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https://www.readbyqxmd.com/read/28431104/the-potential-overlapping-populations-for-treatment-with-belimumab-and-rituximab-using-current-nhs-england-and-national-institute-for-health-and-care-excellence
#1
Eoghan M McCarthy, Emily Sutton, Stephanie Nesbit, Ben Parker, David Jayne, Bridget Griffiths, David A Isenberg, Anisur Rahman, Caroline Gordon, David P D'Cruz, Benjamin Rhodes, Peter Lanyon, Edward M Vital, Chee-Seng Yee, Christopher J Edwards, Lee-Suan Teh, Mohammed Akil, Neil J McHugh, Asad Zoma, Ian N Bruce
No abstract text is available yet for this article.
April 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/28431038/dietary-exposure-to-emulsifiers-and-detergents-and-the-prevalence-of-cardiovascular-disease
#2
Jonathan M Rhodes
No abstract text is available yet for this article.
April 18, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28430252/measuring-spatiotemporal-ultrafast-field-structures-of-pulses-from-multimode-optical-fibers
#3
Zhe Guang, Michelle Rhodes, Rick Trebino
Ultrashort pulses emerging from multimode optical fibers are spatiotemporally complex, because inside these fibers the modes have different spatial intensity patterns and experience different propagation velocities and dispersions. To determine the spatiotemporal field from multimode fibers, we applied a technique for the complete measurement of the output pulses called a spatially and temporally resolved intensity and phase evaluation device: full information from a single hologram. It yields the complete electric field over space and time from multiple digital holograms, simultaneously recorded at different frequencies on a single camera frame...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430066/cautions-for-extending-fecal-microbiota-transplantation-to-other-therapeutic-uses
#4
Rosamond Rhodes, Henry Sacks
No abstract text is available yet for this article.
May 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28430065/ethical-issues-in-fecal-microbiota-transplantation-in-practice
#5
Yonghui Ma, Jiayu Liu, Catherine Rhodes, Yongzhan Nie, Faming Zhang
Fecal microbiota transplantation (FMT) has demonstrated efficacy and is increasingly being used in the treatment of patients with recurrent Clostridium difficile infection. Despite a lack of high-quality trials to provide more information on the long-term effects of FMT, there has been great enthusiasm about the potential for expanding its applications. However, FMT presents many serious ethical and social challenges that must be addressed as part of a successful regulatory policy response. In this article, we draw on a sample of the scientific and bioethics literatures to examine clusters of ethical and social issues arising in five main areas: (1) informed consent and the vulnerability of patients; (2) determining what a "suitable healthy donor" is; (3) safety and risk; (4) commercialization and potential exploitation of vulnerable patients; and (5) public health implications...
May 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28427323/detection-of-qtl-for-traits-related-to-adaptation-to-sub-optimal-climatic-conditions-in-chickens
#6
Ching-Yi Lien, Michèle Tixier-Boichard, Shih-Wen Wu, Woei-Fuh Wang, Chen Siang Ng, Chih-Feng Chen
BACKGROUND: Growth traits can be used as indicators of adaptation to sub-optimal conditions. The current study aimed at identifying quantitative trait loci (QTL) that control performance under variable temperature conditions in chickens. METHODS: An F2 population was produced by crossing the Taiwan Country chicken L2 line (selected for body weight, comb area, and egg production) with an experimental line of Rhode Island Red layer R- (selected for low residual feed consumption)...
April 20, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/28426771/correction-a-systematic-review-of-rodent-pest-research-in-afro-malagasy-small-holder-farming-systems-are-we-asking-the-right-questions
#7
Lourens H Swanepoel, Corrie M Swanepoel, Peter R Brown, Seth J Eiseb, Steven M Goodman, Mark Keith, Frikkie Kirsten, Herwig Leirs, Themb'alilahlwa A M Mahlaba, Rhodes H Makundi, Phanuel Malebane, Emil F von Maltitz, Apia W Massawe, Ara Monadjem, Loth S Mulungu, Grant R Singleton, Peter J Taylor, Voahangy Soarimalala, Steven R Belmain
[This corrects the article DOI: 10.1371/journal.pone.0174554.].
2017: PloS One
https://www.readbyqxmd.com/read/28426301/small-group-randomized-controlled-trial-to-increase-condom-use-and-hiv-testing-among-hispanic-latino-gay-bisexual-and-other-men-who-have-sex-with-men
#8
Scott D Rhodes, Jorge Alonzo, Lilli Mann, Eunyoung Y Song, Amanda E Tanner, Jorge Elias Arellano, Rodrigo Rodriguez-Celedon, Manuel Garcia, Arin Freeman, Beth A Reboussin, Thomas M Painter
OBJECTIVES: To evaluate the HOLA en Grupos intervention, a Spanish-language small-group behavioral HIV prevention intervention designed to increase condom use and HIV testing among Hispanic/Latino gay, bisexual, and other men who have sex with men. METHODS: In 2012 to 2015, we recruited and randomized 304 Hispanic/Latino men who have sex with men, aged 18 to 55 years in North Carolina, to the 4-session HOLA en Grupos intervention or an attention-equivalent general health education comparison intervention...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28424678/microbial-and-isotopic-evidence-for-methane-cycling-in-hydrocarbon-containing-groundwater-from-the-pennsylvania-region
#9
Adrien Vigneron, Andrew Bishop, Eric B Alsop, Kellie Hull, Ileana Rhodes, Robert Hendricks, Ian M Head, Nicolas Tsesmetzis
The Pennsylvania region hosts numerous oil and gas reservoirs and the presence of hydrocarbons in groundwater has been locally observed. However, these methane-containing freshwater ecosystems remain poorly explored despite their potential importance in the carbon cycle. Methane isotope analysis and analysis of low molecular weight hydrocarbon gases from 18 water wells indicated that active methane cycling may be occurring in methane-containing groundwater from the Pennsylvania region. Consistent with this observation, multigenic qPCR and gene sequencing (16S rRNA genes, mcrA, and pmoA genes) indicated abundant populations of methanogens, ANME-2d (average of 1...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28424254/a-european-multicentre-study-on-the-analytical-performance-of-the-veris-hiv-1-assay
#10
Patrick Braun, Rafael Delgado, Monica Drago, Diana Fanti, Hervé Fleury, Jörg Hofmann, Jacques Izopet, Ulrich Kalus, Alessandra Lombardi, MaAngeles Marcos, Davide Mileto, Karine Sauné, Siobhan O'Shea, Alfredo Pérez-Rivilla, John Ramble, Pascale Trimoulet, Jordi Vila, Duncan Whittaker, Alain Artus, Daniel Rhodes
The analytical performance of the VERIS HIV-1 Assay for use on the new, fully automated Beckman Coulter DxN VERIS Molecular Diagnostics System(¥) was evaluated at 10 European Virology laboratories. Precision, analytical sensitivity, performance with negative samples, linearity, and performance with HIV-1 Groups/Subtypes were evaluated. Precision for the 1 mL assay showed an SD of 0.14 log10 cp/mL or less and CV ≤6.1% for each level tested. The 0.175 mL assay showed an SD of 0.17 log10 cp/mL or less and CV ≤5...
April 19, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28422904/a-comparison-of-prognosis-calculators-for-geriatric-trauma-a-p-a-l-li-a-t-e-consortium-study
#11
Tarik D Madni, Akpofure Peter Ekeh, Scott C Brakenridge, Karen J Brasel, Bellal Joseph, Kenji Inaba, Brandon R Bruns, Jeffrey D Kerby, Joseph Cuschieri, M Jane Mohler, Paul A Nakonezny, Audra Clark, Jonathan Imran, Steven E Wolf, M Elizabeth Paulk, Ramona L Rhodes, Herb A Phelan
BACKGROUND: The nine-center PALLIATE consortium has validated the Geriatric Trauma Outcome Score (GTOS) as a prognosis calculator for injured elders. We compared GTOS' performance to that of the Trauma Injury Severity Score (TRISS) in a multicenter sample. METHODS: Three PALLIATE centers not submitting subjects to the GTOS validation study identified subjects aged 65 to 102 yrs admitted from 2000-2013. GTOS was specified using the formula [GTOS = age + (ISS x 2...
April 18, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28422583/game-simulation-drill-design-alters-the-speed-profiles-of-wheelchair-rugby-players
#12
James M Rhodes, Barry S Mason, Thomas A W Paulson, Victoria L Goosey-Tolfrey
PURPOSE: This study examined the speed profiles of elite wheelchair rugby (WCR) players during game-simulation training drills of differing player number and shot-clock regulations. A secondary aim was to determine whether the profiles were further influenced by players classification. METHODS: Eight elite WCR players (low-point n = 3; high-point n = 5) were monitored using a radio-frequency based, indoor tracking system during training sessions over a 5-month period...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28415853/promoting-parent-and-child-physical-activity-together-elicitation-of-potential-intervention-targets-and-preferences
#13
Ryan E Rhodes, Clarise Lim
Promoting physical activities that involve both parents and their children would be very useful to the improved health and well-being of families, yet coactivity interventions have been particularly unsuccessful in past research. The purpose of this study was to elicit the salient parental beliefs about coactivity framed through theory of planned behavior in order to inform future intervention content. A representative sample of Canadian parents ( N = 483) with children aged 6 to 14 years completed belief elicitation measures of theory of planned behavior, as well as coactivity and program preferences...
April 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28414859/source-receptor-probability-of-atmospheric-long-distance-dispersal-of-viruses-to-israel-from-the-eastern-mediterranean-area
#14
Z Klausner, E Klement, E Fattal
Viruses that affect the health of humans and farm animals can spread over long distances via atmospheric mechanisms. The phenomenon of atmospheric long-distance dispersal (LDD) is associated with severe consequences because it may introduce pathogens into new areas. The introduction of new pathogens to Israel was attributed to LDD events numerous times. This provided the motivation for this study which is aimed to identify all the locations in the eastern Mediterranean that may serve as sources for pathogen incursion into Israel via LDD...
April 16, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28414360/visualizing-spatiotemporal-pulse-propagation-first-order-spatiotemporal-couplings-in-laser-pulses
#15
Michelle Rhodes, Zhe Guang, Jerrold Pease, Rick Trebino
Even though a general theory of first-order spatiotemporal couplings exists in the literature, it is often difficult to visualize how these distortions affect laser pulses. In particular, it is difficult to show the spatiotemporal phase of pulses in a meaningful way. Here, we propose a general solution to plotting the electric fields of pulses in three-dimensional space that intuitively shows the effects of spatiotemporal phases. The temporal phase information is color-coded using spectrograms and color response functions, and the beam is propagated to show the spatial phase evolution...
April 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/28410170/patients-and-health-care-providers-opinions-on-a-supportive-health-app-during-breast-cancer-treatment-a-qualitative-evaluation
#16
Danny A Young-Afat, Carla H van Gils, David J Bruinvels, Carmen C van der Pol, Arjen J Witkamp, Sieta Sijtsema, Yvette Jonasse, Rhodé M Bijlsma, Margreet G Ausems, Annelies M Bos, Desirée H van den Bongard, Helena M Verkooijen
BACKGROUND: Health apps are increasingly being used in clinical care and may hold significant theoretical potential. However, they are often implemented in clinical care before any research has been done to confirm actual benefits for patients, physicians, and researchers. OBJECTIVE: This study aimed to explore experiences of patients and health care providers with the use of a supportive breast cancer app during the first 6 months following diagnosis, in terms of benefits for clinical practice and research purposes...
June 7, 2016: JMIR Cancer
https://www.readbyqxmd.com/read/28408544/cost-and-outcome-of-behavioural-activation-versus-cognitive-behavioural-therapy-for-depression-cobra-a-qualitative-process-evaluation
#17
Katie Finning, David A Richards, Lucy Moore, David Ekers, Dean McMillan, Paul A Farrand, Heather A O'Mahen, Edward R Watkins, Kim A Wright, Emily Fletcher, Shelley Rhodes, Rebecca Woodhouse, Faye Wray
OBJECTIVE: To explore participant views on acceptability, mechanisms of change and impact of behavioural activation (BA) delivered by junior mental health workers (MHWs) versus cognitive behavioural therapy (CBT) delivered by professional psychotherapists. DESIGN: Semistructured qualitative interviews analysed using a framework approach. PARTICIPANTS: 36 participants with major depressive disorder purposively sampled from a randomised controlled trial of BA versus CBT (the COBRA trial)...
April 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28408435/neurturin-and-a-glp-1-analogue-act-synergistically-to-alleviate-diabetes-in-zucker-diabetic-fatty-rats
#18
James L Trevaskis, Chester Bittencourt Sacramento, Hani Jouihan, Safina Ali, John Le Lay, Stephanie Oldham, Nicholas Bhagroo, Brandon B Boland, Jennifer Cann, Yuan Chang, Terrence O'Day, Victor Howard, Christina Reers, Maria Sorhede Winzell, David M Smith, Michael Feigh, Pernille Barkholt, Kay Schreiter, Matthias Austen, Uwe Andag, Simon Thompson, Lutz Jermutus, Matthew P Coghlan, Joseph Grimsby, Cord Dohrmann, Christopher J Rhodes, Cristina M Rondinone, Arun Sharma
Neurturin (NRTN), a member of the glial-derived neurotrophic factor (GDNF) family, was identified from an embryonic chicken pancreatic cDNA library in a screen for secreted factors. Here, we assessed the potential antidiabetic activities of NRTN relative to liraglutide, a GLP-1 receptor agonist, in Zucker diabetic fatty (ZDF) rats. Subcutaneous administration of NRTN to 8-week-old male ZDF rats prevented the development of hyperglycemia and improved metabolic parameters similar to liraglutide. NRTN treatment increased pancreatic insulin content and β-cell mass, and prevented deterioration of islet organization...
April 13, 2017: Diabetes
https://www.readbyqxmd.com/read/28407650/insurance-coverage-and-utilization-at-a-sexually-transmitted-disease-clinic-in-a-medicaid-expansion-state
#19
Madeline C Montgomery, Julia Raifman, Amy S Nunn, Thomas Bertrand, A Ziggy Uvin, Theodore Marak, Jaime Comella, Alexi Almonte, Philip A Chan
BACKGROUND: In Rhode Island, the Patient Protection and Affordable Care Act has led to over 95% of the state's population being insured. We evaluated insurance coverage and barriers to insurance use among patients presenting for services at the Rhode Island sexually transmitted disease (STD) clinic. METHODS: We analyzed factors associated with insurance coverage and utilization among patients presenting for STD services between July and December 2015. RESULTS: A total of 692 patients had insurance information available; of those, 40% were uninsured...
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28407645/designing-human-immunodeficiency-virus-counselling-and-testing-services-to-maximize-uptake-among-high-school-learners-in-south-africa-what-matters
#20
Michael Strauss, Gavin George, Bruce Rhodes
BACKGROUND: Increasing human immunodeficiency virus (HIV) testing in South Africa is vital for the HIV response. Targeting young people is important as they become sexually active and because HIV risk rapidly increases as youth enter their 20s. This study aims to increase the understanding of high school learners' preferences regarding the characteristics of HIV testing service delivery models and to inform policy makers and implementers regarding potential barriers to and facilitators of HIV testing...
May 2017: Sexually Transmitted Diseases
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