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https://www.readbyqxmd.com/read/28917372/transcendental-meditation-for-lowering-blood-pressure-an-overview-of-systematic-reviews-and-meta-analyses
#1
REVIEW
Soo Liang Ooi, Melisa Giovino, Sok Cheon Pak
BACKGROUND: Transcendental meditation (TM) is a stress reduction technique that can potentially lower blood pressure (BP) safely. The American Heart Association recommends that TM may be considered in clinical practice. OBJECTIVE: To provide an overview of all systematic reviews and meta-analyses of TM on BP for evidence-informed clinical decision making. METHOD: Systematic searches of PubMed, EBSCOhost, Cochrane Library, Web of Science, Embase, and PsycINFO for all systematic reviews and/or meta-analyses of randomized controlled trials (RCTs) with TM as an intervention, and outcome measures include systolic BP (SBP) and diastolic BP (DBP)...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28903573/crispr-in-research-and-treatment-of-multiple-myeloma
#2
M M Simicek, K Growkova, R Hájek
In the recent years, there was a remarkable advance in research and clinical implementation of the genome editing technologies. The most remarkable was a discovery of the bacterial adaptive immune system called CRISPR and its rapid transformation into a robust and broadly applicable technology that completely revolutionized both basic and applied biomedical research. Implementation of CRISPR makes genome modification easier, faster and significantly cheaper compare to any other currently available technology...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28901019/isolation-and-characterization-of-pathogenic-vibrio-alginolyticus-from-sea-cage-cultured-cobia-rachycentron-canadum-linnaeus-1766-%C3%A2-in-india
#3
P Rameshkumar, A K A Nazar, M A Pradeep, C Kalidas, R Jayakumar, G Tamilmani, M Sakthivel, A K Samal, S Sirajudeen, V Venkatesan, B M Nazeera
Mass mortalities of cobia Rachycentron canadum sub-adults occurred during August 2013 in cage culture at the Gulf of Mannar, Mandapam Tamil Nadu, India. The epizootic of disease was started with typical classical clinical signs followed by the acute mortality. Grossly, severe haemorrhage and congestion was observed in the gastric mucosa. Abdomen was distended with peritoneal fluid. Heart revealed haemopericardium and fibrinous pericardium. Histologically, the gastric mucosa showed severe erosion and necrosis...
September 12, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28894946/an-international-survey-on-non-invasive-techniques-to-assess-the-microcirculation-in-patients-with-raynaud-s-phenomenon-sunshine-survey
#4
Francesca Ingegnoli, Nicola Ughi, Graham Dinsdale, Annalisa Orenti, Patrizia Boracchi, Yannick Allanore, Ivan Foeldvari, Alberto Sulli, Maurizio Cutolo, Vanessa Smith, Ariane L Herrick
To canvas opinion concerning the role of non-invasive techniques in the assessment of patients with Raynaud's phenomenon (Rp) in clinical and research settings: four nailfold capillaroscopy methods [videocapillaroscopy (NVC), dermoscopy, stereomicroscopy, digital USB microscopy], four laser Doppler methods (laser Doppler flowmetry, imaging, anemometry/velocimetry, laser speckle contrast analysis), thermographic imaging, and upper limb arterial Doppler ultrasound. Emails with a link to the survey were sent to physicians from the European Scleroderma Trials and Research group (EUSTAR), the EULAR Study Group on Microcirculation in Rheumatic Diseases (SG_MC/RD) and members of the pediatric rheumatology Email board...
September 11, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28891358/defensive-medicine-among-obstetricians-and-gynaecologists-in-turkey
#5
Mert Küçük
In recent years, there has been a remarkable increase in medical malpractice litigations against OB/GYNs in Turkey and globally. This high litigation atmosphere may have changed attitudes, behaviour and practice of OB/GYNs. In the current study, opinions and attitudes of OB/GYNs regarding defensive medicine and to what extent they practice it were investigated. One hundred and eight OB/GYNs participated in the study. All participants found obstetrics and gynaecology riskier when compared with other medical branches and reported that they were increasingly practising defensive medicine...
September 11, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28876680/registrar-perceptions-on-general-surgical-training-in-south-africa-a-report-by-the-south-african-society-of-surgeons-in-training-sassit
#6
N Patel, A Leusink, N Singh, M Z Koto, T Luvhengo
BACKGROUND: Surgical training varies significantly even amongst universities within the same country. This trend is reflected in South Africa and provides an opportunity for innovation to improve the quality of general surgical training. METHOD: A prospective descriptive study was performed by means of a confidential questionnaire distributed to general surgical registrars at all 8 training centres in South Africa. Participants were asked to give comments regarding adequacy of formal academic teaching, level of supervision during surgical procedures, exposure to and training in minimally invasive surgery (MIS), and preparation for examinations...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28874243/central-regional-anaesthesia-in-patients-with-aortic-stenosis-a-systematic-review
#7
Sofia Johansson, Morten Nikolaj Lind
INTRODUCTION: Aortic stenosis is a valvular lesion that poses several haemodynamic challenges for the anaesthesiologist. The use of central regional anaesthesia is traditionally regarded as contraindicated in patients with severe aortic stenosis due to its sympatholytic effect, potentially causing loss of vascular tone and ultimately diminished cardiac output. The aim of this paper was to review current literature to find evidence for or against the use of neuroaxial blockade in patients with aortic stenosis...
September 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28865591/diagnostics-in-tarsal-fusion-the-theory-and-practise-in-the-netherlands
#8
Mark Stegeman, Berbke T J van Ginneken, Marc G Romijn, René M Castelein, Jan Willem K Louwerens
BACKGROUND: This study compares the preferences of Dutch orthopaedic surgeons for different diagnostic modalities in performing tarsal fusions versus consensus, evidence or expert opinion reported in the literature. METHODS: A literature search of Medline was performed to obtain evidence-based information on various diagnostic tools. In addition, 89 registered Dutch foot and ankle surgeons were sent a questionnaire concerning the diagnostic modalities use in tarsal fusion...
September 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28861167/can-rheumatoid-arthritis-ever-cease-to-exist-a-review-of-various-therapeutic-modalities-to-maintain-drug-free-remission
#9
Di Liu, Na Yuan, Guimei Yu, Ge Song, Yan Chen
Therapies for rheumatoid arthritis (RA) were mostly aimed at reducing the pain, stiffness and further progression of joint destruction. However, with the advent of biologic agents that act against specific inflammatory cytokines contributing to RA pathogenesis (treat-to-target strategy), the degree of remission achieved has been remarkably impressive. In particular, inhibition of tumor necrosis factor α (TNFα), interleukins-1 and -6 and receptor-activator of nuclear kappa B ligand by neutralizing antibodies in early diagnosed RA patients has resulted in lowering of disease activity to levels that enable them to function as in the pre-disease stage...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28846458/effects-of-regular-exercise-on-asthma-control-in-young-adults
#10
Sirpa A M Heikkinen, Elina M S Mäkikyrö, Timo T Hugg, Maritta S Jaakkola, Jouni J K Jaakkola
BACKGROUND: According to our systematic literature review, no previous study has assessed potential effects of regular exercise on asthma control among young adults. We hypothesized that regular exercise improves asthma control among young adults. METHODS: We studied 162 subjects with current asthma recruited from a population-based cohort study of 1623 young adults 20-27 years of age. Asthma control was assessed by the occurrence of asthma-related symptoms, including wheezing, shortness of breath, cough, and phlegm production, during the past 12 months...
August 28, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28844171/a-clinical-decision-making-algorithm-for-penicillin-allergy
#11
Angèle Soria, Elodie Autegarden, Emmanuelle Amsler, Hafida Gaouar, Amandine Vial, Camille Francès, Jean-Eric Autegarden
BACKGROUND: About 10% of subjects report suspected penicillin allergy, but 85-90% of these patients are not truly allergic and could safely receive beta-lactam antibiotics Objective: To design and validate a clinical decision-making algorithm, based on anamnesis (chronology, severity, and duration of the suspected allergic reactions) and reaching a 100% sensitivity and negative predictive value, to assess allergy risk related to a penicillin prescription in general practise. STUDY DESIGN AND METHODS: All patients were included prospectively and explorated based on ENDA/EAACI recommendations...
August 26, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28829187/mass-killing-under-the-guise-of-ect-the-darkest-chapter-in-the-history-of-biological-psychiatry
#12
G Gazdag, G S Ungvari, H Czech
Following its inception, electroconvulsive therapy (ECT), rapidly spread all over the world, including Nazi Germany. Paradoxically, at the same time, the euthanasia programme was started in Germany: the extermination of people with intellectual disabilities and severe psychiatric disorders. In Lower Austria, Dr Emil Gelny, who had been granted a specialist qualification in psychiatry after three months of clinical training, took control of two psychiatric hospitals, in Gugging and Mauer-Öhling. In 1944, he began systematically killing patients with an ECT machine, something that was not practised anywhere else before or after, and remains unprecedented in the history of convulsive therapy...
August 1, 2017: History of Psychiatry
https://www.readbyqxmd.com/read/28827877/occupational-therapy-in-india-focus-on-functional-recovery-and-need-for-empowerment
#13
Reema Samuel, K S Jacob
While there have been significant advances in treatments for mental disorders over the past century, cure for many mental disorders remains elusive. The complex problems of mental illness require a multi-sectoral, multi-disciplinary and multi-dimensional approach to care. The need for focus on biopsychosocial model rather than on biomedical practise, client-centred rather than physician-oriented care, personal rather than clinical recovery, are often preached but rarely practiced. The lack of emphasis on functioning and the limited workforce and evidence base complicate issues related to the care of people with chronic mental illness in India...
April 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28814268/the-genomic-architecture-of-mastitis-resistance-in-dairy-sheep
#14
G Banos, G Bramis, S J Bush, E L Clark, M E B McCulloch, J Smith, G Schulze, G Arsenos, D A Hume, A Psifidi
BACKGROUND: Mastitis is the most prevalent disease in dairy sheep with major economic, hygienic and welfare implications. The disease persists in all dairy sheep production systems despite the implementation of improved management practises. Selective breeding for enhanced mastitis resistance may provide the means to further control the disease. In the present study, we investigated the genetic architecture of four mastitis traits in dairy sheep. Individual animal records for clinical mastitis occurrence and three mastitis indicator traits (milk somatic cell count, total viable bacterial count in milk and the California mastitis test) were collected monthly throughout lactation for 609 ewes of the Greek Chios breed...
August 16, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28814216/opting-for-rural-practice-the-influence-of-medical-student-origin-intention-and-immersion-experience
#15
Denese Playford, Hanh Ngo, Surabhi Gupta, Ian B Puddey
OBJECTIVE: To compare the influence of rural background, rural intent at medical school entry, and Rural Clinical School (RCS) participation on the likelihood of later participation in rural practice. DESIGN: Analysis of linked data from the Medical School Outcomes Database Commencing Medical Students Questionnaire (CMSQ), routinely collected demographic information, and the Australian Health Practitioner Regulation Agency database on practice location. SETTING AND PARTICIPANTS: University of Western Australia medical students who completed the CMSQ during 2006-2010 and were practising medicine in 2016...
August 21, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28810351/-schofield-and-the-first-spread-of-western-medicine-in-shanxi
#16
J Y Zheng
After the Second Opium War, the signing of the Tientsin Treaty and the Peking Treaty legitimized the missionary activities and authorized the missionary the rights to enter inland China for propagating their religious doctrines. In the late 1870s, the"The extraordinary famine of the Ding Wu year"and the subsequent epidemic provided the opportunity for missionaries to enter Shanxi. Dr. Schofield, sent by the China Inland Mission, arrived in Taiyuan in 1880, set up clinics and practised there. He died of typhus after treating a typhus patient in the summer of 1883...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28809084/practice-characteristics-and-service-provision-rates-of-dental-hygienists-in-australia
#17
N Amarasena, D N Teusner, D S Brennan, J Satur
INTRODUCTION: Dental hygienists (DHs) have been practising in Australia since the early 1970s. OBJECTIVE: This study describes the clinical activity of Australian DHs. METHODS: A questionnaire was mailed to members of two professional associations representing DHs. Practitioner characteristics, employment characteristics and clinical activity on a self-reported typical practice day were collected. The proportion of each service item of all services provided was estimated...
August 14, 2017: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/28807974/exploring-family-physicians-reasons-to-continue-or-discontinue-providing-intrapartum-care-qualitative-descriptive-study
#18
Marion Dove, Maman Joyce Dogba, Charo Rodríguez
OBJECTIVE: To examine the reasons why family physicians continue or discontinue providing intrapartum care in their clinical practice. DESIGN: Qualitative descriptive study. SETTING: Two hospitals located in a multicultural area of Montreal, Que, in November 2011 to June 2012. PARTICIPANTS: Sixteen family physicians who were current or former providers of obstetric care. METHODS: Data were collected using semistructured qualitative interviews...
August 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28799281/cultivating-a-culture-of-research-in-nursing-through-a-journal-club-for-leaders-a-pilot-study
#19
Mette Kjerholt, Bibi Hølge-Hazelton
AIM: To describe whether an action learning-inspired journal club for nurse leaders can develop the leaders' self-perceived competences to support a research culture in clinical nursing practice. BACKGROUND: Development of clinical research capacity and nurse leaders with the requisite competences are key factors in evidence-based health care practice. This study describes how nurse leaders at a large regional hospital took part in a journal club for nurse leaders, with a view to developing their competences to support a nursing research culture in their departments...
August 10, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28793952/maintaining-capacity-for-in-practice-teaching-and-supervision-of-students-and-general-practice-trainees-a-cross-sectional-study-of-early-career-general-practitioners
#20
Nigel Catzikiris, Amanda Tapley, Simon Morgan, Elizabeth G Holliday, Jean Ball, Kim Henderson, Taryn Elliott, Neil Spike, Cathy Regan, Parker Magin
Objectives Expanding learner cohorts of medical students and general practitioner (GP) vocational trainees and the impending retirement of the 'baby boomer' GP cohort threaten the teaching and supervisory capacity of the Australian GP workforce. Engaging newly qualified GPs is essential to sustaining this workforce training capacity. The aim of the present study was to establish the prevalence and associations of in-practice clinical teaching and supervision in early career GPs.Methods The present study was a cross-sectional questionnaire-based study of recent (within 5 years) alumni of three of Australia's 17 regional general practice training programs...
August 10, 2017: Australian Health Review: a Publication of the Australian Hospital Association
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