain elusive due to their high optical translucency...
November 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29136837/optical-molecular-analysis-using-office-flatbed-photo-scanner-new-approaches-and-solutions
#8
K V Oskolok, E V Shults, O V Monogarova, A A Chaplenko
The design and operations principles of a prototype of optical device based on an office flatbed photo scanner with a slide adapter are described in the paper. The developed device is intended for the analysis of liquid-phase samples by colorimetry, photometry, fluorimetry and nephelometry. Teflon cassettes designed for fixing cuvettes on glass plate of the scanner. Teflon wedge-shaped inserts for cuvettes have been developed to optimize the conditions of colorimetric analysis. These inserts allow varying the thickness of the absorbing layer of solutions...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29135813/pendular-seesaw-nystagmus-in-a-patient-with-a-giant-pituitary-macroadenoma-pathophysiology-and-the-role-of-the-accessory-optic-system
#9
Peter Yat-Ming Woo, Saori Takemura, Allen Ming-Yan Cheong, Alberto Chi-Ho Chu, Yung Chan, Hoi-Tung Wong, Kwong-Yau Chan
Seesaw nystagmus is characterized by cyclic eye movements with a conjugate torsional component and a dissociated vertical component. In the first half of the cycle, one eye elevates and intorts, whereas the other eye depresses and extorts. The pattern is reversed in the remaining half of the cycle. We describe a patient with a giant pituitary adenoma who developed pendular seesaw nystagmus. Disturbance in the visuovestibular system is postulated to contribute to this form of seesaw nystagmus. Lesions compressing the optic chiasm and the accessory optic system could interrupt the transmission of retinal error signals to the inferior olivary nucleus and the interstitial nucleus of Cajal, thus interfering with the adaptive mechanism of the vestibulo-ocular reflex and leading to pendular seesaw nystagmus...
November 9, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29131635/temperature-dependent-coercive-field-measured-by-a-quantum-dot-strain-gauge
#10
Yan Chen, Yang Zhang, Robert Keil, Michael Zopf, Fei Ding, Oliver G Schmidt
Coercive fields of piezoelectric materials can be strongly influenced by environmental temperature. We investigate this influence using a heterostructure consisting of a single crystal piezoelectric film and a quantum dots containing membrane. Applying electric field leads to a physical deformation of the piezoelectric film, thereby inducing strain in the quantum dots and thus modifying their optical properties. The wavelength of the quantum dot emission shows butterfly-like loops, from which the coercive fields are directly derived...
November 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/29130305/tuning-the-sensing-performance-of-multilayer-plasmonic-core-satellite-assemblies-for-rapid-detection-of-targets-from-lysed-cells
#11
Nguyen Hoang Le, Bach Kim Nguyen, Gang Ye, Chun Peng, Jennifer I L Chen
Optical sensors based on discrete plasmonic nanostructures are invaluable for probing biomolecular interactions when applied as plasmonic rulers or reconfigurable multi-nanoparticle assemblies. However, their adaptation as a versatile sensing platform is limited by the research-grade instrumentation required for single-nanostructure imaging and/or spectroscopy and complex data fitting and analysis. Additionally, the dynamic range is often too narrow for the quantitative analysis of targets of interest in biodiagnostics, food safety or environmental monitoring...
November 13, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29127235/cardiac-performance-is-limited-by-oxygen-delivery-to-the-mitochondria-in-the-crystalloid-perfused-working-heart
#12
Sarah Kuzmiak-Glancy, Raul Covian, Armel N Femnou, Brian Glancy, Rafael Jaimes, Anastasia M Wengrowski, Kara Garrott, Stephanie French, Robert S Balaban, Matthew W Kay
The left ventricular (LV) working, crystalloid-perfused heart is used extensively to evaluate basic cardiac function, pathophysiology, and pharmacology. Crystalloid-perfused hearts may be limited by oxygen delivery, as adding oxygen carriers increases myoglobin oxygenation and improves myocardial function. However, whether decreased myoglobin oxygen saturation impacts oxidative phosphorylation (OxPhos) is unresolved since myoglobin has a much lower affinity for oxygen than cytochrome c oxidase (COX). In the present study, a laboratory-based synthesis of an affordable perfluorocarbon (PFC) emulsion was developed to increase perfusate oxygen-carrying capacity without impeding optical absorbance assessments...
November 10, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29124422/perifoveal-interdigitation-zone-loss-in-hydroxychloroquine-toxicity-leads-to-subclinical-bull-s-eye-lesion-appearance-on-near-infrared-reflectance-imaging
#13
Avenell L Chew, Danuta M Sampson, Enid Chelva, Jane C Khan, Fred K Chen
PURPOSE: To characterize the ultrastructural and functional correlates of hydroxychloroquine (HCQ)-induced subclinical bull's eye lesion seen on near-infrared reflectance (NIR) imaging. METHODS: An asymptomatic 54-year-old male taking HCQ presented with paracentral ring-like scotoma, abnormal multifocal electroretinography (mfERG) and preserved ellipsoid zone on optical coherence tomography (OCT). Dense raster OCT was performed to create en face reflectivity maps of the interdigitation zone...
November 9, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29121482/feasibility-of-coupling-a-thermal-optical-carbon-analyzer-to-a-quadrupole-mass-spectrometer-for-enhanced-pm2-5-speciation
#14
Gustavo M Riggio, Judith C Chow, Paul M Cropper, Xiaoliang Wang, Reddy L N Yatavelli, Xufei Yang, John G Watson
A thermal/optical carbon analyzer (TOA), normally used for quantification of organic carbon (OC) and elemental carbon (EC) in PM2.5 speciation networks, was adapted to direct thermally-evolved gases to an electron impact quadrupole mass spectrometer (QMS), creating a TOA-QMS. This approach produces spectra similar to those obtained by the Aerodyne Aerosol Mass Spectrometer (AMS), but the ratios of the mass to charge (m/z) signals differ and must be re-measured using laboratory-generated standards. Linear relationships are found between TOA-QMS signals and ammonium (NH4(+)), nitrate (NO3(-)), and sulfate (SO4(2-)) standards...
November 9, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29120714/functional-magnetic-resonance-imaging-to-assess-neuroadaptation-to-multifocal-intraocular-lenses
#15
Andreia M Rosa, Ângela C Miranda, Miguel M Patrício, Colm McAlinden, Fátima L Silva, Miguel Castelo-Branco, Joaquim N Murta
PURPOSE: To evaluate the use of functional magnetic resonance imaging (MRI) to assess neuroadaptation to multifocal intraocular lenses (IOLs). SETTING: Faculty of Medicine, University of Coimbra, Coimbra, Portugal. DESIGN: Prospective case study. METHODS: Patients with bilateral diffractive IOL implantation after cataract surgery had functional MRI at postoperative intervals of 3 weeks and 6 months. A nonintervention control group was included as proof of concept...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29117417/repeatability-of-a-commercially-available-adaptive-optics-visual-simulator-and-aberrometer-in-normal-and-keratoconic-eyes
#16
Rohit Shetty, Shruti Kochar, Tushar Grover, Pooja Khamar, Pallak Kusumgar, Kanchan Sainani, Abhijit Sinha Roy
PURPOSE: To evaluate the repeatability of aberration measurement obtained by a Hartmann-Shack aberrometer combined with a visual adaptive optics simulator in normal and keratoconic eyes. METHODS: One hundred fifteen normal eyes and 92 eyes with grade I and II keratoconus, as per the Amsler-Krumeich classification, were included in the study. To evaluate the repeatability, three consecutive measurements of ocular aberrations were obtained by a single operator. Zernike analyses up to the 5th order for a pupil size of 4...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29117412/in-vivo-measurement-of-longitudinal-chromatic-aberration-in-patients-implanted-with-trifocal-diffractive-intraocular-lenses
#17
Maria Vinas, Ana Gonzalez-Ramos, Carlos Dorronsoro, Vyas Akondi, Nuria Garzon, Francisco Poyales, Susana Marcos
PURPOSE: To measure the longitudinal chromatic aberration (LCA) by both psychophysical methods and in vivo double-pass retinal imaging in patients bilaterally implanted with trifocal diffractive intraocular lenses (IOLs). METHODS: Measurements were performed with a polychromatic adaptive optics system provided with a supercontinuum laser, a Hartmann-Shack wavefront sensor, a deformable mirror, a motorized Badal system, a pupil monitoring system, a double-pass retinal imaging channel, and a psychophysical channel with monochromatically illuminated stimuli...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29114669/detection-of-single-nucleotide-polymorphism-by-measuring-extension-kinetics-with-t7-exonuclease-mediated-isothermal-amplification
#18
Miao Cui, Xianjin Xiao, Meiping Zhao, Bo Zheng
In this work, we measured the primer extension kinetics of the Klenow fragment (exo-) to achieve rapid detection of single nucleotide polymorphism (SNP). Both the matching and the single-base mismatching targets were used as the primer in the kinetic measurements to identify the single nucleotide polymorphism. By coupling with the T7 exonuclease-assisted target cycling process, we decreased the detection limit but still maintained a high discrimination factor. After the demonstration of a good discrimination ability with synthetic DNA strands, we applied the method to detect low abundance of epidermal growth factor receptor (EGFR) mutation in human genomic DNA, which was a biomarker of non-small cell lung cancer...
November 8, 2017: Analyst
https://www.readbyqxmd.com/read/29113848/high-vacuum-optical-platform-for-cryo-clem-hope-a-new-solution-for-non-integrated-multiscale-correlative-light-and-electron-microscopy
#19
Shuoguo Li, Gang Ji, Yang Shi, Lasse Hyldgaard Klausen, Tongxin Niu, Shengliu Wang, Xiaojun Huang, Wei Ding, Xiang Zhang, Mingdong Dong, Wei Xu, Fei Sun
Cryo-correlative light and electron microscopy (cryo-CLEM) offers a unique way to analyze the high-resolution structural information of cryo-vitrified specimen by cryo-electron microscopy (cryo-EM) with the guide of the search for unique events by cryo-fluorescence microscopy (cryo-FM). To achieve cryo-FM, a trade-off must be made between the temperature and performance of objective lens. The temperature of specimen should be kept below devitrification while the distance between the objective lens and specimen should be short enough for high resolution imaging...
November 4, 2017: Journal of Structural Biology
https://www.readbyqxmd.com/read/29112143/adaptive-monocular-visual-inertial-slam-for-real-time-augmented-reality-applications-in-mobile-devices
#20
Jin-Chun Piao, Shin-Dug Kim
Simultaneous localization and mapping (SLAM) is emerging as a prominent issue in computer vision and next-generation core technology for robots, autonomous navigation and augmented reality. In augmented reality applications, fast camera pose estimation and true scale are important. In this paper, we present an adaptive monocular visual-inertial SLAM method for real-time augmented reality applications in mobile devices. First, the SLAM system is implemented based on the visual-inertial odometry method that combines data from a mobile device camera and inertial measurement unit sensor...
November 7, 2017: Sensors
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