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https://www.readbyqxmd.com/read/28531809/multifocal-visual-evoked-potentials-in-optic-neuritis-and-multiple-sclerosis-a-review
#1
REVIEW
Gorm Pihl-Jensen, Mathias Falck Schmidt, Jette Lautrup Frederiksen
Multifocal visual evoked potential (mf-VEP) represents a new approach to the classical full field (ff-)VEP with separate responses from up to 60 sectors of the visual field. A thorough literature survey of the use of mf-VEP in optic neuritis (ON) and multiple sclerosis (MS) is presented (38 published studies were retrieved). Mf-VEP provides direct topographical information of specific lesions and facilitates investigations on structural-functional correlations thus providing new methods for exploring the interplay between demyelination, atrophy and remyelination in MS...
April 11, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28530392/a-hexafluoroquinoxaline-based-polymer-for-nonfullerene-solar-cells-reaching-9-4-efficiency
#2
Shutao Xu, Liuliu Feng, Jun Yuan, Zhi-Guo Zhang, Yongfang Li, Hongjian Peng, Yingping Zou
hrough introducing six fluorine atoms onto quinoxaline (Qx), a new electron acceptor unit-hexafluoroquinoxaline (HFQx) is firstly synthesized. Based on this unit, we synthesize a new donor-acceptor (D-A) copolymer (HFQx-T), which is composed of benzodithiophene (BDT) derivative donor block and an HFQx accepting block. The strong electron-withdrawing properties of fluorine atoms increase significantly the voltage open-circuit (Voc) by tuning the highest occupied molecular orbital (HOMO) energy level. In addition, fluorine atoms enhance the absorption coefficient of the conjugated copolymer and change the film morphology, which implies an increase of the short-circuit current density (Jsc) and fill factor (FF)...
May 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28522073/cell-based-skin-substitutes-accelerate-regeneration-of-extensive-burn-wounds-in-rats
#3
Sadrollah Motamed, Ehsan Taghiabadi, Hojjat Molaei, Niloofar Sodeifi, Seyed Esmaeil Hassanpour, Saeed Shafieyan, Enzollah Azargashb, Fatemeh Farajzadeh-Vajari, Nasser Aghdami, Amir Bajouri
BACKGROUND: This study investigated the effects of amniotic membrane combined with adipose-derived stem cells or fetal fibroblasts on regenerating extensive burns in rats. METHODS: Third degree burns of 1100-1800 mm(2) were induced on 32 Sprague-Dawley rats. Burned sites were excised and randomly covered with Vaseline gauze (control), human amniotic membrane (HAM), human fetal fibroblasts seeded on HAM (HAM-FF), or human adipose-derived stem cells seeded on HAM (HAM-ASC), and followed by wound closure and histological assessments...
April 27, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28521606/can-video-self-modeling-improve-affected-limb-reach-and-grasp-ability-in-stroke-patients
#4
Kylie Ann Steel, Kurt Mudie, Remi Sandoval, David Anderson, Sera Dogramaci, Mohammad Rehmanjan, Ingvars Birznieks
The authors examined whether feedforward video self-modeling (FF VSM) would improve control over the affected limb, movement self-confidence, movement self-consciousness, and well-being in 18 stroke survivors. Participants completed a cup transport task and 2 questionnaires related to psychological processes pre- and postintervention. Pretest video footage of the unaffected limb performing the task was edited to create a best-of or mirror-reversed training DVD, creating the illusion that patients were performing proficiently with the affected limb...
May 19, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28521451/dosimetric-comparison-of-intensity-modulated-radiation-therapy-and-volumetric-modulated-arc-therapy-plans-for-the-treatment-of-glioma-using-flattening-filter-free-and-flattening-filter-modes
#5
Dandan Xu, Fei Jia, Guowen Li, Hongfei Li
In the present study, the dose verification between 6X and 6X flattening filter-free (FFF) in intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) was compared, and the advantages and disadvantages of different radiotherapy plans were evaluated. All four plans achieved comparable heterogeneity and conformity indices. For frontal tumor, VMAT demonstrated more improved sparing of the brainstem compared with the IMRT (P=0.045); while in the model of FFF, the Dmax of eye lens was significantly reduced by 16-21% (P<0...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28515458/floccular-fossa-size-is-not-a-reliable-proxy-of-ecology-and-behaviour-in-vertebrates
#6
S Ferreira-Cardoso, R Araújo, N E Martins, G G Martins, S Walsh, R M S Martins, N Kardjilov, I Manke, A Hilger, R Castanhinha
The cerebellar floccular and parafloccular lobes are housed in fossae of the periotic region of the skull of different vertebrates. Experimental evidence indicates that the lobes integrate visual and vestibular information and control the vestibulo-ocular reflex, vestibulo-collic reflex, smooth pursuit and gaze holding. Multiple paleoneuroanatomy studies have deduced the behaviour of fossil vertebrates by measuring the floccular fossae (FF). These studies assumed that there are correlations between FF volume and behaviour...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28514925/factors-affecting-cell-free-dna-fetal-fraction-and-the-consequences-for-test-accuracy
#7
Fergus Perry Scott, Melody Menezes, Ricardo Palma-Dias, Debbie Nisbet, Philip Schluter, Fabricio da Silva Costa, Andrew Cameron McLennan
INTRODUCTION: Biological factors are known to influence the fetal fraction (FF) of cell-free DNA and may also influence the accuracy of non-invasive prenatal testing. MATERIAL AND METHODS: NIPT from 5,267 mixed risk women across three specialist clinics in Australia were analysed. Multivariable regression analysis was used to determine whether maternal characteristics, ultrasound and placental biomarkers affect FF and test accuracy. RESULTS: FF ranged from 4% - 37% (mean 11...
May 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28505528/acuity-in-ranging-based-on-delay-tuned-combination-sensitive-neurons-in-the-auditory-cortex-of-mustached-bats
#8
Masakiyo Suzuki, Nobuo Suga
A 1.0-ms echo delay from an emitted bio-sonar pulse at 25 °C corresponds to a 17.3-cm target distance. In the auditory cortex of the mustached bat, Pteronotus parnellii, neurons tuned to a specific delay (best delay) of an echo from an emitted pulse are clustered in the FF, dorsal fringe and ventral fringe areas. ("FF" stands for the frequency-modulated components of a pulse and its echo.) Those delay-tuned neurons are systematically arranged in the FF area according to their best delays and form a 18-ms-long delay axis...
May 2, 2017: Hearing Research
https://www.readbyqxmd.com/read/28502900/nuclear-morphometry-in-histological-specimens-of-canine-prostate-cancer-correlation-with-histological-subtypes-gleason-score-methods-of-collection-and-survival-time
#9
Guido Di Donato, Renée Laufer-Amorim, Chiara Palmieri
Ten normal prostates, 22 benign prostatic hyperplasia (BPH) and 29 prostate cancer (PC) were morphometrically analyzed with regard to mean nuclear area (MNA), mean nuclear perimeter (MNP), mean nuclear diameter (MND), coefficient of variation of the nuclear area (NACV), mean nuclear diameter maximum (MDx), mean nuclear diameter minimum (MDm), mean nuclear form ellipse (MNFe) and form factor (FF). The relationship between nuclear morphometric parameters and histological type, Gleason score, methods of sample collection, presence of metastases and survival time of canine PC were also investigated...
May 6, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28499814/selected-cholesterol-biosynthesis-inhibitors-produce-accumulation-of-the-intermediate-ff-mas-that-targets-nucleus-and-activates-lxr%C3%AE-in-hepg2-cells
#10
Leonardo Gatticchi, Bruno Cerra, Paolo Scarpelli, Lara Macchioni, Bartolomeo Sebastiani, Antimo Gioiello, Rita Roberti
Sterol intermediates of the cholesterol biosynthetic pathway have drawn attention for novel biological activities. Follicular fluid meiosis activating sterol (FF-MAS) is a LXRα ligand and a potential modulator of physiologic processes regulated by nuclear receptors, such as lipid homeostasis and cell proliferation. In this work, we established a model to selectively accumulate FF-MAS in HepG2 cells, by using a combination of the inhibitors AY9944 and 17-hydroxyprogesterone to block C14-sterol reductases and the downstream C4-demethylase complex...
May 9, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28497416/internal-medicine-point-of-care-ultrasound-curriculum-consensus-recommendations-from-the-canadian-internal-medicine-ultrasound-cimus-group
#11
Irene W Y Ma, Shane Arishenkoff, Jeffrey Wiseman, Janeve Desy, Jonathan Ailon, Leslie Martin, Mirek Otremba, Samantha Halman, Patrick Willemot, Marcus Blouw
Bedside point-of-care ultrasound (POCUS) is increasingly used to assess medical patients. At present, no consensus exists for what POCUS curriculum is appropriate for internal medicine residency training programs. This document details the consensus-based recommendations by the Canadian Internal Medicine Ultrasound (CIMUS) group, comprising 39 members, representing 14 institutions across Canada. Guiding principles for selecting curricular content were determined a priori. Consensus was defined as agreement by at least 80% of the members on POCUS applications deemed appropriate for teaching and assessment of trainees in the core (internal medicine postgraduate years [PGY] 1-3) and expanded (general internal medicine PGY 4-5) training programs...
May 11, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28497162/cadaver-embalming-fluid-for-surgical-training-courses-modified-larssen-solution
#12
Okan Bilge, Servet Celik
PURPOSE: 10% Formalin (F10)-fixed cadavers have disadvantages such as disturbing smell, mucosal irritation, discoloration and rigidity. We aimed to determine a suitable, simple and cost-effective embalming method that preserves color, texture, pliability and flexibility of the tissues for a long time without a disturbing smell and mucosal irritation. The embalmed cadavers were expected to be durable against environmental effects, utilizable for multiple and repetitive surgical trainings and instrumentations...
May 11, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28497040/metabolic-syndrome-and-hypertension-resulting-from-fructose-enriched-diet-in-wistar-rats
#13
Julie Dupas, Annie Feray, Christelle Goanvec, Anthony Guernec, Nolwenn Samson, Pauline Bougaran, François Guerrero, Jacques Mansourati
Increased sugar consumption, especially fructose, is strongly related to the development of type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long term effects of fructose supplementation on Wistar rats. Three-week-old male rats were randomly divided into 2 groups: control (C; n = 14) and fructose fed (FF; n = 18), with a fructose enriched drink (20-25% w/v fructose in water) for 21 weeks. Systolic blood pressure, fasting glycemia, and bodyweight were regularly measured. Glucose tolerance was evaluated three times using an oral glucose tolerance test...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28492361/influence-of-rs2228570-on-transcriptional-activation-by-the-vitamin-d-receptor-in-human-gingival-fibroblasts-and-periodontal-ligament-cells
#14
Kaining Liu, Bing Han, Huanxin Meng, Jianxia Hou
BACKGROUND: Rs2228570 is the only known single nucleotide polymorphism of the vitamin D receptor (VDR) that alters the protein structure. VDRs can be distinguished using the restriction endonuclease FokI, and accordingly divided into three genotypes: FF, Ff and ff. The influence of rs2228570 on transcriptional activation by VDR in human gingival fibroblasts (hGFs) and periodontal ligament cells (hPDLCs) was investigated in this study. METHODS: hGFs and hPDLCs from 15 donors were cultured, genomic DNA was extracted, and genotypes were determined using the PCR-RFLP method...
May 11, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28491935/numerical-dataset-for-analyzing-the-performance-of-a-highly-efficient-ultrathin-film-cdte-solar-cell
#15
Rucksana Safa Sultana, Ali Newaz Bahar, Md Asaduzzaman, Mohammad Maksudur Rahman Bhuiyan, Kawsar Ahmed
The article comprises numerical data of distinct semiconductor materials applied in the sketch of a CdTe absorber based ultrathin film solar cell. Additionally, the contact layer parametric values of the cell have been described also. Therefore, the simulation has been conducted with data related to the hetero-structured (n-ZnO/n-CdS/p-CdTe/p-ZnTe) semiconductor device and a J-V characteristics curve was obtained. The operating conditions have also been recorded. Afterward, the solar cell performance parameters such as open circuit voltage (Voc), short circuit current density (Jsc), fill factor (FF), and efficiency (η) have been investigated and compared with reference cell...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28488430/side-chain-influence-of-wide-bandgap-copolymers-based-on-naphtho-1-2-b-5-6-b-bispyrazine-and-benzo-1-2-b-4-5-b-dithiophene-for-efficient-photovoltaic-applications
#16
Ting Yu, Xiaopeng Xu, Ying Li, Zuojia Li, Qiang Peng
In this work, we reported new types of wide bandgap copolymers, PBDTA-NPz, PBDTT-NPz, PBDTF-NPz and PBDTP-NPz, based on naphtho[1,2-b:5,6-b]bispyrazine (NPz) acceptor building block for efficient photovoltaic applications. The effect of side chains on the properties of these copolymers were investigated in detail, including alkoxyl, alkylthienyl, alkylphenyl and alkylfuryl. These copolymers possessed wide bandgaps from 1.79 eV to 1.88 eV with different non-conjugated or conjugated side chains. They also exhibited low-lying HOMO energy levels below -5...
May 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28483618/perigraft-seroma-after-extra-anatomic-bypass-case-series-and-review-of-the-literature
#17
REVIEW
Daniele Bissacco, Maurizio Domanin, Silvia Romagnoli, Livio Gabrielli
AIM: extra-anatomic bypass (EAB) remains a viable alternative for lower limbs revascularization if aorto-bifemoral bypass and endovascular therapy are contraindicated. Among EAB, periprosthetic seroma (PS) occurs in about 4% of cases. Diagnostic and therapeutic management, as well as standardized treatment paradigm, are still not well defined. The aim of this study is to report 5 PS cases in EAB and to review literature about similar cases. METHODS: We retrospectively reviewed EAB performed during the period 2002-2015...
May 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28483464/urinary-albumin-excretion-and-chronic-kidney-disease-in-children-with-vesicoureteral-reflux
#18
Romaine de Sépibus, François Cachat, Blaise J Meyrat, Gezim Dushi, Ariane Boubaker, Mohamed Faouzi, Eric Girardin, Hassib Chehade
BACKGROUND: Albuminuria is a potential biomarker of chronic kidney disease (CKD) in various glomerular diseases. Vesicoureteral reflux (VUR) often progresses to CKD, and study is required of use of albuminuria as a biomarker for this condition. The aim of this study was to evaluate the association between albuminuria and glomerular filtration rate (GFR) or filtration fraction (FF) in children with VUR. STUDY DESIGN: In this retrospective study, renal parameters of 141 children with VUR were investigated, using inulin clearance, FF, and albuminuria...
April 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28481722/ems-provider-perceptions-on-termination-of-resuscitation-in-a-large-urban-ems-system
#19
Katie L Tataris, Christopher T Richards, Leslee Stein-Spencer, Stephanie Ryan, Pete Lazzara, Joseph M Weber
OBJECTIVE: Despite the value of out-of-hospital Termination of Resuscitation (TOR) and the scientific evidence in favor of this practice, TOR has not been uniformly adopted or consistently practiced in EMS systems. Previous focus group studies have identified multiple barriers to implementation of out of hospital TOR but existing literature on EMS provider perceptions is limited. We sought to identify EMS providers' perceived barriers to performing out-of-hospital TOR in a large urban EMS system...
May 8, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28477007/tissue-recommendations-for-precision-cancer-therapy-using-next-generation-sequencing-a-comprehensive-single-cancer-center-s-experiences
#20
Minho Cho, Soomin Ahn, Mineui Hong, Heejin Bang, Michael Van Vrancken, Seungtae Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Jong-Mu Sun, Se Hoon Lee, Myung-Ju Ahn, Keunchil Park, Duk Hwan Kim, Seunggwan Lee, Woongyang Park, Kyoung-Mee Kim
To generate accurate next-generation sequencing (NGS) data, the amount and quality of DNA extracted is critical. We analyzed 1564 tissue samples from patients with metastatic or recurrent solid tumor submitted for NGS according to their sample size, acquisition method, organ, and fixation to propose appropriate tissue requirements.Of the 1564 tissue samples, 481 (30.8%) consisted of fresh-frozen (FF) tissue, and 1,083 (69.2%) consisted of formalin-fixed paraffin-embedded (FFPE) tissue. We obtained successful NGS results in 95...
April 18, 2017: Oncotarget
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