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https://www.readbyqxmd.com/read/29149122/leukostasis-management-to-prevent-crisis-in-acute-leukemia%C3%A2
#1
Lisa M Blackburn, Shelly Brown, Aimee Munyon, Michelle Orovets
BACKGROUND: Hyperleukocytosis, a peripheral white blood cell count greater than 100,000/mm3,is most commonly seen in patients with newly diagnosed or relapsed acute lymphoblastic leukemia and acute myeloid leukemia. Leukostasis is a reduction in blood flow related to hyperviscosity. Hyperleukocytosis, causing leukostasis, is an oncologic emergency and requires an exacting assessment and rapid response with appropriate intervention to prevent morbidity and mortality in the first week after diagnosis...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29127912/pesticides-contaminated-dust-exposure-risk-diagnosis-and-exposure-markers-in-occupational-and-residential-settings-of-lahore-pakistan
#2
Sidra Waheed, Crispin Halsall, Andrew J Sweetman, Kevin C Jones, Riffat Naseem Malik
There are few studies documenting the dust loaded with pesticides as a potential non-dietary exposure source for occupational worker and populations living near agricultural farms and pesticides formulation plants. In present study we have evaluated the pesticide concentration in dust from potential sites and relevant health risk from dust ingestion. Furthermore, the effect of currently used pesticides was investigated on blood and urine parameters of subjects: farmer, factory worker, urban resident and rural resident and controlled subjects with presumably different levels of exposure...
November 7, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29118150/gastroesophageal-reflux-disease-symptom-screening-in-a-dental-setting
#3
Anisha Raibrown, Lori J Giblin, Linda D Boyd, Kristen Perry
Purpose: Gastroesophageal Reflux Disease (GERD) is a chronic health condition in which the symptoms often go unnoticed. Oral problems accompanying GERD may include non-specific burning sensation, mucosa ulceration and erosion, erythema of the soft/hard palate mucosa and uvula, loss of taste and either xerostomia or increased salivary flow with potential long-term complications such as difficulty swallowing, trouble breathing, esophagitis and potential development of esophageal adenocarcinoma (EAC). The purpose of this study was to assess the feasibility of using a GERD screening in the dental clinic setting to identify and refer patients...
February 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29111542/a-call-to-action-to-develop-integrated-curricula-in-cardiorenal-medicine
#4
Claudio Ronco, Federico Ronco, Peter A McCullough
With the adoption of the new definition and classification of cardiorenal syndrome (CRS) and its relevant subtypes, much attention has been placed on elucidating the mechanisms of heart and kidney interactions. The pathophysiologic pathways are of great interest by which acute heart failure may result in acute kidney injury (AKI; type 1), chronic heart failure accelerates the progression of chronic kidney disease (CKD; type 2), AKI provokes cardiac events (type 3), and CKD increases the risk and severity of cardiovascular disease (type 4)...
2017: Reviews in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29110206/incorporating-islamic-creed-into-islamic-counselling-process-a-guideline-to-counsellors
#5
Norazlina Zakaria, Noor Shakirah Mat Akhir
This article is a concept paper that reviewed the main principles of Islamic creed (aqīdah) related to counselling. Islamic creed has been regarded as the root of Islam; thus, it should be the fundamental composition of Islamic counselling. The objectives of this review are to demonstrate the relationship between counselling and Islamic creed and to establish a guideline for the practitioners of Islamic counselling when consulting with their clients in matters related to creed. The review was conducted by suggesting methods to incorporate Islamic creed into three stages of counselling process...
November 7, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/29110204/shiite-perspective-on-the-moral-status-of-the-early-human-embryo-a-critical-review
#6
Kiarash Aramesh
According to Shiite perspective, the relative inviolability of the human embryo starts at the time of implantation and attains complete ethical status at ensoulment. Different paradigms of embryology have been influential on the understanding of Shiite jurists of the relevant Qur'anic verses. This paper provides a critical review of the process of issuing religious decrees on issues related to the early human life and concludes that Shiite jurisprudence needs to obtain consistency in its adopted account of embryology and adopt a proactive approach toward the bioethical new-emerging issues...
November 6, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/29107303/physiology-of-pain
#7
REVIEW
Deborah L Ellison
Acutely ill patients are challenging to frontline nurses because they frequently also have multiple chronic conditions. This article empowers all nurses to develop a foundational understanding of the physiology of acute and chronic pain. The skills, knowledge, and attitude to care for patients experiencing pain are a legal and ethical responsibility of all nurses. This article discusses the physiology of pain to include the neuronal receptors that respond to various painful stimuli, substances that stimulate nociceptors, the nerve pathways, modulation of the perception of pain, and acute verses chronic physiologic changes...
December 2017: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29103352/cyberbullying-and-social-media-information-and-interventions-for-school-nurses-working-with-victims-students-and-families
#8
Elizabeth Byrne, Judith A Vessey, Lauren Pfeifer
Social media has become an increasingly prevalent fixture in youths' lives, with over 90% of teenagers reporting daily usage. These online sites and applications have provided many positive opportunities for youths to connect and share ideas with others; however, social media has also become a major platform for cyberbullying. Victims often experience negative health outcomes directly related to cyberbullying. For this reason, it is critical that third parties, such as school nurses, are well versed in social media and the warning signs of those being victimized by cyberbullying...
January 1, 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/29094944/design-of-mc1r-selective-%C3%AE-msh-analogues-with-canonical-amino-acids-leads-to-potency-and-pigmentation
#9
Yang Zhou, Saghar Mowlazadeh Haghighi, Ioanna Zoi, Jonathon R Sawyer, Victor J Hruby, Minying Cai
Melanoma is a lethal form of skin cancer. Skin pigmentation, which is regulated by the melanocortin 1 receptor (MC1R), is an effective protection against melanoma. However, the endogenous MC1R agonists lack selectivity for the MC1R and thus can have side effects. The use of noncanonical amino acids in previous MC1R ligand development raises safety concerns. Here we report the development of the first potent and selective hMC1R agonist with only canonical amino acids. Using γ-MSH as a template, we developed a peptide, [Leu(3), Leu(7), Phe(8)]-γ-MSH-NH2 (compound 5), which is 16-fold selective for the hMC1R (EC50 = 4...
November 13, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29089725/evidence-for-idarucizumab-praxbind-in-the-reversal-of-the-direct-thrombin-inhibitor-dabigatran-review-following-the-re-verse-ad-full-cohort-analysis
#10
Timothy C Hutcherson, Nicole E Cieri-Hutcherson, Rajvi Bhatt
Idarucizumab is the first reversal agent approved for the direct thrombin inhibitor dabigatran. The authors summarize the findings from the clinical trial series and describe case reports, post-marketing data, and ongoing studies.
November 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29078931/oncologic-metabolic-emergencies
#11
REVIEW
Jonathan Wagner, Sanjay Arora
Cancer and its therapies may lead to several metabolic emergencies that emergency providers (EPs) should be well-versed in identifying and managing. With prompt recognition and treatment initiation in the emergency department, lives can be saved and quality of life maintained. Most oncologic metabolic emergencies occur in advanced cancer states, but some follow initiation of treatment or may be the presenting syndrome that leads to the cancer diagnosis. This article reviews the 2 most emergent oncologic metabolic diagnoses: tumor lysis syndrome and hypercalcemia of malignancy...
December 2017: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29078649/prevention-and-management-of-intraoperative-crisis-in-vats-and-open-chest-surgery-how-to-avoid-emergency-conversion
#12
REVIEW
Fernando M Safdie, Manuel Villa Sanchez, Inderpal S Sarkaria
Video assisted thoracic surgery (VATS) has become a routinely utilized approach to complex procedures of the chest, such as pulmonary resection. It has been associated with decreased postoperative pain, shorter length of stay and lower incidence of complications such as pneumonia. Limitations to this modality may include limited exposure, lack of tactile feedback, and a two-dimensional view of the surgical field. Furthermore, the lack of an open incision may incur technical challenges in preventing and controlling operative misadventures leading to major hemorrhage or other intraoperative emergencies...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29076731/calorimetric-study-of-the-activation-of-hydrogen-by-tris-pentafluorophenyl-borane-and-trimesitylphosphine
#13
Adrian Y Houghton, Tom Autrey
The mechanism of H2 heterolysis by the frustrated Lewis pair of B(C6F5)3 and P(mes)3 was investigated by isothermal reaction calorimetry in the temperature range from 30 to 90 °C. The experimental heat curves were modeled in Berkeley Madonna to obtain both kinetic and thermodynamics data simultaneously. The H2 activation reaction is treated as a single, termolecular step with a rate constant of 0.61 M(-2) s(-1) at 303 K with an exothermic enthalpy of reaction, ΔHH2 = -141 kJ/mol. An Eyring analysis gave activation parameters of ΔH(‡) = 13...
November 9, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29065398/a-call-to-action-to-develop-integrated-curricula-in-cardiorenal-medicine
#14
Claudio Ronco, Federico Ronco, Peter A McCullough
With the adoption of the new definition and classification of cardiorenal syndrome (CRS) and its relevant subtypes, much attention has been placed on elucidating the mechanisms of heart and kidney interactions. Of great interest are the pathophysiological pathways by which acute heart failure may result in acute kidney injury (AKI; type 1), chronic heart failure accelerating the progression of chronic kidney disease (CKD; type 2), AKI provoking cardiac events (type 3), and CKD increasing the risk and severity of cardiovascular disease (type 4)...
October 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/29059115/using-lean-process-improvement-to-enhance-safety-and-value-in-orthopaedic-surgery-the-case-of-spine-surgery
#15
Rajiv Sethi, Vijay Yanamadala, Douglas C Burton, Robert Shay Bess
Lean methodology was developed in the manufacturing industry to increase output and decrease costs. These labor organization methods have become the mainstay of major manufacturing companies worldwide. Lean methods involve continuous process improvement through the systematic elimination of waste, prevention of mistakes, and empowerment of workers to make changes. Because of the profit and productivity gains made in the manufacturing arena using lean methods, several healthcare organizations have adopted lean methodologies for patient care...
November 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29058603/incorporating-religion-and-spirituality-into-the-design-of-community-based-physical-activity-programs-for-african-american-women-a-qualitative-inquiry
#16
Rodney P Joseph, Barbara E Ainsworth, LaTanya Mathis, Steven P Hooker, Colleen Keller
OBJECTIVE: Limited research has examined how aspects of religion and spirituality can be incorporated into community-based physical activity programs delivered outside of religious institutions. The purpose of this study was to qualitatively explore how spirituality and religion can be leveraged in the design of community-based physical activity programs for African American women delivered outside of faith-based or faith-placed settings. RESULTS: Three focus groups were conducted were conducted with 23 African American women (M age = 37...
October 23, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29056090/seasonal-differences-in-light-exposure-and-the-associations-with-health-and-well-being-in-older-adults-an-exploratory-study
#17
Amanda Nioi, Jenny Roe, Alan Gow, David McNair, Peter Aspinall
OBJECTIVE: This article reports summer verses winter seasonal variations across a suite of blue light, illuminance levels and health and well-being indicators. BACKGROUND: The quality of lighting in care homes has been assessed previously, yet seasonal comparisons and the associations with sleep quality are limited. This exploratory study investigates light exposure in two seasons to determine the changes over time and the associations with health and well-being...
October 2017: HERD
https://www.readbyqxmd.com/read/29044332/obesity-the-verse-and-the-reverse
#18
EDITORIAL
Dirceu Reis da Silva
No abstract text is available yet for this article.
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29032802/radioembolisation-of-hepatocellular-carcinoma-a-primer
#19
REVIEW
N Venkatanarasimha, A Gogna, K T A Tong, K Damodharan, P K H Chow, R H G Lo, S Chandramohan
Transarterial radioembolisation (TARE) has gained increasing acceptance as an additional/alternative locoregional treatment option for hepatocellular carcinoma, and colorectal hepatic metastases that present beyond potentially curative options. This is a catheter-based transarterial selective internal brachytherapy that involves injection of radioactive microspheres (usually Y-90) that are delivered selectively to the liver tumours. Owing to the combined radioactive and microembolic effect, the findings at follow-up imaging are significantly different from that seen with other transarterial treatment options...
October 9, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29032111/paranormal-belief-and-errors-of-probabilistic-reasoning-the-role-of-constituent-conditional-relatedness-in-believers-susceptibility-to-the-conjunction-fallacy
#20
Paul Rogers, John E Fisk, Emma Lowrie
The present study examines the extent to which stronger belief in either extrasensory perception, psychokinesis or life-after-death is associated with a proneness to making conjunction errors (CEs). One hundred and sixty members of the UK public read eight hypothetical scenarios and for each estimated the likelihood that two constituent events alone plus their conjunction would occur. The impact of paranormal belief plus constituents' conditional relatedness type, estimates of the subjectively less likely and more likely constituents plus relevant interaction terms tested via three Generalized Linear Mixed Models...
October 12, 2017: Consciousness and Cognition
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