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https://www.readbyqxmd.com/read/28548247/market-for-artemether-lumefantrine-to-treat-childhood-malaria-in-a-district-of-southern-mozambique
#1
Sergi Alonso, Khátia Munguambe, Elisa Sicuri
Malaria is one of the leading causes of death in sub-Saharan Africa. Artemisinin-based combination therapies are used as first-line treatment drugs, but their market is far from competitive. Market failures include limited availability, low quality, lack of information, and high costs of access. We estimated the theoretical demand for one of the most common artemisinin-based combination therapies, artemether-lumefantrine (AL), and its determinants among caregivers of children with malaria seeking care at public health facilities, thus, entitled to receive drugs for free, in southern Mozambique (year 2012)...
May 26, 2017: Health Economics
https://www.readbyqxmd.com/read/28545595/modelling-the-influence-of-climate-on-malaria-occurrence-in-chimoio-municipality-mozambique
#2
João Luís Ferrão, Jorge M Mendes, Marco Painho
BACKGROUND: Mozambique was recently ranked fifth in the African continent for the number of cases of malaria. In Chimoio municipality cases of malaria are increasing annually, contrary to the decreasing trend in Africa. As malaria transmission is influenced to a large extent by climatic conditions, modelling this relationship can provide useful insights for designing precision health measures for malaria control. There is a scarcity of information on the association between climatic variability and malaria transmission risk in Mozambique in general, and in Chimoio in particular...
May 25, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28545540/assessment-of-coverage-of-preventive-treatment-and-insecticide-treated-mosquito-nets-in-pregnant-women-attending-antenatal-care-services-in-11-districts-in-mozambique-in-2011-the-critical-role-of-supply-chain
#3
Cristolde Salomão, Jahit Sacarlal, Eduardo Samo Gudo
BACKGROUND: Malaria during pregnancy is associated with poor maternal and pregnancy outcome and the World Health Organization recommends the administration of intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) and distribution of insecticide-treated mosquito nets (ITNs) to all pregnant women attending antenatal care (ANC) services. This study was conducted with the aim to assess the uptake of IPTp and ITNs in pregnant women attending ANC services and correlate with ANC attendance and frequency of stock-outs in 22 health facilities Mozambique...
May 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28539190/water-sanitation-and-hygiene-in-schools-status-and-implications-of-low-coverage-in-ethiopia-kenya-mozambique-rwanda-uganda-and-zambia
#4
Camille Morgan, Michael Bowling, Jamie Bartram, Georgia Lyn Kayser
Adequate access to water, sanitation, and hygiene (WaSH) in schools impacts health, educational outcomes, and gender disparities. Little multi-country research has been published on WaSH in rural schools in Sub-Saharan Africa. In this multi-national cross-sectional WaSH study, we document WaSH access, continuity, quality, quantity, and reliability in 2270 schools that were randomly sampled in rural regions of six Sub-Saharan African countries: Ethiopia, Kenya, Mozambique, Rwanda, Uganda, and Zambia. Data collection included: school WaSH surveys containing internationally established WaSH indicators, direct observation, and field- and laboratory-based microbiological water quality testing...
April 19, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28535809/safety-and-tolerability-of-adjunctive-rosiglitazone-treatment-for-children-with-uncomplicated-malaria
#5
Rosauro Varo, Valerie M Crowley, Antonio Sitoe, Lola Madrid, Lena Serghides, Rubao Bila, Helio Mucavele, Alfredo Mayor, Quique Bassat, Kevin C Kain
BACKGROUND: Despite the widespread use and availability of rapidly acting anti-malarials, the fatality rate of severe malaria in sub-Saharan Africa remains high. Adjunctive therapies that target the host response to malaria infection may further decrease mortality over that of anti-malarial agents alone. Peroxisome proliferator-activated receptor-gamma agonists (e.g. rosiglitazone) have been shown to act on several pathways implicated in the pathogenesis of severe malaria and may improve clinical outcome as an adjunctive intervention...
May 23, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28534868/a-new-long-term-daily-satellite-based-rainfall-dataset-for-operational-monitoring-in-africa
#6
Ross I Maidment, David Grimes, Emily Black, Elena Tarnavsky, Matthew Young, Helen Greatrex, Richard P Allan, Thorwald Stein, Edson Nkonde, Samuel Senkunda, Edgar Misael Uribe Alcántara
Rainfall information is essential for many applications in developing countries, and yet, continually updated information at fine temporal and spatial scales is lacking. In Africa, rainfall monitoring is particularly important given the close relationship between climate and livelihoods. To address this information gap, this paper describes two versions (v2.0 and v3.0) of the TAMSAT daily rainfall dataset based on high-resolution thermal-infrared observations, available from 1983 to the present. The datasets are based on the disaggregation of 10-day (v2...
May 23, 2017: Scientific Data
https://www.readbyqxmd.com/read/28532410/malaria-mortality-characterization-and-the-relationship-between-malaria-mortality-and-climate-in-chimoio-mozambique
#7
João Luís Ferrão, Jorge M Mendes, Marco Painho, Sara Zacarias
BACKGROUND: The United Nation's sustainable development goal for 2030 is to eradicate the global malaria epidemic, primarily as the disease continues to be one of the major concerns for public health in sub-Saharan Africa. In 2015, the region accounted for 90% of malaria deaths. Mozambique recorded a malaria mortality rate of 42.75 (per 100,000). In Chimoio, Mozambique's fifth largest city, malaria is the fourth leading cause of death (9.4%). Few data on malaria mortality exists in Mozambique, particularly in relation to Chimoio...
May 22, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28527534/austerity-and-the-sector-wide-approach-to-health-the-mozambique-experience
#8
James Pfeiffer, Sarah Gimbel, Baltazar Chilundo, Stephen Gloyd, Rachel Chapman, Kenneth Sherr
Fiscal austerity policies imposed by the IMF have reduced investments in social services, leaving post-independence nations like Mozambique struggling to recover from civil war and high disease burden. By 2000, a sector-wide approach (SWAp) was promoted to maximize aid effectiveness. 'Like-minded' bilateral donors, from Europe and Canada, promoted a unified approach to health sector support focusing on joint planning, common basket funding, and streamlined monitoring and evaluation to improve sector coordination, amplify country ownership, and build sustainable health systems...
May 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28522992/molecular-characterization-of-community-acquired-staphylococcus-aureus-bacteremia-in-young-children-in-southern-mozambique-2001-2009
#9
Delfino Vubil, Marcelino Garrine, Ulla Ruffing, Sozinho Acácio, Betuel Sigaúque, Pedro L Alonso, Lutz von Müller, Mathias Herrmann, Inácio Mandomando
Background: The emergence of community-acquired Staphylococcus aureus infections is increasingly recognized as life threating problem worldwide. In Manhiça district, southern Mozambique, S. aureus is the leading cause of community-acquired bacteremia in neonates. Methods: Eighty-four S. aureus isolates from children less than 5 years admitted to Manhiça District Hospital from 2001 to 2009 were randomly selected and genetically characterized by DNA microarray and spa typing. Antimicrobial susceptibility was determined by VITEK 2...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28515729/growth-and-yield-responses-of-cowpea-to-inoculation-and-phosphorus-fertilization-in-different-environments
#10
Stephen Kyei-Boahen, Canon E N Savala, David Chikoye, Robert Abaidoo
Cowpea (Vigna unguiculata) is a major source of dietary protein and essential component of the cropping systems in semi-arid regions of Sub-Saharan Africa. However, yields are very low due to lack of improved cultivars, poor management practices, and limited inputs use. The objectives of this study were to assess the effects of rhizobia inoculant and P on nodulation, N accumulation and yield of two cowpea cultivars in Mozambique. Field study was conducted in three contrasting environments during the 2013/2014 and 2014/2015 seasons using randomized complete block design with four replications and four treatments...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28498315/factors-associated-with-stunting-among-children-aged-0-to-59-months-from-the-central-region-of-mozambique
#11
Loida M García Cruz, Gloria González Azpeitia, Desiderio Reyes Súarez, Alfredo Santana Rodríguez, Juan Francisco Loro Ferrer, Lluis Serra-Majem
The objective of this study was to identify the major socio-demographic, health, and environmental determinants of stunting among children aged 0-59 months from the Tete province (Mozambique) and offering useful information for future healthcare strategies and interventions. A case-control study was conducted among 282 (162 boys; 120 girls) children under five years of age from the central region of Mozambique between 1 May and 3 June 2014. Children with stunting (HAZ < -2 SD according to the WHO Child Growth Standards in 2006) were considered as cases and those who had a Z-score < -2 SD were considered as controls...
May 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28486956/the-comprehensive-communicate-to-vaccinate-taxonomy-of-communication-interventions-for-childhood-vaccination-in-routine-and-campaign-contexts
#12
Jessica Kaufman, Heather Ames, Xavier Bosch-Capblanch, Yuri Cartier, Julie Cliff, Claire Glenton, Simon Lewin, Artur Manuel Muloliwa, Afiong Oku, Angela Oyo-Ita, Gabriel Rada, Sophie Hill
BACKGROUND: Communication can be used to generate demand for vaccination or address vaccine hesitancy, and is crucial to successful childhood vaccination programmes. Research efforts have primarily focused on communication for routine vaccination. However, vaccination campaigns, particularly in low- or middle-income countries (LMICs), also use communication in diverse ways. Without a comprehensive framework integrating communication interventions from routine and campaign contexts, it is not possible to conceptualise the full range of possible vaccination communication interventions...
May 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28481996/drivers-of-health-system-strengthening-learning-from-implementation-of-maternal-and-child-health-programmes-in-mozambique-nepal-and-rwanda
#13
Fiona Samuels, Ana B Amaya, Dina Balabanova
There is a growing understanding that strong health systems are crucial to sustain progress. Health systems, however, are complex and much of their success depends on factors operating at different levels and outside the health system, including broader governance and political commitment to health and social development priorities. Recognizing these complexities, this article offers a pragmatic approach to exploring the drivers of progress in maternal and child health in Mozambique, Nepal and Rwanda. To do this, the article builds on a semi-systematic literature review and case study findings, designed and analysed using a multi-level framework...
May 7, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28474290/serological-evidence-of-avian-encephalomyelitis-virus-and-pasteurella-multocida-infections-in-free-range-indigenous-chickens-in-southern-mozambique
#14
Paula Taunde, Palmira Timbe, Ana Felicidade Lucas, Cesaltina Tchamo, Abel Chilundo, Filomena Dos Anjos, Rosa Costa, Custodio Gabriel Bila
A total of 398 serum samples from free-range indigenous chickens originating from four villages in Southern Mozambique were tested for the presence of avian encephalomyelitis virus (AEV) and Pasteurella multocida (PM) antibodies through commercial enzyme-linked immunosorbent assay (ELISA) kits. AEV and PM antibodies were detected in all villages surveyed. The proportion of positive samples was very high: 59.5% (95% confidence interval (CI) 51.7-67.7%) for AEV and 71.5% (95% CI 67.7-77.3%) for PM. Our findings revealed that these pathogens are widespread among free-range indigenous chickens in the studied villages and may represent a threat in the transmission of AEV and PM to wild, broiler or layer chickens in the region...
May 4, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28468533/willingness-to-use-short-term-oral-pre-exposure-prophylaxis-prep-by-migrant-miners-and-female-partners-of-migrant-miners-in-mozambique
#15
Joana Falcao, Laurence Ahoua, Allison Zerbe, Pietro di Mattei, Rachel Baggaley, Victor Chivurre, Prince Mulondo, Isaias Ramiro, Shona Dalal, Fernando Morales, Kevin O'Reilly, Wafaa El-Sadr
Migrant miners from Mozambique who work in South Africa and their partners are at substantial risk for HIV infection. We conducted a cross-sectional study to assess the willingness of migrant miners and female partners of miners to take short-term pre-exposure prophylaxis (PrEP) for prevention of HIV acquisition. The study was conducted in Gaza Province, Mozambique, between September and October 2015. A total of 131 male miners and female partners of male miners completed a questionnaire. Subsequently, 48 in-depth interviews among male miners and female partners of miners and 3 focus-group discussions (6 participants each) among female partners of miners were conducted...
May 4, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28465550/in-vivo-efficacy-of-chloroquine-to-clear-asymptomatic-infections-in-mozambican-adults-a-randomized-placebo-controlled-trial-with-implications-for-elimination-strategies
#16
Beatriz Galatas, Lidia Nhamussua, Baltazar Candrinho, Lurdes Mabote, Pau Cisteró, Himanshu Gupta, Regina Rabinovich, Clara Menéndez, Eusebio Macete, Francisco Saute, Alfredo Mayor, Pedro Alonso, Quique Bassat, Pedro Aide
Recent reports regarding the re-emergence of parasite sensitivity to chloroquine call for a new consideration of this drug as an interesting complementary tool in malaria elimination efforts, given its good safety profile and long half-life. A randomized (2:1), single-blind, placebo-controlled trial was conducted in Manhiça, Mozambique, to assess the in-vivo efficacy of chloroquine to clear plasmodium falciparum (Pf) asymptomatic infections. Primary study endpoint was the rate of adequate and parasitological response (ACPR) to therapy on day 28 (PCR-corrected)...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28464850/the-impact-of-facility-audits-evaluation-reports-and-incentives-on-motivation-and-supply-management-among-family-planning-service-providers-an-interventional-study-in-two-districts-in-maputo-province-mozambique
#17
Heleen Vermandere, Anna Galle, Sally Griffin, Málica de Melo, Lino Machaieie, Dirk Van Braeckel, Olivier Degomme
BACKRGOUND: Good progress is being made towards universal access to contraceptives, however stock-outs still jeopardize progress. A seldom considered but important building block in optimizing supply management is the degree to which health workers feel motivated and responsible for monitoring supply. We explored how and to what extent motivation can be improved, and the impact this can have on avoiding stock-outs. METHODS: Fifteen health facilities in Maputo Province, Mozambique, were divided into 3 groups (2 intervention groups and 1 control), and 10 monthly audits were implemented in each of these 15 facilities to collect data through examination of stock cards and stock-counts of 6 contraceptives...
May 2, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28464825/continuous-determination-of-blood-glucose-in-children-admitted-with-malaria-in-a-rural-hospital-in-mozambique
#18
Lola Madrid, Antonio Sitoe, Rosauro Varo, Tacilta Nhampossa, Miguel Lanaspa, Abel Nhama, Sozinho Acácio, Isolina Riaño, Aina Casellas, Quique Bassat
BACKGROUND: Hypoglycaemia is a frequent complication among admitted children, particularly in malaria-endemic areas. This study aimed to estimate the occurrence of hypoglycaemia not only upon admission but throughout the first 72 h of hospitalization in children admitted with malaria. METHODS: A simple pilot study to continuously monitor glycaemia in children aged 0-10 years, admitted with malaria in a rural hospital was conducted in Southern Mozambique by inserting continuous glucose monitors (CGMs) in subcutaneous tissue of the abdominal area, producing glycaemia readings every 5 min...
May 2, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28462745/the-efficiency-of-the-local-health-systems-investigating-the-roles-of-health-administrations-and-health-care-providers
#19
Laura Anselmi, Mylène Lagarde, Kara Hanson
The analysis of efficiency in health care has largely focussed either on individual health care providers, or on sub-national health systems conceived as a unique decision-making unit. However, in hierarchically organized national health services, two separate entities are responsible for turning financial resources into services at the local level: health administrations and health care providers. Their separate roles and the one of health administrations in particular have not been explicitly considered in efficiency analysis...
May 2, 2017: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/28452653/the-medical-education-partnership-initiative-mepi-a-collaborative-paradigm-for-institutional-and-human-resources-capacity-building-between-high-and-low-and-middle-income-countries-the-mozambique-experience
#20
Emília Virgínia Noormahomed, Carla Carrilho, Mamudo Ismail, Sérgio Noormahomed, Alcido Nguenha, Constance A Benson, Ana Olga Mocumbi, Robert T Schooley
BACKGROUND: Collaborations among researchers based in lower and middle income countries (LMICs) and high income countries (HICs) have made major discoveries related to diseases disproportionately affecting LMICs and have been vital to the development of research communities in LMICs. Such collaborations have generally been scientifically and structurally driven by HICs. OBJECTIVES: In this report we outline a paradigm shift in collaboration, exemplified by the Medical Education Partnership Initiative (MEPI), in which the formulation of priorities and administrative infrastructure reside in the LMIC...
2017: Global Health Action
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