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https://www.readbyqxmd.com/read/29042021/fresnel-s-laws-ceteris-paribus
#1
Aaron Sidney Wright
This article is about structural realism, historical continuity, laws of nature, and ceteris paribus clauses. Fresnel's Laws of optics support Structural Realism because they are a scientific structure that has survived theory change. However, the history of Fresnel's Laws which has been depicted in debates over realism since the 1980s is badly distorted. Specifically, claims that J. C. Maxwell or his followers believed in an ontologically-subsistent electromagnetic field, and gave up the aether, before Einstein's annus mirabilis in 1905 are indefensible...
August 2017: Studies in History and Philosophy of Science
https://www.readbyqxmd.com/read/29027515/-a-boy-with-a-white-striped-knee-on-a-radiograph
#2
M G Mentink, R J P Weber, F H Jansen
A 10-year-old boy presented at the radiology department with pain in the right knee. Radiographs of the knee revealed dens metaphyseal bands and subchondral epiphyseal sclerosis as a result of periodic bisphosphonate administration for the treatment of Legg-Calvé-Perthes disease three years ago.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29021883/brodie-s-abscess-of-posterior-ilium-with-gluteal-syndrome-an-unusual-cause-of-paediatric-low-back-pain-a-case-report
#3
G Behera, M Poduval, D K Patro, S Sahoo
Brodie's abscess is a variety of subacute osteomyelitis with a long duration of presentation and intermittent pain. It usually involves the metaphyseal region of long bones of the lower limbs. Brodie's abscess of pelvic bone is very rare. Involvement of posterior ilium with gluteal syndrome is extremely unusual and can be easily missed or misdiagnosed. We present a 9-year old boy who reported to us with intermittent low back pain of three months duration without any other constitutional symptoms. Clinically, there was mild tenderness over the posterior ilium...
July 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29019753/imaging-of-pediatric-growth-plate-disturbances
#4
Jie C Nguyen, B Keegan Markhardt, Arnold C Merrow, Jerry R Dwek
The growth plates, or physes, are visible on virtually all images obtained in skeletally immature children. The proper function of these growth plates depends on an intricate balance between chondrocyte proliferation, which requires nourishment from the epiphyseal vessels, and chondrocyte death, which requires the integrity of the metaphyseal vessels. Therefore, injury to the growth plate (ie, direct insult) or vascular compromise on either side of the growth plate (ie, indirect insult) can cause growth plate dysfunction...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29016430/an-anatomic-and-radiographic-study-of-the-distal-tibial-epiphysis
#5
Cynthia V Nguyen, Janelle D Greene, Daniel R Cooperman, Raymond W Liu
BACKGROUND: Although the undulating shape of the distal tibial epiphysis is well recognized, its anatomic features have not been well quantified in the literature. To guide the placement of surgical implants about the distal tibial physis, we investigated the topographical anatomy of the distal tibial epiphysis and explored the ability of standard radiographs to visualize the physis. METHODS: We studied 30 cadaveric distal tibial epiphyses in specimens 3 to 14 years of age...
October 9, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28993616/bone-corticalization-requires-local-socs3-activity-and-is-promoted-by-androgen-action-via-interleukin-6
#6
Dae-Chul Cho, Holly J Brennan, Rachelle W Johnson, Ingrid J Poulton, Jonathan H Gooi, Brett A Tonkin, Narelle E McGregor, Emma C Walker, David J Handelsman, T J Martin, Natalie A Sims
Long bone strength is determined by its outer shell (cortical bone), which forms by coalescence of thin trabeculae at the metaphysis (corticalization), but the factors that control this process are unknown. Here we show that SOCS3-dependent cytokine expression regulates bone corticalization. Young male and female Dmp1Cre.Socs3 (f/f) mice, in which SOCS3 has been ablated in osteocytes, have high trabecular bone volume and poorly defined metaphyseal cortices. After puberty, male mice recover, but female corticalization is still impaired, leading to a lasting defect in bone strength...
October 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28975624/genesis-and-profanation-of-the-other-world-the-interpretation-of-dreams
#7
Leandro Drivet
This paper addresses Nietzsche's reflections on the phenomenon of dreams as a crucial precedent of Freud's Die Traumdeutung. The works of Nietzsche and Freud are scrutinized to establish and compare the most relevant aspects of their understanding of dreams. The philosophical impact of both accounts is assessed in terms of the transvaluation of religious and metaphysical values, which reveals three epistemological shifts: the replacement of Metaphysics by History/Genealogy (Nietzsche) and by Metapsychology (Freud), and the expansion of rationality beyond the limits of consciousness (Nietzsche and Freud)...
October 4, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28969746/giant-osteosarcoma-of-the-mandible
#8
Nilesh D Pardhe, Anshuman Jamdade, Manas Bajpai, Nilotpol Kashyap, Nikunj Mathur
Osteosarcoma is a rare primary malignant bone tumor with considerable variations not only in clinical and histologic appearance, but also in the course and prognosis of the disease. It mainly occurs in the metaphyseal region of long bones. Jaw osteosarcomas are relatively rare as compared to those occurring in long bones and share similar histopathologic features, but biologically behave in a different manner. Early diagnosis and complete resection of the lesion are necessary for better prognosis. This report highlights an aggressive and fatal case of mandibular osteosarcoma in a 23-year male patient, which, if diagnosed earlier, would have added some valuable years to the patient's life...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28965688/radiographic-changes-differ-between-two-different-short-press-fit-humeral-stem-designs-in-total-shoulder-arthroplasty
#9
Patrick J Denard, Matthew P Noyes, J Brock Walker, Yousef Shishani, Reuben Gobezie, Anthony A Romeo, Evan Lederman
BACKGROUND: The purpose of this study was to compare the radiographic changes of the humerus in the short term after total shoulder arthroplasty with two different short-stem humeral components. The hypothesis was that there would be no difference in radiographic changes or functional outcome based on component type. METHODS: A retrospective review was conducted of primary total shoulder arthroplasties performed with a short press-fit humeral component. Group A included a collarless humeral stem with an oval geometry and curved stem (Ascend or Ascend Flex; Wright Medical, Memphis, TN, USA)...
September 28, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28956091/strontium-ranelate-stimulates-trabecular-bone-formation-in-a-rat-tibial-bone-defect-healing-process
#10
C Lavet, G Mabilleau, D Chappard, R Rizzoli, P Ammann
Strontium ranelate treatment is known to prevent fractures. Here, we showed that strontium ranelate treatment enhances bone healing and affects bone cellular activities differently in intact and healing bone compartments: Bone formation was increased only in healing compartment, while resorption was reduced in healing and normal bone compartments. INTRODUCTION: Systemic administration of strontium ranelate (SrRan) accelerates the healing of bone defects; however, controversy about its action on bone formation remains...
September 28, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28940776/influence-of-collars-on-the-primary-stability-of-cementless-femoral-stems-a-finite-element-study-using-a-diverse-patient-cohort
#11
Rami M A Al-Dirini
For cementless femoral stems, there is debate as to whether a collar enhances primary stability and load transfer compared to collarless designs. Finite Element (FE) analysis has the potential to compare stem designs within the same cohort, allowing for subtle performance differences to be identified, if present. Subject-specific FE models of intact and implanted femora were run for a diverse cohort (21 males, 20 females; BMI 16.4-41.2 kg.m(-2) , age 50-80yrs). Collared and collarless versions of Corail® (DePuy Synthes) were sized and positioned using an automated algorithm that aligns the femoral/stem axes, preserves the head-centre location and maximises metaphyseal fit...
September 21, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28936109/metaphysical-resources-for-the-treatment-of-violence-the-self-action-distinction
#12
Alexandra Pârvan
No abstract text is available yet for this article.
September 2017: Philosophy, Psychiatry, & Psychology: PPP
https://www.readbyqxmd.com/read/28934543/long-term-results-of-intercalary-endoprosthetic-short-segment-fixation-following-extended-diaphysectomy
#13
Nicholas S Tedesco, Alexandra L Van Horn, Robert M Henshaw
Intercalary endoprosthetic reconstruction following diaphyseal resection of osseous tumors offers functional advantages through preservation of native joints adjacent to the resected defect. Use of such implants is restricted by the amount of bone available for stem fixation adjacent to the defect. This study aimed to determine whether short osseous segment fixation with acceptable outcomes and complication rate can be reliably achieved with a customized intercalary endoprosthesis following extended diaphysectomy...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28932487/intra-articular-fractures-of-the-distal-tibia-current-concepts-of-management
#14
REVIEW
Alexandre Sitnik, Aleksander Beletsky, Steven Schelkun
Results of the treatment of intra-articular fractures of the distal tibia have improved significantly during the last two decades.Recognition of the role of soft tissues has led to the development of a staged treatment strategy. At the first stage, joint-bridging external fixation and fibular fixation are performed. This leads to partial reduction of the distal tibial fracture and allows time for the healing of soft tissues and detailed surgical planning.Definitive open reduction and internal fixation of the tibial fracture is performed at a second stage, when the condition of the soft tissues is safe...
August 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28923958/multiscale-characterization-of-the-mineral-phase-at-skeletal-sites-of-breast-cancer-metastasis
#15
Frank He, Aaron E Chiou, Hyun Chae Loh, Maureen Lynch, Bo Ri Seo, Young Hye Song, Min Joon Lee, Rebecca Hoerth, Emely L Bortel, Bettina M Willie, Georg N Duda, Lara A Estroff, Admir Masic, Wolfgang Wagermaier, Peter Fratzl, Claudia Fischbach
Skeletal metastases, the leading cause of death in advanced breast cancer patients, depend on tumor cell interactions with the mineralized bone extracellular matrix. Bone mineral is largely composed of hydroxyapatite (HA) nanocrystals with physicochemical properties that vary significantly by anatomical location, age, and pathology. However, it remains unclear whether bone regions typically targeted by metastatic breast cancer feature distinct HA materials properties. Here we combined high-resolution X-ray scattering analysis with large-area Raman imaging, backscattered electron microscopy, histopathology, and microcomputed tomography to characterize HA in mouse models of advanced breast cancer in relevant skeletal locations...
September 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28923129/a-cinema-for-the-unborn-moving-pictures-mental-pictures-and-electra-sparks-s-new-thought-film-theory
#16
Patrick Ellis
In the 1910s, New York suffragette Electra Sparks wrote a series of essays in the Moving Picture News that advocated for cine-therapy treatments for pregnant women. Film was, in her view, the great democratizer of beautiful images, providing high-cultural access to the city's poor. These positive 'mental pictures' were important for her because, she claimed, in order to produce an attractive, healthy child, the mother must be exposed to quality cultural material. Sparks's championing of cinema during its 'second birth' was founded upon the premise of New Thought...
September 2017: British Journal for the History of Science
https://www.readbyqxmd.com/read/28923047/prepubertal-onset-of-slipped-capital-femoral-epiphysis-associated-with-hypothyroidism-a-case-report-and-literature-review
#17
Saori Kadowaki, Tomohiro Hori, Hideki Matsumoto, Kaori Kanda, Michio Ozeki, Yu Shirakami, Norio Kawamoto, Hidenori Ohnishi, Toshiyuki Fukao
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is a common hip disorder characterized by displacement of the capital femoral epiphysis from the metaphysic through the femoral epiphyseal plate. SCFE usually occurs during puberty, with obesity a common risk factor. We experienced a rare case of SCFE associated with hypothyroidism in a prepubescent patient who was not obese. CASE PRESENTATION: The patient was an 8-year-old boy suffering from bilateral SCFE with hypothyroidism...
September 18, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28920921/increased-intracellular-proteolysis-reduces-disease-severity-in-an-er-stress-associated-dwarfism
#18
Lorna A Mullan, Ewa J Mularczyk, Louise H Kung, Mitra Forouhan, Jordan Ma Wragg, Royston Goodacre, John F Bateman, Eileithyia Swanton, Michael D Briggs, Raymond P Boot-Handford
The short-limbed dwarfism metaphyseal chondrodysplasia type Schmid (MCDS) is linked to mutations in type X collagen, which increase ER stress by inducing misfolding of the mutant protein and subsequently disrupting hypertrophic chondrocyte differentiation. Here, we show that carbamazepine (CBZ), an autophagy-stimulating drug that is clinically approved for the treatment of seizures and bipolar disease, reduced the ER stress induced by 4 different MCDS-causing mutant forms of collagen X in human cell culture...
October 2, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28905738/extraskeletal-osteochondroma-within-the-iliopsoas-muscle-case-report
#19
Svetoslav Slavchev, Georgi P Georgiev
Osteochondromas, occurring usually in the metaphyses of long bones, are among the most frequent benign musculoskeletal neoplasms and both their sporadic and hereditary variants have been studied extensively. Extraskeletal osteochondromas, however, are much less common. They have been shown to arise near joints or synovial spaces of feet, hands, or bursae. Herein, we present a very rare case of an extraskeletal osteochondroma within the iliopsoas muscle.
2017: SICOT-J
https://www.readbyqxmd.com/read/28902435/longitudinal-effects-of-single-hindlimb-radiation-therapy-on-bone-strength-and-morphology-at-local-and-contralateral-sites
#20
Megan E Oest, Connor G Policastro, Kenneth A Mann, Nicholas D Zimmerman, Timothy A Damron
Radiation therapy (RTx) is associated with increased risk for late-onset fragility fractures in bone tissue underlying the radiation field. Bone tissue outside the RTx field is often selected as a "normal" comparator tissue in clinical assessment of fragility fracture risk, but the robustness of this comparison is limited by an incomplete understanding of the systemic effects of local radiotherapy. In this study, a mouse model of limited field irradiation was used to quantify longitudinal changes in local (irradiated) and systemic (non-irradiated) femurs with respect to bone density, morphology, and strength...
September 13, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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