keyword
MENU ▼
Read by QxMD icon Read
search

dcp

keyword
https://www.readbyqxmd.com/read/28527381/enantioselectivity-of-haloalkane-dehalogenase-linb-on-the-degradation-of-1-2-dichloropropane-a-qm-mm-study
#1
Xiaowen Tang, Ruiming Zhang, Yanwei Li, Qingzhu Zhang, Wenxing Wang
The hydrolysis dechlorination mechanism of a chiral organochlorinepollutant, 1,2-dichloropropane (DCP), catalyzed by haloalkane dehalogenase LinB has been investigated by using a combined quantum mechanics/molecular mechanics method. LinB was confirmed to be enantioselective towards the catabolism of the racemic mixture. Based on the SN2 nucleophilic substitution mechanism, the dechlorination process was identified as the rate-determining step in LinB-catalyzed degradation of 1,2-dichloropropane, the Boltzmann-weighted average potential barrier of which is 18...
May 12, 2017: Bioorganic Chemistry
https://www.readbyqxmd.com/read/28522828/efficient-wideband-numerical-simulations-for-nanostructures-employing-a-drude-critical-points-dcp-dispersive-model
#2
Qiang Ren, Jogender Nagar, Lei Kang, Yusheng Bian, Ping Werner, Douglas H Werner
A highly efficient numerical approach for simulating the wideband optical response of nano-architectures comprised of Drude-Critical Points (DCP) media (e.g., gold and silver) is proposed and validated through comparing with commercial computational software. The kernel of this algorithm is the subdomain level discontinuous Galerkin time domain (DGTD) method, which can be viewed as a hybrid of the spectral-element time-domain method (SETD) and the finite-element time-domain (FETD) method. An hp-refinement technique is applied to decrease the Degrees-of-Freedom (DoFs) and computational requirements...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28521016/influence-of-gsh-s-transferase-on-the-mutagenicity-induced-by-dichloromethane-and-1-2-dichloropropane
#3
Nozomi Akiba, Kazuhiro Shiizaki, Yoshitaka Matsushima, Osamu Endo, Kazuho Inaba, Yukari Totsuka
It has been suggested that dichloromethane (DCM) and 1,2-dichloropropane (DCP) are responsible for occupational cholangiocarcinoma. Dihaloalkanes are metabolically activated by GSH S-transferase theta1 (GSTT1) to yield products such as episulfonium ions. However, whether the GSTT1-mediated step of these dihaloalkanes is related to occupational cholangiocarcinoma is not known. In the present study, we investigated the influence of GSTT1 activation on the mutagenicity of DCM and 1,2-DCP using GSTT1-expressing Salmonella typhimurium TA100 (TA100-GST)...
May 17, 2017: Mutagenesis
https://www.readbyqxmd.com/read/28515937/dicyano-and-tetracyanopentacene-foundation-of-an-intriguing-new-class-of-easy-to-synthesize-organic-semiconductors
#4
Florian Glöcklhofer, Andreas Petritz, Esther Karner, Michael J Bojdys, Barbara Stadlober, Johannes Fröhlich, Miriam M Unterlass
Cyanated pentacenes are very promising candidate materials for ambipolar and n-type transistors. However, only a few examples have been obtained to date - all requiring lengthy, multi-step processes. Herein, we present the first preparation of 5,7,12,14-tetracyanopentacene (TCP) and a facile, scaled-up preparation of 6,13-dicyanopentacene (DCP). Both compounds are prepared by a one-pot synthesis using cheap quinones as starting materials. Detailed crystallographic investigations evince that the bulk assemblies of both cyanated pentacenes are dominated by non-covalent interactions, resulting in a dense, stable, face-to-face packing and in an intriguing packing motif for TCP...
March 14, 2017: Journal of Materials Chemistry. C, Materials for Optical and Electronic Devices
https://www.readbyqxmd.com/read/28501447/comparison-of-quantitative-measurement-of-foveal-avascular-zone-and-macular-vessel-density-in-eyes-of-children-with-amblyopia-and-healthy-controls-an-optical-coherence-tomography-angiography-study
#5
Ihsan Yilmaz, Osman Bulut Ocak, Basak Saracoglu Yilmaz, Aslı Inal, Birsen Gokyigit, Muhittin Taskapili
PURPOSE: To quantify vessel density of superficial capillary plexus (SCP), deep capillary plexus (DCP), and the foveal avascular zone (FAZ) of children's amblyopic eyes and to compare the measurements with those of companion eyes and age-matched controls. METHODS: Fifteen patients with strabismic amblyopia, and 15 age-matched controls were included in this cross-sectional study. SCP, DCP, and FAZ were measured via optical coherence tomographic angiography (OCTA)...
May 10, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28489918/oct-angiography-a-qualitative-and-quantitative-comparison-of-4-oct-a-devices
#6
Marion R Munk, Helena Giannakaki-Zimmermann, Lieselotte Berger, Wolfgang Huf, Andreas Ebneter, Sebastian Wolf, Martin S Zinkernagel
PURPOSE: To compare the quality of four OCT-angiography(OCT-A) modules. METHOD: The retina of nineteen healthy volunteers were scanned with four OCT-devices (Topcon DRI-OCT Triton Swept-source OCT, Optovue RTVue-XR, a prototype Spectralis OCT2, Heidelberg-Engineering and Zeiss Cirrus 5000-HD-OCT). The device-software generated en-face OCT-A images of the superficial (SCP) and deep capillary plexuses (DCP) were evaluated and scored by 3 independent retinal imaging experts...
2017: PloS One
https://www.readbyqxmd.com/read/28484419/altered-functional-connectivity-of-striatal-subregions-in-patients-with-multiple-sclerosis
#7
Fangyuan Cui, Li Zhou, Zengjian Wang, Courtney Lang, Joel Park, Zhongjian Tan, Yao Yu, Chunyan Sun, Ying Gao, Jian Kong
Abnormal corticostriatal resting-state functional connectivity (rsFC) has been implicated in the neuropathology of multiple sclerosis. The striatum, a component of the basal ganglia, is involved in diverse functions including movement, cognition, emotion, and limbic information processing. However, the brain circuits of the striatal subregions contributing to the changes in rsFC in relapsing-remitting multiple sclerosis (RRMS) patients remain unknown. We used six subdivisions of the striatum in each hemisphere as seeds to investigate the rsFC of striatal subregions between RRMS patients and matched healthy controls (HCs)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28483496/relationship-between-internal-reflectivity-of-diabetic-microaneurysms-on-sd-oct-and-detection-on-oct-angiography
#8
Mariacristina Parravano, Daniele De Geronimo, Fabio Scarinci, Lea Querques, Gianni Virgili, Joseph Michael Simonett, Monica Varano, Francesco Bandello, Giuseppe Querques
PURPOSE: To correlate the appearance of Microaneurysms (MAs) on structural spectral-domain optical coherence tomography (SD-OCT) with their detection on OCT angiography (OCTA) in patients with non-proliferative diabetic retinopathy (NPDR). DESIGN: Inter-instrument reliability study. METHODS: Sixteen patients with NPDR without macular edema underwent SD-OCT and OCTA. To compare MAs seen on OCTA to those on SD-OCT, we superimposed the OCTA superficial capillary plexus (SCP) vascular landmarks onto those of the near infrared...
May 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28482112/a-bayesian-screening-approach-for-hepatocellular-carcinoma-using-multiple-longitudinal-biomarkers
#9
Nabihah Tayob, Francesco Stingo, Kim-Anh Do, Anna S F Lok, Ziding Feng
Advanced hepatocellular carcinoma (HCC) has limited treatment options and poor survival, therefore early detection is critical to improving the survival of patients with HCC. Current guidelines for high-risk patients include ultrasound screenings every six months, but ultrasounds are operator dependent and not sensitive for early HCC. Serum α-Fetoprotein (AFP) is a widely used diagnostic biomarker, but it has limited sensitivity and is not elevated in all HCC cases so, we incorporate a second blood-based biomarker, des'γ carboxy-prothrombin (DCP), that has shown potential as a screening marker for HCC...
May 8, 2017: Biometrics
https://www.readbyqxmd.com/read/28474119/optical-coherence-tomography-angiography-analysis-of-retinal-vascular-plexuses-and-choriocapillaris-in-patients-with-type-1-diabetes-without-diabetic-retinopathy
#10
Adriano Carnevali, Riccardo Sacconi, Eleonora Corbelli, Livia Tomasso, Lea Querques, Gianpaolo Zerbini, Vincenzo Scorcia, Francesco Bandello, Giuseppe Querques
AIMS: To analyze retinal vascular plexuses and choriocapillaris by optical coherence tomography angiography (OCT-A) and retinal nerve fiber layer and ganglion cell layer (GCL) by structural optical coherence tomography (OCT) in patients with type 1 diabetes mellitus (T1DM) without diabetic retinopathy (DR). METHODS: A total of 25 eyes of 25 consecutive T1DM patients without signs of DR were prospectively recruited and compared to 25 healthy subjects (control eyes)...
May 5, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28458303/prognostic-impact-of-indocyanine-green-plasma-disappearance-rate-in-hepatocellular-carcinoma-patients-after-radiofrequency-ablation-a-prognostic-nomogram-study
#11
Motoi Azumi, Takeshi Suda, Shuji Terai, Kouhei Akazawa
Objective Radiofrequency ablation has been used widely for the local ablation of hepatocellular carcinoma, particularly in its early stages. The study aim was to identify significant prognostic factors and develop a predictive nomogram for patients with hepatocellular carcinoma who have undergone radiofrequency ablation. We also developed the formula to predict the probability of 3- and 5-year overall survival based on clinical variables. Methods We retrospectively studied 96 consecutive patients with hepatocellular carcinoma who had undergone radiofrequency ablation as a first-line treatment...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28450258/effects-of-wastewater-treatment-processes-on-the-sludge-reduction-system-with-2-4-dichlorophenol-sequencing-batch-reactor-and-anaerobic-anoxic-oxic-process
#12
Yunping Han, Yongli Sun, Hong Chen, Xuesong Guo, Chuanyang Yu, YanBo Li, Junxin Liu, Benyi Xiao
The effects of two wastewater treatment processes (sequencing batch reactor, SBR; and anaerobic-anoxic-oxic, A2O) on sludge reduction with metabolic uncoupler 2,4-dichlorophenol (DCP) were studied in laboratory. The experimental results showed that the reduction of cumulative excess sludge in SBR and A2O was 43.7% and 44.2%, respectively, during the stable stage of the test. The two processes had similar average sludge yield and sludge yield reduction, i.e., 0.306 and 0.305mg of SS/mg chemical oxygen demand (COD), and 16...
April 24, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28436440/a-metallic-molybdenum-dioxide-with-high-stability-for-surface-enhanced-raman-spectroscopy
#13
Qiqi Zhang, Xinshi Li, Qiang Ma, Qing Zhang, Hua Bai, Wencai Yi, Jingyao Liu, Jing Han, Guangcheng Xi
Compared with noble metals, semiconductors with surface plasmon resonance effect are another type of SERS substrate materials. The main obstacles so far are that the semiconducting materials are often unstable and easy to be further oxidized or decomposed by laser irradiating or contacting with corrosive substances. Here, we report that metallic MoO2 can be used as a SERS substrate to detect trace amounts of highly risk chemicals including bisphenol A (BPA), dichloropheno (DCP), pentachlorophenol (PCP) and so on...
April 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28434228/rapid-biodegradation-of-the-herbicide-2-4-dichlorophenoxyacetic-acid-by-cupriavidus-gilardii-t-1
#14
Xiangwei Wu, Wenbo Wang, Junwei Liu, Dandan Pan, Xiaohui Tu, Pei Lv, Yi Wang, Haiqun Cao, Yawen Wang, Rimao Hua
Phytotoxicity and environmental pollution of residual herbicides have caused much public concern during the past several decades. An indigenous bacterial strain capable of degrading 2,4-dichlorophenoxyacetic acid (2,4-D), designated T-1, was isolated from soybean field soil and identified as Cupriavidus gilardii. Strain T-1 degraded 2,4-D 3.39 times more rapidly than the model strain Cupriavidus necator JMP134. T-1 could also efficiently degrade 2-methyl-4-chlorophenoxyacetic acid (MCPA), MCPA isooctyl ester, and 2-(2,4-dichlorophenoxy)propionic acid (2,4-DP)...
May 1, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28418226/serum-monomeric-laminin-%C3%AE-2-as-a-novel-biomarker-for-hepatocellular-carcinoma
#15
Hirofumi Kiyokawa, Hiroshi Yasuda, Ritsuko Oikawa, Chiaki Okuse, Nobuyuki Matsumoto, Hiroki Ikeda, Tsunamasa Watanabe, Hiroyuki Yamamoto, Fumio Itoh, Takehito Otsubo, Toru Yoshimura, Eisaku Yoshida, Masatoshi Nakagawa, Naohiko Koshikawa, Motoharu Seiki
The diagnosis of hepatocellular carcinoma (HCC) in the early stages is important for successful clinical management. Laminin (Ln)-γ2 expression has been reported in various types of malignant carcinomas. We recently developed a highly sensitive method to measure serum monomeric Ln-γ2 levels using a fully automated chemiluminescent immunoassay (CLIA). Using our CLIA, we evaluated its diagnostic value in sera from patients with chronic liver disease (CLD) and patients with hepatocellular carcinoma (HCC). Serum alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) were also examined in these subjects...
April 18, 2017: Cancer Science
https://www.readbyqxmd.com/read/28416262/use-of-dilute-ammonia-gas-for-treatment-of-1-2-3-trichloropropane-and-explosives-contaminated-soils
#16
Charles G Coyle, Scott A Waisner, Victor F Medina, Chris S Griggs
Laboratory studies were performed to test a novel reactive gas process for in-situ treatment of soils containing halogenated propanes or explosives. A soil column study, using a 5% ammonia-in-air mixture, established that the treatment process can increase soil pH from 7.5 to 10.2. Batch reactor experiments were performed to demonstrate contaminant destruction in sealed jars exposed to ammonia. Comparison of results from batch reactors that were, and were not, exposed to ammonia demonstrated reductions in concentrations of 1,2,3-trichloropropane (TCP), 1,3-dichloropropane (1,3-DCP), 1,2-dicholoropropane (1,2-DCP) and dibromochloropropane (DBCP) that ranged from 34 to 94%...
April 14, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28400062/adm-guidance-ceramics-guidance-to-the-use-of-fractography-in-failure-analysis-of-brittle-materials
#17
Susanne S Scherrer, Ulrich Lohbauer, Alvaro Della Bona, Alessandro Vichi, Michael J Tholey, J Robert Kelly, Richard van Noort, Paulo Francisco Cesar
OBJECTIVES: To provide background information and guidance as to how to use fractography accurately, a powerful tool for failure analysis of dental ceramic structures. METHODS: An extended palette of qualitative and quantitative fractography is provided, both for in vivo and in vitro fracture surface analyses. As visual support, this guidance document will provide micrographs of typical critical ceramic processing flaws, differentiating between pre- versus post sintering cracks, grinding damage related failures and occlusal contact wear origins and of failures due to surface degradation...
April 8, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28388705/retinal-microvasculature-and-visual-acuity-in-eyes-with-branch-retinal-vein-occlusion-imaging-analysis-by-optical-coherence-tomography-angiography
#18
Taku Wakabayashi, Tatsuhiko Sato, Chikako Hara-Ueno, Yoko Fukushima, Kaori Sayanagi, Nobuhiko Shiraki, Miki Sawa, Yasushi Ikuno, Hirokazu Sakaguchi, Kohji Nishida
Purpose: To investigate microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in eyes with resolved branch retinal vein occlusion (BRVO) and their association with best-corrected visual acuity (BCVA). Methods: Eighty-five eyes (82 consecutive patients) with BRVO after resolution of the macular edema were retrospectively evaluated. All patients underwent optical coherence tomography angiography (OCTA) for assessment of microvascular changes, including capillary telangiectasia, microaneurysm, and disruption of the foveal avascular zone (FAZ)...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28384724/gap-in-capillary-perfusion-on-optical-coherence-tomography-angiography-associated-with-persistent-macular-edema-in-branch-retinal-vein-occlusion
#19
Kotaro Tsuboi, Yuichiro Ishida, Motohiro Kamei
Purpose: To evaluate correlations between persistent macular edema associated with branch retinal vein occlusion (BRVO) and the macular perfusion status in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) using optical coherence tomography angiography (OCTA). Methods: Retrospective, case-control study. Twenty patients with BRVO followed for 12 months or more were enrolled. Persistent macular edema was defined as central retinal thickness exceeding 300 μm that persisted or recurred less than 3 months after the final treatment...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28384634/poly-adp-ribose-polymerase-1-promotes-prothrombin-gene-transcription-and-produces-des-gamma-carboxy-prothrombin-in-hepatocellular-carcinoma
#20
Tatsuya Taniguchi, Kazuhiro Kishi, Tadahiko Nakagawa, Hironori Tanaka, Takahiro Tanaka, Tetsu Tomonari, Koichi Okamoto, Masahiro Sogabe, Hiroshi Miyamoto, Toshiya Okahisa, Naoki Muguruma, Mayumi Kajimoto, Ikuko Sagawa, Tetsuji Takayama
BACKGROUND AND AIM: Although des-gamma-carboxy prothrombin (DCP) is a well-known tumor marker for hepatocellular carcinoma (HCC), the mechanism of DCP production is unclear. This study aimed to investigate the mechanism how DCP is produced in HCC cells. METHODS: Levels of mRNA and DCP were analyzed by real-time polymerase chain reaction and electro-chemiluminescence immunoassay respectively. Secreted alkaline phosphatase (SEAP) expression vectors including deletion mutants of the prothrombin gene promoter were constructed for reporter gene assay...
April 7, 2017: Digestion
keyword
keyword
66812
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"