Mohmmad Imran, Shriya Singh, Mohammad Naiyaz Ahmad, Pradip Malik, Atri Mukhopadhyay, Karan Singh Yadav, Umesh D Gupta, Madhav N Mugale, Kalyan Mitra, Kishore K Srivastava, Sidharth Chopra, Serge Mignani, Evgeny Apartsin, Jean-Pierre Majoral, Arunava Dasgupta
Mycobacterium tuberculosis (Mtb), causative agent of tuberculosis (TB) and non-tubercular mycobacterial (NTM) pathogens such as Mycobacterium abscessus are one of the most critical concerns worldwide due to increased drug-resistance resulting in increased morbidity and mortality. Therefore, focusing on developing novel therapeutics to minimize the treatment period and reducing the burden of drug-resistant Mtb and NTM infections are an urgent and pressing need. In our previous study, we identified anti-mycobacterial activity of orally bioavailable, non-cytotoxic, polycationic phosphorus dendrimer 2G0 against Mtb...
March 6, 2024: Biomedicine & Pharmacotherapy