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c reactive protein in cardiac patients

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https://www.readbyqxmd.com/read/27913750/congenital-heart-block-and-immune-mediated-sensorineural-hearing-loss-possible-cross-reactivity-of-immune-response
#1
C Bason, I Pagnini, A Brucato, S Maestroni, A Puccetti, C Lunardi, R Cimaz
Immune-mediated sensorineural hearing loss may complicate systemic autoimmune diseases. We have previously reported the presence of antibodies directed against inner ear antigens in patients with Cogan syndrome, a disease characterized by sudden hearing loss and interstitial keratitis. Such autoantibodies cross-react with an epitope of SSA/Ro60 protein. Anti-Ro/SSA antibodies in pregnant women cross the placenta and reach the fetal tissues inducing an immune-mediated damage of the cardiac conduction system...
December 2, 2016: Lupus
https://www.readbyqxmd.com/read/27904574/comparison-of-early-period-results-of-blood-use-in-open-heart-surgery
#2
Serhat Huseyin, Volkan Yuksel, Orkut Guclu, Fatma Nesrin Turan, Suat Canbaz, Turan Ege, Hasan Sunar
BACKGROUND: Various adverse effects of homologous blood transfusion detected particularly in open heart surgery, in which it is frequently used, lead researchers to study on autologous blood use and to evaluate the patient's blood better. Due to the complications of homologous blood transfusion, development of techniques that utilize less transfusion has become inevitable. We aimed to evaluate the effects of acute normovolemic hemodilution (ANH) in patients undergoing open heart surgery...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27902530/cardiac-troponin-release-is-associated-with-biomarkers-of-inflammation-and-ventricular-dilatation-during-critical-illness
#3
Marlies Ostermann, Salma Ayis, Emma Tuddenham, Jessica Lo, Katie Lei, John Smith, Barnaby Sanderson, Carl Moran, Paul Collinson, Janet Peacock, Andrew Rhodes, David Treacher
INTRODUCTION: Troponin release is common during critical illness. We hypothesized that there was an association between cardiac troponin T (cTnT) and biomarkers of systemic inflammation and ventricular dilatation. METHODS: In an observational prospective cohort study, we enrolled consecutive adult patients admitted for non-cardiac reasons to the Intensive Care Unit (ICU) in 2 tertiary care centers. We measured cTnT, C-reactive protein (CRP), Interleukin-6 (IL-6), procalcitonin (PCT) and N-terminal pro brain natriuretic peptide (NT-proBNP) daily in the first week, and on alternate days in the second week...
November 29, 2016: Shock
https://www.readbyqxmd.com/read/27894261/multimarker-approach-for-the-prediction-of-microvascular-obstruction-after-acute-st-segment-elevation-myocardial-infarction-a-prospective-observational-study
#4
Hans-Josef Feistritzer, Sebastian Johannes Reinstadler, Gert Klug, Martin Reindl, Sebastian Wöhrer, Christoph Brenner, Agnes Mayr, Johannes Mair, Bernhard Metzler
BACKGROUND: Presence of microvascular obstruction (MVO) derived from cardiac magnetic resonance (CMR) imaging is among the strongest outcome predictors after ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the comparative predictive values of different biomarkers for the occurrence of MVO in a large cohort of reperfused STEMI patients. METHODS: This study included 128 STEMI patients. CMR imaging was performed within the first week after infarction to assess infarct characteristics, including MVO...
November 28, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27871168/long-term-prognosis-of-end-stage-renal-disease-patients-with-normal-myocardial-perfusion-as-determined-by-single-photon-emission-computed-tomography
#5
Gun Ha Park, Jae Won Song, Chang Min Lee, Young Rim Song, Sung Gyun Kim, Hyung Jik Kim, Jwa Kyung Kim
Background/Aims: Normal myocardial perfusion is closely associated with very low rates of cardiac events and better long-term outcomes; however, little is known about its prognostic value in patients with end-stage renal disease (ESRD). Methods: A total of 286 incident patients underwent baseline cardiac evaluations using echocardiography and stress-rest single-photon emission computed tomography. Perfusion scans for 177 patients (61.9%) who had a summed stress score (SSS) < 4 were normal...
November 22, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27870908/n-terminal-pro-b-type-natriuretic-peptide-as-a-biomarker-for-loss-of-muscle-mass-in-prevalent-hemodialysis-patients
#6
Misa Ikeda, Hirokazu Honda, Keiko Takahashi, Kanji Shishido, Takanori Shibata
Protein-energy wasting (PEW) is common in hemodialysis (HD) patients. A recent study demonstrated that a high level of N-terminal pro-B-type natriuretic peptide (NT-proBNP) may be associated with PEW in those patients. This prospective study aimed to assess the association of NT-proBNP with body composition and muscle loss. A cohort of prevalent HD patients (n = 238) was examined. Blood samples were obtained at baseline to measure high-sensitive C-reactive protein (hsCRP), interleukin-6 (IL-6), adiponectin and NT-proBNP...
2016: PloS One
https://www.readbyqxmd.com/read/27867158/preprocedural-high-sensitivity-c-reactive-protein-predicts-long-term-outcome-of-percutaneous-coronary-intervention
#7
Hideki Wada, Tomotaka Dohi, Katsumi Miyauchi, Jun Shitara, Hirohisa Endo, Shinichiro Doi, Ryo Naito, Hirokazu Konishi, Shuta Tsuboi, Manabu Ogita, Takatoshi Kasai, Ahmed Hassan, Shinya Okazaki, Kikuo Isoda, Kazunori Shimada, Satoru Suwa, Hiroyuki Daida
BACKGROUND: High-sensitivity C-reactive protein (hs-CRP) has been used to predict the risk of adverse cardiac events in patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI). Less is known, however, about the association between hs-CRP and long-term outcome after PCI in the Japanese population.Methods and Results:We studied 3,039 all-comer patients with CAD who underwent their first PCI and had data available for preprocedural hs-CRP at Juntendo University between 2000 and 2011...
November 19, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27864387/increased-trimethylamine-n-oxide-portends-high-mortality-risk-independent-of-glycemic-control-in-patients-with-type-2-diabetes-mellitus
#8
W H Wilson Tang, Zeneng Wang, Xinmin S Li, Yiying Fan, Daniel S Li, Yuping Wu, Stanley L Hazen
BACKGROUND: Recent studies show a mechanistic link between intestinal microbial metabolism of dietary phosphatidylcholine and coronary artery disease pathogenesis. Concentrations of a proatherogenic gut microbe-generated metabolite, trimethylamine N-oxide (TMAO), predict increased incident cardiovascular disease risks in multiple cohorts. TMAO concentrations are increased in patients with type 2 diabetes mellitus (T2DM), but their prognostic value and relation to glycemic control are unclear...
November 18, 2016: Clinical Chemistry
https://www.readbyqxmd.com/read/27863892/pericarditis-mimicking-brugada-syndrome-a-case-report
#9
Manuel Monti, Giulia Olivi, Francesca Francavilla, Francesco Borgognoni
INTRODUCTION: Brugada syndrome (BrS) is a genetic heart disorder due to alteration of the ion channels function that causes an impaired in the cardiac conduction system. It is characterized by an abnormal electrocardiogram pattern and may be complicated by malignant ventricular arrhythmias. Pericarditis is an inflammation of the pericardium and 90% of isolated cases of acute pericarditis are idiopathic or viral. Acute pericarditis may appears with chest pain, fever, pericardial friction rub, and cardiac tamponade...
November 9, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27858345/myocardial-123-i-mibg-scintigraphy-in-relation-to-markers-of-inflammation-and-long-term-clinical-outcome-in-patients-with-stable-chronic-heart-failure
#10
Derk O Verschure, René Lutter, Berthe L F van Eck-Smit, G Aernout Somsen, Hein J Verberne
AIM: Chronic heart failure (CHF) results in both increased cardiac sympathetic activity and myocardial inflammation. The aim of this study was to identify the relationship between severity of heart failure (i.e., NT-proBNP and LVEF), cardiac sympathetic activity ((123)I-mIBG scintigraphy), and measures of inflammation in subjects with stable, optimally treated CHF. In addition, the predictive value for cardiac events (i.e., ventricular arrhythmia, progression of CHF and cardiac death) of (123)I-mIBG parameters and these inflammatory markers was evaluated...
November 17, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27852696/insights-into-cardiac-involvement-in-ankylosing-spondylitis-from-cardiovascular-magnetic-resonance
#11
P Stefan Biesbroek, Sjoerd C Heslinga, Thelma C Konings, Irene E van der Horst-Bruinsma, Mark B M Hofman, Peter M van de Ven, Otto Kamp, Vokko P van Halm, Mike J L Peters, Yvo M Smulders, Albert C van Rossum, Mike T Nurmohamed, Robin Nijveldt
OBJECTIVE: To evaluate cardiac involvement in patients with ankylosing spondylitis using cardiac magnetic resonance (CMR). METHODS: Patients with ankylosing spondylitis without cardiovascular symptoms or known cardiovascular disease were screened by transthoracic echocardiography (TTE) for participation in this exploratory CMR study. We prospectively enrolled 15 ankylosing spondylitis patients with an abnormal TTE for further tissue characterisation using late gadolinium enhancement (LGE) and T1 mapping...
November 16, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27826974/can-n-terminal-pro-b-type-natriuretic-peptide-neutrophil-to-lymphocyte-ratio-c-reactive-protein-help-to-predict-short-and-long-term-mortality
#12
I Ozmen, Z Karakurt, C Salturk, F Kargin, H B Takir, E Aksoy, R Sari, E Celik, E A Tuncay, E Yildirim, O Y Mocin, N Adiguzel, S Oztas, S Gungor, G Gungor
BACKGROUND: There is limited data about ICU, short and long-term mortality prediction of severe CAP with neutrophil-to-lymphocyte ratio (NLR): N-terminal proB- type natriuretic peptide (NT-proBNP): C-reactive protein (CRP). AIM: Besides the known severity indexes of ICU, can NLR, NT-proBNP, CRP predict ICU, short and long term mortality? METHODS: A retrospective cohort study was carried out in a level III ICU of a tertiary training hospital for chest diseases and thoracic surgery...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826709/risk-factors-for-cardiac-arrest-or-mechanical-circulatory-support-in-children-with-fulminant-myocarditis
#13
Joseph R Casadonte, Mjaye L Mazwi, Katheryn E Gambetta, Hannah L Palac, Mary E McBride, Osama M Eltayeb, Michael C Monge, Carl L Backer, John M Costello
In children with fulminant myocarditis (FM), we sought to describe presenting characteristics and clinical outcomes, and identify risk factors for cardiac arrest and mechanical circulatory support (MCS). A retrospective review of patients with FM admitted at our institution between January 1, 2004, and June 31, 2015, was performed. We compared characteristics and outcomes of FM patients who received cardiopulmonary resuscitation (CPR) and/or were placed on MCS (CPR/MCS group) to those who did not develop these outcomes (Control group)...
November 8, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27813364/magnetic-resonance-detected-myocardial-inflammation-and-fibrosis-in-rheumatoid-arthritis-associations-of-disease-characteristics-and-n-terminal-pro-brain-natriuretic-peptide-levels
#14
Hitomi Kobayshi, Yasuyuki Kobayashi, Isamu Yokoe, Yosikatsu Akashi, Masami Takei, Jon T Giles
Objective Myocardial dysfunction and heart failure (HF) are increased in rheumatoid arthritis (RA), yet there are few studies of the RA myocardium. Methods RA patients with no known heart disease or risk factors underwent gadolinium-enhanced cardiac magnetic resonance (cMR) imaging. Images were assessed for left-ventricular (LV) structure and functional parameters, and for myocardial late gadolinium enhancement (LGE: an indicator of myocardial fibrosis) and T2-weighted imaging (T2WI: an indicator of active inflammation)...
November 3, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27799236/effects-of-statin-on-arrhythmia-and-heart-rate-variability-in-healthy-persons-with-48-hour-sleep-deprivation
#15
Wei Ren Chen, Hong Bin Liu, Yuan Sha, Yang Shi, Hao Wang, Da Wei Yin, Yun Dai Chen, Xiang Min Shi
BACKGROUND: It has been reported that sleep deprivation is associated with cardiac autonomic disorder, inflammation, and oxidative stress. Statins have significant cardiovascular protective effects in patients with cardiovascular disease. This study aimed to investigate the protective effect of statins on arrhythmia and heart rate variability in young healthy persons after 48-hour sleep deprivation. METHODS AND RESULTS: This study enrolled 72 young healthy participants aged 26...
October 31, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27798199/predictors-of-atherosclerotic-events-in-patients-on-haemodialysis-post-hoc-analyses-from-the-aurora-study
#16
Marit D Solbu, Geir Mjøen, Patrick B Mark, Hallvard Holdaas, Bengt Fellström, Roland E Schmieder, Faiez Zannad, William G Herrington, Alan G Jardine
BACKGROUND: Patients on haemodialysis (HD) are at high risk for cardiovascular events, but heart failure and sudden death are more common than atherosclerotic events. The A Study to Evaluate the Use of Rosuvastatinin in Subjects on Regular Hemodialysis: An Assessment of Survival and Cardiovascular Events (AURORA) trial was designed to assess the effect of rosuvastatin on myocardial infarction and death from any cardiac cause in 2773 HD patients. We studied predictors of the atherosclerotic cardiovascular events in AURORA...
October 17, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27795837/effects-of-low-dose-selenium-on-the-inflammatory-response-in-coronary-artery-bypass-graft-surgery-a-clinical-trial
#17
Abbas Sedighinejad, Vali Imantalab, Ali Mirmansouri, Ali Mohammadzadeh Jouryabi, Gholamreza Kanani, Nassir Nassiri Sheikhani, Mohammad Haghighi, Zahra Atrkarroushan, Gelareh Biazar
BACKGROUND: Coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB) triggers an inflammatory reaction, leading to the development of myocardial damage and dysfunction. It is suggested that selenium (Se), an essential trace element, has a protective role against oxidative stress. Decreased intraoperative Se levels might be an independent predictive factor for postoperative multiorgan failure. In spite of its proposed advantages, however, the optimal timing and dosage are not well known...
August 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27779166/association-of-plasma-pentraxin-3-levels-on-admission-with-in-hospital-mortality-in-patients-with-acute-type-a-aortic-dissection
#18
Qin Zhou, Xiang-Ping Chai, Zhen-Fei Fang, Xin-Qun Hu, Liang Tang
BACKGROUND: Acute aortic dissection is a life-threatening cardiovascular emergency. Pentraxin-3 (PTX3) is proposed as a prognostic marker and found to be related to worse clinical outcomes in various cardiovascular diseases. This study sought to investigate the association of circulating PTX3 levels with in-hospital mortality in patients with acute Type A aortic dissection (TAAD). METHODS: A total of 98 patients with TAAD between January 2012 and December 2015 were enrolled in this study...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27779165/independent-prognostic-value-of-high-sensitivity-c-reactive-protein-in-patients-with-coronary-artery-ectasia
#19
Yintang Wang, Yang Wang, Shijie You, Hongjian Wang, Dong Yin, Kefei Dou, Weihua Song
BACKGROUND: Despite its severity, coronary artery ectasia (CAE) is still poorly understood. High-sensitivity C-reactive protein (hs-CRP) has been recognized as a prognostic factor in some cardiovascular diseases but not assessed in CAE. The aim of this observational study was to investigate the prognostic value of hs-CRP in CAE. METHODS: Our analysis evaluated the effect of the baseline hs-CRP on cardiovascular events (CVs) (cardiac death and nonfetal myocardial infarction) in consecutively enrolled stable CAE patients...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27774271/circulating-biomarker-responses-to-medical-management-vs-mechanical-circulatory-support-in-severe-inotrope-dependent-acute-heart-failure
#20
Anna J Meredith, Darlene L Y Dai, Virginia Chen, Zsuzsanna Hollander, Raymond Ng, Annemarie Kaan, Scott Tebbutt, Krishnan Ramanathan, Anson Cheung, Bruce M McManus
BACKGROUND: Severe inotrope-dependent acute heart failure (AHF) is associated with poor clinical outcomes. There are currently no well-defined blood biomarkers of response to treatment that can guide management or identify recovery in this patient population. In the present study, we characterized the levels of novel and emerging circulating biomarkers of heart failure in patients with AHF over the first 30 days of medical management or mechanical circulatory support (MCS). We hypothesized a shared a plasma proteomic treatment response would be identifiable in both patient groups, representing reversal of the AHF phenotype...
June 2016: ESC Heart Failure
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