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https://www.readbyqxmd.com/read/28443616/effects-of-extended-cannabis-abstinence-on-cognitive-outcomes-in-cannabis-dependent-patients-with-schizophrenia-versus-non-psychiatric-controls
#1
Rachel A Rabin, Mera S Barr, Michelle S Goodman, Yarissa Herman, Konstantine K Zakzanis, Stephen J Kish, Michael Kiang, Gary Remington, Tony P George
Cross-sectional studies of the effects of cannabis on cognition in schizophrenia have produced mixed results. Heavy and persistent cannabis use in schizophrenia is a common clinical problem, and effects of controlled abstinence from cannabis in these patients have not been carefully evaluated. The present study sought to determine the effects of cannabis abstinence on cognition in patients with schizophrenia and co-occurring cannabis dependence. We utilized a 28-day cannabis abstinence paradigm to investigate the state-dependent effects of cannabis on select cognitive outcomes in cannabis dependent patients with schizophrenia and non-psychiatric controls...
April 26, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28441050/comparison-of-platelet-function-and-viscoelastic-test-results-between-healthy-dogs-and-dogs-with-naturally-occurring-chronic-kidney-disease
#2
Alicia Dudley, Julie K Byron, Mary Jo Burkhard, Emma Warry, Julien Guillaumin
OBJECTIVE To compare platelet function and viscoelastic test results between healthy dogs and dogs with chronic kidney disease (CKD) to assess whether dogs with CKD have platelet dysfunction and altered blood coagulation. ANIMALS 10 healthy control dogs and 11 dogs with naturally occurring CKD. PROCEDURES Blood and urine were collected once from each dog for a CBC, serum biochemical analysis, urinalysis, and determination of the urine protein-to-creatinine ratio, prothrombin time, activated partial thromboplastin time, plasma fibrinogen concentration, and antithrombin activity...
May 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28440101/behind-the-scenes-in-urinalysis-to-report-or-not-to-report
#3
Samuel Azuz, Jan Berg Gertsen, Sofie Skovmand Rasmussen, Christian Salgaard Jensen, Erik Filip Jansåker, David Fuglsang-Damgaard
No abstract text is available yet for this article.
April 25, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28435765/chronic-nephropathy-from-dietary-hyperoxaluria-sustained-improvement-of-renal-function-after-dietary-intervention
#4
Yijuan Sun, Bruce L Horowitz, Karen S Servilla, Joanna R Fair, Darlene Vigil, Kavitha Ganta, Larry Massie, Antonios H Tzamaloukas
A 56-year-old man with stable chronic kidney disease (CKD) for two years following a single episode of calcium oxalate urolithiasis developed progressive elevation of his serum creatinine concentration. Urinalysis revealed pyuria and white cell casts, a few red blood cells, minimal proteinuria, and no crystals. Urine culture was sterile. Gallium scintigraphy was consistent with interstitial nephritis. Proton pump inhibitor intake was discontinued, and a short course of oral corticosteroids was initiated. Percutaneous kidney biopsy, performed because of the continued deterioration of renal function to a minimum estimated glomerular filtration rate (eGFR) value of 15 mL/min per 1...
March 20, 2017: Curēus
https://www.readbyqxmd.com/read/28435196/hemato-biochemical-alterations-and-urinalysis-in-dogs-suffering-from-benign-prostatic-hyperplasia
#5
M R Das, R C Patra, R K Das, P K Rath, B P Mishra
AIM: The study was designed to evaluate the hemato-biochemical alterations, urinalysis along with histomorphological and histological changes of prostate glands in dogs affected with benign prostatic hyperplasia (BPH) in and around Bhubaneswar, Odisha, India. MATERIALS AND METHODS: In toto, 445 dogs presented to the Teaching Veterinary Clinical Complex of the College of Veterinary Sciences and Animal Husbandry, one Government Veterinary Hospital and two pet clinics in and around Bhubaneswar screened for the presence of BPH...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28428020/repeated-sub-chronic-oral-toxicity-study-of-xylooligosaccharides-xos-in-dogs
#6
Yonglin Gao, Yunzhi Wang, Yanshen Li, Rui Han, Chunmei Li, Lin Xiao, Susan Cho, Yukui Ma, Chao Fang, Albert W Lee
In this study, Beagle dogs were administered xylooligosaccharide (XOS, CAS # 87099-0) at doses of 0, 1250, 2500, and 5000 mg/kg/day by oral gavage for 26 weeks. A 4-week recovery period was added to observe delayed or reversible toxicity. Measurements included body weight, food consumption, clinical observations, temperature, electrocardiogram (ECG), urinalysis, blood chemistry, hematology, organ weight, gross necropsy, and histopathological examination. Except for transient diarrhea or vomiting, no treatment-related adverse effects were noted...
April 17, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28424831/-recurrent-and-catheter-associated-urinary-tract-infections-prophylaxis-and-prevention
#7
H Piechota
Urinay tract infection (UTI) as one of the most frequent bacterial infections in humans is of utmost relevance. Because of the rising prevalence of antimicrobial resistance, urinalysis should always include urine culture and a resistogram in order to avoid an unspecific selection and overuse of antibiotics. Prevention of recurrent UTI must first of all rule out predisposing uropathogenic conditions. Nowadays, a great variety of drugs, behavioral, and supportive treatment options can effectively minimize UTI recurrence...
April 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28420507/asymptomatic-pyuria-in-pregnant-women-during-the-first-trimester-is-associated-with-an-increased-risk-of-adverse-obstetrical-outcomes
#8
Yun-Ju Lai, Te-Yao Hsu, Kuo-Chung Lan, Hao Lin, Chia-Yu Ou, Hung-Chun Fu, Ching-Chang Tsai
OBJECTIVE: Urinalysis is included in the prenatal examination in the first trimester in Taiwan, in contrast to Western countries. We aimed to investigate whether asymptomatic pyuria as detected by urinalysis was associated with adverse perinatal outcomes. MATERIALS AND METHODS: A total of 1187 singleton pregnant women who received prenatal care at Kaohsiung Chang Gung Memorial Hospital between January 2012 and December 2013 were included for retrospective analysis...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28418451/cost-effectiveness-of-common-diagnostic-approaches-for-evaluation-of-asymptomatic-microscopic-hematuria
#9
Joshua A Halpern, Bilal Chughtai, Hassan Ghomrawi
Importance: Asymptomatic microscopic hematuria (AMH) is highly prevalent and may signal occult genitourinary (GU) malignant abnormality. Common diagnostic approaches differ in their costs and effectiveness in detecting cancer. Given the low prevalence of GU malignant abnormality among patients with AMH, it is important to quantify the cost implications of detecting cancer for each approach. Objective: To estimate the effectiveness, costs, and incremental cost per cancer detected (ICCD) for 4 common diagnostic approaches evaluating AMH...
April 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28413518/effect-of-n-acetylglucosamine-administration-on-cartilage-metabolism-and-safety-in-healthy-subjects-without-symptoms-of-arthritis-a-case-report
#10
Daiki Kubomura, Tomoya Ueno, Masanori Yamada, Akihito Tomonaga, Isao Nagaoka
N-acetylglucosamine (GlcNAc) is a widely accepted treatment for osteoarthritis (OA); however, its effect on healthy individuals is poorly understood. To evaluate the effect of GlcNAc administration on healthy subjects that do not exhibit symptoms of arthritis, the present randomized, double-blind, placebo-controlled study was performed. In the present study, 68 male and female Japanese participants, without symptomatic and radiographic evidence of OA, were enrolled and randomly allocated to receive placebo or GlcNAc (500 or 1,000 mg/day) for 16 weeks...
April 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28399523/sperm-sediment-cytology-a-new-technique-for-diagnosing-occult-urologic-infections
#11
Zhanna Sapozhkova, Karina Kasoyan, Elena Kovalchuk, Irina Shabalova
BACKGROUND: Ill-defined chronic symptoms such as itching, burning, urethral discharge, and pelvic pain are not uncommon in male urologic patients. Often, microscopic urinalysis, bacterial cultures, and laboratory testing are non-contributory. We have developed a technique for sperm sedimentation and used the cytologic examination of the sediment routinely in more than 4,000 patients with urologic complaints over the last 5 years. CASE: We present 3 exemplary cases, documenting the diagnostic power of sperm sediment cytology (SSC)...
April 12, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28394525/-ejaculate-and-serum-procalcitonin-levels-in-healthy-men-and-men-with-oligoasthenozoospermia
#12
D Yu Sosnin, N A Zubareva, O Yu Nenasheva, A V Krivtsov, N V Karimova, N V Pozdin
INTRODUCTION: Seminal plasma composition reflects the activity of reproductive organs involved in the semen production. AIM: To study procalcitonin concentrations in serum and semen samples of healthy men and men with oligoasthenozoospermia. METHOD: s .The study included 88 men, who were scheduled for diagnostic evaluation to establish the cause of infertile marriages. The study group comprised 40 men with oligoasthenozoospermia, the comparison group included 48 men with normal sperm concentration...
April 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28391960/rapid-detection-of-urinary-tract-infections-via-bacterial-nuclease-activity
#13
Katie S Flenker, Elliot L Burghardt, Nirmal Dutta, William J Burns, Julia M Grover, Elizabeth J Kenkel, Tyler M Weaver, James Mills, Hyeon Kim, Lingyan Huang, Richard Owczarzy, Catherine A Musselman, Mark A Behlke, Bradley Ford, James O McNamara
Rapid and accurate bacterial detection methods are needed for clinical diagnostic, water, and food testing applications. The wide diversity of bacterial nucleases provides a rich source of enzymes that could be exploited as signal amplifying biomarkers to enable rapid, selective detection of bacterial species. With the exception of the use of micrococcal nuclease activity to detect Staphylococcus aureus, rapid methods that detect bacterial pathogens via their nuclease activities have not been developed. Here, we identify endonuclease I as a robust biomarker for E...
April 5, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28382905/hematospermia-a-symptom-with-many-possible-causes
#14
Michael J Mathers, Stefan Degener, Herbert Sperling, Stephan Roth
BACKGROUND: Hematospermia, or blood in the ejaculate, is a symptom with many possible causes that often gives rise to worry. Precise figures on its prevalence are unavailable. It is most common in men under 40, and its cause is usually benign; nonetheless, even a single episode of hematospermia calls for a basic diagnostic evaluation. METHODS: This review is based on pertinent articles re trieved by a search in PubMed with the key words "hemato spermia," "hemospermia," "ejaculation," "male semen," and "transrectal ultrasound...
March 17, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28380686/efficacy-of-treatment-with-pseudoephedrine-in-men-with-retrograde-ejaculation
#15
O Shoshany, N Abhyankar, J Elyaguov, C Niederberger
The use of pseudoephedrine, an alpha agonist, for the treatment of retrograde ejaculation is well-known, however, there is no clear consensus from the literature regarding its efficacy and treatment protocol. We evaluated the efficacy of pseudoephedrine treatment in patients with retrograde ejaculation, utilizing a yet undescribed short-period treatment protocol. Twenty men were medically treated with pseudoephedrine for retrograde ejaculation between January 2010 and May 2016 (12 with complete retrograde ejaculation and 8 with partial retrograde ejaculation)...
April 5, 2017: Andrology
https://www.readbyqxmd.com/read/28379113/comparison-of-health-parameters-in-normal-cats-fed-a-limited-iodine-prescription-food-vs-a-conventional-diet
#16
Inke Paetau-Robinson, Lynda D Melendez, S Dru Forrester, Laura J Armbrust, Kent R Refsal, Patricia A Burris
Objectives The objective was to compare the effect on thyroid function in healthy, adult cats fed a limited iodine food or conventional diet for 24 months. Methods Cats in the limited iodine group (n = 14) were fed a commercial, dry food containing 0.2 ppm iodine on a dry-matter basis (DMB). Cats in the conventional diet group (n = 12) were fed an identical diet except that the iodine content was 3.2 ppm on a DMB. Both groups were maintained on their respective diets for 24 months. The median age of the cats at baseline was 3...
April 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28378068/a-minimal-impact-of-long-term-s-flurbiprofen-plaster-application-on-kidney-function-in-osteoarthritis-patients
#17
Noboru Otsuka, Ikuko Yataba, Isao Matsushita, Hideo Matsumoto, Yuichi Hoshino, Yoshio Terada
BACKGROUND: The number of kidney injury due to nonsteroidal anti-inflammatory drugs (NSAIDs) is the largest among drug-induced kidney diseases. Newly developed NSAID plaster containing S-flurbiprofen (SFP) shows innovative percutaneous absorption. However, systemic exposure to SFP following the repeated application of 80 mg/day was estimated as comparable to that of oral 120 mg/day flurbiprofen and prolonged use of topical NSAIDs is common in clinical practice. Thus, we report the safety focusing on the kidney function after long-term application of SFP plaster (SFPP)...
April 4, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28375917/urogenital-symptoms-in-neurologic-patients
#18
Jalesh N Panicker
PURPOSE OF REVIEW: Lower urinary tract and sexual dysfunction are commonly reported sequelae of neurologic disease and have a significant impact on quality of life. This article presents an up-to-date summary of the clinical presentation, investigations, and treatment options for urogenital dysfunction in patients with neurologic disease. RECENT FINDINGS: The pattern of lower urinary tract dysfunction is influenced by the site of the neurologic lesion. The risk for developing upper urinary tract damage is considerably less in patients with slowly progressive nontraumatic neurologic disorders, as compared to those with spinal cord injury or spina bifida...
April 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28372551/kidney-disease-in-uganda-a-community-based-study
#19
Robert Kalyesubula, Joaniter I Nankabirwa, Isaac Ssinabulya, Trishul Siddharthan, James Kayima, Jane Nakibuuka, Robert A Salata, Charles Mondo, Moses R Kamya, Donald Hricik
BACKGROUND: Chronic kidney disease (CKD) is a major cause of morbidity and mortality in Sub-Saharan Africa (SSA). The majority of studies on CKD in SSA have been conducted among HIV-infected populations and mainly from large health facilities. We determined the prevalence of CKD and its predictors among populations in communities in central Uganda. METHODS: A cross-sectional study was conducted in Wakiso district using multi-stage sampling. Data was collected on age, sex, socio-economic status, history of alcohol intake, diabetes mellitus, hypertension and smoking...
April 3, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28371167/long-term-sexual-health-outcomes-in-men-with-classic-bladder-exstrophy
#20
Timothy S Baumgartner, Kathy M Lue, Pokket Sirisreetreerux, Sarita Metzger, Ross G Everett, Sunil S Reddy, Ezekiel Young, Uzoma A Anele, Cameron E Alexander, Nilay M Gandhi, Heather N Di Carlo, John P Gearhart
OBJECTIVES: To identify the long-term sexual health outcomes and relationships in men born with classic bladder exstrophy (CBE). MATERIALS AND METHODS: A prospectively-maintained institutional database comprised of 1248 patients with exstrophy-epispadias was utilized. Male patients 18 years or older with CBE were included. A 42-question survey was designed utilizing a combination of demographic information and previously validated questionnaires. RESULTS: A total of 215 men inclusion criteria, of which 113 (53%) completed the questionnaire...
March 31, 2017: BJU International
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