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https://www.readbyqxmd.com/read/28340193/addressing-structural-barriers-to-hiv-care-among-triply-diagnosed-adults-project-bridge-oakland
#1
Christina Powers, Megan Comfort, Andrea M Lopez, Alex H Kral, Owen Murdoch, Jennifer Lorvick
People who are "triply diagnosed" with HIV, mental health issues, and substance-related disorders face tremendous barriers connecting to and remaining in HIV care. Authors of this article implemented Project Bridge Oakland (PBO), an intervention based on harm reduction and trauma-informed care, to help maintain continuity of care for triply diagnosed adults through cycles of criminal justice involvement. From August 2011 to December 2014, a clinical social worker and an HIV physician provided intensive case management for 19 clients living in Oakland, California...
March 14, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28339706/differential-proliferation-and-metabolic-activity-of-sertoli-cells-in-the-testes-of-broiler-and-layer-breeder-chickens
#2
Mélanie Faure, Edith Guibert, Sabine Crochet, Pascal Chartrin, Jean-Pierre Brillard, Anne Collin, Pascal Froment
Decades of genetic selection have generated 2 different, highly specialized types of chickens in which 1 type, known as the layer-type chicken, expresses high laying performance while the other type, known as the broiler-type chicken, is dedicated to the production of fast-growing birds. Selected lines for the latter type often express disorders in their reproductive performance including early sexual maturation and accelerated, non-reversible seasonal decline of their semen production and mating behavior. The aim of the present study was to characterize some metabolic markers of the Sertoli cell populations...
February 21, 2017: Poultry Science
https://www.readbyqxmd.com/read/28334810/bimodal-regulation-of-dishevelled-function-by-vangl2-during-morphogenesis
#3
Hwa-Seon Seo, Raymond Habas, Chenbei Chang, Jianbo Wang
Convergent extension (CE) is a fundamental morphogenetic mechanism that underlies numerous processes in vertebrate development, and its disruption can lead to human congenital disorders such as neural tube closure defects. The dynamic, oriented cell intercalation during CE is regulated by a group of core proteins identified originally in flies to coordinate epithelial planar cell polarity (PCP). The existing model explains how core PCP proteins, including Van Gogh (Vang) and Dishevelled (Dvl), segregate into distinct complexes on opposing cell cortex to coordinate polarity among static epithelial cells...
March 13, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28333997/learning-better-by-repetition-or-variation-is-transfer-at-odds-with-task-specific-training
#4
Emmanuel Bonney, Lemke Dorothee Jelsma, Gillian D Ferguson, Bouwien C M Smits-Engelsman
OBJECTIVE: Transfer of motor skills is the ultimate goal of motor training in rehabilitation practice. In children with Developmental Coordination Disorder (DCD), very little is known about how skills are transferred from training situations to real life contexts. In this study we examined the influence of two types of practice on transfer of motor skills acquired in a virtual reality (VR) environment. METHOD: One hundred and eleven children with DCD and their typically developing (TD) peers, aged 6-10 years (M = 8...
2017: PloS One
https://www.readbyqxmd.com/read/28333087/magnetically-bioprinted-human-myometrial-3d-cell-rings-as-a-model-for-uterine-contractility
#5
Glauco R Souza, Hubert Tseng, Jacob A Gage, Arunmani Mani, Pujan Desai, Fransisca Leonard, Angela Liao, Monica Longo, Jerrie S Refuerzo, Biana Godin
Deregulation in uterine contractility can cause common pathological disorders of the female reproductive system, including preterm labor, infertility, inappropriate implantation, and irregular menstrual cycle. A better understanding of human myometrium contractility is essential to designing and testing interventions for these important clinical problems. Robust studies on the physiology of human uterine contractions require in vitro models, utilizing a human source. Importantly, uterine contractility is a three-dimensionally (3D)-coordinated phenomenon and should be studied in a 3D environment...
March 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28327918/developmental-coordination-disorder-in-children-experimental-work-and-data-annotation
#6
Lukas Vareka, Petr Bruha, Roman Moucek, Pavel Mautner, Ladislav Cepicka, Irena Holeckova
Background: Developmental coordination disorder (DCD) is described as a motor skill disorder characterized by a marked impairment in the development of motor coordination abilities that significantly interferes with performance of daily activities and/or academic achievement. Since some electrophysiological studies suggest differences between children with/without motor development problems, we prepared an experimental protocol and performed electrophysiological experiments with the aim to make a step towards a possible diagnosis of this disorder using the event-related potentials (ERP) technique...
February 24, 2017: GigaScience
https://www.readbyqxmd.com/read/28326629/solvent-controlled-phase-transition-of-a-co-ii-organic-framework-from-achiral-to-chiral-and-two-to-three-dimen-sion
#7
Xing-Po Wang, Wen-Miao Chen, Xiao-Yu Li, Cyril Rajnák, Zhen-Yu Feng, Mohamedally Kurmoo, Roman Boča, Chunjiang Jia, Chen-Ho Tung, Di Sun
We report an unprecedented reversible dynamic transformation in a metal-organic framework involving bond formation that is accompanied by two important structural changes, achiral to chiral and two- to three-dimension. Using two bent organic lig-ands (diimpym = 4,6-di(1H-imidazol-1-yl)pyrimidine; H2npta = 5-nitroisophthalic acid) and CoII(NO3)2*6H2O the coordination pol-ymer Co(diimpym)(npta)*CH3OH, 1*CH3OH, was obtained sol-vothermally. Its structure consisting of knitted pairs of square layers (44-sql) of five-coordinated Co, disordered methanol and crystallizing in achiral Pbca space group at room temperature undergoes a single-crystal to single-crystal (SC-SC) transfor-mation to a 3D interpenetrated framework (pcu) of six-coordinated Co and ordered methanol in chiral P212121 space group below 220 K...
March 21, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28326047/preventing-internalizing-problems-in-young-children-a-randomized-controlled-trial-of-the-feelings-and-friends-year-3-program-with-a-motor-skills-component
#8
Ruhamah G Tennant, Katie K Martin, Rosanna Rooney, Sharinaz Hassan, Robert T Kane
Anxiety and depression are common mental health problems experienced by children in Australia. The impact of these internalizing disorders is pervasive, affecting many areas of life. By the time problems have been detected in children they can be severe in nature and harder to treat. Hence, early intervention is of utmost importance. Despite the existence of numerous prevention programs for children, there is limited empirical evidence for a program that has an impact on symptoms of both anxiety and depression...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28325112/potential-of-personal-health-record-portals-in-the-care-of-individuals-with-spinal-cord-injuries-and-disorders-provider-perspectives
#9
Jennifer N Hill, Bridget M Smith, Frances M Weaver, Kim M Nazi, Florian P Thomas, Barry Goldstein, Timothy P Hogan
CONTEXT/OBJECTIVE: Although personal health record (PHR) portals are designed for patients, healthcare providers are a key influence in how patients use their features and realize benefits from them. A few studies have examined provider attitudes toward PHR portals, but none have focused on those who care for individuals with spinal cord injuries and disorders (SCI/D). We characterize SCI/D provider perspectives of PHR portals, including perceived advantages and disadvantages of PHR portal use in SCI/D care...
March 21, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28325099/client-centred-practice-from-the-perspective-of-danish-patients-with-hand-related-disorders
#10
Alice Ørts Hansen, Hanne Kaae Kristensen, Ragnhild Cederlund, Henrik Hein Lauridsen, Hans Tromborg
PURPOSE: The objectives of this study were to investigate perceptions of client-centred practice among Danish patients with hand-related disorders engaged in rehabilitation at outpatient clinics, and to decide on domains to serve as a conceptual foundation for item generation in the development of a new, standardized questionnaire to evaluate the experience of client-centredness among patients with hand-related disorders. METHOD: Focus group interviews were held with 25 patients with hand-related disorders from six outpatient hand clinics in Denmark...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28323548/referral-to-treatment-for-hospitalized-medical-patients-with-an-alcohol-use-disorder-a-proof-of-concept-brief-intervention-study
#11
Lisa Berger, Jennifer Hernandez-Meier, John Hyatt, Michael Brondino
Substance misuse intervention in healthcare settings is becoming a US national priority, especially in the dissemination and implementation of Screening, Brief Intervention, and Referral to Treatment (SBIRT). Yet, the referral to treatment component of SBIRT is understudied. This proof-of-concept investigation tested an enhanced coordinated hospital-community two session brief intervention designed to facilitate the referral to treatment of hospitalized medical patients with an alcohol use disorder. Participants (N = 9) attended the second session of the brief intervention held in the community in most cases (56%), while one out of three (33%) received some level of post-brief intervention alcohol and/or other drug treatment...
March 21, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28322886/high-gamma-oscillations-in-the-motor-cortex-during-visuo-motor-coordination-a-tacs-interferential-study
#12
E Santarnecchi, A Biasella, E Tatti, A Rossi, D Prattichizzo, S Rossi
BACKGROUND: While the role of beta (∼20Hz), theta (∼5Hz) and alpha (∼10Hz) oscillations in the motor areas have been repeatedly associated with defined properties of motor performance, the investigation of gamma (∼40-90Hz) oscillatory activity is a more recent and still not fully understood component of motor control physiology, despite its potential clinical relevance for motor disorders. OBJECTIVE/HYPOTHESIS: We have implemented an online neuromodulation paradigm based on transcranial alternating current stimulation (tACS) of the dominant motor cortex during a visuo-motor coordination task...
March 18, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28321184/the-role-of-early-growth-response-1-egr1-in-brain-plasticity-and-neuropsychiatric-disorders
#13
REVIEW
Florian Duclot, Mohamed Kabbaj
It is now clearly established that complex interactions between genes and environment are involved in multiple aspects of neuropsychiatric disorders, from determining an individual's vulnerability to onset, to influencing its response to therapeutic intervention. In this perspective, it appears crucial to better understand how the organism reacts to environmental stimuli and provide a coordinated and adapted response. In the central nervous system, neuronal plasticity and neurotransmission are among the major processes integrating such complex interactions between genes and environmental stimuli...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28320271/interplay-between-brain-bdnf-and-glutamatergic-systems-a-brief-state-of-the-evidence-and-association-with-the-pathogenesis-of-depression
#14
REVIEW
N V Gulyaeva
The excitatory neurotransmitter glutamate system and the brain-derived neurotrophic factor (BDNF) system are principally involved in phenomena of cellular and synaptic plasticity. These systems are interacting, and disclosing mechanisms of such interactions is critically important for understanding the machinery of neuroplasticity and its modulation in normal and pathological situations. The short state of evidence in this review addresses experimentally confirmed connections of these mechanisms and their potential relation to the pathogenesis of depression...
March 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28320224/identification-of-common-neural-circuit-disruptions-in-cognitive-control-across-psychiatric-disorders
#15
Lisa M McTeague, Julia Huemer, David M Carreon, Ying Jiang, Simon B Eickhoff, Amit Etkin
OBJECTIVE: Cognitive deficits are a common feature of psychiatric disorders. The authors investigated the nature of disruptions in neural circuitry underlying cognitive control capacities across psychiatric disorders through a transdiagnostic neuroimaging meta-analysis. METHOD: A PubMed search was conducted for whole-brain functional neuroimaging articles published through June 2015 that compared activation in patients with axis I disorders and matched healthy control participants during cognitive control tasks...
March 21, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28318734/effects-of-acetone-cyanohydrin-a-derivative-of-cassava-on-motor-activity-and-kidney-and-liver-function-in-wistar-rats
#16
E Rivadeneyra-Domínguez, C J Rosas-Jarquín, A Vázquez-Luna, R Díaz-Sobac, J F Rodríguez-Landa
INTRODUCTION: Acetone cyanohydrin (ACH) is a toxic substance present in cassava roots (Manihot esculenta Crantz) which results from enzymatic hydrolysis of linamarin. Long-term consumption is associated with 2 neurological disorders: konzo and tropical ataxic neuropathy. Previous studies have evaluated behavioural alterations linked to ACH consumption, but the toxic effects of this substance on physiological processes remain unknown. METHOD: 32 male Wistar rats were assigned to 4 experimental groups (n=8 per group): a vehicle group (0...
March 16, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28316824/structure-of-the-mercury-ii-mixed-halide-br-cl-complex-of-2-2-5-tert-butyl-1-3-phenyl-ene-bis-1-pentyl-1h-benzo-d-imidazole
#17
Varsha Rani, Harkesh B Singh, Ray J Butcher
The mercury(II) complex of 2,2'-(5-tert-butyl-1,3-phenyl-ene)bis-(1-pentyl-1H-benz-imidazole), namely catena-poly[[dihalogenido-mercury(II)]-μ-2,2'-(5-tert-butyl-1,3-phenyl-ene)bis-(1-pentyl-1H-benzimidazole)-κ(2)N(3):N(3')], [HgBr1.52Cl0.48(C34H42N4)], 2, has a polymeric structure bridging via the N atoms from the benzimidazole moieties of the ligand. The compound crystallizes in the ortho-rhom-bic space group Pca21 and is a racemic twin [BASF = 0.402 (9)]. The geometry around the Hg(II) atom is distorted tetra-hedral, with the Hg(II) atom coordinated to two N atoms, one Br atom, and a fourth coordination site is occupied by a mixed halide (Br/Cl)...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28316819/crystal-structure-of-bis-oxalato-%C3%AE%C2%BA-2-o-1-o-2-1-4-8-11-tetra-aza-cyclo-tetra-decane-%C3%AE%C2%BA-4-n-chromium-iii-dichromate-octa-hydrate-from-synchrotron-x-ray-data
#18
Dohyun Moon, Jong-Ha Choi
The asymmetric unit of the title compound, [Cr(C2O4)(C10H24N4)]2[Cr2O7]·8H2O (C10H24N4 = 1,4,8,11-tetra-aza-cyclo-tetra-decane, cyclam; C2O4 = oxalate, ox) contains one [Cr(ox)(cyclam)](+) cation, one half of a dichromate anion that lies about an inversion centre so that the bridging O atom is equally disordered over two positions, and four water mol-ecules. The terminal O atoms of the dichromate anion are also disordered over two positions with a refined occupancy ratio 0.586 (6):0.414 (6). The Cr(III) ion is coordinated by the four N atoms of the cyclam ligand and one bidentate oxalato ligand in a cis arrangement, resulting in a distorted octa-hedral geometry...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28316813/crystal-structure-of-poly-aqua-%C3%AE-2-3-di-hydro-thieno-3-4-b-1-4-dioxine-5-7-di-carboxyl-ato-%C3%AE%C2%BA-2-o-5-o-7-%C3%AE-di-pyridin-4-yl-sulfane-%C3%AE%C2%BA-2-n-n-zinc-0-26-hydrate
#19
Wen-Liang Wu, Bing Hu
The crystal structure of the title polymer, {[Zn(C8H4O6S)(C10H8N2S)(H2O)]·0.26H2O} n , is characterized by a layered arrangement parallel to the ab plane. The zinc cation is five-coordinated in a slightly distorted trigonal-bipyramidal coordination environment defined by two pyridine ligands, two carboxyl-ate groups of two thio-phene di-carboxyl-ate ligands, and by one water mol-ecule. The ethyl-ene bridge in the dioxine ligand is disordered over two sets of sites [occupancy ratio 0.624 (9):0.376 (9)]...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28316800/bis-%C3%AE-benzoato-%C3%AE%C2%BA-2-o-o-bis-benzoato-%C3%AE%C2%BAo-octabutyldi-%C3%AE-3-oxido-tetra-tin-iv
#20
Hans Reuter, Coco K Y A Okio
The asymmetric unit of the title compound, [{Sn(C4H9)2(C6H5COO)}2O]2, consists of two half molecules, completed by application of inversion symmetry. Both mol-ecules adopt a ladder structure typical for this class of dimeric tetra-organodistannoxane di-carboxyl-ates characterized by a centrosymmetric four-membered (Sn-O)2 ring of rhomboidal shape that is extended on both sides by folded six-membered Sn-O-C rings. To a first approximation, both kinds of Sn atoms (Sn i and Sn o ) are trigonal-bipyramidally coordinated...
March 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
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