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https://www.readbyqxmd.com/read/26373981/nurses-experiences-of-hospitalised-patients-sleep-in-sweden-a-qualitative-study
#1
Linda Gellerstedt, Jörgen Medin, Maria Kumlin, Monica Rydell Karlsson
AIMS AND OBJECTIVES: The aim was to describe nurses' experiences of patients' sleep at an emergency hospital and their perceptions of sleep-promoting interventions. BACKGROUND: Promotion of patients' sleep during hospital care is an important intervention for the nursing profession. To promote sleep and to initiate sleep-promoting interventions, nurses need basic knowledge about sleep and its physiology. Therefore, it is of importance to explore and expand knowledge about how nurses experience patients' sleep and how they perceive working with it while providing care...
December 2015: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/25154710/murine-splenic-cd4%C3%A2-%C2%BA-t-cells-induced-by-innate-immune-cell-interactions-and-secreted-factors-develop-antileukemia-cytotoxicity
#2
Megan E Nelles, Joshua M Moreau, Caren L Furlonger, Alexandra Berger, Jeffrey A Medin, Christopher J Paige
Inciting the cellular arm of adaptive immunity has been the fundamental goal of cancer immunotherapy strategies, specifically focusing on inducing tumor antigen-specific responses by CD8(+) cytotoxic T lymphocytes (CTL). However, there is an emerging appreciation that the cytotoxic function of CD4(+) T cells can be effective in a clinical setting. Harnessing this potential will require an understanding of how such cells arise. In this study, we use an IL12-transduced variant of the 70Z/3 leukemia cell line in a B6D2F1 (BDF1) murine model system to reveal a novel cascade of cells and soluble factors that activate anticancer CD4(+) killer cells...
November 2014: Cancer Immunology Research
https://www.readbyqxmd.com/read/25097289/profound-hypoglycemia-%C3%A4-nduced-by-vaccinium-corymbosum-juice-and-laurocerasus-fruit
#3
Ahmet Hamdi Aktan, Abdullah Ozcelik, Erkan Cure, Medine Cumhur Cure, Suleyman Yuce
An emergency intervention was performed in a 75-year-old male patient with hypoglycemic attack and blackout. Although he was diagnosed with prediabetes before 2 years, he did not take any anti-diabetic drug or follow dietary advice. He drank Vaccinium corymbosum L (VC) juice daily with a belief that it increases sexual potency. Before the development of hypoglycemia, the patient had consumed about 500 ml VC juice in addition to eating 200-300 gram of Laurocerasus officinalis (LO) fruit. The measured plasma glucose (PG) level during loss of consciousness was 30 mg/dl...
July 2014: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/24733480/development-and-validation-of-the-afsymp%C3%A2-an-atrial-fibrillation-specific-measure-of-patient-reported-symptoms
#4
Jennie Medin, Rob Arbuckle, Linda Abetz, Katarina Halling, Karoly Kulich, Nils Edvardsson, Karin S Coyne
BACKGROUND: Patients with atrial fibrillation (AF) can be severely incapacitated by symptoms, but validated symptom measures are lacking. The aim of this study was to develop an AF-specific symptom questionnaire (AFSymp™). METHODS: Following a literature review, qualitative interviews with 91 patients (United States [US], n = 30; United Kingdom [UK], n = 16; France, n = 15; Germany, n = 15; Japan, n = 15) with paroxysmal, persistent, and permanent AF were conducted to identify emergent concepts and to develop the items and response options for the AFSymp™...
2014: Patient
https://www.readbyqxmd.com/read/24725258/evaluating-an-early-intervention-in-psychosis-service-for-high-risk-adolescents-symptomatic-and-social-recovery-outcomes
#5
Rebecca Lower, Jonathan Wilson, Evelina Medin, Emma Corlett, Ruth Turner, Karen Wheeler, David Fowler
AIM: This study presents client characteristics and treatment outcomes for a group of young people seen by Central Norfolk Early Intervention Team (CNEIT). The team offers an intensive outreach model of treatment to young people with complex co-morbid emotional, behavioural and social problems, as well as the presence of psychotic symptoms. METHODS: Outcomes include both client self-report and clinician-rated measures. Data are routinely collected at acceptance into service, after 12 months of service and at point of discharge...
June 2015: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/24461249/-psychosocial-aspects-in-a-cohort-of-vertically-transmitted-human-immunodeficiency-virus-infected-adolescents
#6
Cristina García-Navarro, Isabel García, Gabriela Medín, José Tomás Ramos-Amador, Marisa Navarro-Gómez, M José Mellado-Peña, M I de José Gómez, Marisol Cortés, Berta Zamora Crespo, M Angeles Muñoz-Fernandez, Daniel Blázquez Gamero, M Isabel González-Tomé
INTRODUCTION: Thanks to advances in antiretroviral treatment, children with HIV infections through vertical transmission have improved their life expectancy. However, new challenges have emerged. We propose this study in order to determine the psychosocial aspects and knowledge of infections in a cohort of adolescents with vertically transmitted HIV infections. METHODS: Patients with vertically-acquired HIV infection between 12 and 19 years old were included. Data were obtained through semi-structured interviews and a Strengths and Difficulties Questionnaire for emotional and behavioral disorders screening...
December 2014: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/24339567/low-density-lipoprotein-subfraction-carotid-artery-intima-media-thickness-nitric-oxide-and-tumor-necrosis-factor-alpha-are-associated-with-newly-diagnosed-ischemic-stroke
#7
Medine Cumhur Cure, Ahmet Tufekci, Erkan Cure, Serkan Kirbas, Sabri Ogullar, Aynur Kirbas, Huseyin Unal, Suleyman Yuce, Sevim Cakmak
OBJECTIVES: Small dense (sd) low-density lipoprotein (LDL), tumor necrosis factor (TNF) alpha (α), and nitric oxide (NO) have recently emerged as important stroke risk factors. The aim of the study was to investigate the effects of increased levels of small LDL particle size, TNF-α and NO on the developed ischemic stroke and increased carotid artery intima-media thickness (CIMT). MATERIALS AND METHODS: A total of 29 women and 25 men (a total of 54 ischemic stroke patients) and a similar age group of 50 controls (29 females and 21 males) were included in the study...
October 2013: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/24121763/rituximab-for-minimal-change-disease-in-adults-long-term-follow-up
#8
Annette Bruchfeld, Samiha Benedek, Marie Hilderman, Charlotte Medin, Sunna Snaedal-Jonsdottir, Maarit Korkeila
BACKGROUND: Minimal change nephropathy or disease (MCD) accounts for 10-15% of cases of the nephrotic syndrome in adults with frequent relapses occurring in up to 25% of cases. The drug of choice is glucocorticoids (GCs), but GC-dependence is seen in 25-30%. Treatment with rituximab has been found to be effective in relapsing and GC-dependent cases, but little data are available regarding long-term outcome in adults. PATIENTS: We present nine female and seven male patients, ranging from 19 to 73 years of age with multirelapsing, GC-dependent or GC-resistant disease with a kidney biopsy consistent with MCD...
April 2014: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/22684800/turning-tides-prospects-for-more-diversity-in-cognitive-science
#9
Andrea Bender, Sieghard Beller, Douglas L Medin
This conclusion of the debate on anthropology's role in cognitive science provides some clarifications and an overview of emergent themes. It also lists, as cases of good practice, some examples of productive cross-disciplinary collaboration that evince a forward momentum in the relationship between anthropology and the other cognitive sciences.
July 2012: Topics in Cognitive Science
https://www.readbyqxmd.com/read/19520740/progress-and-future-challenges-in-stem-cell-derived-liver-technologies
#10
REVIEW
Donna M Dalgetty, Claire N Medine, John P Iredale, David C Hay
The emergence of regenerative medicine has led to significant advances in the identification and understanding of human stem cells and adult progenitor cells. Both cell populations exhibit plasticity and theoretically offer a potential source of somatic cells in large numbers. Such a resource has an important role to play in the understanding of human development, in modeling human disease and drug toxicity, and in the generation of somatic cells in large numbers for cell-based therapies. Presently, liver transplantation is the only effective treatment for end-stage liver disease...
August 2009: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/19456209/novel-application-of-lentiviral-vectors-towards-treatment-of-graft-versus-host-disease
#11
REVIEW
Matthew D Scaife, Anton Neschadim, D H Fowler, J A Medin
Allogeneic transplantation of hematopoietic stem cells and lymphocytes is a curative treatment for malignant and non-malignant disease. However, the primary complication limiting the safety of transplantation is graft-versus-host disease (GvHD), which is mediated by donor T cells. Strategies for pre- and post-transplant manipulation of graft cells are not yet optimal for balancing GvHD severity with beneficial Graft-versus-Leukemia (GvL) effects. Emerging cell fate control gene therapy (CFCGT)-based strategies, such as 'suicide' gene therapy for donor T cell regulation, can supplement existing transplantation approaches by providing a safety element to reduce GvHD...
June 2009: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/18391263/effects-of-repeated-cpr-training-in-virtual-worlds-on-medical-students-performance
#12
J Creutzfeldt, L Hedman, C Medin, C J Wallin, L Felländer-Tsai
We report on a study that investigates the relationship between repeated training of teams managing a medical emergency (CPR) in a Virtual World and performance outcome measures in a group of 12 medical students. The focus of the training was on individual actions, but also on interaction and behavior in the team. Current CPR training seems to lack important team training aspects which this type of training is addressing. Although a pilot study, we found clear indications of improved performance related to reduced number of errors and an increased CPR efficiency...
2008: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/17602267/current-status-of-tumor-m2-pyruvate-kinase-tumor-m2-pk-as-a-biomarker-of-gastrointestinal-malignancy
#13
REVIEW
Harsha R Hathurusinghe, Kolitha S Goonetilleke, Ajith K Siriwardena
BACKGROUND: Tumor pyruvate kinase M2 (tumor M2-PK) is a key enzyme in the altered metabolism of tumor tissue. In cancer, it is known to be present in high concentrations in malignant tissue, plasma and other body fluids. A commercial enzyme-linked immunosorbent assay (ELISA) method exists for the detection of tumor M2-PK. This study undertakes a systematic review of the current literature on tumor M2-PK as a diagnostic tool and provides an overview of the current usage and scope of this emerging biomarker...
October 2007: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/17377239/implementing-virtual-worlds-for-systematic-training-of-prehospital-cpr-in-medical-school
#14
J Creutzfeldt, L Hedman, C Medin, C J Wallin, A Hendrick, P Youngblood, Wm L Heinrichs, L Felländer-Tsai
We report on a study that investigates the relationship between repeated training of teams managing medical emergencies in the Virtual World and affective learning outcomes in a group of 12 medical students. The focus of the training was on individual actions, but also on interaction and behaviour in the team. Current CPR training seems to lack important team training aspects which this type of training is addressing. We found an increase in flow experience and in self efficacy. This type of training could probably be expanded to other groups for a similar purpose because of its easiness to use, adaptability and interactivity...
2007: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/17269208/lentiviral-vectors-for-gene-therapy-of-heart-disease
#15
REVIEW
Koji Higuchi, Jeffrey A Medin
Technological advances in genetic engineering developed over the past few years have been applied to the research and treatment of cardiovascular diseases. In many animal models, gene therapy has been shown to be an effective treatment schema. Some of these gene therapy treatments are now being applied in clinical trials. Also, as the science of gene therapy has progressed, alternative vector systems such as lentiviruses have been developed and implemented. Here we focus on the emerging role of lentiviral vectors in the treatment of cardiovascular disease...
January 2007: Journal of Cardiology
https://www.readbyqxmd.com/read/10377461/folkecology-and-commons-management-in-the-maya-lowlands
#16
S Atran, D Medin, N Ross, E Lynch, J Coley, E U Ek', V Vapnarsky
Three groups living off the same rainforest habitat manifest strikingly distinct behaviors, cognitions, and social relationships relative to the forest. Only the area's last native Maya reveal systematic awareness of ecological complexity involving animals, plants, and people and practices clearly favoring forest regeneration. Spanish-speaking immigrants prove closer to native Maya in thought, action, and social networking than do immigrant Maya. There is no overriding "local," "Indian," or "immigrant" relationship to the environment...
June 22, 1999: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/9375051/radiological-videoconferencing-in-sweden
#17
M Kehler, P O Bengtsson, M Freitag, B Lindström, J Medin
For the last four years there has been a videoconferencing link between the Karlskrona hospital and the university hospital of Lund. Because of a need to transmit angiographic films, its use has been gradually expanded to become an everyday routine, used for both elective and emergency examinations. During 1994 and 1995, 1121 cases were examined over the video link. Apart from 156 normal cases all were discussed with surgeons, most at 96 weekly conferences but approximately 50 at conferences taking place as soon as possible after the examination...
1996: Journal of Telemedicine and Telecare
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