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Katelyn Brinegar, Ali K Yetisen, Sun Choi, Emily Vallillo, Guillermo U Ruiz-Esparza, Anand M Prabhakar, Ali Khademhosseini, Seok-Hyun Yun
The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from basic research to translational medicine. In our analyses, we evaluated the patent landscape of gene-editing technologies and found that in comparison to earlier gene-editing techniques, CRISPR has gained significant traction and this has established dominance...
January 18, 2017: Critical Reviews in Biotechnology
Sally Carlton, Colleen E Mills
This paper seeks to contribute to understanding of the factors associated with an effective emergent emergency response organisation and to provide new insights into this understudied area. It examines, through an analysis of a range of textual resources, the emergence and re-emergence of the Student Volunteer Army (SVA) during the devastating earthquakes in Canterbury, New Zealand, in 2010-11. This evaluation is conducted in relation to the four key features of an effective emergency response organisation: adaptability; direction; leadership; and communication...
January 17, 2017: Disasters
Annamaria Di Fabio, Ornella Bucci, Alessio Gori
This article evaluates the psychometric properties of a new measure for assessing the constructs of entrepreneurship, leadership, and professionalism, from an integrated point of view, the High Entrepreneurship, Leadership and Professionalism Questionnaire (HELP-Q). Exploratory factor analysis indicated a factor structure with three principal dimensions, and confirmatory factor analysis and goodness of fit indices indicated a good fit of the model to the data. All the dimensions showed good values of internal consistency...
2016: Frontiers in Psychology
V Sashi Kumar, V K Paul, K Sathasivam
The care of small and sick neonates requires biomedical technologies, such as devices that can keep babies warm (radiant warmers and incubators), resuscitate (self-inflating bags), track growth (weighing scales), treat jaundice (phototherapy units) and provide oxygen or respiratory support (hoods, continuous positive airway pressure (CPAP) devices and ventilators). Until the 1990s, most of these products were procured through import at a high cost and with little maintenance support. Emerging demand and an informal collaboration of neonatologists, engineers and entrepreneurs has led to the production of good quality equipment of several high-volume categories at affordable cost in India...
December 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Edna Cadmus, Mary L Johansen, Phyllis Arn Zimmer, David L Knowlton
There is an unprecedented opportunity to move advanced practice nurses (APNs) into primary care settings at a steady rate over the next 5 to 8 years. In addition, the opportunity for nurse-owned or nurse-led practices has never been greater. However, many APNs currently work in a structured environment where the employer focuses on the business aspects of the practice and the APN focuses primarily on clinical care. Often APNs are unaware of the entrepreneurial contribution they make to the practice. A Needs Assessment Survey was developed to better understand business and practice management knowledge and skills of APNs in New Jersey...
January 2017: Nursing Administration Quarterly
Mohammad Reza Dehghanzadeh, Golrasteh Kholasehzadeh, Masoumeh Birjandi, Ensieh Antikchi, Mohamad Reza Sobhan, Hossein Neamatzadeh
Nurses are full partners with other health care professionals. Until fairly recently the scope of nurses potential in entrepreneurship has not been widely recognized. The present study tries to evaluate entrepreneurship psychological characteristics among nurses. The survey instrument included scales measuring entrepreneurship psychological characteristics including locus of control, need for achievement, risk taking propensity, ambiguity tolerance, and innovation, among nurses in the Shahid Sadoughi Hospital, Yazd, Iran in 2013...
September 2016: Acta Medica Iranica
Christian E Weller, Jeffrey B Wenger, Benyamin Lichtenstein, Carolyn Arcand
PURPOSE OF THE STUDY: Amid insufficient retirement savings and the growing need to work longer, it is important to understand why self-employment, especially entrepreneurship, has grown among older households. Older households may have been pushed into entrepreneurship by the growing risks of wage-and-salary employment as wages and jobs have become less stable. Alternatively, older households may have been pulled into entrepreneurship as the associated risks have declined, for instance, due to greater opportunities to diversify income away from risky business income...
November 3, 2016: Gerontologist
Pushkar S Joshi, Kunal K Ghosh
In this era of technology-driven global neuroscience initiatives, the role of the neurotechnology industry remains woefully ambiguous. Here, we explain why industry is essential to the success of these global initiatives, and how it can maximize the scientific impact of these efforts by (1) scaling and ultimately democratizing access to breakthrough neurotechnologies, and (2) commercializing technologies as part of integrated, end-to-end solutions that accelerate neuroscientific discovery.
November 2, 2016: Neuron
P W Handayani, A N Hidayanto, Dumilah Ayuningtyas, Indra Budi
The Hospital Information System (HIS) could help hospitals as a public entity to provide optimal health services. One of the main challenges of HIS implementation is an institutional change. Using institutional theory as the analytical lens, this study aims to explain the institutionalization of HIS as an instance of e-health initiatives in Indonesia. Furthermore, this paper aims for hospital management and researchers to improve the understanding of the social forces that influence hospital personnel's HIS acceptance within an organizational context...
November 2016: International Journal of Medical Informatics
F Zhong, W Tang, W Cheng, P Lin, Q Wu, Y Cai, S Tang, L Fan, Y Zhao, X Chen, J Mao, G Meng, J D Tucker, H Xu
OBJECTIVES: HIV self-testing (HIVST) offers an opportunity to increase HIV testing among people not reached by facility-based services. However, the promotion of HIVST is limited as a consequence of insufficient community engagement. We built a social entrepreneurship testing (SET) model to promote HIVST linkage to care among Chinese men who have sex with men (MSM) in Guangzhou. METHODS: The SET model includes a few key steps. Each participant first completed an online survey, and paid a US$23 (refundable) deposit to receive an HIVST kit and a syphilis self-testing (SST) kit...
September 7, 2016: HIV Medicine
Alireza Nikbakht-Nasrabadi, Maryam Shabany-Hamedan
BACKGROUND: Increasing hospital costs and its social and cultural problems has led to the idea of providing healthcare services at home. Because of infrastructural and implementation problems, providing healthcare at home in Iran has not been initiated yet. Therefore, this study set out to elaborate the need for a comprehensive system in order to provide this service in Iran. METHODS: All articles published in indexing sites with the defined keywords in English or Farsi were gathered...
July 2016: Iranian Journal of Public Health
Quan Hoang Vuong
This paper presents new results obtained from investigating the data from a 2015 Vietnamese entrepreneurs' survey, containing 3071 observations. Evidence from the estimations using multinomial logits was found to support relationships between several sociocultural factors and entrepreneurship-related performance or traits. Specifically, those relationships include: (a) Active participation in entrepreneurs' social networks and reported value of creativity; (b) CSR-willingness and reported entrepreneurs' perseverance; (c) Transforming of sociocultural values and entrepreneurs' decisiveness; and, (d) Lessons learned from others' failures and perceived chance of success...
2016: SpringerPlus
Devin Bunten, Stephan Weiler, Stephan Weiler, Sammy Zahran
We examine the contribution to economic growth of entrepreneurial "marketplace information" within a regional endogenous growth framework. Entrepreneurs are posited to provide an input to economic growth through the information revealed by their successes and failures. We empirically identify this information source with the regional variation in establishment births and deaths, which create geographic information asymmetries that influence subsequent entrepreneurial activity and economic growth. We find that local establishment birth and death rates are significantly and positively correlated with subsequent entrepreneurship for US counties...
September 2015: Journal of Regional Science
Joan Boada-Grau, José Carlos Sánchez-García, Eric Viardot, Maria Boada-Cuerva, Andreu Vigil-Colet
Entrepreneurship is linked to the perception of opportunities, to orientation, to attitudes, to the fear of failure and to entrepreneurial motivations. Entrepreneurial orientation is a fundamental construct for understanding the phenomenon of entrepreneurship. What is more, it is multidimensional and has attracted considerable attention from researchers in recent years. The objective of this study was to adapt the original 12-item English scale to Spanish and to analyze its psychometric properties. The participants in the present study were 925 Spanish employees (48...
July 25, 2016: Spanish Journal of Psychology
Rosa M Muñoz, Jesús D Sánchez de Pablo, Isidro Peña, Yolanda Salinero
The main purpose of this paper is to provide an understanding, within the field of corporate entrepreneurship, of the various factors that enable technology entrepreneurship in established firms and its principal effects on customers and society. The paper reports on a case study regarding technology entrepreneurship in a Spanish company whose activity is pharmaceutical distribution. This company has been able to overcome the consequences of the worldwide crisis and start an innovative process which includes the installation of new information technology (IT) and an investment of 6 million Euros...
2016: Frontiers in Psychology
James Fujimoto, Eric Swanson
This review was written for the special issue of IOVS to describe the history of optical coherence tomography (OCT) and its evolution from a nonscientific, historic perspective. Optical coherence tomography has become a standard of care in ophthalmology, providing real-time information on structure and function - diagnosing disease, evaluating progression, and assessing response to therapy, as well as helping to understand disease pathogenesis and create new therapies. Optical coherence tomography also has applications in multiple clinical specialties, fundamental research, and manufacturing...
July 1, 2016: Investigative Ophthalmology & Visual Science
Lauren Tingey, Francene Larzelere-Hinton, Novalene Goklish, Allison Ingalls, Todd Craft, Feather Sprengeler, Courtney McGuire, Allison Barlow
American Indian (AI) adolescents suffer the largest disparities in substance use and suicide. Predominating prevention models focus primarily on risk and utilize deficit-based approaches. The fields of substance use and suicide prevention research urge for positive youth development frameworks that are strength based and target change at individual and community levels. Entrepreneurship education is an innovative approach that reflects the gap in available programs. This paper describes the development and evaluation of a youth entrepreneurship education program in partnership with one AI community...
2016: American Indian and Alaska Native Mental Health Research: the Journal of the National Center
Damir Ljuboja, Brian W Powers, Benjamin Robbins, Robert Huckman, Krishnan Yeshwant, Sachin H Jain
There has been substantial growth in the number of physicians pursing Master of Business Administration (MBA) degrees over the past decade, but there is continuing debate over the utility of these programs and the career outcomes of their graduates. The authors analyzed the clinical and professional activities of a large cohort of physician-MBAs by gathering information on 206 physician graduates from the Harvard Business School MBA program who obtained their degrees between 1941 and 2014. Key outcome measures that were examined include medical specialty, current professional activity, and clinical practice...
2016: American Journal of Managed Care
Marian Altman, Debbie Brinker
No abstract text is available yet for this article.
July 2016: Nursing Management
Maria Jacobs, Liesbeth Boersma, Frits V Merode, Andre Dekker, Frank Verhaegen, Luc Linden, Philippe Lambin
OBJECTIVE: To study the efficiency of research implementation in a large radiotherapy institute, in either an internal review board-approved clinical trial or clinical routine. METHODS: Scientific publications of the institute were listed. We asked clinicians from tumour expert groups whether the study had been implemented yet in a clinical trial or in clinical practice and which facilitators or barriers were relevant. An independent investigator verified all results...
June 27, 2016: British Journal of Radiology
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