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https://www.readbyqxmd.com/read/29471275/frequency-agile-gyrotron-for-electron-decoupling-and-pulsed-dynamic-nuclear-polarization
#1
Faith J Scott, Edward P Saliba, Brice J Albert, Nicholas Alaniva, Erika L Sesti, Chukun Gao, Natalie C Golota, Eric J Choi, Anil P Jagtap, Johannes J Wittmann, Michael Eckardt, Wolfgang Harneit, Björn Corzilius, Snorri Th Sigurdsson, Alexander B Barnes
We describe a frequency-agile gyrotron which can generate frequency-chirped microwave pulses. An arbitrary waveform generator (AWG) within the NMR spectrometer controls the microwave frequency, enabling synchronized pulsed control of both electron and nuclear spins. We demonstrate that the acceleration of emitted electrons, and thus the microwave frequency, can be quickly changed by varying the anode voltage. This strategy results in much faster frequency response than can be achieved by changing the potential of the electron emitter, and does not require a custom triode electron gun...
February 12, 2018: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/29457352/controllable-bipolar-doping-of-graphene-with-2d-molecular-dopants
#2
Boseok Kang, Haena Kim, Joong Tark Han, Dae Gun Kim, Kilwon Cho
The fine control of graphene doping levels over a wide energy range remains a challenging issue for the electronic applications of graphene. Here, the controllable doping of chemical vapor deposited graphene, which provides a wide range of energy levels (shifts up to ± 0.5 eV), is demonstrated through physical contact with chemically versatile graphene oxide (GO) sheets, a 2D dopant that can be solution-processed. GO sheets are a p-type dopant due to their abundance of electron-withdrawing functional groups...
February 19, 2018: Small
https://www.readbyqxmd.com/read/29449118/shot-by-a-gun-%C3%A2-missed-by-a-provider
#3
Eddie Garcia, Abdul H Zaid, Diane P Calello, Lisa McHugh, Grant Arzumanov, Najaf Asrar, Ari Sapin, Kristin G Fless
BACKGROUND: Botulism is a paralytic disease caused by the neurotoxin produced by Clostridium botulinum. The majority of cases are due to ingestion or injection drug use. Wound botulism from traumatic injury is exceedingly rare, with only one to two cases reported each year in the United States. CASE REPORT: A 27-year-old man presented to the Emergency Department with diplopia, dysphagia, and progressive weakness 10 days after sustaining a gunshot wound to his right lower leg...
February 12, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29437455/realizing-fulde-ferrell-superfluids-via-a-dark-state-control-of-feshbach-resonances
#4
Lianyi He, Hui Hu, Xia-Ji Liu
We propose that the long-sought Fulde-Ferrell superfluidity with nonzero momentum pairing can be realized in ultracold two-component Fermi gases of ^{40}K or ^{6}Li atoms by optically tuning their magnetic Feshbach resonances via the creation of a closed-channel dark state with a Doppler-shifted Stark effect. In this scheme, two counterpropagating optical fields are applied to couple two molecular states in the closed channel to an excited molecular state, leading to a significant violation of Galilean invariance in the dark-state regime and hence to the possibility of Fulde-Ferrell superfluidity...
January 26, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29414759/proteomic-analysis-of-urothelium-of-rats-with-detrusor-overactivity-induced-by-bladder-outlet-obstruction
#5
Edmond Chankgyun Park, Jae Sung Lim, Seung Il Kim, Sang-Yeop Lee, Yu-Kyung Tak, Chi-Won Choi, Sung-Ho Yun, Joohyun Park, Minji Lee, Hyo Kyun Chung, Koon Soon Kim, Yong Gil Na, Ju Hyun Shin, Gun-Hwa Kim
Overactive bladder (OAB) syndrome is a condition that has four symptoms: urgency, urinary frequency, nocturia, and urge incontinence and negatively affects a patient's life. Recently, it is considered that the urinary bladder urothelium is closely linked to pathogenesis of OAB. However, the mechanisms of pathogenesis of OAB at the molecular level remain poorly understood, mainly as a result of lack of modern molecular analysis. The goal of this study is to identify a potential target protein that could act as a predictive factor for effective diagnosis and aid in the development of therapeutic strategies for the treatment of OAB syndrome...
February 1, 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29409271/comparison-of-postoperative-pain-control-methods-after-bony-surgery-in-the-foot-and-ankle
#6
Chan Kang, Gi-Soo Lee, Sang-Bum Kim, You-Gun Won, Jeong-Kil Lee, You-Sun Jung, Hyung-June Cho
BACKGROUND: We performed a prospective study to evaluate and compare the effectiveness of postoperative pain control methods after bone surgery in the foot and ankle. METHODS: Among the patients who underwent foot and ankle surgery from June 2014 to September 2015 with an ultrasound-guided nerve block, 84 patients who fully completed a postoperative pain survey were enrolled. An opioid patch (fentanyl patch, 25mg) was applied in group A (30 patients). Diluted anesthetic (0...
June 24, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29408776/readability-and-quality-of-wikipedia-pages-on-neurosurgical-topics
#7
Omeed Modiri, Daipayan Guha, Naif M Alotaibi, George M Ibrahim, Nir Lipsman, Aria Fallah
OBJECTIVES: Wikipedia is the largest online encyclopedia with over 40 million articles, and generating 500 million visits per month. The aim of this study is to assess the readability and quality of Wikipedia pages on neurosurgical related topics. PATIENTS AND METHODS: We selected the neurosurgical related Wikipedia pages based on the series of online patient information articles that are published by the American Association of Neurological Surgeons (AANS). We assessed readability of Wikipedia pages using five different readability scales (Flesch Reading Ease, Flesch Kincaid Grade Level, Gunning Fog Index, SMOG) Grade level, and Coleman-Liau Index)...
January 29, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29401226/electron-beam-induced-sterility-and-inhibition-of-ovarian-development-in-the-sakhalin-pine-longicorn-monochamus-saltuarius-coleoptera-cerambycidae
#8
Woo Seong Cho, Hyun-Na Koo, Seung-Hwan Yun, Jae Seon Lee, Dae Hun Jeong, Won Jin Kang, Seung-Ju Lee, Hyun Kyung Kim, Ju-Hwan Han, Young-Dae Kwon, Gun Hyung Kwon, Chul Hak Kim, Gil-Hah Kim
The Sakhalin pine longicorn, Monochamus saltuarius (Gebler; Coleoptera: Cerambycidae), is an insect vector of the pine wilt nematode (PWN), Bursaphelenchus xylophilus (Steiner et Buhrer) Nickle, and is widely distributed in central Korea. M. saltuarius is a forest pest that seriously damages Pinus densiflora (Siebold et Zucc, Pinales: Pinaceae) and Pinus koraiensis (Siebold & Zucc, Pinales: Pinaceae) forests. We examined the effect of electron beam irradiation on the mating, DNA damage and ovarian development of M...
January 30, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29399762/the-effects-of-supraphysiological-estrogen-levels-on-ventricular-repolarization-parameters
#9
Omer Yiginer, Mehmet Dogan, Ismet Gun, Huseyin Tayfun Kutlu, Gokhan Degirmencioglu, İlkin Guliyev, Alptug Tokatli, Fethi Kilicaslan
BACKGROUND: The frequency of arrhythmic death developing without a structural cardiac disease is higher in women. Also female gender is an independent risk factor regarding developing Torsades des Pointes. Several studies have been conducted on the effects of physiological and therapeutic sex hormones on cardiac conduction system. AIM: In this study we aim to examine the effect of hormonal changes occurring during in vitro fertilization treatment and especially supraphysiological E2 levels on ventricular repolarization parameters...
February 5, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29397689/dual-roles-of-graphene-oxide-to-attenuate-inflammation-and-elicit-timely-polarization-of-macrophage-phenotypes-for-cardiac-repair
#10
Jin Han, Yong Sook Kim, Min-Young Lim, Han Young Kim, Saerom Kong, Mikyung Kang, Yeon Woong Choo, Ju Hee Jun, Seungmi Ryu, Hye-Yun Jeong, Jooyeon Park, Gun-Jae Jeong, Jong-Chan Lee, Gwang Hyeon Eom, Youngkeun Ahn, Byung-Soo Kim
Development of localized inflammatory environments by M1 macrophages in the cardiac infarction region exacerbates heart failure after myocardial infarction (MI). Therefore, the regulation of inflammation by M1 macrophages and their timely polarization toward regenerative M2 macrophages suggest an immunotherapy. Particularly, controlling cellular generation of reactive oxygen species (ROS), which cause M1 differentiation, and developing M2 macrophage phenotypes in macrophages propose a therapeutic approach. Previously, stem or dendritic cells were used in MI for their anti-inflammatory and cardioprotective potentials and showed inflammation modulation and M2 macrophage progression for cardiac repair...
February 7, 2018: ACS Nano
https://www.readbyqxmd.com/read/29387861/fabrication-of-dual-stimuli-responsive-multicompartmental-drug-carriers-for-tumor-selective-drug-release
#11
Hyeon Ung Kim, Dae Gun Choi, Hyunjee Lee, Min Suk Shim, Ki Wan Bong
There has been increasing attention to the development of multi-stimuli-responsive drug carriers for precisely controlled drug release at target disease areas. In this study, pH- and redox-responsive hybrid drug carriers were fabricated by using both ketal-based acid-cleavable precursors and disulfide-based reducible precursors via stop-flow lithography. pH- and redox-sensitive drug release of the dual stimuli-responsive hybrid particles was confirmed, demonstrating their feasibility for selective and efficient drug release into tumor tissues in acidic and highly reductive environments...
February 1, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29379117/medial-preoptic-circuit-induces-hunting-like-actions-to-target-objects-and-prey
#12
Sae-Geun Park, Yong-Cheol Jeong, Dae-Gun Kim, Min-Hyung Lee, Anna Shin, Geunhong Park, Jia Ryoo, Jiso Hong, Seohui Bae, Cheol-Hu Kim, Phill-Seung Lee, Daesoo Kim
As animals forage, they must obtain useful targets by orchestrating appropriate actions that range from searching to chasing, biting and carrying. Here, we reveal that neurons positive for the α subunit of Ca2+/calmodulin-dependent kinase II (CaMKIIα) in the medial preoptic area (MPA) that send projections to the ventral periaqueductal gray (vPAG) mediate these target-directed actions in mice. During photostimulation of the MPA-vPAG circuit, mice vigorously engaged with 3D objects and chased moving objects...
January 29, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29362362/ag-migration-effects-on-the-metastable-phase-in-cacu3ti4o12-capacitors
#13
Ji-Won Lee, Gun-Hyun Lee, Dong-Jin Shin, Jinhwan Kim, Soon-Jong Jeong, Jung-Hyuk Koh
The silver migration effect into the metastable phase forms a micro-electric path, to enhance the relative dielectric permittivity of CaCu3Ti4O12 ceramics for electronic devices. Controlling the sintering time uniquely develops the metastable phase of as-sintered CaCu3Ti4O12 ceramics. A post-heating process that applies the migration of silver into the metastable phase increases the relative dielectric permittivity. At 1 kHz frequency, the relative dielectric permittivity at room temperature of the silver-migrated CaCu3Ti4O12 ceramics sintered for 2 h is 565...
January 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29350732/complete-amplitude-and-phase-control-of-light-using-broadband-holographic-metasurfaces
#14
Gun-Yeal Lee, Gwanho Yoon, Seung-Yeol Lee, Hansik Yun, Jaebum Cho, Kyookeun Lee, Hwi Kim, Junsuk Rho, Byoungho Lee
Reconstruction of light profiles with amplitude and phase information, called holography, is an attractive optical technology with various significant applications such as three-dimensional imaging and optical data storage. Subwavelength spatial control of both amplitude and phase of light is an essential requirement for an ideal hologram. However, traditional holographic devices suffer from their restricted capabilities of incomplete modulation in both amplitude and phase of visible light; this results in sacrifice of optical information and undesirable occurrences of critical noises in holographic images...
January 19, 2018: Nanoscale
https://www.readbyqxmd.com/read/29338953/violent-crime-and-park-use-in-low-income-urban-neighborhoods
#15
Bing Han, Deborah A Cohen, Kathryn P Derose, Jiang Li, Stephanie Williamson
INTRODUCTION: Crime and safety are often cited as potential hurdles to park use and park-based physical activity. Using comprehensive data sources including both objective and subjective measurements at the park level and the individual level, this study aimed to assess the association between crime rates and use of local parks in low-income urban neighborhoods. METHODS: The authors observed 48 parks and conducted local resident surveys in low-income neighborhoods in Los Angeles during a 2-year study period (2013-2015)...
January 12, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29336086/learning-to-blast-a-way-into-crime-or-just-good-clean-fun-examining-aggressive-play-with-toy-weapons-and-its-relation-with-crime
#16
Sven Smith, Christopher J Ferguson, Kevin M Beaver
BACKGROUND: Researchers, such as Bandura, have proposed that children's mere exposure to the use of play weapons encourages deviant displays of aggression, but there is very little research to support this hypothesis of 20 years. AIM: To examine the relationship between amount of weapon play and concurrent aggression as well as later violent juvenile crime, while controlling for other variables possibly influencing criminal pathways. METHOD: Using longitudinal survey data collected from mothers and children (n = 2019) from age 5, with follow-up at age 15, correlations between children's play with toy weapons and juvenile criminality were examined...
January 16, 2018: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/29323508/past-focused-temporal-communication-overcomes-conservatives-resistance-to-liberal-political-ideas
#17
Joris Lammers, Matt Baldwin
Nine studies and a meta-analysis test the role of past-focused temporal communication in reducing conservatives' disagreement with liberal political ideas. We propose that conservatives are more prone to warm, affectionate, and nostalgic feelings for past society. Therefore, they are more likely to support political ideas-including those expressing liberal values-that can be linked to a desirable past state (past focus), rather than a desirable future state (future focus) of society. Study 1 supports our prediction that political conservatives are more nostalgic for the past than liberals...
January 11, 2018: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/29304281/transferrable-plasmonic-au-thin-film-containing-sub-20-nm-nanohole-array-constructed-via-high-resolution-polymer-self-assembly-and-nanotransfer-printing
#18
Soonmin Yim, Suwan Jeon, Jong Min Kim, Kwang Min Baek, Gun Ho Lee, Hyowook Kim, Jonghwa Shin, Yeon Sik Jung
The fabrication and characterization of nanoscale hole arrays (NHA) have been extensively performed for a variety of unique characteristics including extraordinary optical transmission phenomenon observed for plasmonic NHAs. Although the size miniaturization and hole densification are strongly required for enhancement of high-frequency optical responses, from a practical point-of-view, it is still not straightforward to manufacture NHA using conventional lithography techniques. Herein, a facile, cost-effective, and transferrable fabrication route for high-resolution and high-density NHA with sub-50 nm periodicity is demonstrated...
January 5, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29282983/sub-nanomolar-sensitivity-of-filter-paper-based-sers-sensor-for-pesticide-detection-by-hydrophobicity-change-of-paper-surface
#19
Minwoo Lee, Kyudeok Oh, Han-Kyu Choi, Sung Gun Lee, Hye Jung Youn, Hak Lae Lee, Dae Hong Jeong
As a cost-effective approach for detecting trace amounts of pesticides, filter paper-based SERS sensors have been the subject of intensive research. One of the hurdles to overcome is the difficulty of retaining nanoparticles on the surface of the paper because of the hydrophilic nature of the cellulose fibers in paper. This reduces the sensitivity and reproducibility of paper-based SERS sensors due to the low density of nanoparticles and short retention time of analytes on the paper surface. In this study, filter paper was treated with alkyl ketene dimer (AKD) to modify its property from hydrophilic to hydrophobic...
December 28, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29281764/interferon-regulatory-factor-1-is-essential-for-pathogenic-cd8-t-cell-migration-and-retention-in-the-brain-during-experimental-cerebral-malaria
#20
Sin Yee Gun, Carla Claser, Teck Hui Teo, Shanshan W Howland, Chek Meng Poh, Rebecca Ren Ying Chye, Lisa F P Ng, Laurent Rénia
Host immune response has a key role in controlling the progression of malaria infection. In the well-established murine model of experimental cerebral malaria (ECM) with P. berghei ANKA infection, pro-inflammatory Th1 and CD8+ T cells response are essential for disease development. Interferon regulatory factor 1 (IRF1) is a transcription factor which promotes Th1 responses and its absence was previously shown to protect from ECM death. Yet, the exact mechanism of protection remains unknown. Here we demonstrated that IRF1-deficient mice (IRF1KO) were protected from ECM death despite displaying early neurological signs...
December 27, 2017: Cellular Microbiology
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