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https://www.readbyqxmd.com/read/29331621/silver-ion-enhanced-particle-specific-cytotoxicity-of-silver-nanoparticles-and-effect-on-the-production-of-extracellular-secretions-of-phanerochaete-chrysosporium
#1
Zhenzhen Huang, Piao Xu, Guiqiu Chen, Guangming Zeng, Anwei Chen, Zhongxian Song, Kai He, Lei Yuan, Hui Li, Liang Hu
This study investigated the influence of silver ions (Ag+) on the cytotoxicity of silver nanoparticles (AgNPs) in Phanerochaete chrysosporium and noted the degree of extracellular secretions in response to the toxicant's stress. Oxalate production was elicited with moderate concentrations of 2,4-dichlorophenol (2,4-DCP) and AgNPs reaching a plateau at 10 mg/L and 10 μM, respectively. Increased oxalate accumulation was accompanied by higher activities of manganese peroxidase (MnP) and lignin peroxidase (LiP)...
December 30, 2017: Chemosphere
https://www.readbyqxmd.com/read/29330532/methanobactin-from-methylosinus-trichosporium-ob3b-inhibits-n2o-reduction-in-denitrifiers
#2
Jin Chang, Wenyu Gu, Doyoung Park, Jeremy D Semrau, Alan A DiSpirito, Sukhwan Yoon
Methanotrophs synthesize methanobactin, a secondary metabolite that binds copper with an unprecedentedly high affinity. Such a strategy may provide methanotrophs a "copper monopoly" that can inhibit the activity of copper-containing enzymes of other microbes, e.g., copper-dependent N2O reductases. Here, we show that methanobactin from Methylosinus trichosporium OB3b inhibited N2O reduction in denitrifiers. When Pseudomonas stutzeri DCP-Ps1 was incubated in cocultures with M. trichosporium OB3b or with purified methanobactin from M...
January 12, 2018: ISME Journal
https://www.readbyqxmd.com/read/29320855/sensitive-detection-of-a-nerve-agent-simulant-through-retightening-internanofiber-binding-for-fluorescence-enhancement
#3
Xiaoling Liu, Yanjun Gong, Yingxuan Zheng, Wei Xiong, Chen Wang, Tie Wang, Yanke Che, Jincai Zhao
In this work, we develop fluorescent hierarchical nanofiber bundles 1, which involve the internanofiber hydrogen-bonding interactions, for rapid and sensitive detection of DCP vapor. First, the internanofiber hydrogen-bonding strength can be weakened by photoexcitation, which thereby increases the internanofiber spacing and decreases the fluorescence intensity. Then, when exposed to trace DCP vapor, the strong interactions between DCP and hydroxyl groups on the nanofibers can effectively retighten the nanofibers and enhance the fluorescence as the detection signal...
January 11, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29306213/urinary-metabolites-of-organophosphate-esters-in-children-in-south-china-concentrations-profiles-and-estimated-daily-intake
#4
Yi Chen, Jianzhang Fang, Lu Ren, Ruifang Fan, Jianqing Zhang, Guihua Liu, Li Zhou, Dingyan Chen, Yingxin Yu, Shaoyou Lu
Organophosphate esters (OPEs) are widely used in household products as flame retardants or plasticizers and have become ubiquitous pollutants in environmental media. However, little is known about OPE metabolites in humans, especially in children. In this study, eight OPE metabolites were measured in 411 urine samples collected from 6 to 14-year-old children in South China. Bis(2-chloroethyl) phosphate (BCEP), bis(1-chloro-2-propyl) phosphate (BCIPP) and diphenyl phosphate (DPHP) were the dominant OPE metabolites, and their median concentrations were 1...
January 3, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29305303/alliin-attenuates-1-3-dichloro-2-propanol-induced-lipogenesis-in-hepg2-cells-through-activation-of-the-amp-activated-protein-kinase-dependent-pathway
#5
Jing Lu, Bijun Cheng, Zhuoqun Meng, Baochen Fang, Tianjiao Li, Maocheng Sun, Meitong Liu, Shuang Guan
Accumulating evidence reveals the association of 1, 3-dichloro-2-propanol (1, 3-DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti-inflammatory activities. Here, we showed that alliin attenuated lipogenesis induced by 1,3-DCP and that the reduction was due to activation of the AMPK pathway. HepG2 cells exposed to 1,3-DCP exhibited significant increase of triglyceride(TG) and total cholesterol(TC), and alliin reduced the accumulation...
January 2, 2018: Life Sciences
https://www.readbyqxmd.com/read/29289773/effects-of-bromide-on-the-formation-and-transformation-of-disinfection-by-products-during-chlorination-and-chloramination
#6
Ruiping Liu, Chuan Tian, Chengzhi Hu, Zenglu Qi, Huijuan Liu, Jiuhui Qu
The presence of bromide ion (Br-) complicates the formation of disinfection by-products (DBPs) during chlorination and chloramination greatly. To better illustrate the role of Br-, Br- was introduced at different time intervals, i.e., 0min, 5min, 30min, and 24h, after dosing with chlorine (Cl2) or chloramine (NH2Cl), and the formation of trihalomethanes (THMs), haloacetic acids (HAAs), haloacetonitriles, and haloacetones was investigated during these two disinfection scenarios. Ammonia rapidly reacts with chlorine and forms low-reactivity NH2Cl, and this effect inhibits the formation of these DBPs greatly...
December 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29288639/retinal-vascular-impairment-in-best-vitelliform-macular-dystrophy-assessed-by-means-of-optical-coherence-tomography-angiography
#7
Maurizio Battaglia Parodi, Francesco Romano, Maria Vittoria Cicinelli, Alessandro Rabiolo, Alessandro Arrigo, Luisa Pierro, Pierluigi Iacono, Francesco Bandello
PURPOSE: To evaluate vascular abnormalities at superficial (SCP), deep (DCP) capillary plexuses and choriocapillaris (CC) in patients with Best vitelliform macular dystrophy (BVMD) by means of optical coherence tomography angiography (OCT-A). DESIGN: Cross-sectional case series. METHODS: Sixty-six eyes of 33 patients with BVMD (sixteen males) and 33 controls were consecutively enrolled. Patients were subdivided in classic stages and underwent best-corrected visual acuity (BCVA), fundus autofluorescence and spectral domain-optical coherence tomography (Spectralis HRA+OCT; Heidelberg Engineering), and 4...
December 27, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29284480/creating-research-and-development-awareness-among-dental-care-professionals-by-use-of-strategic-communication-a-12-year-intervention-study
#8
Helena Morténius, Svante Twetman
BACKGROUND: Despite the availability of contemporary research advances, only a limited fraction is implemented into dental practice. One possible way to facilitate this process is to stimulate the research and development (R&D) awareness and interest with aid of strategic communication. METHODS: The aim of the study was to analyse the role of a strategic communication in R&D awareness and interest among dental care professionals (DCP) over a 12-year period. A second aim was to compare the findings with those from primary care professionals (PCP)...
December 29, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29260118/projection-resolved-optical-coherence-tomography-angiography-exhibiting-early-flow-prior-to-clinically-observed-retinal-angiomatous-proliferation
#9
Kavita V Bhavsar, Yali Jia, Jie Wang, Rachel C Patel, Andreas K Lauer, David Huang, Steven T Bailey
Purpose: The purpose of this study is to analyze early retinal angiomatous proliferation (RAP) utilizing a novel imaging modality, Projection-Resolved Optical Coherence Tomography Angiography (PR-OCTA). Observations: Five months prior to the diagnosis of a RAP lesion, cross-sectional PR-OCTA demonstrated flow in the outer retina contiguous with the deep retinal capillary plexus (DCP) and adjacent to a small pigment epithelial detachment. After development of a clinically visible RAP lesion, cross-sectional PR-OCTA demonstrated the RAP lesion connecting DCP and sub-retinal pigment epithelial neovascularization...
December 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29248572/1-3-dichloro-2-propanol-evokes-inflammation-and-apoptosis-in-bv-2-microglia-via-mapks-and-nf-%C3%AE%C2%BAb-signaling-pathways-mediated-by-reactive-oxygen-species
#10
Chunxia Xiao, Pandi He, Jingjing Han, Miaoling Tang, Zhen Wang, Yashi Mi, Xuebo Liu
1,3-dichloro-2-propanol (1,3-DCP) is a widely concerned food processing contaminant which has been investigated for decades. While the neurotoxicity of 1,3-DCP and related mechanisms are still elusive. Herein, the effect of 1,3-DCP on neurotoxicity was investigated using BV-2 microglia cells. 1,3-DCP significantly decreased cell viability from 78.6% to 59.2% at doses between 2 and 20 mM. AO/EB and JC-1 staining indicated that 1,3-DCP induced apoptosis by means of the decrease of mitochondrial membrane potential...
December 14, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29228347/exposure-of-mice-to-1-2-dichloropropane-induces-cyp450-dependent-proliferation-and-apoptosis-of-cholangiocytes
#11
Xiao Zhang, Cai Zong, Lingyi Zhang, Edwin Garner, Shigeyuki Sugie, Chinyen Huang, Wenting Wu, Jie Chang, Toshihiro Sakurai, Masashi Kato, Sahoko Ichihara, Shinji Kumagai, Gaku Ichihara
1, 2-Dichloropropane (1, 2-DCP) has been used as a paint remover in the industry. The International Agency for Research on Cancer reclassified this compound recently to Group 1 (carcinogenic to humans) based on epidemiological studies of cholangiocarcinoma among offset-color proof-printing workers exposed to 1, 2-DCP in Japan. Two-year rodent carcinogenicity bioassays demonstrated that 1, 2-DCP induced tumors in liver and lung, but not in bile duct. The present study was designed to assess the toxic effects of 1, 2-DCP on proliferation and apoptosis in mice bile duct and the role of cytochrome P450 (CYP450) in any such effect...
December 7, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29210691/removing-2-4-dichlorophenol-from-aqueous-environments-by-heterogeneous-catalytic-ozonation-using-synthesized-mgo-nanoparticles
#12
Leili Mohammadi, Edris Bazrafshan, Meissam Noroozifar, Alireza Ansari-Moghaddam, Farahnaz Barahuie, Davoud Balarak
2,4-Dichlorophenol (2,4-DCP) is one of the seriously toxic chlorophenol compounds found in agricultural environments, in water disinfected by chlorine, and in outgoing effluents from the pulp and paper industries and paper manufacturing factories. This research studied the feasibility of using MgO nanoparticles (MgO-NPs) as a catalyst in the ozonation process for removing 2,4-DCP from aqueous environments under laboratory conditions. This study was conducted using a laboratory-scale semi-continuous reactor...
December 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29206758/early-microvascular-and-neural-changes-in-patients-with-type-1-and-type-2-diabetes-mellitus-without-clinical-signs-of-diabetic-retinopathy
#13
Stela Vujosevic, Andrea Muraca, Micol Alkabes, Edoardo Villani, Fabiano Cavarzeran, Luca Rossetti, Stefano De Cillaʼ
PURPOSE: To assess and compare early modifications in inner retinal layer thickness and optical coherence tomography angiography parameters in patients with diabetes mellitus (DM) Types 1 and 2 without clinical signs of diabetic retinopathy. METHODS: Ninety eyes of 90 subjects (24 Type 1 DM, 36 Type 2 DM, and 30 healthy controls) were prospectively evaluated with spectral domain OCT, swept-source OCT angiography, and color fundus photography (on the same day). Retinal nerve fiber layer, ganglion cell layer (GCL+), and nerve fiber layer + GCL+ (GCL++) thickness were automatically determined by the instrument in the 1, 3, and 6 central mm...
December 4, 2017: Retina
https://www.readbyqxmd.com/read/29202508/outcome-of-repair-of-distal-radial-and-ulnar-fractures-in-dogs-weighing-4-kg-or-less-using-a-1-5-mm-locking-adaption-plate-or-2-0-mm-limited-contact-dynamic-compression-plate
#14
Thomas A Nelson, Adam Strom
Objectives Retrospective evaluation of repairing distal radial and ulnar fractures in small breed dogs with the Synthes 1.5-mm locking Adaption plate system and compare results in a similar group of patients repaired with the Synthes 2.0-mm limited contact-dynamic compression plate (LC-DCP). Methods Electronic medical records from one specialty referral centre were reviewed from March 21, 2010, to October 9, 2015, for patients weighing less than or equal to 4 kg that had a distal one-third radial and ulnar fracture repaired with a Synthes 1...
November 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29199314/raman-antenna-effect-from-exciton-phonon-coupling-in-organic-semiconducting-nanobelts
#15
Mao Wang, Yi Gong, Francesc Alzina, Ondrej Svoboda, Belén Ballesteros, Clivia M Sotomayor Torres, Senbo Xiao, Zhiliang Zhang, Jianying He
The highly anisotropic interactions in organic semiconductors together with the soft character of organic materials lead to strong coupling between nuclear vibrations and exciton dynamics, which potentially results in anomalous electrical, optical and optoelectrical properties. Here, we report on the Raman antenna effect from organic semiconducting nanobelts 6,13-dichloropentacene (DCP), resulting from the coupling of molecular excitons and intramolecular phonons. The highly ordered crystalline structure in DCP nanobelts enables the precise polarization-resolved spectroscopic measurement...
December 4, 2017: Nanoscale
https://www.readbyqxmd.com/read/29195103/chromium-zinc-ferrite-nanocomposites-for-the-catalytic-abatement-of-toxic-environmental-pollutants-under-ambient-conditions
#16
Divya S Nair, Manju Kurian
Catalytic abatement of 4-chlorophenol, 2,4-dichlorophenol and 2,4-dichlorophenoxy acetic acid in water was investigated by peroxide oxidation over chromium substituted zinc ferrite nanocomposites at ambient conditions. The structural and chemical properties of composites synthesized by sol-gel auto combustion method was studied by X-ray diffraction, Fourier Transform Infra-Red spectroscopy, Transmission Electron Microscopy, surface area, X-ray Fluorescence spectroscopy, Temperature Programmed Reduction and Desorption techniques...
November 27, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29192630/diagnostic-utility-of-alpha-fetoprotein-and-des-gamma-carboxyprothrombin-in-nigerians-with-hepatocellular-carcinoma
#17
Akpakip Ikpong Ette, D A Ndububa, O Adekanle, U Ekrikpo
BACKGROUND: Alpha-fetoprotein (AFP) and Des-gamma-carboxyprothrombin (DCP) have been extensively studied as biomarkers for the diagnosis of and prognostication in hepatocellular carcinoma (HCC). However there are only few reports on the clinical characteristics of hepatocellular carcinoma in relation to the combination of the two tumor markers in hepatitis B virus-related HCC. AIM: The aim of this study was to investigate the clinical characteristics of HBV-related HCC in relation to different sets of AFP and DCP values...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29188597/association-of-urinary-concentrations-of-four-chlorophenol-pesticides-with-cardiometabolic-risk-factors-and-obesity-in-children-and-adolescents
#18
Saeed Parastar, Karim Ebrahimpour, Majid Hashemi, Mohammad Reza Maracy, Afshin Ebrahimi, Parinaz Poursafa, Roya Kelishadi
This study was undertaken to determine the association of four chlorophenol pesticides with cardiometabolic risk factors and obesity in children and adolescents. This cross-sectional study was conducted in 2016 on 242 children and adolescents, aged 6 to 18 years. The concentrations of 2,4-dichlorophenol (2,4-DCP), 2,5-dichlorophenol (2,5-DCP), 2,4,5-trichlorophenol (2,4,5-TCP), and 2,4,6-trichlorophenol (2,4,6-TCP) in the urine were examined and their association with indices of obesity and cardiometabolic risk factors was determined...
November 29, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29183533/predictive-factors-for-treatment-failure-after-peritoneovenous-shunt-for-hepatic-ascites
#19
Hiroya Iida, Tsukasa Aihara, Shinichi Ikuta, Naoki Yamanaka
Peritoneovenous shunt (PVS) is used to treat refractory ascites. Here, we identify predictive factors for inhospital death after PVS placement. Thirty-five patients with refractory ascites related to liver cirrhosis and/or hepatocellular carcinoma (HCC) who underwent PVS placement between February 2005 and February 2013 were included in the study. Group A comprised 13 patients for whom the PVS placement outcome was inhospital death. Group B comprised 22 patients who were discharged after PVS placement without complications...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29179702/foveal-microvasculature-features-of-surgically-closed-macular-hole-using-optical-coherence-tomography-angiography
#20
Joon Hee Cho, Ho Chul Yi, So Hyun Bae, Hakyoung Kim
BACKGROUND: To describe the features of foveal microvasculature using optical coherence tomography angiography (OCTA) and to determine the related clinical factors in eyes with surgically closed macular hole (MH). METHODS: A retrospective case series of 18 patients with unilateral MH was reviewed. The patients maintained complete hole closure after vitrectomy with inner limiting membrane (ILM) peeling for at least 12 months. The healthy fellow eyes were studied as controls...
November 28, 2017: BMC Ophthalmology
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