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https://www.readbyqxmd.com/read/29346546/identifying-cardiac-pathologies-with-coronary-wave-intensity-analysis-an-enrichment-to-the-ever-expanding-coronary-haemodynamics-armamentarium
#1
Nico Bruining, Paul Cummins
No abstract text is available yet for this article.
January 16, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29346328/comparison-of-svm-rf-and-elm-on-an-electronic-nose-for-the-intelligent-evaluation-of-paraffin-samples
#2
Hong Men, Songlin Fu, Jialin Yang, Meiqi Cheng, Yan Shi, Jingjing Liu
Paraffin odor intensity is an important quality indicator when a paraffin inspection is performed. Currently, paraffin odor level assessment is mainly dependent on an artificial sensory evaluation. In this paper, we developed a paraffin odor analysis system to classify and grade four kinds of paraffin samples. The original feature set was optimized using Principal Component Analysis (PCA) and Partial Least Squares (PLS). Support Vector Machine (SVM), Random Forest (RF), and Extreme Learning Machine (ELM) were applied to three different feature data sets for classification and level assessment of paraffin...
January 18, 2018: Sensors
https://www.readbyqxmd.com/read/29346107/brain-mr-image-restoration-using-an-automatic-trilateral-filter-with-gpu-based-acceleration
#3
Herng-Hua Chang, Cheng-Yuan Li, Audrey Haihong Gallogly
OBJECTIVE: Noise reduction in brain magnetic resonance (MR) images has been a challenging and demanding task. This study develops a new trilateral filter that aims to achieve robust and efficient image restoration. METHODS: Extended from the bilateral filter, the proposed algorithm contains one additional intensity similarity funct-ion, which compensates for the unique characteristics of noise in brain MR images. An entropy function adaptive to intensity variations is introduced to regulate the contributions of the weighting components...
February 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29346088/intense-olfactory-stimulation-blocks-seizures-in-an-experimental-model-of-epilepsy
#4
Polianna Delfino-Pereira, Poliana Bertti-Dutra, Eduardo Henrique de Lima Umeoka, José Antônio Cortes de Oliveira, Victor Rodrigues Santos, Artur Fernandes, Simone Saldanha Marroni, Flávio Del Vecchio, Norberto Garcia-Cairasco
There are reports of patients whose epileptic seizures are prevented by means of olfactory stimulation. Similar findings were described in animal models of epilepsy, such as the electrical kindling of amygdala, where olfactory stimulation with toluene (TOL) suppressed seizures in most rats, even when the stimuli were 20% above the threshold to evoke seizures in already kindled animals. The Wistar Audiogenic Rat (WAR) strain is a model of tonic-clonic seizures induced by acute acoustic stimulation, although it also expresses limbic seizures when repeated acoustic stimulation occurs - a process known as audiogenic kindling (AK)...
January 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29345757/whole-genome-sequencing-analysis-for-cancer-genomics-and-precision-medicine
#5
REVIEW
Hidewaki Nakagawa, Masashi Fujita
Explosive advances of next-generation sequencer (NGS) and computational analyses have been exploring somatic protein-altered mutations in most cancer types and these coding mutation data are intensively accumulated. However, there is limited information on somatic mutations in non-coding regions including introns, regulatory elements, and non-coding RNAs, structural variants and pathogen in cancer genomes remain widely unexplored. Whole genome sequencing (WGS) approaches can comprehensively explore all types of genomic alterations in cancer and help us to better understand the whole landscape of driver mutations and mutational signature in cancer genomes and elucidate functional or clinical implications of these unexplored genomic regions and mutational signature...
January 18, 2018: Cancer Science
https://www.readbyqxmd.com/read/29345547/are-current-physical-match-performance-metrics-in-elite-soccer-fit-for-purpose-or-is-the-adoption-of-an-integrated-approach-needed
#6
Paul S Bradley, Jack D Ade
Time-motion analysis is a valuable data-collection technique used to quantify the physical match performance of elite soccer players. For over 40 years researchers have adopted a 'traditional' approach when evaluating match demands by simply reporting the distance covered or time spent along a motion continuum of walking through to sprinting. This methodology quantifies physical metrics in isolation without integrating other factors and this ultimately leads to a one-dimensional insight into match performance...
January 18, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29345506/effects-of-physical-and-depressive-symptoms-on-the-sexual-life-of-turkish-women-in-the-climacteric-period
#7
E Yanikkerem, A Göker, Ö Çakır, N Esmeray
OBJECTIVE: To assess the effects of physical and depressive symptoms on the sexual life of women in the climacteric period. METHODS: This study was conducted with 572 women at a university hospital. The Beck Depression Inventory (BDI), Menopause Rating Scale (MRS) and Female Sexual Function Index (FSFI) were used to evaluate depressive symptoms, intensity of menopausal symptoms and sexual function. RESULTS: Sexual dysfunction and depressive symptoms were determined in 86...
January 18, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29345146/quantitative-contrast-enhanced-ultrasound-for-monitoring-vedolizumab-therapy-in-inflammatory-bowel-disease-patients-a-pilot-study
#8
Ruediger S Goertz, Daniel Klett, Dane Wildner, Raja Atreya, Markus F Neurath, Deike Strobel
Background Microvascularization of the bowel wall can be visualized and quantified non-invasively by software-assisted analysis of derived time-intensity curves. Purpose To perform software-based quantification of bowel wall perfusion using quantitative contrast-enhanced ultrasound (CEUS) according to clinical response in patients with inflammatory bowel disease treated with vedolizumab. Material and Methods In a prospective study, in 18 out of 34 patients, high-frequency ultrasound of bowel wall thickness using color Doppler flow combined with CEUS was performed at baseline and after 14 weeks of treatment with vedolizumab...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29345109/effectiveness-of-smartphone-technologies-on-glycaemic-control-in-patients-with-type-2-diabetes-systematic-review-with-meta-analysis-of-17-trials
#9
REVIEW
I X Y Wu, J C Y Kee, D E Threapleton, R Ma, V C K Lam, E K P Lee, S Y S Wong, V C H Chung
Patient education and behavioural interventions for self-management of type 2 diabetes mellitus (T2DM) are effective but place demands on manpower resources. This systematic review aimed to investigate the effectiveness of smartphone technologies (STs) for improving glycaemic control among T2DM patients. CENTRAL, MEDLINE, Embase, CINAHL and ScienceDirect were searched through December 2016. Randomized controlled trials comparing STs with usual diabetes care among T2DM patients and reporting change in glycated haemoglobin (HbA1c) level were included...
January 17, 2018: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29345071/detecting-selection-signatures-on-the-x-chromosome-of-the-chinese-debao-pony
#10
X-X Liu, J-F Pan, Q-J Zhao, X-H He, Y-B Pu, J-L Han, Y-H Ma, L Jiang
The X chromosome shows a special interaction between demographic factors and genetic variation, and the analysis of X-linked genomic variation can therefore provide insights into the unique effects of demography and selection on the horse genome that cannot be readily detected by autosomal markers. Debao (DB) ponies have experienced intense selective pressure for the development of their small stature (<106 cm at adult height). To identify selective sweeps on the X chromosome of the DB pony, we performed a genome-wide scan of three Chinese horse breeds using an Equine SNP70 BeadChip...
February 2018: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/29344887/phosphoproteomics-based-profiling-of-kinase-activities-in-cancer-cells
#11
Jakob Wirbel, Pedro Cutillas, Julio Saez-Rodriguez
Cellular signaling, predominantly mediated by phosphorylation through protein kinases, is found to be deregulated in most cancers. Accordingly, protein kinases have been subject to intense investigations in cancer research, to understand their role in oncogenesis and to discover new therapeutic targets. Despite great advances, an understanding of kinase dysfunction in cancer is far from complete.A powerful tool to investigate phosphorylation is mass-spectrometry (MS)-based phosphoproteomics, which enables the identification of thousands of phosphorylated peptides in a single experiment...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344743/response-to-different-furosemide-doses-predicts-aki-progression-in-icu-patients-with-elevated-plasma-ngal-levels
#12
Ryo Matsuura, Yohei Komaru, Yoshihisa Miyamoto, Teruhiko Yoshida, Kohei Yoshimoto, Rei Isshiki, Kengo Mayumi, Tetsushi Yamashita, Yoshifumi Hamasaki, Masaomi Nangaku, Eisei Noiri, Naoto Morimura, Kent Doi
BACKGROUND: Furosemide responsiveness (FR) is determined by urine output after furosemide administration and has recently been evaluated as a furosemide stress test (FST) for predicting severe acute kidney injury (AKI) progression. Although a standardized furosemide dose is required for FST, variable dosing is typically employed based on illness severity, including renal dysfunction in the clinical setting. This study aimed to evaluate whether FR with different furosemide doses can predict AKI progression...
January 17, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29344398/exploring-nurse-managers-perception-of-using-the-rafaela-system-as-a-management-tool-in-a-norwegian-hospital-setting
#13
Bodil Mørk Lillehol, Kjersti Lønning, Marit Helen Andersen
Aim: The aim of the study, being part of a Norwegian evaluation project of the RAFAELA system, was to explore nurse managers' perception of the RAFAELA system as a management tool in a Norwegian hospital setting. Design: We applied an explorative qualitative design using focus group interviews. Methods: Two focus group interviews were performed with 12 nurses in different management positions during autumn 2013. The principles of qualitative content analysis were used for analysing data...
January 2018: Nursing Open
https://www.readbyqxmd.com/read/29344389/family-members-satisfaction-with-care-and-decision-making-in%C3%A2-intensive-care-units-and-post-stay-follow-up-needs-a-cross-sectional-survey-study
#14
Gro Frivold, Åshild Slettebø, Daren K Heyland, Bjørg Dale
Aim: The aim of this study was to explore family members' satisfaction with care and decision-making during the intensive care units stay and their follow-up needs after the patient's discharge or death. Design: A cross-sectional survey study was conducted. Methods: Family members of patients recently treated in an ICU were participating. The questionnaire contented of background variables, the instrument Family Satisfaction in ICU (FS-ICU 24) and questions about follow-up needs...
January 2018: Nursing Open
https://www.readbyqxmd.com/read/29344243/t-cell-immunoglobulin-and-mucin-domain-containing-protein-3-and-galectin-9-protein-expression-potential-prognostic-significance-in-esophageal-squamous-cell-carcinoma-for-chinese-patients
#15
Nan Hou, Jie Ma, Wei Li, Lingdi Zhao, Quanli Gao, Ling Mai
The aim of the present study was to investigate the expression levels of the T-cell immunoglobulin and mucin domain-containing protein-3 (TIM-3) and galectin-9 proteins and their clinical value in esophageal squamous cell carcinoma (ESCC) in Chinese patients. The expression profiles of TIM-3 and galectin-9 in ESCC were determined by the immunohistochemical analysis of the postoperative pathological specimens of 45 patients with ESCC; a χ2 test was used to evaluate the association of TIM-3 and galectin-9 expression with clinicopathological parameters, in addition to univariate and multivariate Cox's proportional hazards model to analyze the prognostic value of the expression of TIM-3 and galectin-9 proteins...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344223/application-of-intensity-modulated-radiation-therapy-in-the-treatment-of-nasopharyngeal-carcinoma
#16
Hao Yan, Xiaoming Cao, Jinmei Wang
The objective of the present study was to investigate the application values of the intensity-modulated radiation therapy (IMRT) and the three-dimensional conformal radiation therapy (3D-CRT) in the treatment of nasopharyngeal carcinoma (NPC). A total of 124 patients diagnosed with nasopharyngeal carcinomas were included into the study and randomly divided into the control group and the observation group, with 62 patients in each group. The 3D-CRT combined with postoperative chemotherapy were performed on the control group and the observation group received IMRT combined with postoperative chemotherapy, and then were followed up for a median duration of 25...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344199/expression-and-prognostic-significance-of-doublecortin-like-kinase-1-in-patients-with-hepatocellular-carcinoma
#17
Mengjiao Fan, Niansong Qian, Guanghai Dai
Doublecortin-like kinase 1 (DCLK1), a putative cancer stem cell marker in intestinal and pancreatic tumors, is associated with tumor pathogenesis and progression, and poor survival outcomes in numerous types of cancer. However, DCLK1 expression and its prognostic value remain unclear in hepatocellular carcinoma (HCC). In the present study, the expression of DCLK1 was assessed using immunohistochemistry in 96 resected HCC and 68 adjacent tissue specimens. The staining intensity and the percentage of stained cells were scored on a scale of 0-3 and 0-4, respectively...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344136/clinical-outcome-of-extended-field-irradiation-vs-pelvic-irradiation-using-intensity-modulated-radiotherapy-for-cervical-cancer
#18
Yi Ouyang, Yanhong Wang, Kai Chen, Xinping Cao, Yiming Zeng
The aim of the present study was to evaluate the distinctions in survival and toxicity between patients with cervical cancer with common iliac node or para-aortic node involvement, who were treated with extended-field intensity-modulated radiotherapy (EF-IMRT) and patients with or without lower involved pelvic nodes, who were treated with pelvic IMRT. A total of 55 patients treated with EF-IMRT and 52 patients treated with pelvic IMRT at the Sun Yat-Sen University Cancer Center (Guangzhou, China) were retrospectively analyzed...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344051/experiences-of-fathers-with-inpatient-premature-neonates-phenomenological-interpretative-analysis
#19
Tahmineh Dadkhahtehrani, Narges Eskandari, Zohre Khalajinia, Hoda Ahmari-Tehran
Background: Birth and hospitalization of premature neonates create enormous challenges for the family with serious impacts on parents' mental and emotional health. The present study was designed to explore the experiences of fathers with premature neonates hospitalized in a neonatal intensive care unit (NICU). Materials and Methods: In this interpretative phenomenological study, data were collected using in-depth interviews guided with a semi-structured questionnaire and analyzed by interpretative phenomenological analysis...
January 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29344048/the-impact-of-normal-saline-on-the-incidence-of-exposure-keratopathy-in-patients-hospitalized-in-intensive-care-units
#20
Zohreh Davoodabady, Korosh Rezaei, Reza Rezaei
Background: Patients in the intensive care unit (ICU) have impaired ocular protective mechanisms that lead to an increased risk of ocular surface diseases including exposure keratopathy (EK). This study was designed to evaluate the effect of normal saline (NS) on the incidence and severity of EK in critically ill patients. Materials and Methods: This single-blind randomized controlled trial was conducted on 50 patients admitted to ICUs. The participants were selected through purposive sampling...
January 2018: Iranian Journal of Nursing and Midwifery Research
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