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Tendon injections

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https://www.readbyqxmd.com/read/28105983/effect-of-bone-marrow-aspirate-concentrate-platelet-rich-plasma-on-tendon-derived-stem-cells-and-rotator-cuff-tendon-tear
#1
Sun Jeong, Da Hyun, Jong Wook, Silvia Park, Sang Jun
Bone marrow aspirate concentrates (BMACs) and platelet-rich plasma (PRP) are good sources to control the differentiation of tendon derived stem cells (TDSCs) but there has been no study about the effect of BMAC-PRP complex on TDSCs and tendinopathy. The aim of this study was to investigate the effect of BMAC-PRP on the TDSCs and to find the therapeutic effect of BMAC-PRP on the rotator cuff tendon tear. Chondrogenic and osteogenic potential of TDSCs decreased, but adipogenic potential of TDSCs revealed no significant difference when they were co-cultured with BMAC-PRP...
January 20, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28098407/tumefactive-foreign-body-giant-cell-reaction-following-high-pressure-paint-injection-injury-a-case-report-and-review-of-literature
#2
Shakuntala H Mauzo, Michael Swaby, Michael Covinsky
High pressure paint injection injury is an uncommon but well-described injury. The histologic features of long-term paint injection injury with retained material are less recognized. A 46 year old male presented clinically as "recurrent giant cell tumor of tendon sheath". The right index finger demonstrated fusiform enlargement by a pigmented mass with diffuse infiltration into the soft tissue of the hand. Histologically the tumor showed multiple giant cells in a fibrotic stroma extending into the dermis. There were multiple types of foreign material including diffuse brown black pigment, weakly optically polarizing foreign material and white inclusions with a "train track" appearance...
January 18, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28095484/experimental-diabetes-alters-the-morphology-and-nano-structure-of-the-achilles-tendon
#3
Rodrigo Ribeiro de Oliveira, Rômulo Medina de Mattos, Luciana Magalhães Rebelo, Fernanda Guimarães Meireles Ferreira, Fernanda Tovar-Moll, Luiz Eurico Nasciutti, Gerly Anne de Castro Brito
Although of several studies that associate chronic hyperglycemia with tendinopathy, the connection between morphometric changes as witnessed by magnetic resonance (MR) images, nanostructural changes, and inflammatory markers have not yet been fully established. Therefore, the present study has as a hypothesis that the Achilles tendons of rats with diabetes mellitus (DM) exhibit structural changes. The animals were randomly divided into two experimental groups: Control Group (n = 06) injected with a vehicle (sodium citrate buffer solution) and Diabetic Group (n = 06) consisting of rats submitted to intraperitoneal administration of streptozotocin...
2017: PloS One
https://www.readbyqxmd.com/read/28092337/anatomical-basis-and-clinical-application-of-synovial-flaps-in-the-wrist-and-distal-forearm
#4
David L Colen, Jiun-Ting Yeh, Lawrence B Colen
Neuropathic symptoms after median nerve repair at the wrist or secondary to refractory carpal tunnel syndrome may become debilitating. These symptoms develop due to perineural adhesions, intraneural fibrosis and fixation of the nerve to the transverse carpal ligament after surgery and often require neurolysis. Interposition of vascularized soft tissue over the median nerve at the time of neurolysis prevents recurrence of such adhesions. The synovial flap, fashioned from the synovial lining of the flexor tendon sheath, is an ideal tissue for this purpose...
January 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28089496/cell-toxicity-in-fibroblasts-tenocytes-and-human-mesenchymal-stem-cells-a-comparison-of-necrosis-and-apoptosis-inducing-ability-in-ropivacaine-bupivacaine-and-triamcinolone
#5
Anja Z Zhang, Andreas Ficklscherer, Mehmet F Gülecyüz, Alexander C Paulus, Thomas R Niethammer, Volkmar Jansson, Peter E Müller
PURPOSE: To analyze the ability of ropivacaine, bupivacaine, and triamcinolone to induce apoptosis and necrosis in fibroblasts, tenocytes, and human mesenchymal stem cells. METHODS: Human dermal fibroblasts, adipose-derived human mesenchymal stem cells (hMSCs), and tenocytes gained from the rotator cuff tendon were seeded with a cell density of 0.5 × 10(4)/cm(2). One specimen of ropivacaine, bupivacaine, and triamcinolone was tested separately on the cells with separate concentrations of 0...
January 12, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28089102/comparison-of-corticosteroid-autologous-blood-or-sclerosant-injections-for-chronic-tennis-elbow
#6
R Branson, K Naidu, C du Toit, A H Rotstein, R Kiss, D McMillan, L Fooks, B K Coombes, B Vicenzino
OBJECTIVES: To compare three different ultrasound-guided injections for chronic tennis elbow. DESIGN: Assessor-blinded, randomized controlled comparative trial. METHODS: 44 patients with clinically diagnosed tennis elbow, confirmed by Doppler ultrasound, received under ultrasound guidance, a single corticosteroid injection (n=14), or two injections (separated by 4 weeks) of either autologous blood (n=14) or polidocanol (n=16). Clinical and ultrasound examination was performed at baseline, 4, 12 and 26 weeks...
October 29, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28066732/conservative-management-of-tendinopathies-around-hip
#7
REVIEW
Antonio Frizziero, Filippo Vittadini, Andrea Pignataro, Giuseppe Gasparre, Carlo Biz, Pietro Ruggieri, Stefano Masiero
BACKGROUND: The anatomy of hip is widely complex and several anatomical structures interact and contribute to its functioning. For position and role, hip and the surrounding tendons, which have their insertion around, are overstressed and often overloaded, especially in athletes. This could lead to the developing of several tendinopathies, among which the differential diagnosis is often complicated. Many conservative treatments are used in clinical practice, while actually, no defined conservative protocol is recommended...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28061032/effects-of-platelet-rich-plasma-with-concomitant-use-of-a-corticosteroid-on-tenocytes-from-degenerative-rotator-cuff-tears-in-interleukin-1%C3%AE-induced-tendinopathic-conditions
#8
Chris Hyunchul Jo, Seung Yeon Lee, Kang Sup Yoon, Sue Shin
BACKGROUND: A corticosteroid injection is commonly used to treat tendinopathy, but it has been associated with negative effects on tendon homeostasis. Platelet-rich plasma (PRP) is known to have proliferative and anabolic effects as well as cytoprotective effects against corticosteroids on tenocytes. However, the combined effects of a corticosteroid and PRP on the anti-inflammatory, matrix synthesis, and cytoprotective potential of tenocytes in conditions simulating tendinopathy have not been investigated...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28052415/arthroscopic-approach-and-intra-articular-anatomy-of-the-dorsal-and-plantar-synovial-compartments-of-the-bovine-tarsocrural-joint
#9
Hélène Lardé, Sylvain Nichols, Marie Babkine, André Desrochers
OBJECTIVE: To determine arthroscopic approaches to the dorsal and plantar synovial compartments of the tarsocrural joint in adult cattle, and to describe the arthroscopic intra-articular anatomy from each approach. STUDY DESIGN: Ex vivo study. ANIMALS: Fresh adult bovine cadavers (n = 7). METHODS: Two tarsocrural joint were injected with latex to determine arthroscopic portal locations and arthroscopy of the tarsocrural joint of 12 tarsi was performed...
January 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28043311/acromion-types-and-role-of-corticosteroid-with-shoulder-impingement-syndrome
#10
Muhammad Akram, Syed Faraz Ul Hassan Shah Gillani, Faheem Mubashir Farooqi, Syed Muhammad Awais
OBJECTIVE: To determine the association between shoulder impingement and morphological characteristics of acromion and the role of sub-acromial injection of methylprednisolone in the short-term treatment for relieving pain and improve functional disability of these patients. STUDY DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Department of Orthopedic Surgery and Traumatology Unit-I (DOST-I), Mayo Hospital, Lahore, between November 2013 to June 2014...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28042813/the-anatomical-basis-of-paradoxical-masseteric-bulging-after-botulinum-neurotoxin-type-a-injection
#11
Hyung-Jin Lee, In-Won Kang, Kyle K Seo, You-Jin Choi, Seong-Taek Kim, Kyung-Seok Hu, Hee-Jin Kim
The aim of this study was to determine the detailed anatomical structures of the superficial part of the masseter and to elucidate the boundaries and locations of the deep tendon structure within the superficial part of the masseter. Forty-four hemifaces from Korean and Thai embalmed cadavers were used in this study. The deep tendon structure was located deep in the lower third of the superficial part of the masseter. It was observed in all specimens and was designated as a deep inferior tendon (DIT). The relationship between the masseter and DIT could be classified into three types according to the coverage pattern: Type A, in which areas IV and V were covered by the DIT (27%, 12/44); Type B, in which areas V and VI were covered by the DIT (23%, 10/44); and Type C, in which areas IV, V, and VI were covered by the DIT (50%, 22/44)...
December 30, 2016: Toxins
https://www.readbyqxmd.com/read/28040578/analgesia-after-acl-reconstruction-hamstring-donor-site-injection-versus-intra-articular-local-anaesthetic-injection
#12
Bertrand Sonnery-Cottet, Adnan Saithna, Abdul Azeem, Eric Choudja, Jean Baptiste Pic, Julien Cabaton, Mathieu Thaunat
BACKGROUND: The purpose of this study was to compare hamstring donor-site injection versus intra-articular injection of a local anaesthetic for analgesia after anterior cruciate ligament (ACL) reconstruction. HYPOTHESIS: The two methods provide similar pain relief. MATERIAL AND METHODS: 158 consecutive patients undergoing ACL hamstring tendon graft reconstruction (semi-tendinosus/gracilis [STG] or four-stranded semi-tendinosus [ST4]) during two periods in 2015 were included...
December 28, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28035909/comparison-of-the-efficacy-of-lidocaine-and-betamethasone-dipropionate-in-carpal-tunnel-syndrome-injection
#13
Bahar Dernek, Tugba Aydin, Pinar Kursuz Koseoglu, Fatma Nur Kesiktas, Tugba Yesilyurt, Demirhan Diracoglu, Cihan Aksoy
BACKGROUND: Carpal tunnel syndrome (CTS) is a commonly seen peripheral nerve mononeuropathy. Corticosteroid injection within the carpal tunnel is among the conservative treatment options. The exact mechanism of action of steroids is not fully clear; decreased inflammation surrounding nerves or tendons is thought to be the main effect. Lidocaine has been shown to have anti-inflammatory effects on certain cells (monocytes, macrophages, neutrophils etc.). The aim of this study is to evaulate the efficacy of lidocaine treatment as a alternative to corticosteroid treatment in carpal tunnel syndrome...
December 23, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28018840/hand-impairment-in-systemic-sclerosis-various-manifestations-and-currently-available-treatment
#14
Amber Young, Rajaie Namas, Carole Dodge, Dinesh Khanna
Systemic sclerosis (SSc) is an autoimmune disease initially recognized by hand involvement due to characteristic Raynaud's phenomenon (RP), puffy hands, skin thickening, and contractures resembling claw deformities. SSc contributes to hand impairment through inflammatory arthritis, joint contractures, tendon friction rubs (TFRs), RP, digital ulcers (DU), puffy hands, skin sclerosis, acro-osteolysis, and calcinosis. These manifestations, which often co-exist, can contribute to difficulty with occupational activities and activities of daily living (ADL), which can result in impaired quality of life...
September 2016: Current Treatment Options in Rheumatology
https://www.readbyqxmd.com/read/28005449/clinical-benefits-and-drawbacks-of-local-corticosteroids-injections-in-tendinopathies
#15
Michele Abate, Vincenzo Salini, Cosima Schiavone, Isabel Andia
local glucocorticoids injections are widely administered for the treatment of tendinopathies. positive results have been observed in some tendinopathies but not in others. moreover, worsening of symptoms, and even spontaneous tendon ruptures has been reported. the characteristics of the tendinopathies, the clinical peculiarities of the patient, and the technique used to administer glucocorticoids, can influence the therapeutic response. Areas covered: After reviewing the pertinent literature on the clinical results, basic information, both on the pathogenesis of tendinopathies and the effects of glucocorticoids on tendons, is reported...
December 28, 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28004245/repairing-the-ruptured-annular-fibrosus-by-using-type-i-collagen-combined-with-citric-acid-edc-and-nhs-an-in-vivo-study
#16
Yan Wang, Xiaoting Wang, Jin Shang, Huan Liu, Yi Yuan, Yu Guo, Bo Huang, Yue Zhou
OBJECTIVES: To explore the effect of citric acid (CA)-1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC)/N-hydroxysuccinimide (NHS) collagen gel on repairing annular defects. METHODS: Type I collagen was extracted from the rat-tail tendon and crosslinked with CA at different mass ratio using EDC and NHS as crosslinking reagents to prepare four kinds of collagen gels. Forty-eight adult SD rats were divided into first sham group (n = 8), second group (n = 10) which was punctured and injected with CA-EDC/NHS collagen gel, third group (n = 10) which was punctured and injected with CA-EDC/NHS collagen gel, fourth group (n = 10) which was punctured and injected with EDC/NHS collagen gel, and fifth group (n = 10) which was punctured and untreated...
December 21, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28002864/ultrasound-guided-platelet-rich-plasma-treatment-application-and-technique
#17
Kenneth S Lee
Platelet-rich plasma injection is a minimally invasive treatment method for common overuse tendon injuries. This article discusses the biology of platelet-rich plasma (PRP), the healing cascade that PRP promotes, and how PRP composition may differ depending on centrifuge method. It also highlights the common uses of PRP tendon injection and offers an update on the most current clinical evidence-based literature.
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28002863/ultrasound-guided-percutaneous-tenotomy
#18
Jon A Jacobson, Sung Moon Kim, Monica Kalume Brigido
Of the many treatment options for tendinopathy, percutaneous tenotomy has been used throughout the body with success. With this procedure, a needle is repeatedly passed into the abnormal tendon with the goal of converting a chronic degenerative process to an acute inflammatory condition that will progress to tendon healing. Ultrasound guidance for this procedure is essential to ensure that the abnormal region of the tendon is accurately targeted. The treatment has few contraindications, and negligible complications have been described...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28002861/injectable-corticosteroids-take-precautions-and-use-caution
#19
Véronique Freire, Nathalie J Bureau
Corticosteroids are routinely injected into soft tissues, tendon sheaths, bursae, and joints. These anti-inflammatory agents have different potency and solubility, and solubility is inversely correlated with the duration of action. Corticosteroids carry a low risk of complications but commonly cause systemic and local adverse effects. The use of intra-articular corticosteroid injections in the treatment of inflammatory arthritis and osteoarthritis is well established. Evidence also supports the use of injectable corticosteroids in the treatment of inflammatory tenosynovitis and bursitis associated with rheumatic diseases, trigger finger and de Quervain disease, and carpal tunnel syndrome...
November 2016: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/27989921/a-model-system-for-developing-a-tissue-engineered-meniscal-enthesis
#20
Mary Clare McCorry, Melissa M Mansfield, Xiaozhou Sha, Daniel J Coppola, Jonathan W Lee, Lawrence J Bonassar
The meniscus acts as a stabilizer, lubricator, and load distributer in the knee joint. The mechanical stability of the meniscus depends on its connection to the underlying bone by a fibrocartilage to bone transition zone called the meniscal enthesis. Tissue engineered menisci hold great promise as a treatment alternative however lack a means of integrated fixation to the underlying bone needed in order for a tissue engineered meniscal replacement to be successful. Tissue engineering the meniscal enthesis is a difficult task given the complex gradients of cell type, mineral, and extracellular matrix molecules...
October 28, 2016: Acta Biomaterialia
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