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Tendon injections

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https://www.readbyqxmd.com/read/28806826/-treatment-of-dupuytren-s-disease-with-collagenase-injections-in-germany-efficacy-and-adverse-effects-in-110-treated-joints
#1
Adrian Pototschnig, Elias Volkmer, Riccardo E Giunta
Background Since 2011, a new minimally-invasive treatment for Dupuytren's disease has been available in the form of injectable collagenase (Xiapex®, Pfizer). Purpose Our aim is to report about the results and adverse effects of injectable collagenase for the treatment of Dupuytren's disease in Germany. Patients and Methods We treated 78 patients (61 male, 17 female) with 87 injections in 87 digits (little finger n = 40, ring finger n = 37, middle finger n = 8 and index n = 2). We documented the range of motion before treatment, after 6 weeks and after 6 months...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28806095/a-midterm-evaluation-of-postoperative-platelet-rich-plasma-injections-on-arthroscopic-supraspinatus-repair-a-randomized-controlled-trial
#2
Jay R Ebert, Allan Wang, Anne Smith, Robert Nairn, William Breidahl, Ming Hao Zheng, Timothy Ackland
BACKGROUND: Platelet-rich plasma (PRP) has been applied as an adjunct to rotator cuff repair to improve tendon-bone healing and potentially reduce the incidence of subsequent tendon retears. PURPOSE: To investigate whether the midterm clinical and radiographic outcomes of arthroscopic supraspinatus repair are enhanced after repeated postoperative applications of PRP. STUDY DESIGN: Randomized controlled trial; Level of evidence, 1. METHODS: A total of 60 patients (30 control; 30 PRP) were initially randomized to receive 2 ultrasound-guided injections of PRP to the tendon repair site at 7 and 14 days after double-row arthroscopic supraspinatus repair or not...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28774238/wide-awake-hand-surgery
#3
Line Lied, Grethe E Borchgrevink, Vilhjalmur Finsen
BACKGROUND: "Wide awake hand surgery", where surgery is performed in local anaesthesia with adrenaline, without sedation or a tourniquet, has become widespread in some countries. It has a number of potential advantages and we wished to evaluate it among our patients. METHODS: All 122 patients treated by this method during one year were evaluated by the surgeons and the patients on a numerical scale from 0 (best/least) to 10 (worst/most). Theatre time was compared to that recorded for a year when regional or general anaesthesia had been used...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28774233/disruption-of-flexor-tendon-after-intrasheath-triamcinolone-acetonide-injection-for-trigger-digits-two-case-reports
#4
Toshikazu Tanaka, Takeshi Ogawa, Takaji Yanai, Eriko Okano, Sho Kohyama, Naoyuki Ochiai
We experienced two cases of flexor tendons rupture after triamcinolone acetate (TA) injection for trigger finger. A 45-year-old man underwent injection of 40 mg of TA and 1 mL of 1% lidocaine solution into his little finger. While playing golf 3 months after the injection, he heard a popping sound, and was unable to flex it. A 57-year-old female nurse had undergone injection of 40 mg of TA and 1 mL of 1% lidocaine solution into her thumb twice at a 2-month interval. Two months after the second injection, she was unable to flex it...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28771237/mechanical-isolation-and-measurement-of-force-and-myoplasmic-free-ca-2-in-fully-intact-single-skeletal-muscle-fibers
#5
Arthur J Cheng, Håkan Westerblad
Mechanical dissection of single intact mammalian skeletal muscle fibers permits real-time measurement of intracellular properties and contractile function of living fibers. A major advantage of mechanical over enzymatic fiber dissociation is that single fibers can be isolated with their tendons remaining attached, which allows contractile forces (in the normal expected range of 300-450 kN/m(2)) to be measured during electrical stimulation. Furthermore, the sarcolemma of single fibers remains fully intact after mechanical dissection, and hence the living fibers can be studied with intact intracellular milieu and normal function and metabolic properties, as well as ionic control...
September 2017: Nature Protocols
https://www.readbyqxmd.com/read/28765268/the-achilles-tendon-and-the-retrocalcaneal-bursa-an-anatomical-and-radiological-study
#6
P A Pękala, B M Henry, J R Pękala, K Piska, K A Tomaszewski
OBJECTIVES: Inflammation of the retrocalcaneal bursa (RB) is a common clinical problem, particularly in professional athletes. RB inflammation is often treated with corticosteroid injections however a number of reports suggest an increased risk of Achilles tendon (AT) rupture. The aim of this cadaveric study was to describe the anatomical connections of the RB and to investigate whether it is possible for fluid to move from the RB into AT tissue. METHODS: A total of 20 fresh-frozen AT specimens were used...
July 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28763326/point-of-care-ultrasonography-findings-and-care-use-among-patients-undergoing-ultrasound-guided-shoulder-injections
#7
Se Won Lee, Timothy Tiu, Jeremy Roberts, Brian Lee, Matthew N Bartels, Mooyeon Oh-Park
OBJECTIVE: The aims of the study were to assess the overall reduction of pain in patients undergoing ultrasound-guided shoulder injections and to characterize the preinjection point-of-care ultrasound findings and use of clinical services postinjection including the use of magnetic resonance imaging and surgeries. DESIGN: Data of 172 patients who underwent ultrasound-guided subacromial subdeltoid injection or glenohumeral joint injection were reviewed for preinjection point-of-care ultrasound findings, change in pain intensity at 2 mos from baseline, and use of care at 6 mos' postinjection...
August 1, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28761625/effects-of-redox-modulation-on-cell-proliferation-viability-and-migration-in-cultured-rat-and-human-tendon-progenitor-cells
#8
Yuk Wa Lee, Sai Chuen Fu, Man Yi Yeung, Chun Man Lawrence Lau, Kai Ming Chan, Leung Kim Hung
Tendon healing is slow and usually results in inferior fibrotic tissue formation. Recently, application of tendon derived stem cells (TDSCs) improved tendon healing in animal studies. In a chicken model, local injection of antioxidants reduced tendon adhesion after tendon injury. An in vitro study demonstrated that supplementation of H2O2 reduced tenogenic marker expression in TDSCs. These findings suggested that the possibility of TDSCs is involved in tendon healing and the cellular activities of TDSCs might be affected by oxidative stress of the local environment...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28760374/ropivacaine-alters-the-mechanical-properties-of-hamstring-tendons-in-vitro-controlled-mechanical-testing-of-tendons-from-living-donors
#9
Matthieu Ollivier, Jaafar Sbihi, Abderrahmane Sbihi, Martine Pithioux, Sebastien Parratte, Jean-Noel Argenson
OBJECTIVE: Intra-articular or peri-articular injection of ropivacaine (RI) is an element of current knee surgery practices. The goal of this study was to determine the effects of RI on the mechanical properties of hamstring tendons. METHODS: A tensile test to failure was performed on 120 hamstring tendon segments harvested during ACL reconstruction surgery in 120 patients. Two sets of tensile tests were done. The first evaluated the effect of RI itself on the mechanical properties of tendons: 30 samples were soaked for 1 hour in a 2% RI solution and compared to 30 samples soaked in a saline solution (control group)...
July 28, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28760125/comparison-of-the-effects-of-human-recombinant-epidermal-growth-factor-and-platelet-rich-plasma-on-healing-of-rabbit-patellar-tendon
#10
Baran Sarıkaya, Nihat Yumuşak, Akın Yigin, Serkan Sipahioğlu, Ünal Yavuz, Mehmet Akif Altay
OBJECTIVES: This study aims to compare the histological healing process and gene expression profile in tendon after the administration of human recombinant epidermal growth factor (hrEGF) and platelet-rich plasma (PRP). MATERIALS AND METHODS: A total of 24 mature New Zealand white rabbits (6-month-old; weight 2.5-3.0 kg) were used in the study. Patellar tendons of rabbits were tenotomized and then repaired. Rabbits were separated into three groups and repair areas were injected with 1 mL hrEGF in group 1 (n=9) and 1 mL PRP in group 2 (n=9)...
August 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/28744328/ultrasonographic-imaging-and-anti-inflammatory-therapy-of-muscle-and-tendon-injuries-using-polymer-nanoparticles
#11
Gi-Wook Kim, Changsun Kang, Young-Bin Oh, Myoung-Hwan Ko, Jeong-Hwan Seo, Dongwon Lee
Ultrasonography is a reliable diagnostic modality for muscle and tendon injuries, but it has been challenging to find right diagnosis of minor musculoskeletal injuries by conventional ultrasonographic imaging. A large amount of hydrogen peroxide (H2O2) are known to be generated during tissue damages such as mechanical injury and therefore H2O2 holds great potential as a diagnostic and therapeutic marker for mechanical injuries in the musculoskeletal system. We previously developed poly(vanillyl alcohol-co-oxalate) (PVAX), which rapidly scavenges H2O2 and exerts antioxidant and anti-inflammatory activity in H2O2-associated diseases...
2017: Theranostics
https://www.readbyqxmd.com/read/28727755/no-abatement-of-steroid-injections-for-tennis-elbow-in-australian-general-practice-a-15-year-observational-study-with-random-general-practitioner-sampling
#12
Bill Vicenzino, Helena Britt, Allan J Pollack, Michelle Hall, Kim L Bennell, David J Hunter
OBJECTIVE: Evaluate general practitioner (GP) management of tennis elbow (TE) in Australia. METHODS: Data about the management of TE by GPs from 2000 to 2015 were extracted from the Bettering the Evaluation of Care of Health program database. Patient and GP characteristics and encounter management data were classified by the International Classification of Primary Care, version 2, and reported using descriptive statistics with point estimates and 95% confidence intervals...
2017: PloS One
https://www.readbyqxmd.com/read/28718259/counterforce-orthosis-in-the-management-of-lateral-epicondylitis
#13
Daison Varghese Vellilappilly, Heroor Ravindranath Rai, Jaison Varghese, Vishnu Renjith
BACKGROUND: Lateral Epicondylitis (LE), is a condition characterized by the pain and tenderness over the lateral epicondyle of the humerus. LE is commonly seen among people who are involved in sports such as tennis and golf. Any activity that repeatedly overstrains the extensor carpi radialis brevis tendon can lead to LE. The management of lateral epicondylitis generally involves the use of counterforce orthosis. The aim of this review is to summarize the evidence regarding the effectiveness of counterforce orthoses on the clinical outcomes of patients with lateral epicondylitis...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28717615/outcomes-of-prolotherapy-for-intra-tendinous-achilles-tears-a-case-series
#14
Otto Chan, Ben Havard, Sarah Morton, Mel Pritchard, Nicola Maffulli, Tom Crisp, Nat Padhiar, Jeremy David Perry, John King, Dylan Morrissey
BACKGROUND: The intra-tendinous tear is a new pathology that is defined as a discontinuity of fibres situated entirely within the tendon. Prolotherapy involves injecting an irritant, such as hyperosmolar dextrose, to stimulate a tissue healing response and ultimately reduce pain. METHODS: 43 consecutive patients diagnosed with an intra-tendinous tear were included (27 males: 16 females, mean (SD) age 41 (11.3). Patients were injected with 0.4ml-1.5ml (mean 0.8ml) of 50% dextrose and 0...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28706816/endoscopic-stalk-resection-of-a-toe-ganglion-with-color-aided-visualization
#15
Takahisa Ogawa, Yasuhiro Seki, Shinichi Shirasawa
Ganglion cysts are common cystic lesions filled with a jelly-like substance and originate from a joint capsule or tendon sheath through a stalk. Ganglion cysts mostly occur in the hand region, for which surgical excision usually results in good outcomes. In contrast, toe ganglions are relatively rare, and surgical treatment is associated with a high recurrence rate because of unidentifiable ganglion stalks, requiring large skin incisions. We have treated toe ganglion cysts using endoscopy in the ganglion cyst by injecting methylene blue into the tendon sheath that connects to the ganglion stalk...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28698601/characteristics-of-sonography-in-a-rat-achilles-tendinopathy-model-possible-non-invasive-predictors-of-biomechanics
#16
Su-Ya Lee, Hsiao-Feng Chieh, Chien-Ju Lin, I-Ming Jou, Yung-Nien Sun, Li-Chieh Kuo, Po-Ting Wu, Fong-Chin Su
The purpose of this study was to investigate the dynamic changes of histopathology, biomechanical properties, echo intensity, and ultrasound features in a collagenase-induced tendinopathy model of rat Achilles tendons, and to examine the associations among biomechanical properties, echo intensity, and ultrasound features. Forty-two rats received an ultrasound-guided collagenase injection on their left Achilles tendons, and needle puncture on the right ones as the control. At four, eight, and twelve weeks post-injury, the tendons were examined via measurements of their biomechanical properties, histopathological and ultrasonographic characteristics...
July 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28689827/subacromial-corticosteroid-injections-transiently-decrease-suture-anchor-pullout-strength-biomechanical-studies-in-rats
#17
Oleg Dolkart, Ofir Chechik, Assaf Bivas, Tamar Brosh, Michael Drexler, Zachary Weinerman, Eran Maman
BACKGROUND: Arthroscopic rotator cuff (RC) repair incorporates suture anchors to secure torn RC tendons to the greater tuberosity (GT) bone. RC repair strength depends on the anchor-bone interface and on the quality of the GT. We evaluated the effect of single and multiple corticosteroid injections on the pullout strength of suture anchors. METHODS: Fifty rats were divided into those receiving saline solution injection (control group), a single methylprednisolone acetate (MTA) injection (MTA1 group), or 3 once-weekly MTA injections (MTA3 group)...
July 6, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28685665/effect-of-sodium-hyaluronate-carboxymethyl-cellulose-guardix-sol-on-retear-rate-and-postoperative-stiffness-in-arthroscopic-rotator-cuff-repair-patients-a-prospective-cohort-study
#18
Jeung Yeol Jeong, Pill Ku Chung, Jae Chul Yoo
PURPOSE: Hyaluronate-based anti-adhesive agents are expected to enhance rotator cuff healing; however, their effect on the incidence and extent of postoperative complications such as stiffness and retears has not been investigated. METHODS: From July 2012 to February 2013, 80 patients undergoing arthroscopic rotator cuff repair surgery were prospectively enrolled. Forty patients were assigned to the control group, while the other 40 were assigned to the injection group and received a Guardix-sol injection immediately after surgery...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28681515/accuracy-of-open-magnetic-resonance-imaging-for-guiding-injection-of-the-equine-deep-digital-flexor-tendon-within-the-hoof
#19
Lauren M Groom, Nathaniel A White, M Norris Adams, Jennifer G Barrett
Lesions of the distal deep digital flexor tendon (DDFT) are frequently diagnosed using MRI in horses with foot pain. Intralesional injection of biologic therapeutics shows promise in tendon healing; however, accurate injection of distal deep digital flexor tendon lesions within the hoof is difficult. The aim of this experimental study was to evaluate accuracy of a technique for injection of the deep digital flexor tendon within the hoof using MRI-guidance, which could be performed in standing patients. We hypothesized that injection of the distal deep digital flexor tendon within the hoof could be accurately guided using open low-field MRI to target either the lateral or medial lobe at a specific location...
July 6, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28680888/early-graft-tunnel-healing-after-anterior-cruciate-ligament-reconstruction-with-intratunnel-injection-of-bone-marrow-mesenchymal-stem-cells-and-vascular-endothelial-growth-factor
#20
Rosy Setiawati, Dwikora Novembri Utomo, Fedik Abdul Rantam, Nadia Nastassia Ifran, Nicolaas C Budhiparama
BACKGROUND: Bone marrow mesenchymal stem cells (BM-MSCs) are multipotent adult stem cells and have become an important source of cells for engineering tissue repair and cell therapy. Vascular endothelial growth factor (VEGF) promotes angiogenesis and contributes fibrous integration between tendon and bone during the early postoperative stage. Both MSCs and VEGF can stimulate cell proliferation, differentiation, and matrix deposition by enhancing angiogenesis and osteogenesis of the graft in the tunnel...
June 2017: Orthopaedic Journal of Sports Medicine
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