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https://www.readbyqxmd.com/read/29232574/imaging-analysis-of-superficial-soft-tissue-lymphomas
#1
In Sook Lee, You Seon Song, Seung Hyun Lee, Young Jin Choi, Sung Moon Lee
PURPOSE: To describe imaging findings in superficial soft tissue lymphomas, especially those located in the skin and subcutaneous layer. MATERIALS AND METHODS: This study included 44 pathologically confirmed superficial lymphoma lesions. Imaging analysis included the size, margin, location, morphology, homogeneity and multiplicity. RESULTS: A nodular form was the most common (21/44, 47.7%) morphology, and of them, 18 demonstrated a streaky appearance...
November 20, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29232164/effect-of-ct-on-management-plan-in-malleolar-ankle-fractures
#2
Ashwani Kumar, Puneet Mishra, Anupama Tandon, Rajesh Arora, Manish Chadha
BACKGROUND: Conventionally ankle fractures have been classified using plain radiographs. Because of complex 3-dimensional anatomy and complexity of injuries, plain radiographs may not always be able to clearly depict the complete fracture pattern. There is a paucity of studies regarding the utility of computed tomography (CT) scanning in malleolar ankle fractures (MAFs). Hence, we conducted this study to further understand the role of the CT scan in MAFs. METHODS: A prospective study of 56 consecutive malleolar ankle fractures was conducted...
November 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29232145/patterning-conjugated-polymers-by-laser-synergy-of-nanostructure-formation-in-the-all-polymer-heterojunction-p3ht-pcdtbt
#3
Álvaro Rodriguez-Rodriguez, Esther Rebollar, Tiberio A Ezquerra, Marta Castillejo, Jose Vicente Garcia-Ramos, Mari Cruz García-Gutiérrez
In this work we report a broad scenario for the patterning of semiconducting polymers by laser-induced periodic surface structures (LIPSS). Based on the LIPSS formation in the semicrystalline poly(3-hexylthiophene) (P3HT), we have extended the LIPSS fabrication to an essentially amorphous semiconducting polymer like poly[N-90-heptadecanyl-2,7-carbazole-alt-5,5-(40,70-di-2-thienyl-20,10,30 benzothiadiazole)] (PCDTBT). This polymer shows a good quality and well-ordered nanostructures not only at the 532 nm laser wavelength, as in the case of P3HT, but also at 266 nm providing gratings with smaller pitch...
December 12, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29231140/up-regulation-of-dmn-connectivity-in-mild-cognitive-impairment-via-network-based-cognitive-training
#4
Matteo De Marco, Francesca Meneghello, Cristina Pilosio, Jessica Rigon, Annalena Venneri
BACKGROUND: Previous work designed a network-based protocol of cognitive training. This programme exploits a mechanism of induced task-oriented co-activation of multiple regions that are part of the default mode network (DMN), to induce functional rewiring and increased functional connectivity within this network. OBJECTIVE: In this study, the programme was administered to patients with a diagnosis of mild cognitive impairment to test its effects in a clinical sample...
December 11, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29230354/ecomorphological-inferences-in-early-vertebrates-reconstructing-dunkleosteus-terrelli-arthrodira-placodermi-caudal-fin-from-palaeoecological-data
#5
Humberto G Ferrón, Carlos Martínez-Pérez, Héctor Botella
Our knowledge about the body morphology of many extinct early vertebrates is very limited, especially in regard to their post-thoracic region. The prompt disarticulation of the dermo-skeletal elements due to taphonomic processes and the lack of a well-ossified endoskeleton in a large number of groups hinder the preservation of complete specimens. Previous reconstructions of most early vertebrates known from partial remains have been wholly based on phylogenetically closely related taxa. However, body design of fishes is determined, to a large extent, by their swimming mode and feeding niche, making it possible to recognise different morphological traits that have evolved several times in non-closely related groups with similar lifestyles...
2017: PeerJ
https://www.readbyqxmd.com/read/29229930/controllable-plasmonic-nanostructures-induced-by-dual-wavelength-femtosecond-laser-irradiation
#6
Weina Han, Lan Jiang, Xiaowei Li, Qingsong Wang, Shaojun Wang, Jie Hu, Yongfeng Lu
We demonstrated an abnormal double-peak (annular shaped) energy deposition through dual-wavelength synthesis of the fundamental frequency (ω) and the second-harmonic frequency (2ω) of a femtosecond (fs) Ti:sapphire laser. The annular shaped distribution of the dual-wavelength fs laser was confirmed through real beam shape detection. This uniquely simple and flexible technique enables the formation of functional plasmonic nanostructures. We applied this double-peak fs-laser-induced dewetting effect to the controlled fabrication and precise deposition of Au nanostructures, by using a simple, lithography-free, and single-step process...
December 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29229818/accelerating-fishes-increase-propulsive-efficiency-by-modulating-vortex-ring-geometry
#7
Otar Akanyeti, Joy Putney, Yuzo R Yanagitsuru, George V Lauder, William J Stewart, James C Liao
Swimming animals need to generate propulsive force to overcome drag, regardless of whether they swim steadily or accelerate forward. While locomotion strategies for steady swimming are well characterized, far less is known about acceleration. Animals exhibit many different ways to swim steadily, but we show here that this behavioral diversity collapses into a single swimming pattern during acceleration regardless of the body size, morphology, and ecology of the animal. We draw on the fields of biomechanics, fluid dynamics, and robotics to demonstrate that there is a fundamental difference between steady swimming and forward acceleration...
December 11, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29229773/ap-2%C3%AE-and-ap-2%C3%AE-cooperatively-orchestrate-homeobox-gene-expression-during-branchial-arch-patterning
#8
Eric Van Otterloo, Hong Li, Kenneth L Jones, Trevor Williams
The evolution of a hinged moveable jaw with variable morphology is considered a major factor behind the successful expansion of the vertebrates. DLX homeobox transcription factors are critical to establish the positional code that patterns the mandible, maxilla and intervening hinge domain, but how these genes are regulated remains unclear. Herein, we demonstrate that the concerted action of the AP-2ɑ and AP-2β transcription factors within the mouse neural crest is essential for jaw patterning. In the absence of these two genes the hinge domain is lost and there are alterations in the size and patterning of the jaws correlating with dysregulation of homeobox gene expression, with reduced levels of Emx, Msx and Dlx paralogs accompanied by an expansion of Six1...
December 11, 2017: Development
https://www.readbyqxmd.com/read/29229494/classic-pattern-dyssynchrony-in-adolescents-and-adults-with-a-fontan-circulation
#9
Assami Rösner, Tigran Khalapyan, Håvard Dalen, Doff B McElhinney, Mark K Friedberg, George K Lui
BACKGROUND: Previous studies have suggested the presence of dyssynchrony in the functionally single ventricle. The aim of this study was to investigate the presence of classic-pattern dyssynchrony (CPD), characterized by typical early and late deformation of opposite walls, and its relation to QRS duration and myocardial function in patients with single-ventricle physiology after Fontan palliation. METHODS: In a retrospective cross-sectional study, 101 adolescent and adult patients with single-ventricle physiology after the Fontan procedure were investigated...
December 8, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29229338/delayed-occurrence-of-diabetes-insipidus-following-transsphenoidal-surgery-with-radiological-evaluation-of-the-pituitary-stalk-on-magnetic-resonance-imaging
#10
Yasuhiko Hayashi, Yasuhiro Aida, Yasuo Sasagawa, Masahiro Oishi, Daisuke Kita, Osamu Tachibana, Fumiaki Ueda, Mitsutoshi Nakada
INTRODUCTION: Diabetes insipidus (DI) is a major complication of transsphenoidal surgery (TSS). DI usually occurs within a couple of days after TSS. Delayed occurrence of postoperative DI is rarely observed and its developing mechanisms remain unknown. Methods Six patients were identified as having postoperative delayed DI, which was defined as DI that first occurred two or more weeks after TSS. They consisted of one male and five females, and their mean age was 38.3 (range: 10-76) years...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29228925/daily-activity-patterns-influence-retinal-morphology-signatures-of-selection-and-spectral-tuning-of-opsin-genes-in-colubrid-snakes
#11
E Hauzman, D M O Bonci, E Y Suárez-Villota, M Neitz, D F Ventura
BACKGROUND: Morphological divergences of snake retinal structure point to complex evolutionary processes and adaptations. The Colubridae family has a remarkable variety of retinal structure that can range from all-cone and all-rod to duplex (cone/rod) retinas. To explore whether nocturnal versus diurnal activity is responsible for constraints on molecular evolution and plays a role in visual opsin spectral tuning of colubrids, we carried out molecular evolution analyses of the visual opsin genes LWS, RH1, and SWS1 from 17 species and performed morphological analyses...
December 11, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/29228676/genes-with-mutation-significance-were-highly-associated-with-the-clinical-pattern-of-patients-with-breast-cancer
#12
Wan-Jun Ding, Tao Zeng, Li-Jun Wang, Hong-Bo Lei, Wei Ge, Zhi Wang
In the United States, breast cancer is the second leading cause of cancer death in women. Over the past 20 years, breast cancer incidence and mortality rates increased rapidly in developing regions. We aimed to identify the gene mutation patterns that associated with the clinical patterns, including survival status, histo-pathological classes and so forth, of breast cancer. We retrieved 1098 cases of the clinical information, and level-3 legacy data of mRNA expression level, protein expression data and mutation files from GDC data portal...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29226988/cns-high-grade-neuroepithelial-tumor-with-bcor-internal-tandem-duplication-a-comparison-with-its-counterparts-in-the-kidney-and-soft-tissue
#13
Yuka Yoshida, Sumihito Nobusawa, Satoshi Nakata, Mitsutoshi Nakada, Yoshiki Arakawa, Yohei Mineharu, Yasuo Sugita, Takako Yoshioka, Asuka Araki, Yuichiro Sato, Hideo Takeshima, Masahiko Okada, Akira Nishi, Tatsuya Yamazaki, Kenichi Kohashi, Yoshinao Oda, Junko Hirato, Hideaki Yokoo
Central nervous system high-grade neuroepithelial tumors with BCOR alteration (CNS HGNET-BCOR) are a recently reported rare entity, identified as a small fraction of tumors previously institutionally diagnosed as so-called CNS primitive neuroectodermal tumors. Their genetic characteristic is a somatic internal tandem duplication in the 3' end of BCOR (BCOR ITD), which has also been found in clear cell sarcomas of the kidney (CCSK) and soft tissue undifferentiated round cell sarcomas/primitive myxoid mesenchymal tumors of infancy (URCS/PMMTI), and these BCOR ITD-positive tumors have been reported to share similar pathological features...
December 11, 2017: Brain Pathology
https://www.readbyqxmd.com/read/29226269/evaluating-weathering-of-food-packaging-polyethylene-nano-clay-composites-release-of-nanoparticles-and-their-impacts
#14
Changseok Han, Amy Zhao, Eunice Varughese, E Sahle-Demessie
Nano-fillers are increasingly incorporated into polymeric materials to improve the mechanical, barrier or other matrix properties of nanocomposites used for consumer and industrial applications. However, over the life cycle, these nanocomposites could degrade due to exposure to environmental conditions, resulting in the release of embedded nanomaterials from the polymer matrix into the environment. This paper presents a rigorous study on the degradation and the release of nanomaterials from food packaging composites...
January 1, 2018: NanoImpact
https://www.readbyqxmd.com/read/29226065/challenges-and-opportunities-in-studying-the-epidemiology-of-ovarian-cancer-subtypes
#15
Jennifer Anne Doherty, Lauren Cole Peres, Chen Wang, Gregory P Way, Casey S Greene, Joellen M Schildkraut
Purpose of review: Only recently has it become clear that epithelial ovarian cancer (EOC) is comprised of such distinct histotypes--with different cells of origin, morphology, molecular features, epidemiologic factors, clinical features, and survival patterns-that they can be thought of as different diseases sharing an anatomical location. Herein, we review opportunities and challenges in studying EOC heterogeneity. Recent findings: The 2014 World Health Organization diagnostic guidelines incorporate accumulated evidence that high- and low-grade serous tumors have different underlying pathogenesis, and that, on the basis of shared molecular features, most high grade tumors, including some previously classified as endometrioid, are now considered to be high-grade serous...
September 2017: Current Epidemiology Reports
https://www.readbyqxmd.com/read/29224785/incongruence-between-molecules-and-morphology-a-seven-gene-phylogeny-of-dacini-fruit-flies-paves-the-way-for-reclassification-diptera-tephritidae
#16
Michael San Jose, Camiel Doorenweerd, Luc Leblanc, Norman Barr, Scott Geib, Daniel Rubinoff
Molecular and morphological research often suggest conflicting results. Selective pressure on certain morphologies can confound understanding of evolutionary relationships. Dacini is one of the most diverse tribes of tephritid flies and contains many economically important pest species. Their black and yellow patterned body markings are presumed to act as wasp mimicry, and the characters separating species and groups are limited and in some cases phenotypically plastic. The traditional taxonomy of the tribe is controversial because groupings are based on unique combinations of morphological characters without the use of cladistic methods, though recent phylogenetic and taxonomic analyses have resulted in significant changes to their taxonomy...
December 7, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29224275/-clinicopathologic-study-of-infiltrating-epitheliosis-of-the-breast
#17
X L Xu, X Y Tu, R H Shui, Y F Cheng, B H Yu, W T Yang
Objective: To evaluate the morphological and immunohistochemical features of infiltrating epitheliosis and its differential diagnosis. Methods: Nine consultation and routine cases of infiltrating epitheliosis diagnosed from January 2015 to December 2016 in Fudan University Shanghai Cancer Center were collected. All tissues were formalin-fixed paraffin-embedded and routinely HE stained. The HE slides were reviewed. Immunohistochemical staining of CKpan, CK7, CK19, CK5/6, CK14, p63, SMMHC, Calponin, ER, PR, HER2, Ki-67 and S-100 protein was performed using Ventana BenchMark automated immunostainer...
December 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29222591/dementia-with-lewy-bodies-and-parkinson-s-disease-dementia-current-concepts-and-controversies
#18
REVIEW
Kurt A Jellinger
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although sharing many clinical, neurochemical and morphological features, according to DSM-5, are two entities of major neurocognitive disorders with Lewy bodies of unknown etiology. Despite considerable clinical overlap, their diagnosis is based on an arbitrary distinction between the time of onset of motor and cognitive symptoms: dementia often preceding parkinsonism in DLB and onset of cognitive impairment after onset of motor symptoms in PDD...
December 8, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29222507/induced-unconventional-superconductivity-on-the-surface-states-of-bi2te3-topological-insulator
#19
Sophie Charpentier, Luca Galletti, Gunta Kunakova, Riccardo Arpaia, Yuxin Song, Reza Baghdadi, Shu Min Wang, Alexei Kalaboukhov, Eva Olsson, Francesco Tafuri, Dmitry Golubev, Jacob Linder, Thilo Bauch, Floriana Lombardi
Topological superconductivity is central to a variety of novel phenomena involving the interplay between topologically ordered phases and broken-symmetry states. The key ingredient is an unconventional order parameter, with an orbital component containing a chiral p x  + ip y wave term. Here we present phase-sensitive measurements, based on the quantum interference in nanoscale Josephson junctions, realized by using Bi2Te3 topological insulator. We demonstrate that the induced superconductivity is unconventional and consistent with a sign-changing order parameter, such as a chiral p x  + ip y component...
December 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/29222292/uncoding-the-genetic-heterogeneity-of-myelodysplastic-syndrome
#20
REVIEW
R Coleman Lindsley
Myelodysplastic syndrome (MDS) is a clinically heterogeneous disease characterized by functional impairment of hematopoiesis and abnormal bone marrow morphology. The type and severity of hematopoietic dysfunction in MDS are highly variable, and the kinetics of disease progression are difficult to predict. Genomic studies have shown that MDS is typically driven by a multistep somatic genetic process affecting a core set of genes. By definition, recurrent MDS driver mutations all drive clonal dominance, although they can have stereotyped positions in the clonal hierarchy or patterns of comutation association and exclusivity...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
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