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https://www.readbyqxmd.com/read/28633169/untapped-potential-performance-of-procedural-skills-in-the-family-medicine-clerkship
#1
Martina Kelly, Kelly M Everard, Lara Nixon, Alexander Chessman
BACKGROUND AND OBJECTIVES: While family medicine residency directors have expressed concern about low procedural skills proficiency among incoming residents, curricular recommendations do not provide widely accepted guidance. This study was designed to describe requirements and experiences in procedural skill training during the family medicine clerkship and test the hypothesis that more rural placements may support this training. METHODS: The survey was conducted as part of the CAFM Educational Research Alliance (CERA) Family Medicine Clerkship Director (CD) 2013 survey...
June 2017: Family Medicine
https://www.readbyqxmd.com/read/28631912/-results-of-urethral-reconstruction-in-adults-after-multiple-hypospadias-repairs
#2
S I Gamidov, M G Shneiderman, D Yu Pushkar, A O Vasil'ev, A V Govorov, R I Ovchinnikov, A Yu Popova, R D Dusmukhamedov
AIM: To improve treatment results in patients after multiple hypospadias repairs by optimizing the postoperative management. MATERIALS AND METHODS: Eighty-two patients (mean age 48.1+/-15.3 years) with urethral strictures secondary to failed hypospadias repairs underwent staged graft urethroplasty using oral mucosa (cheek, lip, tongue) as a grafting material. In 62 patients, at the end of surgery the bladder was drained with a standard Foley catheter. In twenty patients the bladder was drained with a modified silicone urethral catheter, which had an additional channel for delivering drugs and removing the urethral wound effluent, and a second additional channel for inflating a balloon fixed to the catheter tube at different parts of the catheter...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28631910/-prevalence-and-risk-factors-for-nephrolithiasis-among-young-rural-residents
#3
A V Sin'kov, I N Volosatova, G M Sin'kova, L A Nikolaeva
AIM: To determine the prevalence of nephrolithiasis, assess the significance of known risk factors, and identify new risk factors for nephrolithiasis among young rural residents. MATERIALS AND METHODS: This cross-sectional study was conducted in 5 settlements of the Irkutsk rural district of the Irkutsk region and involved 408 inhabitants (93 men, 315 women) aged from 18 to 47 years. The selection of candidates for the study was randomized. The response of the population was 81...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28630631/urinalysis-and-clinical-correlations-in-patients-with-p-vivax-or-p-falciparum-malaria-from-colombia
#4
Alberto Tobón-Castaño, Sebastián Barrera Escobar, Cecilia Giraldo Castro
BACKGROUND: Urinalysis is a poorly reviewed diagnostic tool in malaria patients; its application can show the presence of severe malaria. METHODS: Urinalysis was performed in a total of 620 patients diagnosed with malaria by thick blood smear; complications were classified according to WHO major criteria for severity and minor criteria according to the Colombian malaria guideline. RESULTS: Severe or moderate clinical complications were diagnosed in 31...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28626171/association-between-overall-lifestyle-changes-and-the-incidence-of-proteinuria-a-population-based-cohort-study
#5
Minako Wakasugi, Junichiro Kazama, Ichiei Narita, Kunitoshi Iseki, Shouichi Fujimoto, Toshiki Moriyama, Kunihiro Yamagata, Tsuneo Konta, Kazuhiko Tsuruya, Koichi Asahi, Masahide Kondo, Issei Kurahashi, Yasuo Ohashi, Kenjiro Kimura, Tsuyoshi Watanabe
Objective This study aimed to examine the association between the changes in an overall healthy lifestyle, as quantified by the number of unhealthy lifestyle factors and obesity status, and the incidence of proteinuria in the general Japanese population. Methods A retrospective cohort study was conducted among 99,404 (men, 36.9%) participants aged from 40-74 years of age who underwent two health check-ups with a 1-year interval in Japan between 2008 and 2009. Any participants with chronic kidney disease at baseline were excluded...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28624472/nonclinical-safety-of-astilbin-a-4-week-oral-toxicity-study-in-rats-with-genotoxicity-chromosomal-aberration-and-mammalian-micronucleus-tests
#6
Yonglin Gao, Chunmei Li, Yunzhi Wang, Yunguo Liu, Guisheng Li, Xiaochen Fan, Yanshen Li, Jingwei Tian, Albert W Lee
Astilbin is an active flavonoid compound isolated from Rhizoma Smilacis Glabrae. It has been widely used as an anti-hepatic, anti-arthritic, and anti-renal injury agent. However, its safety has not yet been established. The objective of this study was to evaluate 4-week repeated oral toxicity and genotoxicity of astilbin. We examined oral toxicity in Sprague-Dawley rats after daily oral administration of astilbin at 50, 150, and 500 mg/kg for 4 weeks. Negative control animals received the same volume of the solvent...
June 14, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28620946/incidental-detection-of-asymptomatic-migration-of-hem-o-lok-clip-into-the-bladder-after-laparoscopic-radical-prostatectomy
#7
Junpei Iizuka, Yasunobu Hashimoto, Tsunenori Kondo, Toshio Takagi, Keisuke Hata, Taichi Kanzawa, Hidekazu Tachibana, Kazuhiko Yoshida, Kazunari Tanabe
Hem-o-lok clips have been widely used in laparoscopic or robot-assisted surgery. We report a case of an incidentally discovered Hem-o-lok migration into the bladder after laparoscopic radical prostatectomy. The patient was a 75-year-old man with localized prostate cancer who underwent laparoscopic radical prostatectomy in July 2009. At 3 postoperative years, follow-up ultrasonography revealed a small round mass in the bladder. No lower urinary tract symptoms were reported, and urinalysis results had never indicated hematuria or pyuria...
June 15, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28611901/a-comparison-of-urolithiasis-in-the-presence-and-absence-of-microscopic-hematuria-in-the-emergency-department
#8
Jason M Mefford, Robert M Tungate, Leila Amini, Dongjin Suh, Craig L Anderson, Scott E Rudkin, Megan Boysen-Osborn
INTRODUCTION: Urolithiasis is a common medical condition that accounts for a large number of emergency department (ED) visits each year and contributes significantly to annual healthcare costs. Urinalysis is an important screening test for patients presenting with symptoms suspicious for urolithiasis. At present there is a paucity of medical literature examining the characteristics of ureteral stones in patients who have microscopic hematuria on urinalysis versus those who do not. The purpose of this study was to examine mean ureteral stone size and its relationship to the incidence of clinically significant hydronephrosis in patients with and without microscopic hematuria...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28604639/inhibitory-effects-of-diclofenac-on-steroid-glucuronidation-in-vivo-do-not-affect-hair-based-doping-tests-for-stanozolol
#9
Gergely Zachár, Naved I K Deshmukh, Andrea Petróczi, Andrea D Székely, Iltaf Shah, James Barker, Declan P Naughton
In vitro studies show that diclofenac inhibits enzymatic steroid glucuronidation. This study was designed to investigate the influence of diclofenac on the excretion of stanozolol and 3'-hydroxystanozolol via analyses in hair, blood and urine in vivo in a rat study. Brown Norway rats were administered with stanozolol (weeks 1-3) and diclofenac (weeks 1-6). Weekly assessment of steroid levels in hair was complemented with spot urine and serum tests. Levels of both stanozolol and 3'-hydroxystanozolol steadily increased in hair during stanozolol treatment and decreased post-treatment, but remained readily detectable for 6 weeks...
June 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28601117/tubular-urinary-indexes-reliably-distinguish-between-primary-tubulointerstitial-and-primary-glomerular-diseases-in-patients-referred-for-kidney-biopsy
#10
Andrej Škoberne, Špela Borštnar, Nuša Avguštin, Damjan Kovač, Andreja Aleš Rigler, Željka Večerić-Haler, Jernej Pajek, Mladen Krsnik, Nika Kojc, Dušan Ferluga, Jelka Lindič
AIMS: Kidney biopsy remains the gold standard for accurately diagnosing renal diseases. Urinalysis and assessment of renal function are the cornerstones for assessment of patients prior to biopsy. There is significant overlap in the results of routine urine parameters (proteinuria, erythrocyturia, leukocyturia) among different kidney diseases, which hinders the possibility of adequately estimating disease etiology prior to the biopsy. The aim of our study was to assess whether diverse markers of glomerular and tubular proteinuria - urinary albumin, IgG, α-1-microglobulin (α-1-m) and N-acetyl-β-D-glucosaminidase (NAG) - are capable of distinguishing between patients with primary tubulointerstitial (TID) and primary glomerular disease (GLOM)...
June 9, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28587696/uncomplicated-urinary-tract-infections-in-the-emergency-department-a-review-of-local-practice-patterns
#11
Elizabeth Poon, Lauren Self, Shelley L McLeod, Sean Caine, Bjug Borgundvaag
OBJECTIVES: To determine the number of urine cultures ordered for women who presented to the emergency department (ED) with symptoms of uncomplicated UTI, and whether a culture result impacted subsequent management. METHODS: This was a retrospective chart review of non-pregnant women aged 18-39 presenting to one of two academic EDs with a discharge diagnosis of uncomplicated UTI over a one-year study period. Patients were excluded if there was documentation of fever, immunocompromised state, diabetes mellitus, absence of lower urinary tract symptoms, ED administration of intravenous antibiotics, a previous UTI treated with antibiotics in the last 90 days, two weeks post-partum or post-instrumentation...
June 7, 2017: CJEM
https://www.readbyqxmd.com/read/28581908/urinalysis-in-the-cat-measurement-of-urine-protein-creatinine-ratio
#12
Adam Heeley
No abstract text is available yet for this article.
November 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28577157/analysis-of-the-incidence-and-risk-factors-of-male-urinary-tract-infection-following-urodynamic-study
#13
Z Huang, H Xiao, H Li, W Yan, Z Ji
The purpose of this study was to investigate the incidence and risk factors of male urinary tract infection (UTI) after urodynamic study (UDS). A total of 854 consecutive male patients, who underwent UDS at Peking Union Medical College Hospital from January 2010 to March 2016, were recruited in this study. Two to four weeks before the examination, urinalysis with bacterial culture was performed. Patients with negative results were selected for UDS. Immediately before the examination, urinalysis was repeated to rule out any preoperative UTI...
June 2, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28557682/an-infant-presenting-with-failure-to-thrive-and-hyperkalaemia-owing-to-transient-pseudohypoaldosteronism-case-report
#14
Marieke De Clerck, Johan Vande Walle, Evelyn Dhont, Joke Dehoorne, Werner Keenswijk
A 3-month-old boy presented with failure to thrive and a history of a prenatally detected unilateral hydroureteronephrosis which was confirmed after birth. His growth and developmental milestones had been normal during the first 2 months but in the third month his appetite was poor with reduced intake but no vomiting. At presentation, his temperature was normal, there was mild dehydration and there was weight loss (his weight had decreased by 270 g in the past month). Haemoglobin was 11.9 g/dL, total white cell count 20...
May 30, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28557062/substance-related-psychopathology-and-aggressiveness-in-a-nightlife-holiday-resort-results-from-a-pilot-study-in-a-psychiatric-inpatient-unit-in-ibiza
#15
Giovanni Martinotti, Eduardo Cinosi, Rita Santacroce, Duccio Papanti, Anna Pasquini, Valerio Mancini, Mariangela Corbo, Federica Fiori, Fabiola Sarchione, Daniela Marchetti, Maria Cristina Verrocchio, Massimo Di Giannantonio, Marta Torrens, Fabrizio Schifano, Maria Jose Morlan Coarasa, Cristina Merino Del Villar
OBJECTIVES: We aimed to describe a sample of subjects admitted to a psychiatric unit after the intake of psychoactive substances for recreational purposes. METHODS: Between June and September 2015, 49 subjects were included. Sociodemographic characteristics and psychopathological aspects were investigated, and urine samples for further analysis were collected. Three subgroups (cannabinoids, stimulants, and depressors users) were identified, according to the structured interview regarding substance use and urinalysis...
May 30, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28556290/moderate-to-high-normal-levels-of-thyrotropin-is-a-risk-factor-for-urinary-incontinence-and-an-unsuitable-quality-of-life-in-women-over-65-years
#16
Estela Cuevas-Romero, Angélica Sánchez-Cardiel, Angélica M Zamora-Gallegos, Rosalía Cruz-Lumbreras, Dora L Quintanilla, Francisco Castelán, Margarita Martínez-Gómez
The present study was aimed to investigate the relationship between normal serum concentrations of thyrotropin (TSH) and urinary incontinence (IU), urinary infections, and quality of life in old women. Euthyroid post-menopausal women without sarcopenia, estrogen replacement, emotional illness, and-or cancer were enrolled as participants. Anthropometric indicators, serum glucose and estradiol, and thyroid profile were measured. Sociodemographic, clinical, physical activity, and quality of life (SF-36) surveys were applied...
May 28, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28541143/an-algorithm-for-identifying-mothball-composition
#17
Michael J Moss, Kevin F Maskell, Michelle A Hieger, Brandon K Wills, Kirk L Cumpston
INTRODUCTION: Unintentional mothball ingestions may cause serious toxicity in small children. Camphor, naphthalene, and paradichlorobenzene mothballs are difficult to distinguish without packaging. Symptoms and management differ based on the ingested compound. Previous studies have used a variety of antiquated, impractical and potentially dangerous techniques to identify the mothballs. The goal of this study is to discover a simplified identification technique using materials readily available in an emergency department...
May 25, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28539089/simulating-real-life-exposures-to-uncover-possible-risks-to-human-health-a-proposed-consensus-for-a-novel-methodological-approach
#18
A M Tsatsakis, D Kouretas, M N Tzatzarakis, P Stivaktakis, K Tsarouhas, K S Golokhvast, V N Rakitskii, V A Tutelyan, A F Hernandez, R Rezaee, G Chung, C Fenga, A B Engin, M Neagu, A L Arsene, A O Docea, E Gofita, D Calina, I Taitzoglou, J Liesivuori, A W Hayes, S Gutnikov, C Tsitsimpikou
In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't assess the overall risk of chemicals present in a mixture. This study will evaluate the cumulative toxicity of mixtures of different classes of pesticides and mixtures of different classes of pesticides together with food additives (FAs) and common consumer product chemicals using realistic doses after long-term exposure...
June 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28535882/versatile-fabrication-of-paper-based-microfluidic-devices-with-high-chemical-resistance-using-scholar-glue-and-magnetic-masks
#19
Thiago M G Cardoso, Fabrício R de Souza, Paulo T Garcia, Denilson Rabelo, Charles S Henry, Wendell K T Coltro
Simple methods have been developed for fabricating microfluidic paper-based analytical devices (μPADs) but few of these devices can be used with organic solvents and/or aqueous solutions containing surfactants. This study describes a simple fabrication strategy for μPADs that uses readily available scholar glue to create the hydrophobic flow barriers that are resistant to surfactants and organic solvents. Microfluidic structures were defined by magnetic masks designed with either neodymium magnets or magnetic sheets to define the patter, and structures were created by spraying an aqueous solution of glue on the paper surface...
June 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28533937/a-phase-one-single-dose-open-label-clinical-safety-and-pet-mr-imaging-study-of-68-ga-dotatoc-in-healthy-volunteers
#20
Shadi A Esfahani, Stephanie Salcedo, Pedram Heidari, Onofrio A Catalano, Rachel Pauplis, Jacob Hesterman, James F Kronauge, Umar Mahmood
This prospective pilot study provides a dynamic whole body PET/MR image database, clinical safety, biodistribution profile and dosimetry of (68)Ga-DOTATOC in healthy subjects, to establish a baseline and standard reference for its use in diagnosis and treatment response evaluation among patients with somatostatin receptor expressing neoplastic diseases. Dynamic whole body PET/MR imaging was performed in 12 healthy subjects (male/female: 8/4) after injection of 242.39 ± 53.38 MBq (mean ± SD) (68)Ga-DOTATOC...
2017: American Journal of Nuclear Medicine and Molecular Imaging
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