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breast implant radiation therapy

Summer E Hanson, Benjamin D Smith, Jun Liu, Geoffrey L Robb, Steven J Kronowitz, Patrick B Garvey
: The most commonly chosen flaps for delayed breast reconstruction after postmastectomy radiation therapy (PMRT) are abdominal-based free flaps (ABFFs) and pedicled latissimus dorsi (LD) musculocutaneous flaps. The short-and long-term advantages and disadvantages of delayed ABFFs versus LD flaps after PMRT remain unclear. We hypothesized that after PMRT, ABFFs would result in fewer postoperative complications and a lower incidence of revision surgery than LD flaps. METHODS: We retrospectively reviewed a prospectively maintained database of consecutive patients who underwent unilateral, delayed breast reconstruction after PMRT using ABFFs or pedicled LD flaps with implants at the MD Anderson Cancer Center between January 1, 2001, and December 31, 2011...
September 2016: Plastic and Reconstructive Surgery. Global Open
S Yuce Sari, A Kotek, M Gultekin, B Akkus Yildirim, C Onal, G Ozyigit, M Gurkaynak, F Yildiz
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Joseph A Ricci, Matthew D Treiser, Ran Tao, Wei Jiang, Gretchen Guldbrandsen, Eric Halvorson, Charles A Hergrueter, Yoon S Chun
BACKGROUND: Implant-based breast reconstruction with an acellular dermal matrix is one of the most common procedures performed by plastic surgeons. Although numerous matrices are available, there is little literature comparing them. This study compares the rates of complications between two commonly used products: AlloDerm (human cadaveric) and SurgiMend (fetal bovine) acellular dermal matrices. METHODS: A retrospective review of a single center's 6-year experience was performed for consecutive, immediate breast reconstructions with acellular dermal matrix from 2009 to 2014...
October 2016: Plastic and Reconstructive Surgery
Katherine B Santosa, Xiaoxue Chen, Ji Qi, Tiffany N S Ballard, Hyungjin M Kim, Jennifer B Hamill, Jessica M Bensenhaver, Andrea L Pusic, Edwin G Wilkins
BACKGROUND: The ideal timing of postmastectomy radiation therapy (PMRT) in the setting of two-stage implant-based breast reconstruction remains unclear. In this cohort study, the authors sought to determine whether complication rates differed between patients who received PMRT following tissue expander placement (TE-XRT) and those who received PMRT after exchange for permanent implants (Implant-XRT) utilizing using prospective, multicenter data. METHODS: Eligible patients in the Mastectomy Reconstruction Outcomes Consortium study from 11 institutions across North America were included in the analysis...
October 2016: Plastic and Reconstructive Surgery
Tarcisio Passos Ribeiro de Campos, Luciana Batista Nogueira, Bruno Trindade, Ethel Mizrahy Cuperschmid
AIM: To provide a comparative dosimetric analysis of permanent implants of Ho(166)-seeds and temporary HDR Ir(192)-brachytherapy through computational simulation. BACKGROUND: Brachytherapy with Ir(192)-HDR or LDR based on temporary wires or permanent radioactive seed implants can be used as dose reinforcement for breast radiation therapy. Permanent breast implants have not been a practical clinical routine; although, I(125) and Pd(103)-seeds have already been reported...
May 2016: Reports of Practical Oncology and Radiotherapy
Donato Casella, Claudio Calabrese, Lorenzo Orzalesi, Ilaria Gaggelli, Lorenzo Cecconi, Caterina Santi, Roberto Murgo, Stefano Rinaldi, Lea Regolo, Claudio Amanti, Manuela Roncella, Margherita Serra, Graziano Meneghini, Massimiliano Bortolini, Vittorio Altomare, Carlo Cabula, Francesca Catalano, Alfredo Cirilli, Francesco Caruso, Maria Grazia Lazzaretti, Icro Meattini, Lorenzo Livi, Luigi Cataliotti, Marco Bernini
BACKGROUND: Reconstruction options following nipple-sparing mastectomy (NSM) are diverse and not yet investigated with level IA evidence. The analysis of surgical and oncological outcomes of NSM from the Italian National Registry shows its safety and wide acceptance both for prophylactic and therapeutic cases. A further in-depth analysis of the reconstructive approaches with their trend over time and their failures is the aim of this study. METHODS: Data extraction from the National Database was performed restricting cases to the 2009-2014 period...
September 6, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Thomas Lam, James Salinas, Frank Hsieh, John Boyages
BACKGROUND: There is a paucity of data regarding outcomes for patients undergoing breast augmentation with implants after breast conservation surgery (BCS) and radiotherapy. This retrospective study examined outcomes for patients with breast implant-only augmentation after BCS and radiotherapy. METHODS: Between June 1998 and December 2010, 671 women underwent prosthetic breast reconstruction. Nineteen patients (2.8%) underwent an augmentation after BCS and radiotherapy...
July 2016: Plastic and Reconstructive Surgery. Global Open
Hoon Kim, Chi Sun Yoon, Hoon Bum Lee, Byung Kyun Ko, Gyu Yeol Kim, Kyu Nam Kim
INTRODUCTION: Potential challenges associated with immediate small breast reconstruction include an inadequate size of the donor site, a thinner skin envelope and limited selection of implants. We present immediate postmastectomy reconstruction of small breasts with a laparoscopically harvested pedicled omental flap (LHPOF) in five Korean women. METHODS: From December 2014 to July 2015, we performed immediate postmastectomy reconstruction with an LHPOF in five breast cancer patients...
August 3, 2016: ANZ Journal of Surgery
Mihye Choi, Jordan D Frey, Michael Alperovich, Jamie P Levine, Nolan S Karp
BACKGROUND: Nipple-sparing mastectomy with immediate, permanent implant reconstruction offers patients a prosthetic "breast in a day" compared to tissue expander techniques requiring multiple procedures. METHODS: Patients undergoing nipple-sparing mastectomy with immediate, permanent implant reconstruction were reviewed with patient demographics and outcomes analyzed. RESULTS: Of 842 nipple-sparing mastectomies from 2006 to June of 2015, 160 (19...
August 2016: Plastic and Reconstructive Surgery
Diana L Caragacianu, Erica L Mayer, Yoon S Chun, Stephanie Caterson, Jennifer R Bellon, Julia S Wong, Susan Troyan, Esther Rhei, Laura S Dominici, Katherine E Economy, Nadine M Tung, Lidia Schapira, Ann Partridge, Katherina Zabicki Calvillo
BACKGROUND: Surgical management of breast cancer in pregnancy (BCP) requires balancing benefits of therapy with potential risks to the developing fetus. Minimal data describe outcomes after mastectomy with immediate breast reconstruction (IR) in pregnant patients. METHODS: Retrospective review was performed of patients who underwent IR after mastectomy within a BCP cohort. Parameters included intra- and post-operative complications, short-term maternal/fetal outcomes, surgery duration, and delayed reconstruction in non-IR cohort...
August 2016: Journal of Surgical Oncology
Karen E Mooney, Michael B Altman, Sharbacha Edward, Jose Garcia-Ramirez, Maria A Thomas, Imran Zoberi, Todd DeWees, Daniel Mullen, Jacqueline E Zoberi
PURPOSE: Current guidelines for high-dose-rate accelerated partial breast irradiation using single-entry implants are based on the National Surgical Adjuvant Breast and Bowel Project B-39/Radiation Therapy Oncology Group 0413 protocol, which assumed a balloon implant geometry. We have developed robust plan evaluation criteria specifically for the strut-adjusted volume implant (SAVI). METHODS AND MATERIALS: Plan evaluation criteria were established using a "training data set" of 62 SAVI treatment plans and included the percentage volume of target receiving 90%, 95%, and 100% of the prescription dose (V90, V95, and V100), the absolute volume of target receiving 150% and 200% of prescription (V150 and V200), and the maximum doses to skin (Dskin max) and ribs (Drib max)...
September 2016: Brachytherapy
Murat Fani Bozkurt, Bilge Volkan Salanci, Ömer Uğur
Intra-arterial radionuclide therapies serve essentially as internal radiation treatment options for both primary and metastatic liver tumors, which imply delivering implantable radioactive microspheres into branches of hepatic arteries that feed liver tumors to provide a high dose of targeted radiation to tumor tissue, while sparing the healthy liver tissue from hazardous effects of radiation. The principle of this therapeutic option depends on the unique preferential arterial supply of malignant liver tumors in contrast with mostly portal venous supply of normal hepatocytes as well as excess amount of arterial neovascularization in the tumor bed...
July 2016: Seminars in Nuclear Medicine
N Paillocher, A S Florczak, M Richard, J M Classe, A S Oger, P Raro, R Wernert, G Lorimier
PURPOSE: The aim of the study was to evaluate morbidity and patient satisfaction following surgically treated skin-sparing mastectomy (SSM) with immediate breast reconstruction (IBR) following mastectomy with neoadjuvant chemotherapy (NACT), and preoperative radiotherapy (RT), for operable invasive breast cancer. PATIENTS AND METHODS: This retrospective single-institution study included 111 patients who underwent a mastectomy with IBR after RT and/or NACT for invasive breast carcinoma at the Institut de Cancérologie de l'Ouest Paul Papin from January 1997 to January 2012...
July 2016: European Journal of Surgical Oncology
M E A Klinger, L Maione, A V E Lisa, V Vinci, A Torre, F Klinger
No abstract text is available yet for this article.
April 2016: European Review for Medical and Pharmacological Sciences
Anita T Mohan, Michel Saint-Cyr
The role and choice of preoperative imaging for planning in breast reconstruction is still a disputed topic in the reconstructive community, with varying opinion on the necessity, the ideal imaging modality, costs and impact on patient outcomes. Since the advent of perforator flaps their use in microsurgical breast reconstruction has grown. Perforator based flaps afford lower donor morbidity by sparing the underlying muscle provide durable results, superior cosmesis to create a natural looking new breast, and are preferred in the context of radiation therapy...
April 2016: Gland Surgery
Ellen S Satteson, Michael F Reynolds, Austin M Bond, Ivo A Pestana
Nipple-areola reconstruction represents the completion of the breast restorative process and is associated with significant positive psychological implications. While factors such as medical comorbidities, smoking status, and radiation therapy have been shown to be associated with an increase in complications following breast reconstruction, their impact on nipple reconstruction remains largely unaddressed in the literature. An IRB-approved, retrospective review of 472 patients who underwent nipple reconstruction at Wake Forest University over a 15-year period was completed...
July 2016: Breast Journal
Jason Roostaeian, Alfred P Yoon, Shannon Ordon, Chris Gold, Christopher Crisera, Jaco Festekjian, Andrew Da Lio, Joan E Lipa
BACKGROUND: Implant-based breast reconstructions can result in unsatisfactory results requiring surgical revision or salvage reconstructive surgery with autologous tissue. This study compares the outcomes and complications of salvage (tertiary) flap reconstruction after failed prosthesis placement to those of primary/secondary flap reconstruction. METHODS: All patients undergoing free flap breast reconstruction after failed prosthesis between July 1, 2005, and June 30, 2014, were identified...
April 2016: Plastic and Reconstructive Surgery
Martine A van Huizum, J Joris Hage, Emiel J Rutgers, Marije J Hoornweg
BACKGROUND: Local relapse after breast-conserving therapy including whole breast irradiation is typically treated by salvage mastectomy. Immediate reconstruction by pedicled transfer of a latissimus dorsi flap in combination with implantation of a definitive prosthesis or temporary tissue expander following skin sparing salvage mastectomy has been shown to be feasible. However, it has never been shown to be justifiable. AIM: The aim of the study was to compare the outcome of this procedure to the widely accepted secondary breast reconstruction by combined latissimus dorsi flap and implant after mastectomy and adjuvant radiotherapy...
August 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
T A Fantaneanu, G Tillman, E Garcia, T Grady, B A Dworetzky
BACKGROUND: Epilepsy and breast cancer are both prevalent conditions. A subset of women with medically refractory epilepsy and vagus nerve stimulators (VNS) may later develop breast cancer and may require adjuvant radiation as part of their treatment regimen. However, to date, little data are available on the effects of radiation on VNS function. CASE PRESENTATION: We present a young woman with tuberous sclerosis, developmental delay, and medically refractory epilepsy who developed left-sided breast cancer...
March 10, 2016: Acta Neurologica Scandinavica
Lauren Hewell Fischer, Dung Nguyen
INTRODUCTION: Tissue expander-based reconstruction in the irradiated breast has been associated with significant complications, including infection, skin breakdown and implant extrusion, and poor aesthetic outcome. These complications may be attributed to inadequate lower pole expansion causing increased pressure on the suture line. Achieving and maintaining adequate lower pole expansion in the reconstructed breast requiring adjuvant radiation therapy may reduce the pressure/strain on the suture line and preserve the natural appearance of the breast...
May 2016: Annals of Plastic Surgery
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