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https://www.readbyqxmd.com/read/28934662/a-pc-pu-nanoparticle-pu-decellularized-scaffold-composite-vascular-patch-synergistically-optimized-overall-performance-promotes-endothelialization
#1
Jun Zhang, Cheng Liu, Fuling Feng, Dawei Wang, Shuaishuai Lu, Guo Wei, Hong Mo, Tong Qiao
Composite vascular patches have gained increasingly attention due to the limited availability of autologous patches (vascular graft materials made from the blood vessels of the same recipient), the lack of growth capability of nonautologous patches (vascular graft materials made from the blood vessels of a different donor) and the disadvantages of synthetic patches. In this study, we report a highly biocompatible phosphatidylcholine-polyurethane nanoparticle/polyurethane/decellularized scaffold composite vascular patch (PCVP)...
September 6, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28934607/a-visible-light-driven-heterojuncted-composite-wo3-bi12o17cl2-synthesis-characterization-and-improved-photocatalytic-performance
#2
Jiaojiao Zheng, Fei Chang, Mingzhi Jiao, Quan Xu, Baoqing Deng, Xuefeng Hu
Novel visible-light-driven WO3/Bi12O17Cl2 heterojuncted photocatalysts with different mass ratios were successfully fabricated by a facile hydrothermal process and were characterized by XRD, UV-Vis DRS, SEM, TEM, HRTEM, XPS, BET, Raman, PL, and ESR techniques. The original morphology of Bi12O17Cl2 was maintained after the addition of WO3 nanoparticles and the specific surface area values of WBx composites were obviously enlarged. The intimate contact of both components in HRTEM confirmed the generation of smooth phase interface...
September 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28934548/controlling-styrene-maleic-acid-lipid-particles-through-raft
#3
Anton A A Smith, Henriette Elisabeth Autzen, Tomas Laursen, Vincent Wu, Max Yen, Aaron Hall, Scott D Hansen, Yifan Cheng, Ting Xu
The ability of styrene maleic acid copolymers to dissolve lipid membranes into nanosized lipid particles is a facile method of obtaining membrane proteins in solubilized lipid discs while conserving part of its native lipid environment. While the currently used copolymers can readily extract membrane proteins in native nanodiscs, their highly disperse composition is likely to influence the dispersity of the discs as well as the extraction efficiency. In this study, reversible addition fragmentation chain transfer was used to control the polymer architecture and dispersity of molecular weights with a high-precision...
September 21, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28934421/a-zebrafish-model-of-mycobacterium-leprae-granulomatous-infection
#4
Cressida A Madigan, James Cameron, Lalita Ramakrishnan
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in the ectothermic zebrafish. We found that noncaseating granulomas develop rapidly and eventually eradicate infection. rag1 mutant zebrafish, which lack lymphocytes, also form noncaseating granulomas with similar kinetics, but these control infection more slowly...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28934354/synthesis-of-irregular-graphene-oxide-tubes-using-green-chemistry-and-their-potential-use-as-reinforcement-materials-for-biomedical-applications
#5
Ángel Serrano-Aroca, Sanjukta Deb
Micrometer length tubes of graphene oxide (GO) with irregular form were synthesised following facile and green metal complexation reactions. These materials were obtained by crosslinking of GO with calcium, zinc or strontium chlorides at three different temperatures (24, 34 and 55°C) using distilled water as solvent for the compounds and following a remarkably simple and low-cost synthetic method, which employs no hazardous substances and is conducted without consumption of thermal or sonic energy. These irregular continuous GO networks showed a very particular interconnected structure by Field Emission Scanning Electron Microscopy with Energy-Disperse X-Ray Spectroscopy for elemental analysis and High-resolution Transmission Electron Microscopy with Scanning Transmission Electron Microscope Dark Field Imaging, and were analysed by Raman Spectroscopy...
2017: PloS One
https://www.readbyqxmd.com/read/28934303/characterization-of-the-cpap-treated-patient-population-in-catalonia
#6
Cecilia Turino, Sandra Bertran, Ricard Gavaldá, Ivan Teixidó, Holger Woehrle, Montserrat Rué, Francesc Solsona, Joan Escarrabill, Cristina Colls, Anna García-Altés, Jordi de Batlle, Manuel Sánchez de-la-Torre, Ferran Barbé
There are different phenotypes of obstructive sleep apnoea (OSA), many of which have not been characterised. Identification of these different phenotypes is important in defining prognosis and guiding the therapeutic strategy. The aim of this study was to characterise the entire population of continuous positive airway pressure (CPAP)-treated patients in Catalonia and identify specific patient profiles using cluster analysis. A total of 72,217 CPAP-treated patients who contacted the Catalan Health System (CatSalut) during the years 2012 and 2013 were included...
2017: PloS One
https://www.readbyqxmd.com/read/28934285/cost-of-illness-of-cholera-to-households-and-health-facilities-in-rural-malawi
#7
Patrick G Ilboudo, Xiao Xian Huang, Bagrey Ngwira, Abel Mwanyungwe, Vittal Mogasale, Martin A Mengel, Philippe Cavailler, Bradford D Gessner, Jean-Bernard Le Gargasson
Cholera remains an important public health problem in many low- and middle-income countries. Vaccination has been recommended as a possible intervention for the prevention and control of cholera. Evidence, especially data on disease burden, cost-of-illness, delivery costs and cost-effectiveness to support a wider use of vaccine is still weak. This study aims at estimating the cost-of-illness of cholera to households and health facilities in Machinga and Zomba Districts, Malawi. A cross-sectional study using retrospectively collected cost data was undertaken in this investigation...
2017: PloS One
https://www.readbyqxmd.com/read/28934258/reports-of-unintended-consequences-of-financial-incentives-to-improve-management-of-hypertension
#8
Sylvia J Hysong, Richard SoRelle, Kristen Broussard Smitham, Laura A Petersen
BACKGROUND: Given the increase in financial-incentive programs nationwide, many physicians and physician groups are concerned about potential unintended consequences of providing financial incentives to improve quality of care. However, few studies examine whether actual unintended consequences result from providing financial incentives to physicians. We sought to document the extent to which the unintended consequences discussed in the literature were observable in a randomized clinical trial (RCT) of financial incentives...
2017: PloS One
https://www.readbyqxmd.com/read/28934228/knowledge-about-tuberculosis-transmission-and-prevention-and-perceptions-of-health-service-utilization-among-index-cases-and-contacts-in-brazil-understanding-losses-in-the-latent-tuberculosis-cascade-of-care
#9
Flavia Matos Salame, Márcia Danielle Ferreira, Marcia Teresa Belo, Eleny Guimarães Teixeira, Marcelo Cordeiro-Santos, Ricardo Arraes Ximenes, Maria de Fátima Militão de Albuquerque, Philip C Hill, Dick Menzies, Anete Trajman
INTRODUCTION: Tuberculosis contacts are candidates for active and latent tuberculosis infection screening and eventual treatment. However, many losses occur in the different steps of the contacts' cascade of care. Reasons for this are poorly understood. OBJECTIVE: To describe the different steps where losses in the contact cascade occur and to explore knowledge and attitudes regarding tuberculosis transmission/prevention and perceptions about tuberculosis services in order to understand the reasons for losses from the tuberculosis service users' perspective...
2017: PloS One
https://www.readbyqxmd.com/read/28934218/prevalence-of-intestinal-parasites-among-inmates-in-midwest-brazil
#10
Larissa Gabrielle Curval, Adriana de Oliveira França, Henrique Jorge Fernandes, Rinaldo Pôncio Mendes, Lídia Raquel de Carvalho, Minoru German Higa, Eduardo de Castro Ferreira, Maria Elizabeth Cavalheiros Dorval
BACKGROUND: Intestinal parasitic infections constitute a public health issue in developing countries, with prevalence rates as high as 90%, a figure set to escalate as the socioeconomic status of affected populations deteriorates. Investigating the occurrence of these infections among inmates is critical, since this group is more vulnerable to the spread of a number of infectious illnesses. METHODS: This cross-sectional, analytical, quantitative study was conducted in July 2015 at prison facilities located in Midwest Brazil to estimate the prevalence of parasitic infection among inmates...
2017: PloS One
https://www.readbyqxmd.com/read/28934201/forensic-genetics-and-genomics-much-more-than-just-a-human-affair
#11
REVIEW
Miguel Arenas, Filipe Pereira, Manuela Oliveira, Nadia Pinto, Alexandra M Lopes, Veronica Gomes, Angel Carracedo, Antonio Amorim
While traditional forensic genetics has been oriented towards using human DNA in criminal investigation and civil court cases, it currently presents a much wider application range, including not only legal situations sensu stricto but also and, increasingly often, to preemptively avoid judicial processes. Despite some difficulties, current forensic genetics is progressively incorporating the analysis of nonhuman genetic material to a greater extent. The analysis of this material-including other animal species, plants, or microorganisms-is now broadly used, providing ancillary evidence in criminalistics in cases such as animal attacks, trafficking of species, bioterrorism and biocrimes, and identification of fraudulent food composition, among many others...
September 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28934141/facile-synthesis-of-zno-nanoparticles-on-nitrogen-doped-carbon-nanotubes-as-high-performance-anode-material-for-lithium-ion-batteries
#12
Haipeng Li, Zhengjun Liu, Shuang Yang, Yan Zhao, Yuting Feng, Zhumabay Bakenov, Chengwei Zhang, Fuxing Yin
ZnO/nitrogen-doped carbon nanotube (ZnO/NCNT) composite, prepared though a simple one-step sol-gel synthetic technique, has been explored for the first time as an anode material. The as-prepared ZnO/NCNT nanocomposite preserves a good dispersity and homogeneity of the ZnO nanoparticles (~6 nm) which deposited on the surface of NCNT. Transmission electron microscopy (TEM) reveals the formation of ZnO nanoparticles with an average size of 6 nm homogeneously deposited on the surface of NCNT. ZnO/NCNT composite, when evaluated as an anode for lithium-ion batteries (LIBs), exhibits remarkably enhanced cycling ability and rate capability compared with the ZnO/CNT counterpart...
September 21, 2017: Materials
https://www.readbyqxmd.com/read/28934124/n-halamine-biocidal-materials-with-superior-antimicrobial-efficacies-for-wound-dressings
#13
Buket Demir, Roy M Broughton, Mingyu Qiao, Tung-Shi Huang, S D Worley
This work demonstrated the successful application of N-halamine technology for wound dressings rendered antimicrobial by facile and inexpensive processes. Four N-halamine compounds, which possess different functional groups and chemistry, were synthesized. The N-halamine compounds, which contained oxidative chlorine, the source of antimicrobial activity, were impregnated into or coated onto standard non-antimicrobial wound dressings. N-halamine-employed wound dressings inactivated about 6 to 7 logs of Staphylococcus aureus and Pseudomonas aeruginosa bacteria in brief periods of contact time...
September 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28933979/geographic-access-to-cancer-care-and-mortality-among-adolescents
#14
Eric Tai, Elaine Hallisey, Lucy A Peipins, Barry Flanagan, Natasha Buchanan Lunsford, Grete Wilt, Shannon Graham
PURPOSE: Adolescents with cancer have had less improvement in survival than other populations in the United States. This may be due, in part, to adolescents not receiving treatment at Children's Oncology Group (COG) institutions, which have been shown to increase survival for some cancers. The objective of this ecologic study was to examine geographic distance to COG institutions and adolescent cancer mortality. METHODS: We calculated cancer mortality among adolescents and sociodemographic and healthcare access factors in four geographic zones at selected distances surrounding COG facilities: Zone A (area within 10 miles of any COG institution), Zones B and C (concentric rings with distances from a COG institution of >10-25 miles and >25-50 miles, respectively), and Zone D (area outside of 50 miles)...
September 21, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28933859/copper-catalyzed-cascade-cyclization-of-1-7-enynes-toward-trifluoromethyl-substituted-1-h-spiro-azirine-2-4-quinolin-2-3-h-ones
#15
Qiang Meng, Fei Chen, Wei Yu, Bing Han
A novel method for the synthesis of trifluoromethyl-containing 1'H-spiro[azirine-2,4'-quinolin]-2'(3'H)-ones by a CF3-radical-triggered tandem reaction of benzene-linked 1,7-enynes is described. This protocol utilizes 1-trifluoromethyl-1,2-benziodoxole as the trifluoromethylating reagent and TMSN3 as the aminating reagent. By this method, various potentially bioactive trifluoromethylated 1'H-spiro[azirine-2,4'-quinolin]-2'(3'H)-ones were facilely synthesized via a radical cascade process.
September 21, 2017: Organic Letters
https://www.readbyqxmd.com/read/28933849/h2so4-mediated-stereocontrolled-annulation-of-oxygenated-naphthalenes-and-4-alkenols-one-pot-synthesis-of-tetanthrenes
#16
Meng-Yang Chang, Yu-Ting Hsiao
H2SO4 mediated one-pot stereocontrolled (4+2) annulation of 4-alkenols and oxygenated naphthalenes provided tetanthrenes in CH2Cl2 at 25 degrees C for 10 h. The use of various Brønsted acids or Lewis acids was investigated for a facile and efficient transformation. A plausible mechanism has been proposed.
September 21, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28933813/facile-and-effective-coloration-of-dye-inert-carbon-fiber-fabrics-with-tunable-colours-and-excellent-laundering-durability
#17
Fengxiang Chen, Huiyu Yang, Ke Li, Bo Deng, Qingsong Li, Xin Liu, Binghai Dong, Xingfang Xiao, Dong Wang, Yong Qin, Shi-Min Wang, Ke-Qin Zhang, Weilin Xu
Carbon fiber is a good candidate in various applications, including military, structural, sports equipment, energy storage, and infrastructure. Coloring of carbon fiber has been a big challenge for decades due to their high degrees of crystallization and insufficient chemical affinity to dyes. Here, multicolored carbon fiber fabrics (CFFs) are fabricated using a feasible, effective atomic layer deposition (ALD) technique. The vibrant and uniform structural colors originate from thin film interference is simply regulated by controlling the thickness of comformal TiO2 coatings on the surface of black carbon fibers (CFs)...
September 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28933627/primary-care-for-mentally-ill-adults-in-acute-residential-treatment-facilities
#18
Linda Chafetz, Gerri Collins-Bride
Psychiatric bed capacity has decreased nationally with an impact on the number and the types of patients admitted to acute in-patient units. Acute residential programs provide alternatives to hospitals for patients with problems that do not meet criteria for admission. However, these settings may not have resources to respond to the medical co-morbidities associated with severe mental illness. To understand the medical needs of patients in these settings, this research examined data from a nurse-managed primary care outreach service...
September 21, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28933532/sb2o3-nanoparticles-anchored-on-graphene-sheets-via-alcohol-dissolution-reprecipitation-method-for-excellent-lithium-storage-properties
#19
Xiaozhong Zhou, Zhengfeng Zhang, Xiaofang Lu, Xueyan Lv, Guofu Ma, Qingtao Wang, Ziqiang Lei
Sb2O3 nanoparticles are uniformly anchored on reduced graphene oxide (rGO) sheets via a facile and eco-friendly route based on alcohol dissolution-reprecipitation method. Such obtained Sb2O3/rGO composite demonstrates a highly reversible specific capacity (1355 mA h g-1 at 100 mA g-1), good rate capability, and superior cycle life (525 mA h g-1 after 700 cycles at 600 mA g-1) when used an anode electrode for lithium-ion batteries (LIBs). The outstanding electrochemical properties of Sb2O3/rGO composite could be attributed to its unique structure which the strong electronic coupling effect between Sb2O3 and rGO and thus leads to enhanced electronic conductivity, structure stability and electrochemical activity during reversible conversion-alloying reactions...
September 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28933505/sbvo4-nanoparticles-synthesized-via-three-facile-one-pot-methods-controllable-morphologies-and-superhydrophobic-coatings
#20
Ximeng Liu, Xiaojuan Yang, Feng Li, Taohai Li, Wei Cao
Inert colloidal SbVO4 with special morphologies is promising for practical superhydrophobic coatings. However, its conventional synthesis suffers from harsh preparation conditions, limiting the material applications. Herein, by using K6V10O28·9H2O as a novel vanadium source, SbVO4 nanoparticles were prepared through three different facile methods: hydrothermal method, reflux method and ultrasonic method. The pH values of the reaction environment were tuned as the only variable to shape the final products. Colloidal morphologies can be engineered to microflakes, or amalgamations of nanoparticles...
September 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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