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https://www.readbyqxmd.com/read/29028593/genetic-variations-in-the-p11-tpa-bdnf-pathway-are-associated-with-post-stroke-depression
#1
Jinfeng Liang, Yingying Yue, Haitang Jiang, Deqin Geng, Jun Wang, Jianxin Lu, Shenghua Li, Kezhong Zhang, Aiqin Wu, Yonggui Yuan
BACKGROUND: The effects of BDNF on post stroke depression (PSD) may be influenced by genetic variations in intracellular signal transduction pathways, such as the p11/tPA/BDNF pathway. In this study, we aimed to determine the association of polymorphisms in candidate genes of the gene transduction pathway with PSD, as well as the effects of the interactions between genes in our Chinese sample. METHODS: Two-hundred-fifty-four Chinese samples with acute ischaemic stroke included 122 PSD patients and 132 nonPSD patients...
September 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29028522/an-examination-of-sex-differences-in-neurocognition-and-social-cognition-in-first-episode-psychosis
#2
Haylee Danaher, Kelly Allott, Eóin Killackey, Robert Hester, Sue Cotton
Due to the dearth and conflicting findings of previous research, it is unclear whether males and females with first-episode psychosis (FEP) differ in their neurocognitive and social cognitive abilities. The aims of the current study were to investigate whether: (i) there are sex differences in neurocognition and social cognition among young people with FEP; and (ii) they resemble those observed in age-matched healthy controls. The current study involved secondary analysis of data from a previous study in which a large neurocognitive and social cognitive battery was administered to 146 individuals with FEP and 46 healthy controls aged 15-25 years...
September 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29028156/genetic-background-effects-in-neuroligin-3-mutant-mice-minimal-behavioral-abnormalities-on-c57-background
#3
Thomas C Jaramillo, Christine Ochoa Escamilla, Shunan Liu, Lauren Peca, Shari G Birnbaum, Craig M Powell
Neuroligin-3 (NLGN3) is a postsynaptic cell adhesion protein that interacts with presynaptic ligands including neurexin-1 (NRXN1) [Ichtchenko et al., Journal of Biological Chemistry, 271, 2676-2682, 1996]. Mice harboring a mutation in the NLGN3 gene (NL3R451C) mimicking a mutation found in two brothers with autism spectrum disorder (ASD) were previously generated and behaviorally phenotyped for autism-related behaviors. In these NL3R451C mice generated and tested on a hybrid C57BL6J/129S2/SvPasCrl background, we observed enhanced spatial memory and reduced social interaction [Tabuchi et al...
October 13, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29027815/l-carnosine-as-an-adjunctive-therapy-to-risperidone-in-children-with-autistic-disorder-a-randomized-double-blind-placebo-controlled-trial
#4
Reihaneh Hajizadeh-Zaker, Alireza Ghajar, Bita Mesgarpour, Mohsen Afarideh, Mohammad-Reza Mohammadi, Shahin Akhondzadeh
OBJECTIVES: This study aimed at investigating the efficacy and tolerability of l-carnosine as an add-on to risperidone in the management of children with autism. METHODS: This was a 10-week, randomized, double-blind, placebo-controlled study. Seventy drug-free children aged 4-12 years old with a diagnosis of autism spectrum disorder (ASD), according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition. (DSM-5) who had an Aberrant Behavior Checklist-Community (ABC-C) scale irritability subscale score of ≥12, entered the study...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29027649/sex-specific-effects-of-combined-exposure-to-chemical-and-non-chemical-stressors-on-neuroendocrine-development-a-review-of-recent-findings-and-putative-mechanisms
#5
REVIEW
Whitney J Cowell, Rosalind J Wright
PURPOSE OF REVIEW: Environmental toxicants and psychosocial stressors share many biological substrates and influence overlapping physiological pathways. Increasing evidence indicates stress-induced changes to the maternal milieu may prime rapidly developing physiological systems for disruption by concurrent or subsequent exposure to environmental chemicals. In this review, we highlight putative mechanisms underlying sex-specific susceptibility of the developing neuroendocrine system to the joint effects of stress or stress correlates and environmental toxicants (bisphenol A, alcohol, phthalates, lead, chlorpyrifos, and traffic-related air pollution)...
October 13, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/29027602/combining-risk-communication-strategies-to-simultaneously-convey-the-risks-of-four-diseases-associated-with-physical-inactivity-to-socio-demographically-diverse-populations
#6
Eva Janssen, Robert A C Ruiter, Erika A Waters
A single risk factor can increase the risk of developing multiple diseases, but most risk communication research has been conducted in the context of a single disease. We explored which combination of three recommended risk communication strategies is most effective in simultaneously conveying risk estimates of four diseases associated with physical inactivity: colon cancer, stroke, diabetes, and heart disease. Participants (N = 1161, 50% no college experience, 50% racial/ethnic minority) were shown hypothetical risk estimates for each of the four diseases...
October 13, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29026880/adaptive-social-strategies-in-a-solitary-carnivore
#7
L Mark Elbroch, Michael Levy, Mark Lubell, Howard Quigley, Anthony Caragiulo
Cost-benefit trade-offs for individuals participating in social behaviors are the basis for current theories on the evolution of social behaviors and societies. However, research on social strategies has largely ignored solitary animals, in which we assume that rare interactions are explained by courtship or territoriality or, in special circumstances, resource distributions or kinship. We used directed network analysis of conspecific tolerance at food sources to provide evidence that a solitary carnivore, the puma (Puma concolor), exhibited adaptive social strategies similar to more social animals...
October 2017: Science Advances
https://www.readbyqxmd.com/read/29026510/a-novel-system-for-tracking-social-preference-dynamics-in-mice-reveals-sex-and-strain-specific-characteristics
#8
Shai Netser, Shani Haskal, Hen Magalnik, Shlomo Wagner
BACKGROUND: Deciphering the biological mechanisms underlying social behavior in animal models requires standard behavioral paradigms that can be unbiasedly employed in an observer- and laboratory-independent manner. During the past decade, the three-chamber test has become such a standard paradigm used to evaluate social preference (sociability) and social novelty preference in mice. This test suffers from several caveats, including its reliance on spatial navigation skills and negligence of behavioral dynamics...
2017: Molecular Autism
https://www.readbyqxmd.com/read/29026455/interactive-visualization-of-public-health-indicators-to-support-policymaking-an-exploratory-study
#9
Moutasem Zakkar, Kamran Sedig
The purpose of this study is to examine the use of interactive visualizations to represent data/information related to social determinants of health and public health indicators, and to investigate the benefits of such visualizations for health policymaking. METHODS: The study developed a prototype for an online interactive visualization tool that represents the social determinants of health. The study participants explored and used the tool. The tool was evaluated using the informal user experience evaluation method...
2017: Online Journal of Public Health Informatics
https://www.readbyqxmd.com/read/29024875/social-networking-online-to-recover-from-opioid-use-disorder-a-study-of-community-interactions
#10
Alexandra R D'Agostino, Allison R Optican, Shaina J Sowles, Melissa J Krauss, Kiriam Escobar Lee, Patricia A Cavazos-Rehg
BACKGROUND: Social media has increasingly become a venue for health discourse and support, particularly for vulnerable individuals. This study examines user-generated content of an online Reddit community targeting individuals recovering from opiate addiction. METHODS: 100 Reddit posts and their comments were collected from the online community on August 19, 2016. Posts were qualitatively coded for opioid use disorder (OUD) criteria as outlined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), as well as other common themes...
October 5, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29024640/sociovirology-conflict-cooperation-and-communication-among-viruses
#11
Samuel L Díaz-Muñoz, Rafael Sanjuán, Stuart West
Viruses are involved in various interactions both within and between infected cells. Social evolution theory offers a conceptual framework for how virus-virus interactions, ranging from conflict to cooperation, have evolved. A critical examination of these interactions could expand our understanding of viruses and be exploited for epidemiological and medical interventions.
October 11, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/29024193/interbrain-phase-synchronization-during-turn-taking-verbal-interaction-a-hyperscanning-study-using-simultaneous-eeg-meg
#12
Sangtae Ahn, Hohyun Cho, Moonyoung Kwon, Kiwoong Kim, Hyukchan Kwon, Bong Soo Kim, Won Seok Chang, Jin Woo Chang, Sung Chan Jun
Recently, neurophysiological findings about social interaction have been investigated widely, and hardware has been developed that can measure multiple subjects' brain activities simultaneously. These hyperscanning studies have enabled us to discover new and important evidences of interbrain interactions. Yet, very little is known about verbal interaction without any visual input. Therefore, we conducted a new hyperscanning study based on verbal, interbrain turn-taking interaction using simultaneous EEG/MEG, which measures rapidly changing brain activities...
October 11, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29024074/comparison-of-subjective-wellbeing-in-substance-users-and-the-parents-or-partners-of-substance-users
#13
Robert J Tait
INTRODUCTION AND AIMS: There is growing interest in the impact of substance use on both the individual consumer's subjective wellbeing (SWB) and the reduced SWB of those closely connected to him or her. The study aimed to compare SWB among substance users ('consumers') and the parents or partners affected by another's substance use, and to evaluate the effect of counselling on changed SWB to 6 months. DESIGN AND METHODS: The study used longitudinal data from a not-for-profit treatment service based in Perth, Australia...
October 12, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/29024009/is-kidney-transplantation-safe-after-careful-selection-of-the-recipients-with-a-history-of-psychotic-disorder
#14
Miklos Z Molnar
The prevalence of both bipolar disorder and schizophrenia is around 1-4% in the general population and represents a relative contraindication for kidney transplantation. There are several reasons for this, including concerns in relation to relapse of psychiatric illness, medication and other post-transplant treatment non-adherence, inadequate social support, emotional and cognitive capability, and potential drug interactions between psychotropic and immunosuppressant medications. Only a small proportion of recipients with psychotic disorder has eventually been transplanted...
October 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29023900/durability-and-flexibility-of-chimpanzee-grooming-patterns-during-a-period-of-dominance-instability
#15
Nicola F Koyama, Kirsty Ronkainen, Filippo Aureli
Growing evidence from studies on primates and other taxa has shown that the maintenance of long-term affiliative patterns influences fitness. Thus, understanding how individuals regulate social interactions in response to environmental and social factors contributes to our understanding of the evolutionary basis of sociality. We investigated the durability of affiliation patterns in chimpanzees across three 3-month periods of varying social uncertainty depending on the degree of stability in the male hierarchy, with a 2-year gap between each period...
October 12, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29023568/demonstrating-the-reliability-of-transdiagnostic-mhealth-routine-outcome-monitoring-in-mental-health-services-using-experience-sampling-technology
#16
Simone J W Verhagen, Juliënne A Berben, Carsten Leue, Anne Marsman, Philippe A E G Delespaul, Jim van Os, Richel Lousberg
BACKGROUND: Routine Outcome Monitoring (ROM) should provide a dynamic, within-treatment forward feedback loop to guide individual treatment decisions across diagnostic categories. It has been suggested that the Experience Sampling Method (ESM), capturing the film of daily life adaptive processes, offers a flexible, personalised and transdiagnostic feedback system for monitoring and adapting treatment strategies. This is the first study that uses an ESM application (the PsyMate™) as a routine mobile-ROM (mROM) tool in an ambulatory mental health setting...
2017: PloS One
https://www.readbyqxmd.com/read/29023545/territorial-choruses-of-giant-otter-groups-pteronura-brasiliensis-encode-information-on-group-identity
#17
Christina A S Mumm, Mirjam Knörnschild
Group living animals often engage in corporate territorial defence. Territorial group vocalizations can provide information about group identity, size and composition. Neighbouring groups may use this information to avoid unfavourable direct conflicts. Giant otters are highly social and territorial animals with an elaborate vocal repertoire. They produce long-range screams when they are alert or excited, i.e. in an alarm, isolation or begging context. Long-range screams are not only produced by one individual at a time ('single screams') but also by multiple group members simultaneously, resulting in a highly conspicuous 'group chorus'...
2017: PloS One
https://www.readbyqxmd.com/read/29023293/form-function-and-esthetics-in-prosthetically-rehabilitated-maxillary-defects
#18
Manish Mittal, Rohit Sharma, Ashish Kalra, Parvinder Sharma
PURPOSE: Patients with maxillofacial defects secondary to the removal of benign and malignant pathologies of midface have a profound impact on quality of life. The aim of this study was to collect and analyze the data pertaining to 4 designs of obturator by assessment of the patient with obturator functioning scale (OFS) MATERIALS AND METHODS:: This retrospective analysis included all the patients who underwent prosthetic rehabilitation of maxillary defects using 4 different types (conventional, cast partial, hollow bulb, and magnet retained) of obturators from 2009 to 2016 with minimum 1 year of follow up...
October 11, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29023134/a-systematic-review-of-correlates-of-depression-among-older-chinese-and-korean-immigrants-what-we-know-and-do-not-know
#19
Man Guo, Meredith Stensland
OBJECTIVES: Guided by the stress and coping theory, this study provides a systematic review of existing research on acculutration, family support, and social support related correlates of depression among older Chinese and Korean immigrants in the United States. METHOD: A comprehensive literature search was conducted in CINAHL Plus, Abstracts in Social Gerontology, AgeLine, Social Work Abstracts, PubMed, PsychINFO, and Social Science Citation Index databases to identify relevant articles that presented multivariate analysis results...
October 12, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29022853/destination-memory-in-social-interaction-better-memory-for-older-than-for-younger-destinations-in-normal-aging
#20
Mohamad El Haj, Stéphane Raffard, Luciano Fasotti, Philippe Allain
Destination memory, a memory component allowing the attribution of information to its appropriate receiver (e.g., to whom did I lend my pen?), is compromised in normal aging. The present paper investigated whether older adults might show better memory for older destinations than for younger destinations. This hypothesis is based on empirical research showing better memory for older faces than for younger faces in older adults. Forty-one older adults and 44 younger adults were asked to tell proverbs to older and younger destinations (i...
October 12, 2017: Memory
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