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Shaoyun Zhang, Bin Xu, Qiang Huang, Huan Yao, Jinwei Xie, Fuxing Pei
There is no consensus as to whether drainage tube should be used and how long it should remain in use after primary total knee arthroplasty (TKA). As fast-track (FT) program has been implemented in TKA, whether drainage tube could be removed early, and the ideal timing for removal after FT primary TKA has been a new topic. The purpose of this prospective cohort study was to evaluate the safety and feasibility of early removal of drainage tube when FT program was implemented in primary TKA. A total of 101 patients undergoing FT primary TKA were prospectively allocated into three groups...
October 24, 2016: Journal of Knee Surgery
Shelley Gray
In this editorial, the Editor of Language, Speech, and Hearing Services in Schools (LSHSS) describes important changes coming to LSHSS and all ASHA journals and calls for readers to voice their opinion regarding important topics and formats they would like to see included in future LSHSS volumes.
October 24, 2016: Language, Speech, and Hearing Services in Schools
Fen Xue, Duanshu Li, Chaosu Hu, Zhuoying Wang, Xiayun He, Yi Wu
Poorly differentiated thyroid carcinoma (PDTC) is a rare and aggressive malignancy with high rates of invasion and distant metastasis. This study was to explore the ability of intensity-modulated radiotherapy (IMRT) combined with chemotherapy to manage unresectable PDTC. Between February 2011 and April 2012, 5 patients with unresectable PDTC were treated by IMRT at our institution and were included in this analysis. The median radiotherapy dose to the gross tumor volume (GTV) was 66 Gy/33 fractions/6.4 weeks...
October 20, 2016: Oncotarget
S C Cifuentes, E Frutos, R Benavente, V Lorenzo, J L González-Carrasco
This work deals with the mechanical characterization by depth-sensing indentation (DSI) of PLLA and PLDA composites reinforced with micro-particles of Mg (up to 15wt%), which is a challenging task since the indented volume must provide information of the bulk composite, i.e. contain enough reinforcement particles. The composites were fabricated by combining hot extrusion and compression moulding. Physico-chemical characterization by TGA and DSC indicates that Mg anticipates the thermal degradation of the polymers but does not compromise their stability during processing...
September 21, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Nicholas W Sterling, Guangwei Du, Mechelle M Lewis, Steven Swavely, Lan Kong, Martin Styner, Xuemei Huang
Cortical atrophy has been documented in both Parkinson's disease (PD) and healthy aging, but its relationship to changes in subcortical white matter is unknown. This was investigated by obtaining T1- and diffusion-weighted images from 76 PD and 70 controls at baseline and 18 and 36 months, from which cortical volumes and underlying subcortical white matter axial diffusivity (AD), radial diffusivity (RD), and fractional anisotropy (FA) were determined. Twelve of 69 cortical subregions had significant group differences, and for these, underlying subcortical white matter was explored...
September 28, 2016: Neurobiology of Aging
Ruoxi Wang, Dongju Zhang, Chengbu Liu
Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are highly toxic to humans and the environment. Developing efficient methods to detect or remove these pollutants is particularly important and urgent. Boron nitride nanotubes (BNNTs) with low dimension and high surface-to-volume ratio might be one of promising materials for the adsorption of PCDD/Fs. Here we present a density functional theory (DFT) study on the interaction of the pristine and Ni doped (8,0) single-walled BNNTs with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic congener among PCDD/F family...
October 21, 2016: Chemosphere
Dong-Hyun Choi, Seong-Ho Kang, Heesang Song
Platelets are essential for progression of atherosclerotic lesions, plaque destabilization, and thrombosis. They secrete and express many substances that are crucial mediators of coagulation, inflammation, and atherosclerosis. Mean platelet volume (MPV) is a precise measure of platelet size, and is routinely reported during complete blood count analysis. Emerging evidence supports the use of MPV as a biomarker predicting the risk of ischemic stroke in patients with atrial fibrillation, and as a guide for prescription of anticoagulation and rhythm-control therapy...
October 24, 2016: Korean Journal of Internal Medicine
Ulrike Herberg, Katharina Linden, Oliver Dewald, Eva Gatzweiler, Matthias Seehase, Georg Daniel Duerr, Jonas Dörner, Stephanie Kleppe, Dennis Ladage, Johannes Breuer
BACKGROUND: Pressure-volume loops (PVL) provide vital information regarding ventricular performance and pathophysiology in cardiac disease. Unfortunately, acquisition of PVL by conductance technology is not feasible in neonates and small children due to the available human catheter size and resulting invasiveness. The aim of the study was to validate the accuracy of PVL in small hearts using volume data obtained by real-time three-dimensional echocardiography (3DE) and simultaneously acquired pressure data...
2016: PloS One
B C C Khoo, J K Brown, R L Prince
OBJECTIVES: In recent years quantitative computed tomography (QCT) has allowed precise non-invasive, three dimensional, in vivo measurement of hip structure in large numbers of individuals. The effects of ageing on proximal femur structure are reported and implications for the prevention of hip prosthesis loosening and hip fracture considered. DESIGN, SETTING AND PARTICIPANTS: An observational cross-sectional study of proximal femur QCT in 719 unselected female European descent aged 20 to 89 years recruited from US and Australian populations...
2016: PloS One
Joelle Leonie Flueck, Fabienne Schaufelberger, Martina Lienert, Daniela Schäfer Olstad, Matthias Wilhelm, Claudio Perret NCT02083328.
2016: PloS One
Robert Froud, Shilpa Patel, Dévan Rajendran, Philip Bright, Tom Bjørkli, Rachelle Buchbinder, Sandra Eldridge, Martin Underwood
BACKGROUND: Increasing patient-reported outcome measures in the 1980s and 1990s led to the development of recommendations at the turn of the millennium for standardising outcome measures in non-specific low back pain (LBP) trials. Whether these recommendations impacted use is unclear. Previous work has examined citation counts, but actual use and change over time, has not been explored. Since 2011, there has been some consensus on the optimal methods for reporting back pain trial outcomes...
2016: PloS One
Jessica Chapman, Stephanie Marfurt, Julie Reid
This systematic review evaluates the effectiveness of delayed cord clamping in preterm infants on reducing postdelivery complications of anemia, hemodynamic instability, and the development of intraventricular hemorrhages. Interventions included varying durations of delayed cord clamping with and without cord milking as compared with immediate cord clamping, shorter delays in cord clamping, and delayed cord clamping without cord milking. A comprehensive search of randomized controlled trials, observational, cohort, and before-after studies was conducted between 1946 and 2015 in the electronic databases of Ovid MEDLINE, Embase, and Google Scholar...
October 2016: Journal of Perinatal & Neonatal Nursing
Sang Hyun Hwang, Jeong Won Lee, Ho Jin Cho, Kyung Sik Kim, Gi Hong Choi, Mijin Yun
PURPOSE: The aim of this article was to evaluate the prognostic value of metabolic tumor volume (MTV) and total lesion glycolysis (TLG) on preoperative F-FDG PET/CT for predicting intrahepatic recurrence-free survival (IHRFS), extrahepatic metastasis-free survival (EHMFS), and overall survival (OS) in patients with very early/early hepatocellular carcinoma (HCC). PATIENTS AND METHODS: We retrospectively enrolled 132 patients with very early/early HCC who underwent F-FDG PET/CT followed by surgery...
October 21, 2016: Clinical Nuclear Medicine
Ravindra Kumar Jha, Prasanta Kumar Guha
WS2 nanosheets have been synthesized by ultrasonication in a binary mixture of acetone and 2-propanol, with a volume ratio of 80:20. Hansen solubility parameters were taken into consideration as part of the process. These nanosheets have been characterized by electron microscopy, atomic force microscopy, and x-ray diffraction, along with spectroscopy such as ultraviolet-visible spectroscopy, Raman spectroscopy, and x-ray photoelectron spectroscopy. The nanosheets were further used as a sensing material to fabricate a humidity sensor on interdigitated aluminum electrodes, realized over Si/SiO2 substrate using a conventional photolithography technique...
October 24, 2016: Nanotechnology
Yongxin Guan, Yangyang Feng, Yanping Mu, Ling Fang, Huijuan Zhang, Yu Wang
Known as an excellent energy storage material, ZnMn2O4 has a wide range of applications in supercapacitors. In this report, a special sandwich-like structure of ZnMn2O4/C has been first designed and synthesized via a simple hydrothermal method and subsequent calcinations. The designed special sandwich-like structure can benefit ion exchange and remit the probable volume changes during a mass of electrochemical reactions. Furthermore, the porous carbon nanosheets, derived from low-cost glucose, can effectively increase ion flux...
October 24, 2016: Nanotechnology
Alexis Klengel, Patrick Stumpp, Steffen Klengel, Ina Böttger, Nadja Rönisch, Thomas Kahn
Purpose To compare single-shot echo-planar diffusion-weighted imaging-derived apparent diffusion coefficient (ADC) maps with fat-saturated (FS) proton density (PD)-weighted turbo spin-echo (TSE) imaging in the detection of bone marrow lesions (BMLs) after knee trauma. Materials and Methods Institutional review board approval was obtained from Leipzig University. Written informed consent was waived. Three radiologists retrospectively re-examined 97 consecutive patients with reported knee trauma who underwent 1...
October 24, 2016: Radiology
Imelda Ryona, Jack Henion
Despite many benefits including simple point-of-care sample collection, reduced costs, and simplified shipping and storage, dried blood spot (DBS) techniques have faced adoption resistance such as the hematocrit (Hct) effects and the established preference for bioanalysis of plasma rather than whole blood. One way to potentially circumvent these challenges is to adopt the concept of a dried plasma spot (DPS) technique. One approach to accomplishing this is through an on-card red blood cell (RBC) filtration to generate plasma from whole blood without the need for centrifugation...
October 24, 2016: Analytical Chemistry
Kimiko Aoki, Hiroyuki Tanaka, Makoto Ueki
When the tampering of a urine sample is suspected in doping control, personal identification of the sample needs to be determined by short tandem repeat (STR) analysis using DNA. We established a method for extracting DNA from urine samples stored at -20 °C without using any additives or procedures, which is consistent with how samples are required to be managed for doping control. The method, using the Puregene® Blood Core kit followed by NucleoSpin® gDNA Clean-up or NucleoSpin® gDNA Clean-up XS kit, does not need any special instrument and can provide a purified extract with high-quality DNA from up to 40 mL of urine suitable for STR analysis using an AmpFlSTR® Identifiler® PCR amplification kit...
October 24, 2016: Drug Testing and Analysis
Fereshteh Rahimi, Javad Mohammadnejad Arough, Mona Yaghoobi, Hadi Davoodi, Fatemeh Sepehri, Masood Amirabadizadeh
In this study, porous silicon (PSi) was utilized instead of prevalent polystyrene platforms and its capability in biomolecules screening was examined. Here, two types of porous structure, macroporous silicon (Macro-PSi) and mesoporous silicon (Meso-PSi) were produced on silicon wafers by electrochemical etching using different electrolytes. Moreover, both kinds of fresh and Oxidized PSi samples were investigated. Next, osteocalcin as biomarker of bone formation process was used as a model biomarker and the colorimetric detection was performed by competitive Enzyme-linked Immunosorbent Assay (ELISA)...
October 24, 2016: Biotechnology and Applied Biochemistry
Richard Baumgartner, William Cho, Alexandre Coimbra, Christopher Chen, Zaiqi Wang, Arie Struyk, Narayanaswamy Venketasubramanian, May Low, Cindy Gargano, Fuqiang Zhao, Donald Williams, Torsten Reese, Stephanie Seah, Dai Feng, Sonya Apreleva, Esben Petersen, Jeffrey L Evelhoch
PURPOSE: To present the testretest and contrast dose effect results of cerebral blood volume (CBV) functional MRI (fMRI) in healthy human volunteers using ferumoxytol (Feraheme), an ultrasmall-superparamagnetic iron oxide (USPIO) nanoparticle. MATERIALS AND METHODS: This was an open-label, two-period, fixed-sequence study in healthy young volunteers. In eight subjects, using a 3 Tesla field strength system, blood oxygen level dependent (BOLD) and CBV fMRI were acquired in response to a visual black-and-white checkboard stimulation paradigm using an escalating ferumoxytol dose design (250, 350, and 510 mg iron)...
October 24, 2016: Journal of Magnetic Resonance Imaging: JMRI
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