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Tendon injections

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https://www.readbyqxmd.com/read/28332593/injections-through-skin-colonized-with-staphylococcus-aureus-biofilm-introduce-contamination-despite-standard-antimicrobial-preparation-procedures
#1
Yi Wang, Valery Leng, Viraj Patel, K Scott Phillips
While surgical site preparation has been extensively studied, there is little information about resistance of skin microbiota in the biofilm form to antimicrobial decontamination, and there are no quantitative models to study how biofilm might be transferred into sterile tissue/implant materials during injections for joint spine and tendon, aspiration biopsies and dermal fillers (DF). In this work, we develop two in vitro models to simulate the process of skin preparation and DF injection using pig skin and SimSkin (silicone) materials, respectively...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28329480/linear-atrophy-and-vascular-fragility-following-ultrasoundguided-triamcinolone-injection-for-dequervain-tendonitis
#2
Hal B Willardson, Shannon Buck, James Neiner
A 64 year-old woman presented with a one-yearhistory of purpuric, atrophic, linear patches alongthe left lateral forearm. The patient had receivedtwo ultrasound-guided triamcinolone injectionsone year earlier into her left extensor pollicis brevisand abductor pollicis longus tendon sheathsfor DeQuervain tendonitis. In the seven monthsfollowing the second injection, the patient developedatrophy, purpura, and telangiectasias starting at thesite of injection and extending proximally, followingthe course of her left cephalic vein...
January 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28321422/autologous-tenocyte-injection-for-the-treatment-of-chronic-recalcitrant-gluteal-tendinopathy-a-prospective-pilot-study
#3
Thomas A Bucher, Jay R Ebert, Anne Smith, William Breidahl, Michael Fallon, Tao Wang, Ming-Hao Zheng, Gregory C Janes
BACKGROUND: Gluteal tendinopathy is a common cause of lateral hip pain, and existing conservative treatment modalities demonstrate high symptom recurrence rates. Autologous tenocyte injection (ATI) is a promising cell therapy that may be useful for the treatment of gluteal tendinopathy. PURPOSE: To investigate the safety and effectiveness of ATI, specifically in patients with chronic recalcitrant gluteal tendinopathy. STUDY DESIGN: Case series; Level of evidence, 4...
February 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28303297/acute-calcific-tendinopathy-of-the-popliteus-tendon-a-rare-case-diagnosed-using-a-multimodality-imaging-approach-and-treated-conservatively
#4
Cédric Doucet, Akshat Gotra, Santhosh Mauvva Venkatesh Reddy, Mathieu Boily
Acute calcific tendinopathy of the popliteus tendon is a rare medical entity associated with significant patient discomfort. We present the case of a previously healthy 48-year-old female who presented to the emergency department with acute onset of left knee pain. Initial radiographs revealed calcifications within the posterolateral compartment of the knee. Ultrasound imaging demonstrated a swollen and hypoechoic popliteus tendon with an increased color Doppler signal at the periphery of the tendon as well as calcification in the tendon and adjacent soft tissues...
March 16, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28301205/intratendon-delivery-of-leukocyte-poor-platelet-rich-plasma-improves-healing-compared-with-leukocyte-rich-platelet-rich-plasma-in-a-rabbit-achilles-tendinopathy-model
#5
Ruijian Yan, Yanjia Gu, Jisheng Ran, Yejun Hu, Zefeng Zheng, Mengfeng Zeng, Boonchin Heng, Xiao Chen, Zi Yin, Weishan Chen, Weiliang Shen, Hongwei Ouyang
BACKGROUND: Chronic tendinopathy is a commonly occurring clinical problem that affects both athletes and inactive middle-aged patients. Although some studies have shown that different platelet-rich plasma (PRP) preparations could exert various therapeutic effects in vitro, the role of leukocytes in PRP has not yet been defined under tendinopathy conditions in vivo. PURPOSE: This study compared the effects of the intratendon delivery of leukocyte-poor PRP (Lp-PRP) versus leukocyte-rich PRP (Lr-PRP) in a rabbit chronic tendinopathy model in vivo...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296518/effect-of-platelet-rich-plasma-on-rat-achilles-tendon-healing-is-related-to-microbiota
#6
Franciele Dietrich, Malin Hammerman, Parmis Blomgran, Love Tätting, Vinicius Faccin Bampi, Jefferson Braga Silva, Per Aspenberg
Background and purpose - In 3 papers in Acta Orthopaedica 10 years ago, we described that platelet-rich plasma (PRP) improves tendon healing in a rat Achilles transection model. Later, we found that microtrauma has similar effects, probably acting via inflammation. This raised the suspicion that the effect ascribed to growth factors within PRP could instead be due to unspecific influences on inflammation. While testing this hypothesis, we noted that the effect seemed to be related to the microbiota. Material and methods - We tried to reproduce our old findings with local injection of PRP 6 h after tendon transection, followed by mechanical testing after 11 days...
March 15, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28291948/eccentric-training-for-tendon-healing-after-acute-lesion-a-rat-model
#7
Jean-François Kaux, Vincent Libertiaux, Pierre Leprince, Marianne Fillet, Vincent Denoel, Clémence Wyss, Christelle Lecut, André Gothot, Caroline Le Goff, Jean-Louis Croisier, Jean-Michel Crielaard, Pierre Drion
BACKGROUND: The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore, eccentric exercise seems to improve the mechanical quality of the tendon. HYPOTHESIS: A combination of PRP injection and eccentric training might be more effective than either treatment alone. STUDY DESIGN: Controlled laboratory study. METHODS: Adult male rats were anesthetized, an incision was performed in the middle of their left patellar tendon and an injection of physiological fluid (PF) or homologous PRP was randomly made at the lesion level...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28291008/the-efficacy-of-yttrium-90-radiosynovectomy-in-patients-with-camptodactyly-arthropathy-coxa-vara-pericarditis-syndrome
#8
Sulaiman Mohammed Al-Mayouf, Nora Almutairi, Khalid Alismail
OBJECTIVE: Camptodactyly-arthropathy-coxa-vara-pericarditis (CACP) syndrome is an autosomal recessive disorder caused by mutations in PRG4 gene that encodes for proteoglycan 4, the main lubricant for joints and tendon surfaces. It is a non-inflammatory arthropathy, characterized by joint effusions and synovial hypertrophy. So far, there is no effective treatment for this disorder. To evaluate the effectiveness of yttrium-90 radiosynovectomy in arthropathy of patients with CACP syndrome...
February 5, 2017: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/28289610/effect-of-basic-fibroblast-growth-factor-on-achilles-tendon-healing-in-rabbit
#9
Arash Najafbeygi, Mohammad Javad Fatemi, Amir Hussein Lebaschi, Seyed Jaber Mousavi, Seyed Abouzar Husseini, Mitra Niazi
BACKGROUND: Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing which improves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects of basic fibroblast growth factor on the healing of the Achilles tendon in rabbits. METHODS: In 10 New Zealand white rabbits, Achilles tendon was cut at the intersection of the distal and middle thirds on both hind legs...
January 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28272929/perfusion-of-the-rotator-cuff-tendon-according-to-the-repair-configuration-using-an-indocyanine-green-fluorescence-arthroscope
#10
Sae Hoon Kim, Won-Sang Cho, Ho-Yun Joung, Young Eun Choi, Minwoong Jung
BACKGROUND: The disturbance of rotator cuff tendon perfusion has been connected with the suture-bridge configuration repair (SBCR) technique; however, in vivo assessments of the tendon blood supply have been problematic with other modalities. An evaluation of tissue perfusion by an indocyanine green (ICG) fluorescence arthroscope has been developed to counteract this difficulty. PURPOSE: To verify the hindrance of perfusion in SBCR, we used an ICG fluorescence camera to compare parallel-type transosseous repair (PTR) and SBCR in rabbits immediately and at 3 days after rotator cuff repair...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28257671/nonsurgical-management-of-midsubstance-achilles-tendinopathy
#11
REVIEW
Shane McClinton, Lace Luedke, Derek Clewley
Midsubstance Achilles tendinopathy is one of the most common lower leg conditions. Most patients can recover with nonsurgical treatment that focuses on tendon loading exercises and, when necessary, symptom modulating treatments such as topical, oral, or injected medication, ice, shoe inserts, manual therapy, stretching, taping, or low-level laser. If unresponsive to initial management, a small percentage of patients may consider shockwave or sclerosing treatment and possibly surgery.
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28255657/more-histologic-and-ultrastructural-degenerative-signs-in-the-subscapularis-tendon-and-the-joint-capsule-in-male-patients-with-shoulder-impingement
#12
Stefanos Farfaras, Lars Erik Ejerhed, Erling K Hallström, Kjell Hultenby, Khaled Meknas, Tomas Movin, Nikos Papadogiannakis, Jüri-Toomas Kartus
PURPOSE: The purpose of the present study was to analyze biopsy samples from the subscapularis tendon and from the joint capsule from male patients with shoulder impingement syndrome (SAIS) and compare them with samples from male patients with post-traumatic recurrent shoulder instability. The hypothesis of the study was that patients with SAIS would have more histologic and ultrastructural degenerative changes in their subscapularis tendon and joint capsule than patients with post-traumatic recurrent shoulder instability...
March 2, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28251260/intratendinous-adipose-derived-stromal-vascular-fraction-svf-injection-provides-a-safe-efficacious-treatment-for-achilles-tendinopathy-results-of-a-randomized-controlled-clinical-trial-at-a-6-month-follow-up
#13
Federico Giuseppe Usuelli, Miriam Grassi, Camilla Maccario, Marco Vigano', Luciano Lanfranchi, Umberto Alfieri Montrasio, Laura de Girolamo
PURPOSE: Although platelet-rich plasma (PRP) injection has shown controversial results for the treatment of Achilles tendinopathy, it remains the most used biological treatment. Recent findings seem to demonstrate that the stromal vascular fraction (SVF) within adipose tissue may counteract the impaired tendon homeostasis. The aim of this study was to prospectively compare the efficacy of PRP and SVF injection for the treatment of non-insertional Achilles tendinopathy. METHODS: Fourty-four patients were recruited in the study; 23 of them were assigned to the PRP group whereas 21 to the SVF group, treated unilaterally or bilaterally for a total of 28 tendons per group...
March 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28246658/a-review-of-anatomical-placement-of-corticosteroid-injections-for-uncommon-hand-wrist-and-elbow-pathologies
#14
Gregory R Waryasz, Robert Tambone, Todd R Borenstein, Joseph A Gil, Manuel DaSilva
Corticosteroid injections are a common nonsurgical treatment of intersection syndrome, flexor carpi radialis tendonitis, flexor carpi ulnaris tendonitis, and medial epicondylitis. The benefits of corticosteroid injections for these conditions have been well studied and documented in the medical literature. Patients with less common upper extremity complaints usually first present to their primary care provider. A correct anatomical diagnosis will help with early definitive treatment, as the injection must be in the proper location for maximal benefit to the patient...
March 1, 2017: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/28230569/procedure-oriented-torsional-anatomy-of-the-hand-for-spasticity-injection
#15
Joslyn John, John Cianca, Faye Chiou-Tan, Sindhu Pandit, Erin Furr-Stimming, Katherine H Taber
OBJECTIVES: To provide musculoskeletal ultrasound (MSKUS) images of hand anatomy in the position of hemiparetic flexion as a reference for spasticity injections. After a stroke, spasticity can result in anatomic distortion of the hand. Spasticity may require treatment with botulinum toxin or phenol injections. Anatomic distortion may decrease the accuracy of injections. Standard anatomic references are of limited utility because they are not in this spastic hemiparetic position. There presently is no anatomic reference in the literature for these spastic postures...
March 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28229637/a-simple-standard-technique-for-labyrinthectomy-in-the-rat-a-methodical-communication-with-a-detailed-description-of-the-surgical-process
#16
G L Nádasy, G Raffai, E Fehér, G Schaming, E Monos
Aims Labyrinthectomized rats are suitable models to test consequences of vestibular lesion and are widely used to study neural plasticity. We describe a combined microsurgical-chemical technique that can be routinely performed with minimum damage. Methods Caudal leaflet of the parotis is elevated. The tendinous fascia covering the bulla is opened frontally from the sternomastoid muscle's tendon while sparing facial nerve branches. A 4 mm diameter hole is drilled into the bulla's hind lower lateral wall to open the common (in rodents) mastoid-tympanic cavity...
September 2016: Physiol Int
https://www.readbyqxmd.com/read/28221337/modulation-of-digital-flexor-tendon-healing-by-vascular-endothelial-growth-factor-gene-transfection-in-a-chicken-model
#17
W F Mao, Y F Wu, Q Q Yang, Y L Zhou, J B Tang
A major challenge in tendon injury is the weak intrinsic healing capacity of tendon, which may cause re-rupture after surgery. Growth factors are believed to be critical during tendon healing. This study aimed to investigate the effects of vascular endothelial growth factor (VEGF) genes delivered by adeno-associated virus (AAV) vectors on tendon healing and molecular events involved in a chicken model. One hundred and twenty eight deep flexor tendons in the long toes of chickens were completely transected and injected with 2 × 10(9) particles of AAV2-VEGF or saline before surgically repaired...
February 21, 2017: Gene Therapy
https://www.readbyqxmd.com/read/28217565/therapeutic-use-of-hormones-on-tendinopathies-a-narrative-review
#18
REVIEW
Michele Abate, Matteo Guelfi, Andrea Pantalone, Daniele Vanni, Cosima Schiavone, Isabel Andia, Vincenzo Salini
BACKGROUND: Hormones can modify tendon homeostasis, some of them leading to tendon damage, while others are essentials for healing. This narrative review summarizes the current knowledge on the topic, focusing on the hormones normally secreted by endocrine glands. METHODS: A search in PubMed, Web of Knowledge and EMBASE, using the terms tendinopathy or tendon, combined with estrogens, testosterone, thyroid and parathyroid hormones, glucocorticoids and growth hormone, independently, was performed...
October 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28210648/utilization-of-platelet-rich-plasma-for-musculoskeletal-injuries-an-analysis-of-current-treatment-trends-in-the-united-states
#19
Joanne Y Zhang, Peter D Fabricant, Chad R Ishmael, Jeffrey C Wang, Frank A Petrigliano, Kristofer J Jones
BACKGROUND: Platelet-rich plasma (PRP) has emerged as a popular biologic treatment for musculoskeletal injuries and conditions. Despite numerous investigations on the efficacy of PRP therapy, current utilization of this treatment within the United States is not widely known. PURPOSE: To investigate the national utilization of PRP, including the incidence and conditions for which it is used in the clinical setting, and to determine the current charges associated with this treatment...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28209340/ultrasound-guided-injection-for-de-quervain-s-disease-accuracy-and-its-influenceable-anatomical-variances-in-first-extensor-compartment-of-fresh-cadaver-wrists
#20
Jong Woo Kang, Jong Woong Park, Soon Hyuck Lee, Jong Hoon Park, Seung Bum Han, Si Young Park, Woong Kyo Jeong
BACKGROUND: This study was designed to evaluate the accuracy of ultrasound-guided injection targeting EPB tendon sheath and influenceable anatomical variances to the accuracy in the first extensor compartment of fresh cadaver wrists. METHODS: Thirty wrists of 15 cadavers were used. The wrists were divided into right-sided wrists (control group) and left-sided wrists (group A) to compare the accuracy of the manual injection technique (control group) and ultrasound-guided injection technique (group A) targeting EPB tendon sheath...
February 10, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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