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https://www.readbyqxmd.com/read/29022036/a-case-of-bilateral-atypical-ulnar-fractures-with-bisphosphonate-therapy-in-a-walking-aided-elderly
#1
Michael Gj Yam, Ernest Bk Kwek
No abstract text is available yet for this article.
September 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28990014/atypical-root-resorption-following-root-fractures-in-primary-teeth
#2
Ok Hyung Nam, Mi Sun Kim, Gyu-Tae Kim, Sung Chul Choi
Atypical root resorption (ARR) is the condition of a superficial and circumferential resorption process along the lateral and/or apical root surface of a primary maxillary incisor. This case series demonstrates longitudinal observations of six patients with atypical root resorption following root-fractured primary incisors. The characteristics of atypical root resorption were different from pathologic root resorption.
October 6, 2017: Quintessence International
https://www.readbyqxmd.com/read/28982480/location-of-atypical-femoral-fracture-can-be-determined-by-tensile-stress-distribution-influenced-by-femoral-bowing-and-neck-shaft-angle-a-ct-based-nonlinear-finite-element-analysis-model-for-the-assessment-of-femoral-shaft-loading-stress
#3
Yoto Oh, Koji Fujita, Yoshiaki Wakabayashi, Yoshiro Kurosa, Atsushi Okawa
INTRODUCTION: Loading stress due to individual variations in femoral morphology is thought to be strongly associated with the pathogenesis of atypical femoral fracture (AFF). In Japan, studies on AFF regarding pathogenesis in the mid-shaft are well-documented and a key factor in the injury is thought to be femoral shaft bowing deformity. Thus, we developed a CT-based finite element analysis (CT/FEA) model to assess distribution of loading stress in the femoral shaft. PATIENTS AND METHODS: A multicenter prospective study was performed at 12 hospitals in Japan from August 2015 to February 2017...
September 27, 2017: Injury
https://www.readbyqxmd.com/read/28976439/is-atypical-bisphosphonate-treatment-response-a-risk-factor-for-atypical-femoral-fracture-commentary-on-an-article-by-kyung-jae-lee-md-et-al-t-score-discordance-of-bone-mineral-density-in-patients-with-atypical-femoral-fracture
#4
https://www.readbyqxmd.com/read/28976433/t-score-discordance-of-bone-mineral-density-in-patients-with-atypical-femoral-fracture
#5
Kyung-Jae Lee, Byung-Woo Min, Kwang-Soon Song, Ki-Cheor Bae, Chul-Hyun Cho, Si-Wook Lee
BACKGROUND: Although atypical femoral fracture (AFF) occurs more frequently in patients taking bisphosphonates and longer treatment is associated with higher risk, the causal relationship between AFF and bisphosphonates has not been established. Most patients with AFF have osteoporosis that is being treated with bisphosphonates, but we are not aware of any reports regarding the areal bone mineral density (aBMD) and discordance between the T-scores of the femur and spine in such patients...
October 4, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28966318/axillofemoral-bypass-markedly-improved-acute-decompensated-heart-failure-and-kidney-injury-in-a-patient-with-severely-calcified-stenosis-of-thoracoabdominal-aorta-atypical-aortic-coarctation
#6
Masato Ishizuka, Shintaro Yamada, Sonoko Maemura, Keisuke Yamamoto, Masataka Takizawa, Hiroki Uozumi, Sachito Minegishi, Jotaro Kobayashi, Hiroshi Ikenouchi
Atypical aortic coarctation (AAC) has been reported to occur anywhere along the aorta, except for the ascending aorta. The associated symptoms include hypotension in the lower half of the body, secondary hypertension in the upper half of the body, and heart failure. Here we present an 80-year-old Asian woman complaining of progressive exertional dyspnea. She was diagnosed with acute decompensated heart failure and kidney injury due to severely calcified stenosis of the thoracoabdominal aorta, the so called AAC...
September 30, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28942396/microbubble-enhanced-ultrasound-to-demonstrate-urethral-transection-in-a-case-of-penile-fracture
#7
Oliver Czarnecki, Conrad Brice von Stempel, Pippa Sangster, Miles Walkden
A 47-year-old man attended the emergency department following trauma during sexual intercourse after which he developed penile swelling and haematuria several hours later. A penile fracture was suspected but given the slightly atypical history, ultrasound was performed to look for a fracture. Given the history of haematuria, both a standard Doppler ultrasound and a microbubble-enhanced retrograde ultrasound urethrogram were performed. The Doppler confirmed the suspected diagnosis of penile fracture, and microbubble urethrogram demonstrated a urethral injury...
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28924690/lateral-fixation-an-alternative-surgical-approach-in-the-prevention-of-complete-atypical-femoral-fractures
#8
Mohammad Kharazmi, Karl Michaëlsson, Pär Hallberg, Jörg Schilcher
Little evidence is available on how to treat incomplete atypical fractures of the femur. When surgery is chosen, intramedullary nailing is the most common invasive technique. However, this approach is adopted from the treatment of other types of ordinary femoral fracture and does not aim to prevent the impending complete fracture by interrupting the mechanism underlying the pathology. We suggest a different surgical approach that intends to counteract the underlying biomechanical conditions leading to a complete atypical fracture and thus could be better suited in selected cases...
September 18, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28892457/romosozumab-or-alendronate-for-fracture-prevention-in-women-with-osteoporosis
#9
RANDOMIZED CONTROLLED TRIAL
Kenneth G Saag, Jeffrey Petersen, Maria Luisa Brandi, Andrew C Karaplis, Mattias Lorentzon, Thierry Thomas, Judy Maddox, Michelle Fan, Paul D Meisner, Andreas Grauer
BACKGROUND: Romosozumab is a monoclonal antibody that binds to and inhibits sclerostin, increases bone formation, and decreases bone resorption. METHODS: We enrolled 4093 postmenopausal women with osteoporosis and a fragility fracture and randomly assigned them in a 1:1 ratio to receive monthly subcutaneous romosozumab (210 mg) or weekly oral alendronate (70 mg) in a blinded fashion for 12 months, followed by open-label alendronate in both groups. The primary end points were the cumulative incidence of new vertebral fracture at 24 months and the cumulative incidence of clinical fracture (nonvertebral and symptomatic vertebral fracture) at the time of the primary analysis (after clinical fractures had been confirmed in ≥330 patients)...
October 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28883214/the-incidence-of-atypical-femoral-fractures-in-patients-with-rheumatic-disease-yamagata-prefectural-committee-of-atypical-femoral-fractures-yamacafe-study
#10
Yuya Takakubo, Daichi Ohta, Masaji Ishi, Juji Ito, Hiroharu Oki, Yasushi Naganuma, Tomohiro Uno, Akiko Sasaki, Takeru Akabane, Katsuyuki Dairaku, Shinichi Goto, Yasuo Goto, Yumiko Kanauchi, Shinji Kobayashi, Taku Nakajima, Keiji Masuda, Michiharu Matsuda, Nariyuki Mura, Kenji Takenouchi, Hiroyuki Tsuchida, Yasushi Onuma, Junichirou Shibuya, Mitsuyoshi Seino, Osamu Yamaguchi, Ken Hiragami, Yasuhiro Urayama, Takashi Furukawa, Shouta Okuda, Ken Ogura, Takeshi Nakamura, Kan Sasaki, Tsuneo Konta, Michiaki Takagi
Atypical femoral fractures (AFFs) have been reported to occur with minimal or spontaneous subtrochanteric and femoral shaft fractures with a characteristic transverse pattern, compared with typical femoral fractures in young patients with high-energy trauma. AFFs are related to long-term use of bisphosphonates (BPs), glucocorticoids and rheumatic diseases. We have estimated a blind analysis of AFFs in rheumatic patients receiving BPs and glucocorticoids ordinary over a long time in all Yamagata prefectural area through radiographic examination...
August 2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28878545/atraumatic-segmental-atypical-femur-fracture-secondary-to-bisphosphonate-use-a-case-report
#11
Andrew J Lovy, Diana Patterson, Laura Skeeles, Richard Ghillani, David Joseph, Yangguan Wu, Rohit Hasija
Atypical femur fractures as a result of long term bisphosphonate use are characterized by several unique radiographic features. We describe an atypical femur fracture treated by cephalomedullary nail with a previously undescribed segmental fracture pattern. Other than 1.5 years of bisphosphonate use the patient did not have any other risk factors known to cause atypical femur fractures. Judicious bisphosphonate use as well as increased awareness of the associated complications may help reduce the rate of bisphosphonate associated atypical femur fractures...
August 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28876272/intramedullary-nail-fixation-of-atypical-femur-fractures-with-bone-marrow-aspirate-concentrate-leads-to-faster-union-a-case-control-study-erratum
#12
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28844196/atypical-femoral-fracture-associated-with-bone-modifying-agent-for-bone-metastasis-of-breast-cancer-a-report-of-two-cases
#13
Daisuke Tateiwa, Hidetatsu Outani, Saya Iwasa, Yoshinori Imura, Takaaki Tanaka, Kazuya Oshima, Norifumi Naka, Nobuhito Araki
Atypical femoral fractures (AFFs) are recently observed as a complication of long-term bone-modifying agent (BMA; bisphosphonate or denosumab) therapy for bone metastases. We describe the cases of two women diagnosed with breast cancer who developed incomplete AFF associated with BMAs prescribed for bone metastases. Radiographs of their femurs revealed thickening of the lateral subtrochanteric cortex, and tomosynthesis revealed a visible fracture line in the thickened cortex. They were initially treated with conservative management; however, the incomplete fracture resulted in a complete fracture...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28796551/lateral-cortical-thickening-and-bone-heterogeneity-of-the-subtrochanteric-femur-measured-with-quantitative-ct-as-indicators-for-early-detection-of-atypical-femoral-fractures-in-long-term-bisphosphonate-users
#14
Seung Hyun Lee, Young Han Lee, Jin-Suck Suh
OBJECTIVE: The objective of our study was to compare subtrochanteric femur bone mineral density (BMD) and bone quality of long-term bisphosphonate (BP) users who sustained an atypical femoral fracture (AFF) with BP users who did not sustain a femoral fracture and BP-naïve patients with no history of femoral fracture using quantitative CT (QCT). MATERIALS AND METHODS: Fourteen female BP users with an AFF (mean age, 72.6 years; mean duration of BP use, 6.2 years; mean body mass index, 21...
October 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28781869/fragmented-central-venous-catheter-retained-for-years-with-minimal-symptoms
#15
Clancy W Mullan, Umair Tariq, Mark Goldin
Unidentified fractures of indwelling tunneled catheters are presumably rare and possibly underreported, but their consideration is important in patients with a history of catheter placement with otherwise unexplained, atypical chest pain.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28770350/surgical-outcomes-of-intramedullary-nailing-for-diaphyseal-atypical-femur-fractures-is-it-safe-to-modify-a-nail-entry-in-bowed-femur
#16
Ji Wan Kim, Hyunuk Kim, Chang-Wug Oh, Joon-Woo Kim, Oog-Jin Shon, Young-Soo Byun, Jung Jae Kim, Hyoung Keun Oh, Hiroaki Minehara, Kyu-Tae Hwang, Ki Chul Park
INTRODUCTION: The purpose of the study was to determine the surgical outcomes of intramedullary nailing in diaphyseal atypical femoral fractures (AFFs) and to evaluate the clinical outcomes of nail entry modification technique. MATERIALS AND METHODS: We retrospectively reviewed diaphyseal AFFs treated with IMN at nine institutions. In total, 82 patients were included. Surgical outcomes such as complication, union time, and femoral bowing were evaluated. We modified the nail entry of the straight nail from piriformis fossa to the tip of the greater trochanter in the bowed femur and compared the surgical outcomes between the original group and the modification group...
August 2, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28770273/atypical-femur-fractures-a-survey-of-current-practices-in-orthopedic-surgery
#17
P S Schneider, M Wall, J P Brown, A M Cheung, E J Harvey, S N Morin
The results of a self-administered online survey demonstrate that orthopedic surgeons' management practices for AFF are variable. These data will inform the development of clinical practice guidelines. INTRODUCTION: We aimed to determine current AFF treatment practices of orthopedic surgeons to inform clinical practice guideline development. METHODS: A self-administered online survey was developed and sequentially posted on the Orthopaedic Trauma Association (OTA) website from July to August 2015 and the Canadian Orthopaedic Association (COA) website from December 2015 to January 2016...
August 2, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28765053/metatarsal-periosteal-plantar-ganglion-cyst-associated-with-stress-fracture-a-case-report
#18
Kenji Serigano, Masayoshi Ikeda, Tadashi Nukaga, Masahiko Watanabe
We encountered a rare case of a periosteal ganglion cyst at the plantar aspect of the metatarsal that induced a stress fracture in a 77-year-old female. The clinical manifestation of the plantar ganglion cyst of the foot was not evident because of its location deep beneath the plantar fascia. A pressure cortical indentation was detected at the metatarsal neck on the initial radiographs. Magnetic resonance imaging showed a stress fracture of the metatarsal with a ganglion cyst. The stress fracture was thought to have resulted from several factors, including structural weakness due to bony absorption from the ganglion cyst, osteoporosis that induced a fragility fracture, and a load-induced fatigue fracture...
July 29, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28762443/atypical-femoral-fractures-and-biphosphonates
#19
Ali Jawad
[No Abstract Available].
August 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28760963/atypical-fracture-with-long-term-bisphosphonate-therapy-is-associated-with-altered-cortical-composition-and-reduced-fracture-resistance
#20
Ashley A Lloyd, Bernd Gludovatz, Christoph Riedel, Emma A Luengo, Rehan Saiyed, Eric Marty, Dean G Lorich, Joseph M Lane, Robert O Ritchie, Björn Busse, Eve Donnelly
Bisphosphonates are the most widely prescribed pharmacologic treatment for osteoporosis and reduce fracture risk in postmenopausal women by up to 50%. However, in the past decade these drugs have been associated with atypical femoral fractures (AFFs), rare fractures with a transverse, brittle morphology. The unusual fracture morphology suggests that bisphosphonate treatment may impair toughening mechanisms in cortical bone. The objective of this study was to compare the compositional and mechanical properties of bone biopsies from bisphosphonate-treated patients with AFFs to those from patients with typical osteoporotic fractures with and without bisphosphonate treatment...
August 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
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