David M Smadja, Richard Chocron, Elisa Rossi, Bastien Poitier, Yuri Pya, Mahabbat Bekbossynova, Christophe Peronino, Jeanne Rancic, Jean Christian Roussel, Michel Kindo, Nicolas Gendron, Ludovica Migliozzi, Antoine Capel, Jean Christophe Perles, Pascale Gaussem, Peter Ivak, Piet Jansen, Claude Girard, Alain Carpentier, Christian Latremouille, Coralie Guerin, Ivan Netuka
Pulsatile Carmat bioprosthetic total artificial heart (C-TAH) is designed to be implanted in patients with biventricular end-stage heart failure. Since flow variation might contribute to endothelial dysfunction, we explored circulating endothelial biomarkers after C-TAH implantation in seven patients and compared the manual and autoregulated mode. Markers of endothelial dysfunction and regeneration were compared before and during a 6- to 9-month follow-up after implantation. The follow-up was divided into three periods (< 3, 3-6, and > 6 months) and used to estimate the temporal trends during the study period...
July 20, 2020: Thrombosis and Haemostasis