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Yanzhuo Ma, Lingfeng Kong, Shuying Qi, Dongmei Wang
BACKGROUND: This study investigated effects of exhaustive exercise on L-type calcium current (ICa,L) and the putative intracellular cascade responsible for the effects. METHODS: Rats were randomly divided into three treatment groups: sedentary (without exercise), exercised to exhaustion and salubrinal injection before each exhaustive exercise period. Exercise group rats were forced to swim until exhaustion each time for 9 days with 5% body weight attached to the head...
April 2017: Journal of Sports Medicine and Physical Fitness
Min-Kyung Jang, Ye-Rang Yun, Ji-Hyun Kim, Mi-Hee Park, Myeong Ho Jung
Gomisin N (GN) is a physiological lignan derived from Schisandra chinensis. In the present study, we investigated the inhibitory effects of GN on differentiation of 3T3-L1 preadipocytes and the anti-obesity effects of GN in high-fat diet (HFD)-induced obese mice. Incubation with GN significantly inhibited the differentiation of 3T3-L1 preadipocytes in a dose-dependent manner. This inhibitory effect primarily occurred at an early adipogenic stage through impairment of mitotic clonal expansion (MCE) caused by cell cycle arrest at the G1/S phase transition...
January 9, 2017: Scientific Reports
Yamin Wang, Huangzhao Wei, Ying Zhao, Wenjing Sun, Chenglin Sun
The sludge-derived carbon catalyst modified with 0°C HNO3 solution was tested in catalytic wet peroxide oxidation of m-cresol (100mgL(-1)) with systematical mathematical models and theoretical calculation for the first time. The reaction conditions were optimized by response surface methodology (RSM) as T=60°C, initial pH=3.0, C0,H2O2(30%)=1.20gL(-1) (lower than the stoichiometric amount of 1.80gL(-1)) and Ccat=0.80gL(-1), with 96% of m-cresol and 47% of TOC converted after 16min and 120min of reaction, respectively, and ξ (mg TOC/g H2O2 fed)=83...
December 8, 2016: Journal of Hazardous Materials
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No abstract text is available yet for this article.
2016: Psycho-oncology
H Qu, H Yan, H Lu, S S Donkin, K M Ajuwon
Heat stress (HS) negatively affects all aspects of performance in pigs. Although certain tissue-specific responses in the liver, skeletal muscle, and intestine are known, there is paucity of information on responses within the adipose tissue. Therefore, the objective of this study was to delineate adipose tissue responses during HS in pigs. Thirty crossbred (Ossabaw × Duroc × Landrace) pigs were assigned to 3 treatments for 7 d. Treatments were 1) control and libitum fed (CON) with room temperature set at 20°C ± 1°C, 2) pair fed (PF) with room temperature as the CON treatment but pair fed to HS pigs, and 3) HS with room temperature 35°C ± 1°C and ad libitum access to feed...
May 2016: Journal of Animal Science
Guan-Yu Lin, Hsiu-Yu Chan, Chun-An Cheng, Lan-Ping Lin, Giia-Sheun Peng, Pei-Min Hsiao, Chun-Chieh Lin, Chun-Chih Lin, Jiunn-Tay Lee
BACKGROUND AND OBJECTIVES: This study aimed to explore the effect of functional foods on aphasia related to a previous ischemic stroke. When stroke-related neurological deficits result in physical dependency and poor selfcare that persists longer than 6 months, full recovery is almost impossible and the patient often requires long-term care. The functional foods, EASE123 and BioBalance#6, include numerous plant and marine-based nutrient supplements that could prove beneficial for such patients...
2016: Asia Pacific Journal of Clinical Nutrition
Yanzhuo Ma, Lingfeng Kong, Shuying Qi, Dongmei Wang
BACKGROUND: This study investigated effects of exhaustive exercise on L-type calcium current (ICa,L) and the putative intracellular cascade responsible for the effects. METHODS: Rats were randomly divided into three treatment groups: sedentary (without exercise), exercised to exhaustion and salubrinal injection before each exhaustive exercise period. Exercise group rats were forced to swim until exhaustion each time for 9 days with 5% body weight attached to the head...
February 10, 2016: Journal of Sports Medicine and Physical Fitness
Fiona M Corrigan, Helen Broome, Liam Dorris
BACKGROUND: Despite recognition that psychosocial interventions can improve quality of life and mental health, there continues to be a lack of clarity and guidance around effective psychosocial interventions for children and young people with epilepsy. This review utilizes specific quality criteria to systematically identify and appraise the evidence for the effectiveness of psychosocial interventions for children and young people with epilepsy. METHODS: A systematic search of six electronic databases was conducted using predefined eligibility criteria...
March 2016: Epilepsy & Behavior: E&B
Chih-Ting Chang, Chia-Ying Lee, Chia-Ju Chou, Jong-Ling Fuh, Hsin-Chi Wu
Predictability effect on N400, in which low predictability words elicited a larger N400 than high predictability words did over central to posterior electrodes, has been used to index difficulty of lexical retrieval and semantic integration of words in sentence comprehension. This study examined predictability effect on N400 in aphasic patients to determine if the properties of N400 are suited to indexing the severity of reading comprehension deficits. Patients with aphasia were divided into high and low ability groups based on scores on the reading comprehension subtest in the Chinese Concise Aphasia Test (CCAT)...
January 29, 2016: Neuropsychologia
Hirotsugu Watabe, Tetsuya Nakamura, Atsuo Yamada, Yasuo Kakugawa, Sadaharu Nouda, Akira Terano
BACKGROUND: Training for colon capsule endoscopy (CCE) procedures is currently performed as a lecture and hands-on seminar. The aims of this pilot study were to assess the utility of an electronic learning system for CCE (ELCCE) designed for the Japanese Association for Capsule Endoscopy using an objective scoring engine, and to evaluate the efficacy of ELCCE on the acquisition of CCE reading competence. METHODS: ELCCE is an Internet-based learning system with the following steps: step 1, introduction; step 2, CCE reading competence assessment test (CCAT), which evaluates the competence of CCE reading prior to training; step 3, learning reading theory; step 4, training with guidance; step 5, training without guidance; step 6, final assessment; and step 7, the same as step 2...
June 2016: Journal of Gastroenterology
Edvin Prifti, Efrosina Kajo, Klodian Krakulli, Majlinda Ikonomi
A cardiac calcified amorphous tumour (CCAT) is a rare non-neoplastic intracavitary mass with unknown causes. We describe a 32-year old male presenting with progressive dyspnoea, cough and oedemas. The transthoracic echocardiography and contrast-enhanced angio-computed tomography demonstrated a 4 × 10 cm calcified mass into the right ventricle and total occlusion of the right pulmonary artery. The patient underwent successful total removal of the mass through a transverse right ventriculotomy, and right pulmonary embolectomy...
December 2015: Interactive Cardiovascular and Thoracic Surgery
Hua-Qiang Zhu, Xu Zhou, Hong Chang, Hong-Guang Li, Fang-Feng Liu, Chao-Qun Ma, Jun Lu
BACKGROUND: CCAT1 has been reported to be linked with pathogenesis of malignancies including colon cancer and gastric cancer. However, the regulatory effect of CCAT1 in hepatocellular carcinoma (HCC) remains unclear. The purpose of this research was to identify any role of CCAT1 in the progression of HCC. MATERIALS AND METHODS: Real time-PCR was performed to test the relative expression of CCAT1 in HCC tissues. A computation screen of CCAT1 promoter was conducted to search for transcription-factor-binding sites...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
Zhenyu Ye, Ming Zhou, Bin Tian, Bin Wu, Juncheng Li
OBJECTIVE: To explore the expression and clinical significance of IncRNA-CCAT and EMT related molecule E-cadherin and N-cadherin in colorectal cancer. METHODS: The expression of IncRNA-CCAT1, E-cadherin and N-cadherin in 37 colorectal cancer tissue and para-carcinoma tissue was detected using qRT-PCR method, and the correlation of expression level with clinical and pathological features was studied. RESULTS: The expression of IncRNA-CCAT1 in tumor tissue was significantly higher than that in normal para-carcinoma tissue (P < 0...
2015: International Journal of Clinical and Experimental Medicine
Nora-Ann Donnelly, Anne Hickey, Annette Burns, Paul Murphy, Frank Doyle
BACKGROUND: In the caregiving literature there is a common assertion that a higher level of carer stress is a critical determinant of premature ending of homecare. However, this contention has not been systematically assessed. We therefore systematically reviewed and meta-analysed the prospective association between various forms of carer stress and subsequent institutionalisation of community-dwelling older people. METHODS: Systematic literature search of prospective studies measuring carer stress at baseline and institutionalisation at follow-up...
2015: PloS One
Claudia Angelini, Ruth Heller, Rita Volkinshtein, Daniel Yekutieli
BACKGROUND: Chip-seq experiments are becoming a standard approach for genome-wide profiling protein-DNA interactions, such as detecting transcription factor binding sites, histone modification marks and RNA Polymerase II occupancy. However, when comparing a ChIP sample versus a control sample, such as Input DNA, normalization procedures have to be applied in order to remove experimental source of biases. Despite the substantial impact that the choice of the normalization method can have on the results of a ChIP-seq data analysis, their assessment is not fully explored in the literature...
May 9, 2015: BMC Bioinformatics
Susan M Stankorb, Casside Ramsey, Heidi Clark, Tamara Osgood
This article describes the experience of nutrition support practitioners, specifically dietitians, providing care to combat casualties. It provides a brief overview of dietitians' induction into armed service but focuses primarily on their role in providing nutrition support during the most recent conflicts in Iraq and Afghanistan. The current system of combat casualty care is discussed with specific emphasis on providing early and adequate nutrition support to U.S. combat casualties from injury, care in theater combat support hospitals (CSHs)/expeditionary medical support (EMEDs), and en route care during critical care air transport (CCAT) up to arrival at treatment facilities in the United States...
October 2014: Nutrition in Clinical Practice
Abdulbasit M Abeish, Ha Ming Ang, Hussein Znad
The solar-photocatalytic degradation mechanisms and kinetics of 4-chlorophenol (4-CP) and 2,4-dichlorophenol (2,4-DCP) using TiO2 have been investigated both individually and combined. The individual solar-photocatalytic degradation of both phenolic compounds showed that the reaction rates follow pseudo-first-order reaction. During the individual photocatalytic degradation of both 4-CP and 2,4-DCP under the same condition of TiO2 (0.5 g L(-1)) and light intensities (1000 mW cm(-2)) different intermediates were detected, three compounds associated with 4-CP (hydroquinone (HQ), phenol (Ph) and 4-chlorocatechol (4-cCat)) and two compounds associated with 2,4-DCP (4-CP and Ph)...
2015: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
Biao Dong, Honglan Zhou, Conghui Han, Jufang Yao, Longmei Xu, Ming Zhang, Yaowen Fu, Qiang Xia
Endoplasmic reticulum (ER) stress-induced apoptosis is implicated in a wide range of diseases, including ischemia/reperfusion injury (IRI). As a common feature of ER stress, the role of CCAT/enhancer-binding protein homologous protein (CHOP) in renal IRI has not been thoroughly investigated. We found that IR led to renal CHOP expression, accompanied by apoptosis induction. Renal IRI was markedly alleviated in CHOP-/- mice. Observations from bone marrow chimeras showed that this was based on CHOP inactivation in renal parenchymal cells rather than inflammatory cells...
2014: PloS One
Katsiaryna Laryionava, Halina Sklenarova, Pia Heußner, Markus W Haun, Anne M Stiggelbout, Mechthild Hartmann, Eva C Winkler
BACKGROUND: Decision-making with patients with incurable cancer often requires trade-offs between quality and length of life. The 'Quality and Quantity Questionnaire' (QQ) is an English-language measure of patients' preference for length or quality of life. The aim of this study was to translate and validate this questionnaire. MATERIALS AND METHODS: 1 new item was formulated to improve the 'Quality of life' scale. Construct validity including exploratory factor analysis, convergent and discriminant validity, and reliability was determined in n = 194 patients...
2014: Oncology Research and Treatment
Markus W Haun, Halina Sklenarova, Anette Brechtel, Wolfgang Herzog, Mechthild Hartmann
BACKGROUND: Discrepancies within cancer-affected couples can disrupt security within the dyadic relationship during cancer treatment. This study investigated the patients' and caregivers' distress and associations between the caregivers' perception of the patients' degree of open communication and their distress. PARTICIPANTS AND METHODS: In a cross-sectional survey, 189 pairs of cancer patients (31% gastrointestinal, 34% lung, 35% urological cancers) and their partners were assessed for distress (QSC-R10), depression and anxiety (PHQ-2/GAD-2)...
2014: Oncology Research and Treatment
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